Busch Lab

ZMP

kars

Ensembl ID:
ENSDARG00000044220
ZFIN IDs:
ZDB-GENE-021115-8, ZDB-GENE-021115-8
Description:
lysyl-tRNA synthetase [Source:RefSeq peptide;Acc:NP_001002386]
Human Orthologue:
KARS
Human Description:
lysyl-tRNA synthetase [Source:HGNC Symbol;Acc:6215]
Mouse Orthologue:
Kars
Mouse Description:
lysyl-tRNA synthetase Gene [Source:MGI Symbol;Acc:MGI:1934754]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa694 Essential Splice Site Available for shipment Available now
sa21133 Essential Splice Site Available for shipment Available now
sa21134 Splice Site, Nonsense Available for shipment Available now
sa15144 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa694
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064924 Essential Splice Site 15 577 1 15
ENSDART00000064926 Essential Splice Site None 602 1 15
Genomic Location (Zv9):
Chromosome 7 (position 69483470)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 67206230
GRCz11 7 67429592
KASP Assay ID:
554-0602.1 (used for ordering genotyping assays)
KASP Sequence:
GAGAAGATGGCAGACGGAGCTGTGGTGGATGGAGACAAACTCAGCAAAAA[G/A]TATAGACATTTACACAATTATAGCGCTTAGGCTGCTTTTGTGCGAACTAA
Long Flanking Sequence:
NNNNTATATATATATATATATATATATATATATACCAAGCTTATGAAATTGTCTGTTGTGTTGCATTAGTAGGCTTTAATATAATTATATAAAAATCATTTAAGAATCAAGCACTAGGTTTATTAATATAGACATAAATGACCAATAATTTAGGAATAATCATTCTTGGTAACGTTAAATATACAGTTTATGGCTTCTTTTTAACATGTTTGTGTATATTTTACGGTTTCATCATATTTTAATCTGTTTTATTGTTAATCAATGACATTTTTATTGGTGTTGTTTATCTTAATATGCAAATATTTATTCAAAAAACAAACCACTTACGAGAAAAGGAAGTGATGCAACTTTAAGCAACGGAACTTTTACAGTGAAGCGTGGTCGAACATTAGCCGGTTTTATTGCTGCAGTGTTGTTTATATCTGGCTTCACTGTCCTGCTGCGAGCGTGGAGAAGATGGCAGACGGAGCTGTGGTGGATGGAGACAAACTCAGCAAAAA[G/A]TATAGACATTTACACAATTATAGCGCTTAGGCTGCTTTTGTGCGAACTAAAACCTAAGATAAGTTGGACTGTGTGCGTTGCGCGACGTTCATACTCTCTGTTGTCCTGTAAGATCCGTTGTGATGAAGTGCAACGTGGTTTGTTCTGCGTGAACGCGACTGAATGATAGCTTGTTTTGATTACGATTTATTGCGTGTAAATGGTTCTCCCTTGTCGGCATATTTCAGGATCAGTCAAAAATCTGTTTTACCTAAATTAATCTTAAAATGACACTCACGTTCTCATTTCATCCTCCATAGCGCGCCGAGAAAGCTAATGGCGTGTTCGCTTGAGACTCATTTCCGTGACCGTTAAAAATAATATTCGGCGACTATTTTACGCTGAGAATTCGTCAAATATTTGTTATCTTACCTTAAATGCGTTAAGTATGTTAATATAATCTTTTCTGCGCTTCTGTCAGTTAACGGAACTAAAGTACTTTCGATTCTGGGGGTCAGTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21133
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064924 Essential Splice Site 211 577 5 15
ENSDART00000064926 Essential Splice Site 236 602 6 15
Genomic Location (Zv9):
Chromosome 7 (position 69490361)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 67213030
GRCz11 7 67436382
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCCATGTCTTCATATGCTTCCACATCTTCACTTTGGCCTGAAAGACAAG[G/A]TAAAGCTTTGTTTTTAAATCACTTTGGAAATAATATCTCTCTTTCAGACT
Long Flanking Sequence:
TCGTAGGCCAACAATTGAAAGGACCACATAATACAAATACAACATGCTAACTTCAGTGAACTTGTTTGTTTATTTGTGTTTTTTAGGCAAATTGTGCATGTGTTGTTAGGATTTGCAGTGTGTTTTCTACATGTGTTTGCCTTGTCAGGATTTGTCAAATCAGTGAAGATGTTTTCTTAATTAGCTTTTGTTTTCTGATTCTGACATTTCTGATGAAGTGTTTTTGTTGTTTTTTTAAGTTGCAGCACGTTACGTTTTCTCGGCCACCATAGTCTTTTCATGTTATATACTTACATGACCAGTCTTTTCTTAGAAACTACACATCAGAAGAAGCGTTTGTGCACATCAACAACAAACTGAGGCGTGGAGACATCATCGGGGTCCGGGGGAACCCTGGCAAGACAAAGAAGGGCGAGTTGAGCATCATCCCAGTGGAGATGACCCTGCTGTCTCCATGTCTTCATATGCTTCCACATCTTCACTTTGGCCTGAAAGACAAG[G/A]TAAAGCTTTGTTTTTAAATCACTTTGGAAATAATATCTCTCTTTCAGACTTCTTTTTCTTTGTCTGCAACCTTTTGGGGGTGGGAGAAGCACACTTGTGTATTTTATAATATGCTGTTTAATTGCAATTCAGTAAAAATTCTTTATAGTTGTCAGTGCTAATAGCCTAGTGGTTAAGTGCGCTGACATGGAGGTGCTCACGGTGACAAAAGTTTGATTTCTGGCTCCAGGTCCTAAAATGATCCTAGTATCTGCTCTCATTACCGTTCTTTCTGTAATCTCTACTGTTCTATCCTAATAAAGGTGAAAACCCTCTGAAAATAATTAAGAAAATAGGCAAAAAAATGCATTATAGTTTAAATTTATGTAAAATGCAAGTGATTGAGTTTTAGAATACAAAACATTTAATAAAATAACTGACCTATTTTCTGTAGAAGACACTTAGAGTGCTCACACTAGGTACAGTTGCCTTGGAACTGTGCTAAAGCATGATTGTCCCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa21134
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064924 Splice Site, Nonsense 406 577 9 15
ENSDART00000064926 Splice Site, Nonsense 431 602 10 15
Genomic Location (Zv9):
Chromosome 7 (position 69497597)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 67220266
GRCz11 7 67443618
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAAGGAGTTGGGTGTGAAGTTTCCACCTCCTGACACCTATGACAGTGAC[G/T]GTATAGAAATGTTTGAAAACATATGTTTGCCATCACAAAAGGTGTGGGAA
Long Flanking Sequence:
CTACATTGTAAAAGAGCTATACAAATAAAGCTGGATTGAATTGAATTATACAGAATAGAATTTGAATGAAGTATAAAAGAAATAATTTATATTGCCATTCCTTGTCATTTTTATCTAAATGACAAGACTAAAATAATGAAACGCGAATTTGAATTAATCAGTTTAAGGCATAATGTTGGTCTCTTGTTCATCAGAAATGTAAATGTTTCAATTGATTTAGAAAATATTGCTTGATTCTGAAGTGCACAGTAAAGATTGAATTTTGTATTTGAAGATGTGTCTGAAAACACCAAGTGATGTTTTTTGTTGATGTTGTTGTTTTTACAGGAATGGTGAAGCACATTACCGGAGCTTATAAAGTGACGTATCATCCTGATGGTCCAGAGGGACAGGCCTACGAAATAGACTTCACCCCTCCCTTCAGGCGAATCAGCATGACCCAAGAGCTGGAGAAGGAGTTGGGTGTGAAGTTTCCACCTCCTGACACCTATGACAGTGAC[G/T]GTATAGAAATGTTTGAAAACATATGTTTGCCATCACAAAAGGTGTGGGAAGGTGTTTTTTTTCTGTTGCTAAAATAGTTTTGTGTGTGTTTTTGACAGAAATGCGCAAGTTCTTAGACGACCTGTGTGTTCAGAAAGAAGTTGAATGTCCTCCTCCCAGGACAACTGCTCGACTTCTTGATAAGGTATGAAGTAGGGCTGCACGATATTGGGAAAAGAAAAAAAGCTGACATTGCGATATTTAGTTTTTCTGTGATTAAATTGCGATATAAATATAACTTCAAAAGATGACTGACTCGATTTGGCAATATTTTATAAGGTTGAAATAGTGAGTAGTGCAACATGATTTGTGGTACATTCTCCATGCACATTGTGGTAATATTATCCATACACATTGTGGTAATATATTCAAAAAGGCGGCAACACCATACAAAGCTAATTCATTAGATTAAAAAAGGCTGATAAAAAGTGTGTAACGTTTCGAGCACACCGACTCTTCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15144
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064924 Essential Splice Site 406 577 9 15
ENSDART00000064926 Essential Splice Site 431 602 10 15
Genomic Location (Zv9):
Chromosome 7 (position 69497599)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 67220268
GRCz11 7 67443620
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGGAGTTGGGTGTGAARTTTCCACCTCCTGACACCTATGACAGTGACGG[T/C]AWAGNAAATGTTTGAAAACATATGTTTGCCATCACAAAAGGTGTGGGAAGG
Long Flanking Sequence:
ACATTGTAAAAGAGCTATACAAATAAAGCTGGATTGAATTGAATTATACAGAATAGAATTTGAATGAAGTATAAAAGAAATAATTTATATTGCCATTCCTTGTCATTTTTATCTAAATGACAAGACTAAAATAATGAAACGCGAATTTGAATTAATCAGTTTAAGGCATAATGTTGGTCTCTTGTTCATCAGAAATGTAAATGTTTCAATTGATTTAGAAAATATTGCTTGATTCTGAAGTGCACAGTAAAGATTGAATTTTGTATTTGAAGATGTGTCTGAAAACACCAAGTGATGTTTTTTGTTGATGTTGTTGTTTTTACAGGAATGGTGAAGCACATTACCGGAGCTTATAAAGTGACGTATCATCCTGATGGTCCAGAGGGACAGGCCTACGAAATAGACTTCACCCCTCCCTTCAGGCGAATCAGCATGACCCAAGAGCTGGAGAAGGAGTTGGGTGTGAAGTTTCCACCTCCTGACACCTATGACAGTGACGG[T/C]ATAGAAATGTTTGAAAACATATGTTTGCCATCACAAAAGGTGTGGGAAGGTGTTTTTTTTCTGTTGCTAAAATAGTTTTGTGTGTGTTTTTGACAGAAATGCGCAAGTTCTTAGACGACCTGTGTGTTCAGAAAGAAGTTGAATGTCCTCCTCCCAGGACAACTGCTCGACTTCTTGATAAGGTATGAAGTAGGGCTGCACGATATTGGGAAAAGAAAAAAAGCTGACATTGCGATATTTAGTTTTTCTGTGATTAAATTGCGATATAAATATAACTTCAAAAGATGACTGACTCGATTTGGCAATATTTTATAAGGTTGAAATAGTGAGTAGTGCAACATGATTTGTGGTACATTCTCCATGCACATTGTGGTAATATTATCCATACACATTGTGGTAATATATTCAAAAAGGCGGCAACACCATACAAAGCTAATTCATTAGATTAAAAAAGGCTGATAAAAAGTGTGTAACGTTTCGAGCACACCGACTCTTCATCA
Associated Phenotype:
Not determined