Busch Lab

ZMP

fto

Ensembl ID:
ENSDARG00000044216
ZFIN ID:
ZDB-GENE-061108-1
Description:
Fto protein [Source:UniProtKB/TrEMBL;Acc:Q568I7]
Human Orthologue:
FTO
Human Description:
fat mass and obesity associated [Source:HGNC Symbol;Acc:24678]
Mouse Orthologue:
Fto
Mouse Description:
fat mass and obesity associated Gene [Source:MGI Symbol;Acc:MGI:1347093]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa12749 Nonsense Available for shipment Available now
e37 Nonsense Confirmed mutation in F2 line Not yet available
sa34123 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa12749
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064913 Nonsense 119 568 3 9
ENSDART00000130028 Nonsense 131 579 3 10
Genomic Location (Zv9):
Chromosome 7 (position 37641209)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 36042810
GRCz11 7 36314287
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACACGTACCGTTATCTGGACACTCGTCTGTTCACCATCCCCTGGCACTG[T/A]GAAGGAGAAGAGGGCCAGAAAGATGAGAAAGGCAAACCTTGCTGTGACTC
Long Flanking Sequence:
ATTATATTATATTATATTATATTATATTATATTATACTAATGTTATATTATAGTAATATATTATATTATATTATATTATATTATATTATATTATATTATATTATATTATTTTTTGTAGTTTTCTGTTTTAGTAAATAGATTATACAGTTTGAACAGTACAAAAACCAGTAGGTCTGTGGAGCTTCATTAATTTAGACCCTCAAAGTAAGTGTATGCTTATACGTAATTACATTGTGCTGTATGTTTGTGTCTGTAATTTGACAGTGGGACTCCAGTTATGCGGGCCTGGCTTTGCGGCAGTCTGGTACCCTTCCAGAAGGTCTCCATGAGAAGGTTCAATCTGCTCTGTTAACTCTACAGCGGCATGGATGTCTCCTCCGAGATCTTGTCCGAGTTCGAGACCGGGACGTCTTCACGGCCGTTTCACGCGCTCTCGTGGGTCAGCCGGGCTACACGTACCGTTATCTGGACACTCGTCTGTTCACCATCCCCTGGCACTG[T/A]GAAGGAGAAGAGGGCCAGAAAGATGAGAAAGGCAAACCTTGCTGTGACTCCGACCTGAGGGACGCTTGTAAAGCATTATGGGAGCTCAATCAGTTCTTTTGCTCGGATGTAAAGCAGCAGACAAATGCAAGAGGTGTCAAGCGTACCCGCAGTGACACTGAAAACAGCGAAGATGCGCCAGGGGAGGGAATGTGCGAAGAAGAGAGTGTTAAGGACAGGTTAGTTGAGGAGAAAACCATAGAGGAGGAGGAGGAAGACAGTGGACAGGGCTGCTCTCATTCCTCACCTCCTTCATCCACTCCGCCAGCTGCTCAGGCCAGCCTGGTTCAGTTTAACGTCACGCTAATCAACTACATGAACCCTGCAGCCATGACCCAGCTGAAGGAAGAGCCATATTACGGCATGGGCAAAATGGCAGTCGGTTGGCATCATGATGAGAACCTGGTTCCTCTCTCACCAGTTGCCGTTTACAGCTATAGCTGCCCAGCAGAGCCAAAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
e37
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064913 Nonsense 372 568 5 9
ENSDART00000130028 Nonsense 384 579 5 10
Genomic Location (Zv9):
Chromosome 7 (position 37629518)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 36031119
GRCz11 7 36302596
KASP Assay ID:
554-0074.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCTGTTGCGTTGTATGCACAGATGATCTGAACCGGACACATCAGCACTG[T/A]GTACTGGCTGGTGACACAGCTAGATTCAGCTCAACTCACAGAGTCGCACA
Long Flanking Sequence:
TAAATTAATAATATTAAAACAAATTTGTGATCATTTACATACGAATATGTCTTCCTAAAACCATAAGAACTGTGTTTATCTTCAGAAAAGAAATGTCTTTAGATGAATATAATTTAGGTTTGTTTTATGTGATCTGTGAACAATGCTTACAACGATTAAATGTAGTTACTGATGCACAAATTGGCTTGAGGTTTCATTCTTGTATGTCTCTACCATAATGTACCATTCCACAAGAATTAAAGGGATAGTTCTGCCAAAAATCACAATTCTGTCACTATTTACTCAGCCTTTACATGTTTCAAACCTTTGAGTCAAACCTTTTTTTTCATTTGCCTAAACTGTCTTAATGTGTCATCCAATGATAAATGCACAACATGAGGGTGAAAAAAGTGATGGCAGAATGTTGTTGTTCTTAATGTTTTTGTTTCTAATCATTGTGTGTGTGTATGTGGCTGTTGCGTTGTATGCACAGATGATCTGAACCGGACACATCAGCACTG[T/A]GTACTGGCTGGTGACACAGCTAGATTCAGCTCAACTCACAGAGTCGCACAGGTGAGTGTCATCGCTTCAGTTCTACCTCCAACTTCTATAAAGTTCTTAACCAAAACCTCTCTATTTTTGCCTTACACTTAAACACCCCACACTAATATCAGTCATGTTTCTTCAGTGTTGTACGGGTACACTGGACTACATACAGAAACGTTGCTCTGAGGCCTTGGAGAATTTACACAGCGACCCCGAGAAGAACGCCAAGAGCCTGATTTCCCTCCTGCCCTCCATCCTCCAACGCATTGAGGATATCCACAACGAGGTGTGTATGAGAACACGAGTGTTTGCAGCAATGGAAAACCAAATCCCAAGCGCACGTCTCGGGCCGTAACAGATGAGGTTGCTCAGAGGTTTTTTAAAGGTTGTACTTTGCCATTAATTTTTCAAAGCTCAAACAATAGCCGTTCCAGTGGGCCAGACCATCAGTGTGGCCTTGCGTAGGTCTCCGTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34123
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000064913 Nonsense 447 568 7 9
ENSDART00000130028 Nonsense 459 579 7 10
Genomic Location (Zv9):
Chromosome 7 (position 37617163)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 36018764
GRCz11 7 36290241
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGACCTGTGCTGCTCTTTTAGGTGGAGTTTGAGTGGCTGAGGCAGTACTG[G/A]TTCCAGGGCCGGCGTTACGCTCGATTCTGCAGCTGGTGGACTAAACCCAT
Long Flanking Sequence:
CCGCAAACTTATCCAGCATAGGTTTTTCAGAGCGGATGCCCTTCCAGCCGCAACCCAGTACTGGGAAACATCCATACACACTCATACACTACGCTCAATTTAGTTTATTCAATTTACCTAAAACACATGTCTTTGGACTTGGTGGGGGGGTGGGGGGTGGGGGGGGTGGAAACCGGAGCACCCGGTTCACACACAGAAATACCAACTGACTTGATCCAGAAACCTTCTTGCTGTCAGGTGGCTGTGCTAACCACTGAGCCACCACTGAGTTTCACACTTCATGAATTAAATGTATTGTTTGAGTTTTGGCCAGAACAACAGTACCAGTCTGTCCAACTAGCAATAGACAGAGACGACAATTGGGAAAAAATTTGAAACGTTCATATTTTTTTGCAGTTCATTGTGATGTCTCCAGCGGTGTGGAGATGACAGGCTGCAGCTTTAACATGTTGACCTGTGCTGCTCTTTTAGGTGGAGTTTGAGTGGCTGAGGCAGTACTG[G/A]TTCCAGGGCCGGCGTTACGCTCGATTCTGCAGCTGGTGGACTAAACCCATGGAGCAGATGGAGAAAGATTGGAAGGAAATGGAGAGAATGGTAAGAGAGTTGGAGTGAGGCCTCCAGATTTTTCGCTCAGTTCAGCGTCTGACACACAGCTTGCCAGTCGCAGTGTTTGTTTATGAAATGTTTTGGCTAATTTGATTCTGCTTTCTGCTACCAGTTGTAACCTCAGCGCTGTTTAACACATTTTACATTTATTTAAATCCGCAGTTCATGTGGTGAATGTGAAACAAGTGTGCAGGTTCTGTGTGTGGCCATCCAGACGACAAGAATGAGGGAGGCAGACAAATATGTACATGAGAGATTAGAACATTTGAATATGTAGTTTCTTTTATGATCATTTTATGTATATATAATTGAAAAAATGAAAATCCTTATCTGGAATATTATTATTATTATTGCTGTTATTATTATTATTATTATTATTATTATTATTATTATTATTA
Associated Phenotype:
Not determined