Busch Lab

ZMP

POLQ

Ensembl ID:
ENSDARG00000044622
Description:
polymerase (DNA directed), theta [Source:HGNC Symbol;Acc:9186]
Human Orthologue:
POLQ
Human Description:
polymerase (DNA directed), theta [Source:HGNC Symbol;Acc:9186]
Mouse Orthologue:
Polq
Mouse Description:
polymerase (DNA directed), theta Gene [Source:MGI Symbol;Acc:MGI:2155399]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa13096 Nonsense Available for shipment Available now
sa15872 Nonsense Available for shipment Available now
sa13310 Nonsense Available for shipment Available now
sa37302 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa13096
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065556 Nonsense 345 2576 5 32
Genomic Location (Zv9):
Chromosome 21 (position 21981922)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22830335
GRCz11 21 22866940
KASP Assay ID:
2261-5601.1 (used for ordering genotyping assays)
KASP Sequence:
AAACATTGGTTTCTGAGTTGCTGAWCTTGAAGAGAGTGCTGGAAACAAGA[C/T]AGAAAGCCATGTTCATTCTTCCGTTCGTGTCTGTGGCGAGAGAGAAGATG
Long Flanking Sequence:
TATTATGCACTTTTTTATAAGATGTAAAACAAGTCTCTGATGTGCCTAAATATAAGAAGTGTCTTAGAAGAATATAGTCTATGGAGACTATGGTGTTCGGTGTTCATTTATGCATCTTAAAACTCATTTATAATCCTATTAGTCGCTGACATTATCTTTACCAGCTATGGTGAAAAAACTAATGGTAGATGGCTGCTTCTCACTCTGGGATGTCTATGATGATGAGAGAGAGATTGTCACTAATGGGTAGAGCTTTCCCCCTGATGATATGTACAAAGGGAGAATTGATTGACATTTTTTTATTAAAGAAAATAGAGTCAACTTATACCATTATAGGCTGGCTATATTCACATACTGTTGCCACACAACTGTGTTTATAAAAGGGATTTTTTGCATAATAGGTCCCTTTAAAGGTAACGTTTTCTCTTTTAGCTCCAACCAGTGCAGGAAAAACATTGGTTTCTGAGTTGCTGATCTTGAAGAGAGTGCTGGAAACAAGA[C/T]AGAAAGCCATGTTCATTCTTCCGTTCGTGTCTGTGGCGAGAGAGAAGATGTTTTATCTACAGGTTGGTTATTATACAACAATTATACATAAACACAAAAATTTACCTTAAAAATCTTAAAAAATAAAAAATATTTAAGGTAAAACACCTGTCAATACACATCTTGGAATTTTACTAATATATATTATACTTACTATTTTTTACTCAGAATGTATTTCAGGAGGCAGGGATCAGGGTGGAGGGATATATGGGGAGCACTTCAGCAGCTGGTGGGTTTTCAGCACTAGATGTCGCTGTTTGCACAATAGAGAAAGCTAACGGACTCGTCAACAGACTCATTGAAGAAGATAAACTGGATTTACTTGGTAAAAATAACAAAAAATATTTGGCCTCTTATAATGTTGTGACAGGTACGTTTAAAAAACTAAATTCTCTCTCAAACTGCAGGAACTGTTGTAGTTGATGAGCTGCACATGGTTGGGGACTCTGGTCGTGGATATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15872
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065556 Nonsense 445 2576 7 32
Genomic Location (Zv9):
Chromosome 21 (position 21981395)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22829808
GRCz11 21 22866413
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGGGGACTCTGGTCGTGGAKATCTGTTAGAGCTTTTGCTTACTAAAATA[C/T]GATACATTGCCCAAAAAACTGCAACASGGTATGTTAWAAYGGAATTTTAA
Long Flanking Sequence:
GTGTCTGTGGCGAGAGAGAAGATGTTTTATCTACAGGTTGGTTATTATACAACAATTATACATAAACACAAAAATTTACCTTAAAAATCTTAAAAAATAAAAAATATTTAAGGTAAAACACCTGTCAATACACATCTTGGAATTTTACTAATATATATTATACTTACTATTTTTTACTCAGAATGTATTTCAGGAGGCAGGGATCAGGGTGGAGGGATATATGGGGAGCACTTCAGCAGCTGGTGGGTTTTCAGCACTAGATGTCGCTGTTTGCACAATAGAGAAAGCTAACGGACTCGTCAACAGACTCATTGAAGAAGATAAACTGGATTTACTTGGTAAAAATAACAAAAAATATTTGGCCTCTTATAATGTTGTGACAGGTACGTTTAAAAAACTAAATTCTCTCTCAAACTGCAGGAACTGTTGTAGTTGATGAGCTGCACATGGTTGGGGACTCTGGTCGTGGATATCTGTTAGAGCTTTTGCTTACTAAAATA[C/T]GATACATTGCCCAAAAAACTGCAACACGGTATGTTAAAATGGAATTTTAAAATAAATTATGTTTATTATGCATGGTGGAAGTGAACATCTTTTCTATTTAAAGAAACTCTGGTCAGAGTACCTCTACTGGTGTGCAGATTATTGGTATGAGTGCCACGCTGCCAAACTTGGATCTTCTTGCCCGCTGGTTGAGTGCTGAGCTGTATAGTACGAACTATCGCCCAGTGCCACTGATGGAGTGGGTCAAGATTGGCACAAATATTTATGACGGATCTCTGAATTTGGTCAGACAGTTCACTCCAGCTCTTCCCATTAAGGTCTGAGACATATTTTTTGGTTAATTAAATAAAAAAAAAAATTCCCCATGACATACTAAACTTGCTAATGTTTACATATCCAATTTCCTTTAGGGAGACGATGATCACATTGTCAGCCTCTGCTTTGAGACCGTACAGGACGGACACTCTGCACTGCTGTTTTGCCCTTCGAAGAACTGGTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13310
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065556 Nonsense 859 2576 15 32
Genomic Location (Zv9):
Chromosome 21 (position 21977489)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22825902
GRCz11 21 22862507
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TATATGGGTTTTTAACAGTCATGTCACWTATTTAAGATAACCCCTGTGTA[T/A]GTGGACTGGACRACAATAGACTGGTATCAGTTTTTCTGTCTTTGGGAGCA
Long Flanking Sequence:
TGTATGCAGCTTGCACTCTGCTGGCGGCCAGTATAGCAGCTGAAGAAGTTCATCAGGATGGAAGCGAGTCAGAAGCTCGAAATAAAGGTGCTATTGAAGCCTGCATCGAGTGGCTGATGGACAATGAGTTCATCCATATACAGAAAGAAGGAGATGGTAAGATGCCAAAAGACAAATATATAGCAGTAAAAACCTACAGTAGCAGTCATCTTCTGTGACGTGATGATAACATTTTGATAATTGTGTGTCTATTAGTGGAGAGGTACTGTCCTACACATTTGGGTTCTGCGACGTTGTCTTCCTCTTTATCACCTCCGGAAGCATTGGGGATTTTTGCAGATCTTCAGAGAGCAATGAAAGGATTTGTGCTGGAAAATGATCTCCATATCCTTTACCAGGTAGACAGAACAAACTGTTAATCAATTTTAAATGTGTTTTTTTTTGTTTTCATATATGGGTTTTTAACAGTCATGTCACATATTTAAGATAACCCCTGTGTA[T/A]GTGGACTGGACGACAATAGACTGGTATCAGTTTTTCTGTCTTTGGGAGCAACTACCATCGGCAATGAAGCGGGTGGCTGAGATGGTCGGCATACAGGAAGGTTTCCTGGCTCGTTCTGTTGGTGGCAAATTAATTGCAAAAACCGAGAAGCAACGTAGGCAGATGGCCATTCACAAACGGTACAGTGTGTTAGTTATTTAGAATGCTTCTTTTAATTTGCTTTCAAGTAGCAGCTTGTTGATGTGTATCTTTTTTCATCCTGAAGCTTTTTCACAACGTTAGTTCTTCTTGACTTGGTAAGCGAAGAGCCTCTTGGAGCTGTTGCAAAGAAGTATGGCTGTAGCCGAGGACAGCTTCAGTCACTTCAGCAGTCTGCTTCCACTTATGCAGGTACACTGATATCTCGTCATGCATCTAATGAAACTTGTTTCTCACTTGGATTGTAAAAAGCTATTTACATAAGATAAAATAATACGTACACATATATACATACAGTGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37302
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000065556 Nonsense 1079 2576 18 32
Genomic Location (Zv9):
Chromosome 21 (position 21975473)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 22823886
GRCz11 21 22860491
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATCTGGGTCAGTGGGAAAAAGGCATTGACTGAAAGAGAAGCTGCCCAG[C/T]AGATCGTGGCTGAAGCCCAGCTGCTCCTCCAGAAAGATCTGGCTCTTCTA
Long Flanking Sequence:
CAGTTCCAGAGTCGTCTCAGTTTTGGAGTCCAGAGGGAGTTGTGTGATCTAGTTCGAATCTCTTTACTAACTGCCCAGAGAGCACGAACACTTTACAGCTCTGGGTTTGTCACGGTAGCAGAGTTGGCCAGAGCTGATGTTACAGAGGTGGAGAAGGCCTTAAGGAAAGCTATTCCTTTTAAAAGGTAATGAAAAGGGTTACTTGATGATATTTTAATGTTTGAATTGCCTTTATTTGTTGCAAAATATATGCATTTAAGGGTGCAAGACTGCTAAAATTATAGAATTTTAAAATATCATTATTCATCAGATTATTGCCTAAAGTGTAGTTTTAATATTGATTCATTAATAGATTACATCAAGTCATTCATTGATCATTTCAATCTTGCAGCTCCAGACAGGCAGTAGATGAGAGCGAGGTGGAGGCTCAAGAACGCAAGAGTATGCGCTGTATCTGGGTCAGTGGGAAAAAGGCATTGACTGAAAGAGAAGCTGCCCAG[C/T]AGATCGTGGCTGAAGCCCAGCTGCTCCTCCAGAAAGATCTGGCTCTTCTAGGGGTGGAGTGGAACCCAGCTTGCCTCCCAGCAAAGACTCAGCCAGATAACAGTTCAAACACAGAACCACGGTCCATGTCAGGAGGCACAGAACATGAAGGGGGCCAAGACTTAATGTTAAATGTGACTGAAGAGAAGTTACTGCTGGAAAATAATTCTAACAATAATTCACACCCCCCTTTGAGGCCATTAGAATCCACTACCAATTTAGAAAAAACCATGGACGTTGACTCGGGTGTATCATCTGCTGAATGCCAACCTGATAAGAAATGTGAACTGCAATCAAGTGTACTTCATAAAGTTCTCAAATCTATCAATGCAAAAGACAAGGGCTGTGATAATAACCAGACAGTTGAATCATCATCTGAATCACTTCAGAGGCGAAATTCATGTCTTAATACCTGCATCTCTGGCAATGACCAACACTGTGTTAGTCCAGTTTCAAAACGC
Associated Phenotype:
Not determined