ZMP
si:dkey-273o13.5
Ensembl ID:
ZFIN ID:
Description:
ribosomal protein S6 kinase alpha-4 [Source:RefSeq peptide;Acc:NP_001119875]
Human Orthologue:
RPS6KA4
Human Description:
ribosomal protein S6 kinase, 90kDa, polypeptide 4 [Source:HGNC Symbol;Acc:10433]
Mouse Orthologue:
Rps6ka4
Mouse Description:
ribosomal protein S6 kinase, polypeptide 4 Gene [Source:MGI Symbol;Acc:MGI:1930076]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa10999 | Nonsense | Available for shipment | Available now |
| sa38527 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa20581 | Essential Splice Site | Available for shipment | Available now |
| sa40597 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa38526 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa10999
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065262 | Nonsense | 112 | 745 | 4 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 70104238)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 66430396 |
| GRCz11 | 5 | 67108765 |
KASP Assay ID:
2259-6837.1 (used for ordering genotyping assays)
KASP Sequence:
ACACACCTCTATCAGAGAGATCAKTTCTCAGAGGATGAGGTGAGGATCTA[T/A]GTGGGGGAGATTATTCTGGCTCTGGAGCATCTGCATAAGGTACTGCTGCM
Long Flanking Sequence:
TCCTAATGAAAAAATTAAAAATCAAGGCATGATCATATTTTATTTTGATAAAATAGGCGTAATCTAGAGGCCTTTGCCTTTCATATAAGCCACTTCTGATTCTAAATGATCAACTAAAAGTCAAGTTATTATTTGTTGTTTCTAAGACTTGGATGGATGACAAGACTCTTCATGTAGTGTATATATGTATATGTGTGTATTTTTATTAATTAATTCATTTGTAAAAAATAACAGTTGTCTAATTATGTATACAGTTATTGTGATGTAAAATAACTCCTCATATAAAATTACTATTGTGATGTAAAAATCCTCCTATGATGCGAGACATTGGTCACATCAGCCACCCCAAGTTTCAAGCTCTTTGTCTTTTAGTAAATTGCTGTTTTTTTGGGATAATGTGCTGAGTGCATGTTTGTTTCTGAAGACTATGTGAGCGGAGGAGAGATGTTCACACACCTCTATCAGAGAGATCATTTCTCAGAGGATGAGGTGAGGATCTA[T/A]GTGGGGGAGATTATTCTGGCTCTGGAGCATCTGCATAAGGTACTGCTGCCTGGTTTTTATTGATACATAGATATATATGCAAAGTTAGGGAAATAAGTTCATTTATATAAATATTAAGACTGTTTGTGTTTGTATAACCCTACTTGGTTTTGTGTTTTCAGCTTGGCATTGTGTACCGAGACATTAAGCTGGAGAACATTTTATTGGACAGTGATGGTCATGTGGTTTTGACAGACTTTGGGCTGAGTAAGGAGTTTCTGGAGGAGGAGGTGGGGAAAATAAAAGCTATTAAAAGTTACCAATACAATATATTTTGTATGTTTTTGGCCAAAATTGGTGTTCAGCCAAGAACCATTCAAAAGGAGTTCTTTATTTAGGCATAATATATTTATATTTAAGCTTGTAGGGGCATTAAAACAAGTCCCATTTGGTCATTGCTTTTGGCCTTCTAGATTTTTTTCTTGGTTCCGTGTTGTGTTGTAAACCTTTACGCATTTCTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38527
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065262 | Nonsense | 140 | 745 | 5 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 70104033)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 66430191 |
| GRCz11 | 5 | 67108560 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTCAGCTTGGCATTGTGTACCGAGACATTAAGCTGGAGAACATTTTAT[T/A]GGACAGTGATGGTCATGTGGTTTTGACAGACTTTGGGCTGAGTAAGGAGT
Long Flanking Sequence:
TTAATTAATTCATTTGTAAAAAATAACAGTTGTCTAATTATGTATACAGTTATTGTGATGTAAAATAACTCCTCATATAAAATTACTATTGTGATGTAAAAATCCTCCTATGATGCGAGACATTGGTCACATCAGCCACCCCAAGTTTCAAGCTCTTTGTCTTTTAGTAAATTGCTGTTTTTTTGGGATAATGTGCTGAGTGCATGTTTGTTTCTGAAGACTATGTGAGCGGAGGAGAGATGTTCACACACCTCTATCAGAGAGATCATTTCTCAGAGGATGAGGTGAGGATCTATGTGGGGGAGATTATTCTGGCTCTGGAGCATCTGCATAAGGTACTGCTGCCTGGTTTTTATTGATACATAGATATATATGCAAAGTTAGGGAAATAAGTTCATTTATATAAATATTAAGACTGTTTGTGTTTGTATAACCCTACTTGGTTTTGTGTTTTCAGCTTGGCATTGTGTACCGAGACATTAAGCTGGAGAACATTTTAT[T/A]GGACAGTGATGGTCATGTGGTTTTGACAGACTTTGGGCTGAGTAAGGAGTTTCTGGAGGAGGAGGTGGGGAAAATAAAAGCTATTAAAAGTTACCAATACAATATATTTTGTATGTTTTTGGCCAAAATTGGTGTTCAGCCAAGAACCATTCAAAAGGAGTTCTTTATTTAGGCATAATATATTTATATTTAAGCTTGTAGGGGCATTAAAACAAGTCCCATTTGGTCATTGCTTTTGGCCTTCTAGATTTTTTTCTTGGTTCCGTGTTGTGTTGTAAACCTTTACGCATTTCTCATGCTTTGTTTATGTGTAGAAAGAGAGGACTTATTCATTCTGTGGCACTATAGAATACATGGCACCTGAGATTATCAGAGGGAAGTCTGGCCATGGCAAGGTAAGAAAATTAAATAACAAGCATTTTTTATTTCCCCATCAAAATGTAATGGAAAAAATGTGATCGGAAAAAGGATTATCTAATTTTTTTTCTTGTATTCTGACT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa20581
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065262 | Essential Splice Site | 369 | 745 | 10 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 70091805)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 66417963 |
| GRCz11 | 5 | 67096332 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGTTGACCGGCCTGGTTCTGCTACAGTCCAGCGTAGTGCAATGCTGAAG[G/A]TGAACAACTGCTTCTGTAAAAATGATTAAATAAATGAAAAAAGGTTAAAG
Long Flanking Sequence:
CCACTTGAGAGAGAGATGAAATAGTGAGCAAATTTTCATTTTTGGGTGATATTAATTTTAAAGACTATTAATGTGACAAATAACTAAATATTTTATTTTAAATAAATGTTTTTATTTGTTTAATCTAGACTCCTGAAAAGGATTTCAAAATATGAAACGCAAAAAACAAACAAACAAACAAACTACTGAGCACCAATAGTAATTTATTTTGAACCGATCAGCAATTAGAATGTAGTAAGAATGAATTTTATTTTGATCAAATAAATGCAGCTTTTTGACTGGATACTACCTTCATTTTTGTATATATTTTTCCCCCCAGCATGTCCCCTTTTGGCAAAAGTAAACTCTTTTATTCTGTCTTTTCTTCCTCTCAGGGCTACTCTTTCGTGGCTCCTTCGATCTTATTCAATAAGAATGTGGTGATGGCGGATGTTTTGGATGCTCATGTTAACGTTGACCGGCCTGGTTCTGCTACAGTCCAGCGTAGTGCAATGCTGAAG[G/A]TGAACAACTGCTTCTGTAAAAATGATTAAATAAATGAAAAAAGGTTAAAGTTAGAATTATTAGCCCCCCTTTGAATTTTATTTTTAAAATATTTCCAAATAATGTTTAACAGAGCAAGGTTTTACAGTATGTCTGATAATATTTTTTTCTTCTGGAGAAAGTCCTATTTGTTTTATTTTATTTATTTTTTTTAAACACCATTTTATGGACAACATTATTAGCCCCTTTAAGCTATATATTTTTTGGTAGTCTACAGAACAAACCATCGTTAAACAGTAACTTGCCTAATAACCCTAACCTGCCTAGTTATTGCTGCCTAGTTATTATATACCTGCCCTAGAAATTGGGGAAAAAAATAAACGGGCTAATAATTCTGACTTGAACTTTATATATATATATATATATATATATATACTATATATATATATATACTCATTTTATACTAGAAAAAAGGTTAAAGAGTGATGTTTTTTCTCTCTTTTTTTCAGGAGTCTCAGTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40597
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065262 | Nonsense | 559 | 745 | 14 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 70082398)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 66408556 |
| GRCz11 | 5 | 67086925 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGTACGCAGCGCCTGAGCTCTTCCACAGCTCGGGATATGACCAGGCGTG[T/A]GACCTCTGGAGCCTTGGGGTCATATTGGTAAGTGTGTGTGTATCAAGGTT
Long Flanking Sequence:
GTGCTAGGAAATTTAAATGTGGCTTCTTACATGCAGGTAAAAGCACTGAGGAAAAGTGCACTAGACTGCCGACATTAATCTTCATCAGGCAACTTTTATTCATTTTTTTATTTATTTATTTTCGCAAAAATGAAATCTTTCAGGTGTAGTTTAGAGCAGCTGTCTCATGATGCGATACGCATTGCCTGTTTCAATACATTGTGATGCTTCATAATTGGATCAAGGGTGCTAAATATGCTCATGAAGTCAAATGGCTGTAACGCAGAACCTCTTGTGGTTTATTATGTTAATGCATTGCGGTGTTGTTGTCTTTTTCACCTCCACCTGCAGAACGTGCTGTTCGCTGATGAGTCGGATGAGTCTGTGTTGAAGGTTATTGACTTTGGCTTTGCACGGTTGTTTCCGGCGGGGAGCGGGAGTGCCCCTCTGCAGACCCCCTGCTTTACATTGCAGTACGCAGCGCCTGAGCTCTTCCACAGCTCGGGATATGACCAGGCGTG[T/A]GACCTCTGGAGCCTTGGGGTCATATTGGTAAGTGTGTGTGTATCAAGGTTATTTTAGTAAAGGATGACTAAAACTATTGGTCCGTATCTGTCAGTTGACAAAGTGTTGGTGAGTTGTCTAAAACTGTTAGTCATTGACTAAAACTCTTGGTGAGTTGACAAACTATTGGTTAGTTGATAAAATAGTTTCGGCCAATTGACTAGAACTTGGTCAGCTGACTAAAACTTTTGATCAGTTGACTAAAACTATTGGTCAGTCAACTAAAACTGTTGGACAGTTGACTAAAACTTGGTCAGTTGAATAAAACTTGGTCAGTTGGTTAAAACTATTGGTCAGTTGACAAACTATTGGTCAGTCGACTAAAACTGTTGGACAATTGACTAAAACTATTGGTCAGTTGAATAAAACTTGGTCAGTTGAATAAAACTGTTGGTCAGTCGACTAAAACTATTGATCAGTTTACTAAAACTATTGGTCAGTTGACTAAAACTGTTGGTCAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa38526
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065262 | Essential Splice Site | 569 | 745 | 15 | 17 |
Genomic Location (Zv9):
Chromosome 5 (position 70080629)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 66406787 |
| GRCz11 | 5 | 67085156 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATATATATATTTAAACAAATACTGATACAGGTAGTGTTTTTCTTCTTCTT[A/C]GTACACCATGCTCTCTGGCCAAGTTCCATTCCAGAGTGAGAAAAAAGTTA
Long Flanking Sequence:
AGTTGACTAAAACTATTGATCAGTTGACTAAAACTATTGATCAGTTGACTAAAACTATTGATCAGTTGACTAAAACTGTTGGTCAGTTGAATAAAACGGTTGGTCAGTCGACTAAAACTTTTGATCAGTTGACTAAAACTGTTGGTCAGTTGACTAAAACCTGGTCAGTTCAGCAAAACTATTGATTAGTTGACTAAAACTATTAGTCAGTCGACTAAAACTATTGGTCAGTTGATTCAAAAATTTGACCAGTTGACTAAACTTGGTCAGTTGATTAAAACCTGGTCAGTTGATTAAAACTCTTGATCACTTGACTAAAACTATCGGTCAGTCGAATAAAACTATATTAATTAAAAAAAAAAAAAAAAAAAAAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTAAACAAATACTGATACAGGTAGTGTTTTTCTTCTTCTT[A/C]GTACACCATGCTCTCTGGCCAAGTTCCATTCCAGAGTGAGAAAAAAGTTATGACATCATCGCACGCTGCCGACATCATGCACAAGATCAAAGAGGGCGATTTCTCATTGGATGGAGAAGCCTGGAAGGGCGTGTCCGAGGAGGCCAAAGATCTAGTGAGAGGTACTGATAGTTTACTTTGGTTACTGGTTTTCGCAGTGCTTATACTCTGTATATAGGTAGGTTTTTTTAGATCAAAAATATTAGATGAGTACATATTTAAATATCTAATAATGTTTATAAAGAGTTTGGGAACCATAGTTTTTTTCTAGTTAAAGGACAGTGCATTCAAATATATGAATTCATACAGCAATTATATAATCTCATGACATTGGAGTTTGTGTAAAACTGCAGATAATTTTACACCGGTAGGGATGTTACAGGCAAAATTCAATTCTGTCAGGAGGAGTGGGCCAAAATTCCTTCAAATCATTGTGAGGAGCTTGTGGAAGGATACTCAAA
Associated Phenotype:
Not determined