ZMP

NP_571944.1

Ensembl ID:

Description:

guanine nucleotide-binding protein G(t) subunit alpha-2 [Source:RefSeq peptide;Acc:NP_571944]

Human Orthologues:

GNAT2, GNAT3

Human Descriptions:

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 [Source:HGN
guanine nucleotide binding protein, alpha transducing 3 [Source:HGNC Symbol;Acc:22800]

Mouse Orthologues:

Gnat2, Gnat3

Mouse Descriptions:

guanine nucleotide binding protein, alpha transducing 2 Gene [Source:MGI Symbol;Acc:MGI:95779]
guanine nucleotide binding protein, alpha transducing 3 Gene [Source:MGI Symbol;Acc:MGI:3588268]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41206	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa25395	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa41206

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000062363	Essential Splice Site	54	354	2	9

The following genes are also affected by this mutation:

ENSDARG00000094180

Genomic Location (Zv9):

Chromosome 8 (position 26085943)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	25213861
GRCz11	8	25233000

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTTATAGGTGCTGGTGAATCAGGGAAGAGCACCATTGTAAAACAGATGAA[G/A]TGAGTTGAAACACATGCGATATACAAAACACATGCTCAGATATGACAATT

Long Flanking Sequence:

AGCTCAAAGGCGAATCAAAGTGTCAGTGATCTTCTGAGAAGCTTTCCCTAACACAAATCCAATTGGGTCACTTTATAAGCAGGCTCATAAGCCTTCCTCTGACCTGCCCATCAATGGCAATCTATGAGTTTTTCTTGACAGGTTATCTACAGCTTAACATTGACCTTGTTATTAAAATCAATATCCATAGAGAGGAAAACAAATGGTTTAAATTCAGGAAAAATTCAGGCATTATGTTATCTGTATGAAGTGATACATCAATGTCACAATGGAATATGTAACCAAGGGACTAAGATTCAGCTCAATGTGGTTTGTTCAAAGACCTTCGAATGAAGTTAAAAGTTACAGATGGAGTTCATCGTGCCAAAACTTTGTGTGATGTTTGGTTTAAAAGCGTTTGAGGACTCGTTTGTCCTTTATTTGCTCTACATCATGTTTTTTCCCCTTTGTTTTATAGGTGCTGGTGAATCAGGGAAGAGCACCATTGTAAAACAGATGAA[G/A]TGAGTTGAAACACATGCGATATACAAAACACATGCTCAGATATGACAATTTGTATCTTTGTAGACAAGCTGTGTAAGCTCTTGAATTGAGATTTAGGTTTCTTGCATTCTAACTGAATTAATCCTTAACATTTAGTGTGCATTTGGGGAATACCAGCGCTTACCTACAGTAGAGTTGAGACCCTAAACTGTTATCACTAGGTGGTAGTGAATGAGGAGCCTGTCCTTTATCTTCAAATCATTAATAAAAACCCCTCTTGTTCCTGTCCAAGGATTCTCCATCAAGGTGGTTATACAAAAGAAGAACAAATGGAGTTTCGATCTATTATTTTTGGCAACATCCTGCAGTCTGCTCTGGCCATCATCAGGGGCATGGAGATGCTGTCAATCAACTTTGGATCGCCATCTGCACAGGTCTGCAGGACTGCTCTAAAACAAACAGAACAATTATTAGTGTGAAAATGATTCTCTAAAAAGCATGTTATGATGTTCAGTACAAGC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa25395

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000062363	Nonsense	108	354	4	9

The following genes are also affected by this mutation:

ENSDARG00000094180

Genomic Location (Zv9):

Chromosome 8 (position 26082296)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	25210214
GRCz11	8	25229353

KASP Assay ID:

554-7833.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTAACAGTGCCCCCTTTTTCTGTCTCTTGTAGGAGGATAGTCAAAAGCTC[C/T]AGAACCTGTCTGACTCCATTGAGGAGGGCACCATGCCTCCAGAGCTGGCA

Long Flanking Sequence:

ATTCATTGTTGCTCTTGGTTGTGTAAATTGCTTCCTTGTCCTCATTTGTAAGTCGCTTTGGATAAAAGCGTCTGCTAAATGACTAAATGTAAATGTAAATGTAAGTGTAGTTACCACATAAAGGCTGCCAAGTGCTAATTCCCTGCAGATTTTCCCATGATCGCAGACCGATATGTTTGCAAACTTGTTAACTTGCAGCATACTAAAATCAGGCTCAAAATCCTGTAGTGTGAACAGGCAATAGTACAAATAACTGATGTAAAAATGCACTCCACTTGTGAGTACTACTGAAAATCCAATCAAGAACAGTTTCATAAAAGTCAACCATTTTCTCAATTTGGATGATCCATTCCACCTGGATCATGTACATCATAATAACGAAATCTAAATCTGAAGCTATGTCTATGCAACTTAATGAGTAATAGAATCAGCTGACTTACCACATGGTGCCTAACAGTGCCCCCTTTTTCTGTCTCTTGTAGGAGGATAGTCAAAAGCTC[C/T]AGAACCTGTCTGACTCCATTGAGGAGGGCACCATGCCTCCAGAGCTGGCAGACGTCATCAAAAGGCTATGGAAGGATGCAGGCGTGCAGGCCTCTTTTGATAGAGCTGCCGAGTACCAGCTGAACGACTCTGCTGGATAGTGAGTAAAACACTCAAAAGGCCCAGCAACACACATAAAGTTGAATTGTGCCTGAGGAAGCGATTAGACCATGCTTATTTGATGTTGAATGCCGTTTTCATGCTTTGGTGACTTTCAGTACTTTAGCAGATGAATAATTCAGGTGTGTCTGTACATGAATTGCTGACTCATCTCCCACAGCTACTTGAACGAAATGGACAGAATCTGCAAACCTGACTACCTTCCCACCGAGCAGGATGTGCTGAGATCTCGAGTCAAGACCACTGGTATCATTGAGGAACAGTTCGGTTGCAAAGAGCTCCACTTTAGGTGTGTCTTACCAGACTGAGAGGATGGAAGCAATAGTTGGTTCAAACTTAGA

Associated Phenotype:

Not determined