Busch Lab

ZMP

mdm1

Ensembl ID:
ENSDARG00000045675
ZFIN ID:
ZDB-GENE-041210-117
Description:
Nuclear protein MDM1 [Source:UniProtKB/Swiss-Prot;Acc:Q5RHU7]
Human Orthologue:
MDM1
Human Description:
Mdm1 nuclear protein homolog (mouse) [Source:HGNC Symbol;Acc:29917]
Mouse Orthologue:
Mdm1
Mouse Description:
transformed mouse 3T3 cell double minute 1 Gene [Source:MGI Symbol;Acc:MGI:96951]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa38429 Nonsense Mutation detected in F1 DNA Not yet available
sa33423 Nonsense Mutation detected in F1 DNA Not yet available
sa18778 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa38429
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102006 Nonsense 185 495 5 11
ENSDART00000102010 Nonsense 185 656 5 13
ENSDART00000132971 Nonsense 185 667 5 14

The following transcripts of ENSDARG00000045675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 12628315)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 13564942
GRCz11 4 13563791
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTTCATTGCAGCTCCTTGAGTTTTGAATTATTTTACATCTGCTAGATGT[T/A]ATACAGTAACAACAGAGCCATCCCACCCTTCAAAACAAACCCAGTGATTA
Long Flanking Sequence:
AACTCCCCAAAGATGATTTATTGGATTAAGATGTAGTGACTGTGAGGGCCATTTGAGTACAGTGAACTCATTGTCATGTTCAAGATACCAGCCTGTCTGGCATTAACAACCATGCCACGTTCAAAGTCACTTAAATCACCTTTCTTCCCGATTCTGATGCTTGGTTTGAATTGCAGCAGATCGTCTTGACCATGTCTATATGCCTAAATGCATTGAGTTGCTGCCATGTGATTGGCTGATTAGACATTTGCGCTAAAAAGCAGTTGGACAGGTGTATCTAATAAAGTGGCCGGTGAGTGTATATTCTAACATTAATGGTTATTTTATAATGTTGTTTGTTTGCAAGATTTAATTCTTTAAAATGGTATAGCTTATCTTATTAAACTGATTATTAATATGTTATTACAATTAGATCTTTTTCAAGTAATTATCTGAATACCATAGCCATCAGGTTCATTGCAGCTCCTTGAGTTTTGAATTATTTTACATCTGCTAGATGT[T/A]ATACAGTAACAACAGAGCCATCCCACCCTTCAAAACAAACCCAGTGATTATGGAGAGCGAGTACAAGAGAAGTTTCAAAGGATCGCCTCTTCCCAGGCCACCACGCTTGAGGCGAGATGTTGAACAGTATGAGGTCCCAGAGTTTCTAACAGAGAGCAAAACCCCAGAGAAGGTACACAGAAATATACCCTCTCAGTTCATTCACATACATCAATCATGAATGCAAACTTTCCAGGTATTACAGCGTCAGTATGGGATCTGGAAAATCTAGTTTCAATAACATATGTTATTTCCTTATAGTTTTTTTTCACGTGCTCTGCAACGTATAGAGAGGAAGTATACATTTACTAAAATGTTTGCACCTTTGACATAGTATTTCTGGCTCTTTTGCCTAAATGCCCATCAAACCAGAGTAAGAGAAAGAAGAAGAAGAAGGAGCGACCACACAGCAGGAAGTCAAGCCCAGAACAAGAAGTTGCCTATCTACAGCAACAGGAAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33423
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102006 Nonsense 213 495 5 11
ENSDART00000102010 Nonsense 213 656 5 13
ENSDART00000132971 Nonsense 213 667 5 14

The following transcripts of ENSDARG00000045675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 12628231)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 13564858
GRCz11 4 13563707
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACAAACCCAGTGATTATGGAGAGCGAGTACAAGAGAAGTTTCAAAGGAT[C/A]GCCTCTTCCCAGGCCACCACGCTTGAGGCGAGATGTTGAACAGTATGAGG
Long Flanking Sequence:
ATACCAGCCTGTCTGGCATTAACAACCATGCCACGTTCAAAGTCACTTAAATCACCTTTCTTCCCGATTCTGATGCTTGGTTTGAATTGCAGCAGATCGTCTTGACCATGTCTATATGCCTAAATGCATTGAGTTGCTGCCATGTGATTGGCTGATTAGACATTTGCGCTAAAAAGCAGTTGGACAGGTGTATCTAATAAAGTGGCCGGTGAGTGTATATTCTAACATTAATGGTTATTTTATAATGTTGTTTGTTTGCAAGATTTAATTCTTTAAAATGGTATAGCTTATCTTATTAAACTGATTATTAATATGTTATTACAATTAGATCTTTTTCAAGTAATTATCTGAATACCATAGCCATCAGGTTCATTGCAGCTCCTTGAGTTTTGAATTATTTTACATCTGCTAGATGTTATACAGTAACAACAGAGCCATCCCACCCTTCAAAACAAACCCAGTGATTATGGAGAGCGAGTACAAGAGAAGTTTCAAAGGAT[C/A]GCCTCTTCCCAGGCCACCACGCTTGAGGCGAGATGTTGAACAGTATGAGGTCCCAGAGTTTCTAACAGAGAGCAAAACCCCAGAGAAGGTACACAGAAATATACCCTCTCAGTTCATTCACATACATCAATCATGAATGCAAACTTTCCAGGTATTACAGCGTCAGTATGGGATCTGGAAAATCTAGTTTCAATAACATATGTTATTTCCTTATAGTTTTTTTTCACGTGCTCTGCAACGTATAGAGAGGAAGTATACATTTACTAAAATGTTTGCACCTTTGACATAGTATTTCTGGCTCTTTTGCCTAAATGCCCATCAAACCAGAGTAAGAGAAAGAAGAAGAAGAAGGAGCGACCACACAGCAGGAAGTCAAGCCCAGAACAAGAAGTTGCCTATCTACAGCAACAGGAAGTGAAATCACCCCACAACCTGAAAGACCCTTCACCAAAGGTTATGAGGTGACTGTTGTGTTTTTACAGGATGTGCAAAAATAACAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18778
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000102006 None None 495 None 11
ENSDART00000102010 None None 656 None 13
ENSDART00000132971 Nonsense 327 667 8 14

The following transcripts of ENSDARG00000045675 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 12624929)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 13561556
GRCz11 4 13560405
KASP Assay ID:
2259-4674.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTGGTCTGTATGGTTAATCTTGCAGGGGTGTGATGGTTTTCACGAGTG[G/A]TATCATGAGGTAACATTTCACCTGTTACTTGCATCCTCTCACTGCTTCAG
Long Flanking Sequence:
TTCACAAATGGTGACTTCCTTTGTGTGGTTTTAAGCCTTTCTGAGTTTATTTCTTCTGTTAGACACAAATTAAGATATTCTGAAGAATGCTGCTTGTTGAGACCGATTGACTTCTGCAGTAGGAAAAAAACCCAGCAACCAGCATTCTTCAAAATACCTTCTTTTGTTTTCCAACAGAAGAAAGAAACTCAAACAGGTTTGGAACAAGTGAAGGGGGAGAAAGTGATGACAGATTTAAAATAATTTGGGTGAACTATCTCTTTAAGTCCCCAAAATTCTGCAAGTGAAATCAAGGCAAGAACCCATATGAATGTCAAATTAGTAGTTTGTTTGAAGTTGCTGAAACAAACTCACTTTAGGTTACTTTAGATGGTATATCAGGGCATGCAAGCTGTAGAATGGAGTGAAAGTGTCAGAGTTGCTAGAGTATGGCAAGATACTCTCTCTAATCACTGGTCTGTATGGTTAATCTTGCAGGGGTGTGATGGTTTTCACGAGTG[G/A]TATCATGAGGTAACATTTCACCTGTTACTTGCATCCTCTCACTGCTTCAGATCTCTCAACAGACGCTTTAATTTGCTTATGTGTCTGTTCTGTGCTGCTTCAGAAAATGTATGACATCATTGAAAGTTCGATTGTATGGACCTAGATTTGATCATGAGTGTGTGTGTGTGTGTATGTGTGTGCACGCATGTGGTGTATCAAGATGTTATCTGTCAGCATGTACAGAAACTTTGAAGTTGTCTGTGGTTTTGTTGGTAAATTTTTTTCTGTTTCTTGCACTTTCAGGTGTCTGGTAATCTTGTATTGACTTAAGATTTACTCAGTGATTATATACAAGTATATACAAATTTATAGGTGCAGTTTAGATGCATTTATTCATTTAGGTAATTCATGAATTTATGATTTTTTTAATTAGATTAGAAAAGCCTACAATATTGTTACATTTTAAATAATGAATAATGAAACACAATTAGCTTAAAAGCAAAATTGGCAGGGGATAA
Associated Phenotype:
Not determined