Busch Lab

ZMP

mtrr

Ensembl ID:
ENSDARG00000045398
ZFIN ID:
ZDB-GENE-101115-3
Description:
LOC560667 protein [Source:UniProtKB/TrEMBL;Acc:Q4V8W4]
Human Orthologue:
MTRR
Human Description:
5-methyltetrahydrofolate-homocysteine methyltransferase reductase [Source:HGNC Symbol;Acc:7473]
Mouse Orthologue:
Mtrr
Mouse Description:
5-methyltetrahydrofolate-homocysteine methyltransferase reductase Gene [Source:MGI Symbol;Acc:MGI:18

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa10422 Nonsense Available for shipment Available now
sa24469 Essential Splice Site Available for shipment Available now
sa37856 Nonsense Mutation detected in F1 DNA Not yet available
sa37855 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa8432 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa10422
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066759 Nonsense 8 713 1 15
Genomic Location (Zv9):
Chromosome 24 (position 17453882)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 16760358
GRCz11 24 16904777
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAGTGTGGRTTKCAGTATGTTRCAYGACCGAAGAGGCTGTTKGTGTTGT[T/A]ATTTGCAAAAGCAAGGTGACTTTTTTNNCTCTCTCCATCATTTACGTTTTAC
Long Flanking Sequence:
AGAATTTAATCCTCTAGCTGCGCACCTCACCGCGCGGATCTGCCGGCTAGTTCTGGAAGAATCTCGGGGAGGGACGGACCAAACCAAGTTGACAATGTTAAAACATCCACATTTTTGTACATTACATTACCATTTAATCCCTAATTAAATAACAATATTAAACATTTAAGACAATTATGAAGGAGAAAAAGCAATTAACGAATCTTTAAATAATTTTTTTAAATTGAAGCATATTAATGGTTTATTCCATTCTCGCGATAACGACAACAAATAACGCGAGTGCGGGTACAGATTTATAATTCATGCAGATTGACTAACAAATAGACGTTACAAAATTGATTTGTGTATGTGCACACGTACAACTTGTGTATTTGAGAAAGGCCATGTGCTCGTCGTTGGTAACGTAATTTCCGATTACCTGTTCCTCCCGTTCATGCTTCTGACAGCACACCAGTGTGGATTTCAGTATGTTACATGACCGAAGAGGCTGTTTGTGTTGT[T/A]ATTTGCAAAAGCAAGGTGACTTTTTTCTCTCTCCATCATTTACGTTTTACATTTGTGACCGACATTTGTTTTTGAAGTGTCTTTGTGAGGTCTACATGACTTTAAAGTTAGACTTGGTGAAGCTACAGCTTGTTTTGATATCTTTTTGGATATCTCTTATAAAACTTATGCAACATTCACATGATCAGGGTTGCTTGATTTCCGTTTGCACCTGTATATTATAATGATTCTTTTTACATTACAAACGTACACAGATTAGGTCATATTTAAAGTAAATTGTTTCATTATATCATACAGTACATACGTGTAATAAACTAAAAGAACTTCTCACAATCACAAAATGTAAATACAGAGGTTCCTTTAAAAAAACGAAGCTCATAAATAAACATTTCAATGAAAAAAAAGGTTAATTGAACATAAATGATCATATGCTATGCAACCTTCTTTTGGAATTTATTTATGTTTTGAATAATATATTTTATTGAATAATAATTATTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24469
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066759 Essential Splice Site 396 713 8 15
Genomic Location (Zv9):
Chromosome 24 (position 17447003)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 16753479
GRCz11 24 16897898
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCAGTTTATTCTCACCTGGTGTTTAGAGATAAGGAGCACTCCGAAAAAA[G/A]TAATTTTGTGTTGTTATTAACCTTATTTAATGTAATAGTTGCTGTGCTGT
Long Flanking Sequence:
TTAATGTTTGGATTGGCTCAGATAGACCTGTTTGTTTATATTTTAAAAAAATCCAGTAAAATGTATCTTTTTAAAAGCGTACATTGTCTCTTCAGCAGCAGCAGGAGCAGGTTTATCAGCCTGGAGACGCTTTTGATATTCTCTGTCCAAACAGAGACAGTGAGGTTGAAGAGCTGCTGCTCAAACTGGATCTGCAAATGCAAAAGAACTGCACCGTTCAAGTTAATCTGCTTAAAAACACCAGCAAGAAAGGTATCACAACCTTTGTTGACACAATCTGTGACACCAAGAACAAACTGTCCTAGAAAAGAGATAAAATAATGTATTCTGGCCAACAAGTCAGACACCAGATTAAGATTAAACAACTTGAAACGTTGAATAAATGCATAGCAATTTTTTTTTCTTTTACAGCAGCAAAAGTTCCACTTCACATCCCACAGAATGGCTCTTTGCAGTTTATTCTCACCTGGTGTTTAGAGATAAGGAGCACTCCGAAAAAA[G/A]TAATTTTGTGTTGTTATTAACCTTATTTAATGTAATAGTTGCTGTGCTGTTGAAGTTGTGCACCTTTGAGTTAGCTCTAGCGCACTTACATTATACACAGTGCTTTTGATGGTTTATTTTGCTTTCTTGTCACTGACATACTTTGTTAGTTTAACTTCTACTGTTTTTAAAGGAATAGTTCACCCAAAACTATCTGTTATCATTTTATATTAATTTCAAAACTGAACAGACCGCATTGAGCATTTTAAGTCAACAACTCCTCTATTCAAAAGATCTAATTAAAAAAAAGAGTTTCTTTGATTAAATGACTCACAAATGATTCAGTCAGACTGATTCAGATTCAGCGAATTTTCAAATAAAAATCATATGTAGGTTAAATATGTCAGCTGTTGAAATACTGTTCACTCTATGAAGTGCATAAAGTAATTTCTATTTTTTGTTTATTATTGTCTGAATGTGGTAGATTTTATATAAAAATAAGCTTTAATTTAGTTAAATCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37856
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066759 Nonsense 572 713 12 15
Genomic Location (Zv9):
Chromosome 24 (position 17435324)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 16741800
GRCz11 24 16886219
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATGGTTGGACCTGGGACTGGTGTTGCACCTTTTATTGGATTTCTCCAA[C/T]AGAGGTACGTTCAGGAGTTTTTTTTAAACTATGCTTTTTACCCCCTTCAC
Long Flanking Sequence:
TATATATATATATATATATATATATATATATATATATATATATATATATTAGTTTAACTTTTTTGTGAAATAAAATGTAGAATCAAGGCAAGGCAAGTTTATTTATATAGCACATTTCATAAAATTGAATAAAATAATTTTTAAAAAATCGATAAAAGGGGACAAAAGAAACGCTTAATGTCTTTTCTTTCCATTAGTCTGAAAACAACAACTACAAAACACTTTATTAGAAGTCAAAAACCCAACATCTCAAAATAGACAATGTTTGTTTTTGTAAAAGAAAATAGTTTCTGCCTACAACCTTAAATGGATGTTATGTGGGGGATTTGAGACTATAGATGTCCCATCTGCACTTAAAATTGATTGTATCTAAATGTCACATTCAGGTACATGTCAGAGCTCGTCCCAGCAGCACCTTCCACTTACCATCCGACCCCTGTGTTCCTGTAGTCATGGTTGGACCTGGGACTGGTGTTGCACCTTTTATTGGATTTCTCCAA[C/T]AGAGGTACGTTCAGGAGTTTTTTTTAAACTATGCTTTTTACCCCCTTCACCCTTTTGTTTTGTTGACTCTGTAACTGTATTATTTTCTTAATGTTTTATTTATTTATTGTAGTTGCCAGGATATTTAATAGTCATTGTTGTGCAATGGGATAACATTTTTGCACAGATATCAAAATCGGGCCTGATAAAACAATAAGCGGAAAAATTATGTTAATGTAACGGCCATTAAGGTAACTTGAAAATGCTAACCAATCACTGCTAAATGCTACTGAAAGTAATGATCAAATTCTGAAACAAACACACAAAATGAGTAATTATTGTGTTAATGAAAATCAAGTAGACGAGTATAAAAAAAGTAGACATTGAATCATAAATTCACCTTATTCGTTTAAAGGATTTGTTCATTTATTCAGCAATGAAGTAAAGCACTCCTTACTTGAATGGCATTGAATCATTGGCTCACTCAGTTAATTCAATACAACTGATTCAGTCAGAAAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37855
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066759 Essential Splice Site 666 713 14 15
Genomic Location (Zv9):
Chromosome 24 (position 17408988)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 16715464
GRCz11 24 16859883
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTTGCCAAAATTCTCCTGGAAGACAAAGGCTGCCTTTATGTCTGTGGG[T/C]GGGTACAAAAACACATTTTTAGGCTTTGTTTAACAATCATTAGCCCCTTT
Long Flanking Sequence:
AAAGCAGCCAAACTTGTGTGAGGAGCTAGAAAATAAAAGCTGCTACAGAAGCAATTTACACCAATAGCCTTGAGGTTTTTATAAACTCCTTGCCAGATGGATGAGGGAGACGAAAATCTGAGTTTCAAATGCAACACTAATGAGCTCAATTGTTTGCTACTTCACTGCAAAATCTCAGAGAATCTAATTTGCCATTTGTACCATTCGTATGTTTTAATGCGCAAGTTTAGTTTAACCACCGCAAAAAACAACCACAGACTGATGAAATAGCAATGAAACATTGTAGTAAGAGCATCTTTTTTTTTATTTTCAGAGAGGAGCTGGAGAAATTTGTGCATAATGGGACCCTGAGCCATCTGATTGTGTGCTTCTCCAGAGATGAACCCGATGCTGCGGAAACCGTTAACAGACCAACATATGTCCAGCATAACTTGATCCTCCATGCTAAAAATCTTGCCAAAATTCTCCTGGAAGACAAAGGCTGCCTTTATGTCTGTGGG[T/C]GGGTACAAAAACACATTTTTAGGCTTTGTTTAACAATCATTAGCCCCTTTTACGCATACAGTAGTCAACATTTGAAATAAATTACCAACTTTCATCAAAGTTGTCCTAAATTAATTGAATAACACCAGAGCTGGACTGGGACGAAAAAAAAAAAAATGGCTCTGGCATTTTGGGCCAGAGCGGCCCACTACATACAGTTAAAATGCTACCCATCTGTACACGCCCTTGAATATGTTTACCAACTTCTAATCTGCAAAAGCACAAAAGCCATATATAGAAAAACAGTGAGAGTTGACTAATTACAAACAAACAAAAAAAAGTATTATAACAATAAAATGATAATCCACACTGGATGTCTATCTTTTATGTTTTGAACGAGCCTATATTAAACAACAAAAACTGCCTGCTGATGCACACAGTTAATGTTGATTAACAAAATAAAATAATAAAAGCAAAATATCAGAGACAAAATTTTAATTTAATTCAACAGTGAAACACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8432
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000066759 Nonsense 703 713 15 15
Genomic Location (Zv9):
Chromosome 24 (position 17405146)
Other Location(s):
Assembly Chromosome Position
GRCz10 24 16711622
GRCz11 24 16856041
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACTTCAGCTTGATAAACTRGATGCAATGAAGATAGTGGCAGGACTTCGC[G/T]AGGACAAGCGGTATCTACAGGACATCTGGAGTTGAGAAAGCACACATAAA
Long Flanking Sequence:
AGAGTTGTTCACAATACCTTTCCAAAAAGACAAAAGCTGCTGCAGGAATGTGGATGTTTCAAATAAATATTAAACCTTCAACATACAAGAAACCCCACAAAAAACAGTTACATGTTAACAAATACAAACACAGCCACTTAAACTTTTTTGGGGGGGTTAGAATGTCAGAATTTACCATTATTTTGAAGGATGTGTGAGTGGTGCTTTCCAGAAACATTATGGAATGTCCTTGCCTGTGTAAATAGTAGATTTAAAAAGAAAAATACCAGTAAAGTTTTTGATTGTCATTTTACTGAGATGTACTGGTATTACTGTGTGAAAGGGGCTTTTGTTCGGTTGCTCTGCCACATTTTGTTCACCTGAAATTAAACTTTATCTTATGATTTTACAGGGATGCTAAGAACATGGCAAAGGACGTGAATGACACTTTACTGGAGATCATTGGAAACGAACTTCAGCTTGATAAACTGGATGCAATGAAGATAGTGGCAGGACTTCGC[G/T]AGGACAAGCGGTATCTACAGGACATCTGGAGTTGAGAAAGCACACATAAATTACACGAACAAACGGCATCACATTCACAGACAGATGTGCAAGCTACTTTTTTGCTCACATCTGTGACACAGGTGCCATTTAGTGATAGTCAAGCTCATTAACAACCTGCTTTTCAATATTTTTTCTCTTCTTTTCAAGTATTTAGAGAATTATCTGAGGCTCGATATGGTCGGATTAGATATGTTTGGTGGAAGTGTTTTAACTGTGCCTTTTATGCAATTATTAAAGAGGAGCACTGCATGACTGTTTCATTCTTTGAAGATCGTTTCTGTAGAGTTTAGATGCAGCTGAGGTAAAATATGCATAATGCATCAGACTCCGCAGCCAGGAGGACGCTAGACACGAGAAACCAAAACATGACAGACTGGATGAGAAAACTGTCAAAAGCTGCCAAATTGAGGATCATCTGCAGCATTTCTGGGTTCTCCAGCTCTGACTATTGTTTTTTT
Associated Phenotype:
Not determined