Busch Lab

ZMP

lrmp

Ensembl ID:
ENSDARG00000045574
ZFIN ID:
ZDB-GENE-041210-152
Description:
Novel protein similar to vertebrate lymphoid-restricted membrane protein (LRMP) [Source:UniProtKB/Tr
Human Orthologue:
LRMP
Human Description:
lymphoid-restricted membrane protein [Source:HGNC Symbol;Acc:6690]
Mouse Orthologue:
Lrmp
Mouse Description:
lymphoid-restricted membrane protein Gene [Source:MGI Symbol;Acc:MGI:108424]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa2146 Nonsense F2 line generated Not yet available
sa38436 Nonsense Mutation detected in F1 DNA Not yet available
sa33441 Nonsense Mutation detected in F1 DNA Not yet available
sa20251 Essential Splice Site Available for shipment Available now
sa14727 Nonsense Available for shipment Available now
sa38435 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa2146
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067007 Nonsense 125 1447 1 36
ENSDART00000131973 None None 217 None 6
ENSDART00000135730 Nonsense 125 1447 2 37
ENSDART00000147853 None None 271 None 9

The following transcripts of ENSDARG00000045574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 16346058)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 17288898
GRCz11 4 17277874
KASP Assay ID:
554-2505.1 (used for ordering genotyping assays)
KASP Sequence:
ACATTGGGGACATTAGGCACAATTGGAGACAGGAGAACATCAGGAACCTA[C/A]AGCAGACCATTTCGGCGKAACTGCTCCACCCCATCGGCCCARACTGGGGA
Long Flanking Sequence:
TCATATATCAACTAATTAAATAATATGTAATCTAATATATTTGACCAATTACTAGTTGCTCTTTTCTACAACTTTAATCTAATTAACTCCTGTAGGTCGAGGCTTTCTCTCTTGTCCCGGTCCACCATGGATGTCGGAGTGACCCCGAGACGACACAATCCAGTGGACAGCATCTGCCGCAAGCTGCAGACCATTCAGAGGCGAGACCAAGAAATTAATTCACCCTTTCAGATCCCTAAATTCCAGACAAACAGCTACGACAGCCCTCACTCAGGCCTACGCTTCAACCTGGAGGCCATCCTGAAGAAGCATACTGTCCGACCTGACGACTCTGACTCTGCGTCCTCTGCGGGGATGCTGACCCCCACAGCTTCCCCTGGACCGGGGTCTTCCTGCAACACCCCTCGTGCTCCTATTACTCCAGTCAATGCCACCTATAGCATCACAAGCACATTGGGGACATTAGGCACAATTGGAGACAGGAGAACATCAGGAACCTA[C/A]AGCAGACCATTTCGGCGTAACTGCTCCACCCCATCGGCCCAGACTGGGGATAATTACTTTAACTTTACCCCACGCTACTCCACACAATCCCAGGGACCTGACACAGATGTAAGGACCTCAAAGATTCCAACTCCTGGGTTGTTCTCATACAACTTGAACTTCTCCTCGGATATTTCCAACATGGACAGTGAACTCGCCTACCCAGCCCTCGTGGTCAAGAGACTTTCACTGGGCGAGGGTAATGAGTCATCTCCTTTTTTTCTGTCCTTTTCATGTACATGTTTTGCTAAAAGTGTTTTCTTTTCTTGGGTTTTGAACAGGATCTCTGTTTACCTCCGAGCCCAAAAAGGAGAGCATGGCAGAGGTCAGTCTGATCTGTGAGGAAGATCTGTTGGACACAATTTTTCAGGCCTGTGACACACAGTGCAGAGGTATACACTTCTCTCCCACACTGCTTTTATGCTATGTAACTTAACATGATGACATTATGGGGGAAAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38436
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067007 Nonsense 154 1447 1 36
ENSDART00000131973 None None 217 None 6
ENSDART00000135730 Nonsense 154 1447 2 37
ENSDART00000147853 None None 271 None 9

The following transcripts of ENSDARG00000045574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 16345973)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 17288813
GRCz11 4 17277789
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGGCCCAGACTGGGGATAATTACTTTAACTTTACCCCACGCTACTCCACA[C/T]AATCCCAGGGACCTGACACAGATGTAAGGACCTCAAAGATTCCAACTCCT
Long Flanking Sequence:
ACTCCTGTAGGTCGAGGCTTTCTCTCTTGTCCCGGTCCACCATGGATGTCGGAGTGACCCCGAGACGACACAATCCAGTGGACAGCATCTGCCGCAAGCTGCAGACCATTCAGAGGCGAGACCAAGAAATTAATTCACCCTTTCAGATCCCTAAATTCCAGACAAACAGCTACGACAGCCCTCACTCAGGCCTACGCTTCAACCTGGAGGCCATCCTGAAGAAGCATACTGTCCGACCTGACGACTCTGACTCTGCGTCCTCTGCGGGGATGCTGACCCCCACAGCTTCCCCTGGACCGGGGTCTTCCTGCAACACCCCTCGTGCTCCTATTACTCCAGTCAATGCCACCTATAGCATCACAAGCACATTGGGGACATTAGGCACAATTGGAGACAGGAGAACATCAGGAACCTACAGCAGACCATTTCGGCGTAACTGCTCCACCCCATCGGCCCAGACTGGGGATAATTACTTTAACTTTACCCCACGCTACTCCACA[C/T]AATCCCAGGGACCTGACACAGATGTAAGGACCTCAAAGATTCCAACTCCTGGGTTGTTCTCATACAACTTGAACTTCTCCTCGGATATTTCCAACATGGACAGTGAACTCGCCTACCCAGCCCTCGTGGTCAAGAGACTTTCACTGGGCGAGGGTAATGAGTCATCTCCTTTTTTTCTGTCCTTTTCATGTACATGTTTTGCTAAAAGTGTTTTCTTTTCTTGGGTTTTGAACAGGATCTCTGTTTACCTCCGAGCCCAAAAAGGAGAGCATGGCAGAGGTCAGTCTGATCTGTGAGGAAGATCTGTTGGACACAATTTTTCAGGCCTGTGACACACAGTGCAGAGGTATACACTTCTCTCCCACACTGCTTTTATGCTATGTAACTTAACATGATGACATTATGGGGGAAAAATATAATGCTTGCTAAGCAAAACTATGCCGATACTAGTTTTCAGCCATATTATGCATGATGAACTTGTTCGTCTTGGTTCTCACTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33441
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067007 Nonsense 454 1447 8 36
ENSDART00000131973 None None 217 None 6
ENSDART00000135730 Nonsense 454 1447 9 37
ENSDART00000147853 None None 271 None 9

The following transcripts of ENSDARG00000045574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 16340357)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 17283197
GRCz11 4 17272173
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTATAGGAACGTGAAAACCAAAGCCTCATATCCAAGATTGCTGCTTTA[C/T]AAGAGGAGGTATGACTCAGTACATGTAATTAATCCAAATGACCAGGTTAA
Long Flanking Sequence:
ATACTTATTTATTTTTACATCTGAATGTTCAGATTCCATAACATGTCTTTAGACTCACTACCATCTCTAATCCTGTAGGGGGCAGCAATTATTGCAGAAGGAGAAGATGCTTAAAGAAGAAGTTGAGGAGATGAAGCTGAGTCTGACATCTTCAGAAGAAAGCCGAGCTCAGGCCGCAGCTCAAAGAAAACAGATGGTGCGACCCTCTCACCTCATTGACGGCAGTTCAAATGTTAATCAGTCAAGTTATGAAACTCATAAACTAATGCAAACAGATAACAAGCTGTATGATCATAATGAGATTGATAGTTGTATTATATTAACCAAGCATATACAAACATTTAGAGTAAACAAATCTAGCTGCCGGATGCACACTATCTTGCTAGTAATATTGACATTGACAATATGTGTTATTAAATCAAACATGAGCACATTATATAACCTTTGCTTTTTTATAGGAACGTGAAAACCAAAGCCTCATATCCAAGATTGCTGCTTTA[C/T]AAGAGGAGGTATGACTCAGTACATGTAATTAATCCAAATGACCAGGTTAAATAGTCAACATTCATCTCCAATTCCCTTTTTTCTTATTAAGAACATGAAAGTGACCCTGGAGGCAGAGGAACTTCAGAAAAAGATGAATGACCTTTGTGACCTTAATGCTGATCTTCAGGTAGGCTCGGTTTTAGTTCACTCATTCATCATCTTATGCCCCCCCTAAAATACATCTGTTATGGTGGTTAATATTTTTCTATACACTCAGGTTCAAATTCATTCATTTGATGCCATTCTGGCTGATAAGGAGTCATTAATTCAGGAGGTCAGTTATTGCGTATCACTAAAAGAATGATCAAAATAATATCCATGTCACTCTTAATGTACAAATTAAAGCCAAGTGATTTGATTAATTGTGCTTTCCTCCAATCATTACTTGGAATTGTTTAGTGTTATCATTATTCTTTTGGTTATGTTTATATAACTGGCCATCATATAAAATTATATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20251
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067007 Essential Splice Site 501 1447 10 36
ENSDART00000131973 None None 217 None 6
ENSDART00000135730 Essential Splice Site 501 1447 11 37
ENSDART00000147853 None None 271 None 9

The following transcripts of ENSDARG00000045574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 16340040)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 17282880
GRCz11 4 17271856
KASP Assay ID:
2259-4786.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCATTCATTTGATGCCATTCTGGCTGATAAGGAGTCATTAATTCAGGAG[G/A]TCAGTTATTGCGTATCACTAAAAGAATGATCAAAATAATATCCATGTCAC
Long Flanking Sequence:
TATTAACCAAGCATATACAAACATTTAGAGTAAACAAATCTAGCTGCCGGATGCACACTATCTTGCTAGTAATATTGACATTGACAATATGTGTTATTAAATCAAACATGAGCACATTATATAACCTTTGCTTTTTTATAGGAACGTGAAAACCAAAGCCTCATATCCAAGATTGCTGCTTTACAAGAGGAGGTATGACTCAGTACATGTAATTAATCCAAATGACCAGGTTAAATAGTCAACATTCATCTCCAATTCCCTTTTTTCTTATTAAGAACATGAAAGTGACCCTGGAGGCAGAGGAACTTCAGAAAAAGATGAATGACCTTTGTGACCTTAATGCTGATCTTCAGGTAGGCTCGGTTTTAGTTCACTCATTCATCATCTTATGCCCCCCCTAAAATACATCTGTTATGGTGGTTAATATTTTTCTATACACTCAGGTTCAAATTCATTCATTTGATGCCATTCTGGCTGATAAGGAGTCATTAATTCAGGAG[G/A]TCAGTTATTGCGTATCACTAAAAGAATGATCAAAATAATATCCATGTCACTCTTAATGTACAAATTAAAGCCAAGTGATTTGATTAATTGTGCTTTCCTCCAATCATTACTTGGAATTGTTTAGTGTTATCATTATTCTTTTGGTTATGTTTATATAACTGGCCATCATATAAAATTATATTTGTCCAGTATTATAACAGAACTGACTTTTTCTCCTCTAGAAAAATAAACAGATGGATGAACTAAAGGTGGCCGTTGTGGAGTATTCATCAGTTACAGAGGTGATCTTAAATTCTGGTTTTAAAGGGTGGTTCATACAGCAGCATTTTAAAACTTTTGCTAATGATTAGTTTTGTGAATGTTTGTATTAAAAAAAAACTTTTACATTTTTCATAAAATGCTGCTGATTAGTGTTTAACATCTACTCAATCTATCAACCACTACCCCAAGATGTTTTTGCATGTTTACCATCTGCTAAACTATTCTTTTTGTGATTAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14727
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067007 Nonsense 608 1447 14 36
ENSDART00000131973 None None 217 None 6
ENSDART00000135730 Nonsense 608 1447 15 37
ENSDART00000147853 None None 271 None 9

The following transcripts of ENSDARG00000045574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 16338200)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 17281040
GRCz11 4 17270016
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGACTCTAGATCGTGAGGTTCTTCTGCTTCTTCAAGGCCCTACTCCAGAG[C/T]AGCTGTCWCTGGAGTTTAAATCTCTGATCAGCAGATTGGTAACTAAACTA
Long Flanking Sequence:
AAAATATATAAGCCATATAAAAAATGTGTGCTATTAGTTTTAAAAATAAATGTATTAATAGGAATGTGTTCACGTTGTGTGTGTGTGACTTTTGGTCTTTCTTTCGAATAAAACGTTAAACCAAGGTCCAAAGGTCCTAATCATTAAAAATCCCAGGATGTCCTTCGAAATGAGTAGTGGTTTAACCCCATCATCCTGGACAAGTTTGCCCACTGGCCTTAGTCCGACGTGGCCTCTTAACCATCCCTATATCATAATTGGTCCTCTCCATCAATTAGCTACTGTGTGGTGTGTGGTCTGGATGAGGAGATTCCCCCAAATGTGTAAAGCGGTTTGAGTGTACAGAAAAGCGCTATATAAATGTAAGGAATTATTATTATTGTGTGTGTGCATTTGTGCAGGGTTTGGAGCATCTGTCCACTTCTGTCTGTTTTGCATCGTCTCTGGATGAGACTCTAGATCGTGAGGTTCTTCTGCTTCTTCAAGGCCCTACTCCAGAG[C/T]AGCTGTCTCTGGAGTTTAAATCTCTGATCAGCAGATTGGTAACTAAACTAGCCAACTATTACACTTGCACAGCTTAAGCACTCTTCACACCGAGGATGGCAACTATTATATTAGTAAATAGGCATTTATTTAAATTGTTCCAAATGTAAAAGGTTTCACAAATTATTTGAAAACTGCAGTCATCAAAGCTGTTGCACCAACAGAATACTGTAAAATTGTCTGCTTTAAAAAGACCTTTAGTATTGTGTTTAATTCACCTACACCTTTTTTTGTGATTCATAATGTTGTAGACTGTTCACAGTGTGTCACACATGAATCGTTTCAGAAAAGGGAATTTAAAGAAGATGGCCTGACCTTTCTCACAGCAATCAGAAGCCTTACAGAGAACAGTGAAACTCAGGAGGCCAACACTGACCTCAAGATGCAGGTGACAGGATTTTATTCGCTTAAGACATGTCTGACAGAGGCAGGAAACATTTTGTATGTGTATGTAGATATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa38435
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000067007 Nonsense 1333 1447 35 36
ENSDART00000131973 None None 217 None 6
ENSDART00000135730 Nonsense 1333 1447 36 37
ENSDART00000147853 None None 271 None 9

The following transcripts of ENSDARG00000045574 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 4 (position 16324587)
Other Location(s):
Assembly Chromosome Position
GRCz10 4 17267427
GRCz11 4 17256403
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTGCGCTGCGAGAGAGGATGTCATGGTTGTGTGTCGACCGCTTTACAG[G/A]AACATGGCAGCCAAGAGGCCACCGCTAAAGCGCTTTGTTAGCTCTGGTAC
Long Flanking Sequence:
TAGCCGACGTATTAGTATAGCCACCATTCCCCGCAGTATTGGAGGACAGACCCATTTTGATATGGTGAGGAGTTTATAATCTTGTAATATAGATGGTTTTGGTAGACATGAAGTGGAATATCTAAAAAAAAAACGGTTGTTTCTAATTCACAGCCCAAAGACATGGCAGAGACTGAGGTGGAGAGACTCTCTCGAAGGTCACCATGGTAAGTGTGTGAATTTTATTTTGTCATGGCGTATAAAAAAAAAAAACACAGGAGTCCCTGTCTTTCTCTATTTATTTTCCAAATTGGTGTTTACCCAGAAACAAAAAGCATTCATTGGCTGACACTTTTATTAAAAGTACTTAAAGTACATTCAAATTCTACACTTATCAGTAGCTCTATGGAAATTGGACCCTTGATCTCTGCTGGAGTTGCGTGCTGATTGTTTTTATAACCCTGTGCATGTTTTTGCGCTGCGAGAGAGGATGTCATGGTTGTGTGTCGACCGCTTTACAG[G/A]AACATGGCAGCCAAGAGGCCACCGCTAAAGCGCTTTGTTAGCTCTGGTACTTGGGCCGACATTGATGAGCCCACTCTGATGAATAGGTAAGGTCACGCGTGAAGAACTGTTGTGTACCTTCCGTCTTTCGCATTCATTTCATGTCAAAACCATAAATCCAGTGTGCCACGGAAAGGTCAAGTCATGTAGAGCAACAATGGAGGCTTTGAGCCAAGATGGTGGGCACTCAGTGCAGTGTAAACTTTGCACAGGTATGGATATGACACAGAATCCCACTCGGAGGAAGAGCGCAAAGAAGAGCCAGCGTCGGACAGAAGGACGAGCTTAACAGAATTAGGCATCAAAATCACCTCCTTCATAATGCCAGCTAAGATGTTAGTGTACCTACCGCCTCCGTTGTTTCTCTGCTTCAGCATTCAGGCTTTTTCTTCAACAAATCAAGGGTTTCCTGTGAATAATTTTGCAGTCTTTTGCTCTTACAGTTAAGCTGTGGAAATCGT
Associated Phenotype:
Not determined