ZMP
vars
Ensembl ID:
ZFIN IDs:
Description:
Valyl-tRNA synthetase [Source:UniProtKB/TrEMBL;Acc:Q8JHH7]
Human Orthologue:
VARS
Human Description:
valyl-tRNA synthetase [Source:HGNC Symbol;Acc:12651]
Mouse Orthologue:
Vars
Mouse Description:
valyl-tRNA synthetase Gene [Source:MGI Symbol;Acc:MGI:90675]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa44838 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa42669 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa22767 | Splice Site, Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa44838
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000004832 | Essential Splice Site | 295 | 425 | 6 | 9 |
| ENSDART00000112095 | Essential Splice Site | 285 | 1264 | 5 | 30 |
Genomic Location (Zv9):
Chromosome 16 (position 12048475)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 10548141 |
| GRCz11 | 16 | 10439043 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTGGGTGTGATCACCTACAATGTCTCCACACCACCTGGAGAGAAAAAAG[G/A]TGGGCATTTGCTTCTGATACAGTCATCATATTTTATGTTATTTAATTTCT
Long Flanking Sequence:
TCTCACTATGTGAGAAAATGGTGCCTGTGACCCCCAAACCCAACACTGCTTCCAATGTCACAGTAACTGCTGCTGCTGCTGCTAAACCAGACAGCGGACCTGCTAATGGTAAAAATCTCAATGTATATAGATTTTGTATTGTAACATTTTAAACGTGTTTTAAGAACATCAGCTTAAATGCTCTTGTCACTTTAAATAGATCAGGTTTTCCTGTTGGTTTTGTTATTCCTAGGTCCTCCTAAGACAGAAGCTCAACTGAAGAAAGAGGCCAAGAAGCGAGAAAAGATGGAGAAGTTTCAACAGAAGAAAGACATGGAGGAGAAGAAGAAAATGCAGCCTCAGACTGAGGTAGAGTGATCATTTCAGCATCCTTTTTACTTATTGACACTGAGATAAACAGACAGCTGATCATCTCCTTCAACAGAAAAAGGCCAAACCAGAGAAGAAGGAACTGGGTGTGATCACCTACAATGTCTCCACACCACCTGGAGAGAAAAAAG[G/A]TGGGCATTTGCTTCTGATACAGTCATCATATTTTATGTTATTTAATTTCTATTTTAGTAGCATATTATCAGGCACTGTTTAGTTACTTGTGTGTCTCTCCATATGGGTTTCAGATGTCCTGAGTCCTCTGCCTGATTCATACAGTCCTCAGTATGTGGAAGCGGCCTGGTACTCCTGGTGGGAGAAACAAGGATTTTTCAAGCCTGAATATGGGGTACGACTAGAAAATATTTTTTAAAATAATATGATTATTTATTTATTTATTTACATGTGAATGGTTTGTGAGCACAATTAGGTGCACACAGCATGCCATATTATCTGATAATAATCCCAAAAAGCAACTGACTGAGTAAAGCCACATAAAACAATACAAAAATATGATGCATATGTTGAGTTCAGCAGCTAATCAGCCGGAATCAGCTGAGGTGAAGTGACGGCGACCAGTGAGACCTAGCTGTCACTCAAGTGGCCCCGCACTTAATTACTCAGACTTAATAAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa42669
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000004832 | None | None | 425 | None | 9 |
| ENSDART00000112095 | Nonsense | 447 | 1264 | 10 | 30 |
Genomic Location (Zv9):
Chromosome 16 (position 12053437)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 10553103 |
| GRCz11 | 16 | 10444005 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAGTCTATTAATAATCATGCATAATATCGTCTGTTTGCAGAAACTGT[C/A]ATTTGCGGTTCAGGAGGCGTTTATACGCATGCATGAGGAGGGAGTGATCT
Long Flanking Sequence:
TTAAGTTATTTTTTTACTGAAAATATCTAAATTGTGTCCTCAGTGTCGGGGAATAACACCTATTTTGTGACTTGATCTTGCCCAGTTAGAGCAGGCAAGAACCAAGAACACCATTTCTCAGTTATTATATTAAAGTCTTTAAGCTTTTATAAATATTTATTTTGTCAGTGTACTTATTATACCTCAAATCTCCAAAAATATTCATCTAGTTGATGTGTTTGACTTTTTCTGACAATAAAAGAGTAATTGAAATCAACAGTGACTGTCTCGTTTGTACAACATTCACTAAGGATCTGCCGTAATATCTGCATAAACAAAATAGAGACTTGGCATTGACTTAATTTATGTAAACTAATATGAAAGCCAGCACAAGGACTTCAGACAGAGGATCTGATTGTTTTGAACAAGCTTTGGATGTGTATGTGCATGCAAGTGTCATTATTTAATAATGAAAAGTCTATTAATAATCATGCATAATATCGTCTGTTTGCAGAAACTGT[C/A]ATTTGCGGTTCAGGAGGCGTTTATACGCATGCATGAGGAGGGAGTGATCTACAGGAGCAAGAGACTCGTCAACTGGTCCTGCACACTCAACTCTGCCATCTCTGACATTGAGGTACATTCATATCTGAATAAATAGATGGATAATGTACAATCTATCAGCTCATTGTCACTAACTCCTATCTAAGAAAAACATGGAAAAATGTGTCCTACTATGCTTTTTACGCTAACAGCTTCCTTTTCTCTGTAATGTTGCTGTTTGAGCATGATAACTCAAGTTGAAGTGTTGAGTTATGTTAACTGTGTGAATTTGACATAACTATGAAGTTTTATAGTTGGTACATATAGGTTGTTAGCAATCACATGGTTCTGGTGACATGTGCAATTCAGATGGAGGGCAGGAAGTAAGAAAACTGAATGGAAAACATAAGGGGATGTCTGTATTTTTGTGATTCATAGCATACTTCAAAGGAGATAAAAATAGAAAGTAAGCACATACAGTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa22767
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Splice Site, Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000004832 | None | None | 425 | None | 9 |
| ENSDART00000112095 | Splice Site, Nonsense | 903 | 1264 | 23 | 30 |
Genomic Location (Zv9):
Chromosome 16 (position 12072699)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 16 | 10572365 |
| GRCz11 | 16 | 10463267 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGCTGCTGTGCGTTCCTGTAACATGTTGTGTCTGTGTTTGATCTGTAG[A/T]AATCCGACTATCCCACTGGAATTCCAGAATGTGGGACTGATGCGCTTAGA
Long Flanking Sequence:
TCTAGGATTCATCACACTGTGTGGGCCTAATGTCCCCACTAATATAGCAATAGCAGTCATTTTAGATTTTTTTTTTCACTATGCAGTAAATGGCTCATGGGGACCAAAAAAAATATATATATTACTGGTATTGCTATACTTATGGGAACATTTGTTCCACACAATTTGATGAAAACATGGACCAAATACACACACATTAAATTATCAGATTTTGTGTGGGTCTACGGATGGGGATGAGGATAGAATGTAAAATTTGTACATGTAAAATAATACTTCAAAACCGGTGTGTGTGTGTGTTTGTGTTTGTGTGTATGTGTGTGTGTGTGTAGGGTCTTTATGCTCAGCTTGCAGACAGTAATCTGGATCCTCTGGAGATTGAGAAAGCCAAACAGGGACAGGTATAATCCATATTCTATGATCTCTTGTAATGTTTTGATATTGTGCCTTTTAGCTGCTGCTGTGCGTTCCTGTAACATGTTGTGTCTGTGTTTGATCTGTAG[A/T]AATCCGACTATCCCACTGGAATTCCAGAATGTGGGACTGATGCGCTTAGATTTGCTCTGTGTGCATACACCAGTCAAGGTAAAAAAAAACACAATCAAAAGCTTGTATTCCCTCACATCTGTTAGTGTAGTACCAAATAGCAGCTTTTGACACCGTGTCCCTGTAGTTCTTTTGTAAATATGTGTAGTAATAAAAAAATGTCAGTGTCTACATTAAAGACACTATGATAAAATGTAGGTTGTTGCTAGAGCGGATACGTTTGCAGCCGGAAGTTAACGCAAATTATTTCTATTATTTATAAAATTTCTCAATTATTGTATTCTATTAACGTCTACCCCCACCCCAACCCTAAACCCAACCGTCACAGTAATGTAAAAACTGTAGTTGTACCGAGTATTAGTTATGTTATCTATTAAATTACCCAATAAAATGTATTTTTTAACGCCTACCCCCACCCCAACCCTAAACCCAACCCTCACAGTACTGTAAAAACATTCATT
Associated Phenotype:
Not determined