Busch Lab

ZMP

si:dkey-12h9.11

Ensembl ID:
ENSDARG00000043026
ZFIN ID:
ZDB-GENE-030131-8246
Description:
Novel protein similar to vertebrate tau tubulin kinase 1 (TTBK1) [Source:UniProtKB/TrEMBL;Acc:Q5SNR3
Human Orthologue:
TTBK2
Human Description:
tau tubulin kinase 2 [Source:HGNC Symbol;Acc:19141]
Mouse Orthologue:
Ttbk2
Mouse Description:
tau tubulin kinase 2 Gene [Source:MGI Symbol;Acc:MGI:2155779]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa8789 Nonsense Mutation detected in F1 DNA Not yet available
sa10498 Nonsense Available for shipment Available now
sa32291 Essential Splice Site Available for shipment Available now
sa23712 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa8789
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063168 Nonsense 169 928 5 14
ENSDART00000138098 Nonsense 169 327 6 10
Genomic Location (Zv9):
Chromosome 20 (position 25947395)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 26018698
GRCz11 20 25917788
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTAACAGTACATGCCGAACCTGTTACATGCTCGATTTTGGATTGGCACGC[C/T]AGTTTACAAACTCATGTCAAGAAGTCCGTCCAGTAAGTAATTATAGACCW
Long Flanking Sequence:
GTCGTTTTGTTGGCTGTGGACGCAATGACCGATTCAACTATGTAGTTATGGAGCTTCAGGTCAGATCATTTATTCTTGTTTTTGTATCGATTGACGTTATCACAAGTTCAACAACCCTGACTCCAGCTATGTTTTCATTGAACTGCAGGGAAGGAACTTGGCCGACCTTCGACGCAACATGAGTCATGGCACCTTCAGCGTCTCCACCACACTCAGACTGGGCCGACAAATCTTAGAAGCTATCGAGAGCATCCACTCTGTGGGCTTCCTGCACAGAGACATCAAACCCGTAAGAATCTGCTCTCTTACAGACAGCCCTGGGCCTAAAAGCACTTCTGATGTTGACAACACTTCATGCACCAGCTGGGCCTCATTATTTCTGTTTAGACTGTATGAACTAATCTTCAATCCCTTTCTTTTTCAAATAGTCCAACTTTGCAATGGGCCGACTTAACAGTACATGCCGAACCTGTTACATGCTCGATTTTGGATTGGCACGC[C/T]AGTTTACAAACTCATGTCAAGAAGTCCGTCCAGTAAGTAATTATAGACCTCAGTCTATGTTTTAAAGATGCTGTTGTCATATATTAGTGTTGCTTAAAGCGGTAGTTAACCTAAAAATCTAATTACAGTCATCATTCACTTATTTTTGTGTAGTTCCAAATCTATGTTTTAGGTTACATCAAAATTTTTTGAACAATTATTGAAGATCGTAATGACAGTGATTGAGGACTCCTTTGACTCCTGATTGAGGACATTTTTAAAAGGCCACAAAAAACATGAAGGTTTCATGAAAGTCTTCTGAATTCCAAACTTTAAATCAGCCTTAATTTTTGGTGAAATATCCCTTAAGTCATAGTGATGTGCTTTTTGTTTATTTGTAATGAATTAGTTTTTTTTTAATTCTTAAACTTTTATAAATTTACCATGTATGTATGTACTGTATGTATGTATGTATATATGTATGTATGTATGTATGTATGTATGTATGTATGTATGTATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10498
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063168 Nonsense 234 928 8 14
ENSDART00000138098 Nonsense 234 327 9 10
Genomic Location (Zv9):
Chromosome 20 (position 25948374)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 26019677
GRCz11 20 25918767
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GACAAGAGATCTGCTGGTGTTCTCAATATCTCCCTCTATCAATACAGGAA[C/T]AAGTTGGAAATATGAAGGAGACATACAACCATCGACTCTTGCTCAAGCAC
Long Flanking Sequence:
GTATGTATGTATGTATGTATGTATGTATGTATGTATGTATGTATGTACTGTATGTATGTATGTATGTATGTTGAGTGTACTACCCTTATAATTAAATTCTATGTGTTTACTTATATTTGCATATATTCTTGTTATTTTTCAAAGCCACGTCCTGTGGCAGGATTCAGAGGGACCGTCCGATATGCTTCAATTAATGCTCACAAGAATAAGGTAACTCTCTTTTCGCACACATACTCAAGTCAATGGCAGATGTCGGTCAGGTTTCTCTGAAACAGAAGGTTATATTACTTATATTTCACTAAAATGCACATCTTTCTATTTCAAAGGAAATGGGTCGACATGATGACCTGTGGTCTTTATTTTATATGCTTGTGGAGTTCATGGTGGGTCAGCTCCCATGGAGAAAAATCAAAGACAAAGTAAGTTCTGCTCAAGTCATCATTTTTCATGGACAAGAGATCTGCTGGTGTTCTCAATATCTCCCTCTATCAATACAGGAA[C/T]AAGTTGGAAATATGAAGGAGACATACAACCATCGACTCTTGCTCAAGCACCTTCCAGATGAGTTTAGCGTTTTCTTTGATCATATCTCCAATCTGGACTACTATACTAAACCAGATTATCAGGTATTGAACTGAGCCTTTCTTGACTAGCGATATTCCTAGTTGTAACCATTGCTCACATGTTTTCTCTTTGTGTTGTAGCTCCTAATGTCAGTCTTTGACAACAGTATGAAGAGCTACAATGTGGTGGAAAATGACCCATATGACTGGGAGAAACTGGATTCAGAGGACACCCTTAATGTGGGAACTCTGGCAACCACAGCCCAGCAGTTGACTCGCCTCACACCTGCATATTTAGGGTAGATATCCACAAACTGCAGTTACTCTTTGATGAATTGAATTGAAGACCTACATTGTTAAATGAAATGCTTCCTTCCAGTATGGCCAATGCCTCTGCAATCCCGGGTGATCTGCAGCGTGAGAACACAGAGGACGTCCTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32291
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063168 Essential Splice Site 392 928 10 14
ENSDART00000138098 None None 327 None 10
Genomic Location (Zv9):
Chromosome 20 (position 25949009)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 26020312
GRCz11 20 25919402
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCACAGTCGTGACAGAAATCTCAACCATGTTCAGCCGCAAATCAGAAAG[G/A]TATGATTCAGAAGGAATTATGATGTTAATACTATGTGTTTGTTATAATAG
Long Flanking Sequence:
GCCTTTCTTGACTAGCGATATTCCTAGTTGTAACCATTGCTCACATGTTTTCTCTTTGTGTTGTAGCTCCTAATGTCAGTCTTTGACAACAGTATGAAGAGCTACAATGTGGTGGAAAATGACCCATATGACTGGGAGAAACTGGATTCAGAGGACACCCTTAATGTGGGAACTCTGGCAACCACAGCCCAGCAGTTGACTCGCCTCACACCTGCATATTTAGGGTAGATATCCACAAACTGCAGTTACTCTTTGATGAATTGAATTGAAGACCTACATTGTTAAATGAAATGCTTCCTTCCAGTATGGCCAATGCCTCTGCAATCCCGGGTGATCTGCAGCGTGAGAACACAGAGGACGTCCTTCAGGGTGAGCGCCTCAGTGAGGCTGATAACTGCGCCCCCATCCCAACACAGCCTGCACTGGGAACCGATGTCTGGGAGGATGTAGAGCACAGTCGTGACAGAAATCTCAACCATGTTCAGCCGCAAATCAGAAAG[G/A]TATGATTCAGAAGGAATTATGATGTTAATACTATGTGTTTGTTATAATAGGCACTGGCGTTGTATTAAAACAGCATTATTTATTAGTATTTCAGTTCTAATATCAGTATATTCTGAAACCATTTAAATGCTGATTCAGATAATTATTTTGAAGGATTTAAACAGTAAGGGCCAGATTTACTAATAGTTTGTGCCAGAGCAAATTGTCTGTTTGCTGTAAAACAGTATTGTCAGTATTTACTAAATATGTGCAATGAAGAGTTGTAAAGGTGTGTAAAGGTGTGAACACAGCTATTTTTGGACCAGACCTTACTGAATATGCATTTTGTAGGAGTTTCTCTGTTAAATGCTAAATTTAATGGGAGGAGAATATTTAAATAAATAATGCAAAAGGATTTATTAATGTTTGCACTCCTCAGATTACAAACATTTGCACCATTATTAAACAGCTAAAAAGCTTAAGGTTTCTCTTTCTTGAAATAAATGCCAGTTTTGCTGGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23712
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000063168 Nonsense 622 928 13 14
ENSDART00000138098 None None 327 None 10
Genomic Location (Zv9):
Chromosome 20 (position 25953199)
Other Location(s):
Assembly Chromosome Position
GRCz10 20 26024502
GRCz11 20 25923592
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATGTCCCGTCTCTAATGCTGTTCCCTTCACAGTCCTCCAGTGCAGCAGTA[C/T]AGACCGTTCAGCCTCAACAGAAGACAGGAGACGACTTTCAGCCTAACAAT
Long Flanking Sequence:
TTTTGCTTAACTAAAGTTAACTATAAATAAATATGGAAATAAATGTATTTTTTATTGCTTGTCTATGTTAGTAAATACATTAACGAAAGGAACCTTCATATTAATTTTGACAATAATCAATAATAAATCAACAATAATTTTAACATAAATAATGTCATTTATTTTTCATAAAATGTGTCATAGAAACTGTAGCAGCAAGCAGGGATCATTTATAGATGCACTACAGTGCTTTCACTGCAACATCACTGTCTCTCAGATTTTGGCCAGCCACTTGAATTTATACTTTACTGTATATCAAAACACCAATGGACAAAAAATGAAGCTGACGTAAAGCATGAAGCTCAGAACATTCTCAATAGATTTCACAGTTCTACCAAGCAGAGGAAGGAAAACACTAATAAAAACAAATATATGAGAGTTTTCTTTTTCCCCTGCAGAGCTCCATTAATAATGTCCCGTCTCTAATGCTGTTCCCTTCACAGTCCTCCAGTGCAGCAGTA[C/T]AGACCGTTCAGCCTCAACAGAAGACAGGAGACGACTTTCAGCCTAACAATCCATCAGGAACTGCAGAAAAGGAGCACAACCACGTGCCAGCAGCCAATTCACCCTCTAGAAGCTCTAACAAGCCAGATGAAAACATGATCTCTGTTAAGGCCTTTGATAAGGATGTGGAGAGTGACTCGGGCTGCCCTGACGGTGGACCTTCTTCAACCCCCAACCAGGGTGAGATGACAGGACACAGTGTTGATGCGGCTCCTGCTTCACCTCGTGAACTCTCTCCACGAGCCAGTCGCATCCCTGTCCGTGACCCGGACTCTCCGACCCGCAAGTGTTTTCCGGCTCCGCTTTCTCCATCCCTGTCGCTGTCATGTGAGCACTTCCCCTCAGCACTGCTGCGTGACAAATTCACCTTCCCCACCGGTTCCCGAGGGTCAGACTGGCAGGTGGAGGAGCCGCTCTCTTTGTCCTCCTCTTCAGGCCCTTTGTCGAGCAAGAGTAAAATA
Associated Phenotype:
Not determined