Busch Lab

ZMP

si:ch211-220f12.1

Ensembl ID:
ENSDARG00000042249
ZFIN ID:
ZDB-GENE-050419-154
Description:
FERM domain-containing protein 4A [Source:RefSeq peptide;Acc:NP_001122007]
Human Orthologue:
FRMD4A
Human Description:
FERM domain containing 4A [Source:HGNC Symbol;Acc:25491]
Mouse Orthologue:
Frmd4a
Mouse Description:
FERM domain containing 4A Gene [Source:MGI Symbol;Acc:MGI:1919850]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa7451 Missense Mutation detected in F1 DNA Not yet available
sa36573 Nonsense Mutation detected in F1 DNA Not yet available
sa666 Essential Splice Site F2 line generated Not yet available
sa43047 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa7451
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093131 Missense 122 1035 5 24
ENSDART00000147284 Missense 91 1003 4 22
Genomic Location (Zv9):
Chromosome 18 (position 8017443)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8594821
GRCz11 18 8552840
KASP Assay ID:
554-4037.1 (used for ordering genotyping assays)
KASP Sequence:
ATTGTGTTGATGTATACGTTTCCTCTTTTGCAGGTTCTACATTGAAAGCA[T/A]CTCTTACCTTAAGGATAATGCCACAAKCGAGCTGTTCTTCCTCAATGCAA
Long Flanking Sequence:
TTTAATTGTTGAGATACAAAAAAGCAAATTAAATTAAATGTTTCAATTAAATGTCTTCCATGAAGATGTGAGGATCCTTGATAAGCAAATCATCTGCATTCAATATATTCAGTGTTGAACACTACTGCGTTACGAATGGGACTGTTTTAATGTAAGAAGTTCATTATGAAATCTAATTACATAATTATTAATCAATCAAAGTATTTTTTCAATTTGTTTTCAAATATTTATAAATTAGGACATTACTGACTACTTTAATGTAATAGTTTGGTTTAACTTGTGTCTTTCAGTGAGCTCATTGAAACTGTGTAAATGGTTGATGAAGTGCAATTAGAATTGATTACTTGTACTGAAAACCTTTAAATCATATTCATAATAACCTGTGATTGGTTGTTTTAGTCAGTGAATTGGTTATATTATTTAAGTGACTACTTCTGTTTTTACTTTGCCATTGTGTTGATGTATACGTTTCCTCTTTTGCAGGTTCTACATTGAAAGCA[T/A]CTCTTACCTTAAGGATAATGCCACAATCGAGCTGTTCTTCCTCAATGCAAAGTCTTGCATCTATAAGGTACGTGTTTATCACTGGTCTACCACTAGAGAGCAGTATTAGCTACTGCCCCTTTGCTTCCTTGAGGTCTGGATGCAGACTTGGTGCATTTGCAAGCTGAGTTGCCTTTTTATGCCCACACCTAACTCCAATCCTAACCGCAACCCTCACAGTGACGTCATCAGCACCGTTGAGTGCATGGTGTCTGACATTGCAAGTGTGAGATATGCAGTGTCAGCTTGCAAATCCAAGTCTGCATCCAGGTACTATTGCTTTGGTCCTAAAATTCCAAATAATTATACAAATAAAACAACAATTGATGTGTGCCAAAGAGATGTAATAAATTAATAAAAGCATATGAATGAGTGTAAATATAAGCATCGTCATATGTGTTAAGGATCATTTGTATAGTAAAATATTAGCTAACCGAGCTGATTTTATATCCAAACATTAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36573
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093131 Nonsense 253 1035 11 24
ENSDART00000147284 Nonsense 222 1003 10 22
Genomic Location (Zv9):
Chromosome 18 (position 8005242)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8582620
GRCz11 18 8540639
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTCTCTCTCAGGATAAGCAGGGTATCCCATGGTGGCTGGGCTTGAGTTA[T/G]AAAGGCATTTTTCAATATGACTACCAGGACAAAGTCAAACCAAGAAAGGT
Long Flanking Sequence:
ACTGTACATTCTCCCAGACTTCCGAGATCCACTCCCACATGTTTGCTTCTAATGTAAATTGTTTGCATGTGTAACATCCATAACACACTGTCAATGATTCCTTCTTTCTTCTCTCTCACAGCTATATGAGTATAGTGGAGTCCCTGCCCACATATGGAGTGCATTATTACGCTGTTAAGGTGGGTCATGGAGCTCGGAGGGGAAATTTATAAGCGCAGCCATCGGTACACACACACACATTCTCACGGCCTGCAGTATCGGCTCTTTCCCTAAGTGTTAAAGGATGCTTAAGACTCGGTGTGTTTTAGATAATCATGCTGTCATCAGCCATGAGCTGACACTTCTGCTTGTGTGTTCTTGTGTGTGTGTGTGTGTGTTTGTTTTTATATCTTATGGGGACTTATGCGTGCGTGCGTGTGTGTGTGTGTATTAATGCTTTTTTTCTCTCTATCTCTCTCTCAGGATAAGCAGGGTATCCCATGGTGGCTGGGCTTGAGTTA[T/G]AAAGGCATTTTTCAATATGACTACCAGGACAAAGTCAAACCAAGAAAGGTAAGTCCCTCTTTCCTCTGTGGACTTGACACGGTTTGACTTTTGTTTGTGCTCTCTCTTCATCTTTATCATCCTGTAATGGTTTTAGCTTGCTGGTGGTAATTTGTAGTTCTTGGTTAGTGTAATTCATCTTGCATAATTTGTGCTCCAAACAGGAAGGATACCGTGACACTTTTCTATGCAGATACACTGATGTTTATTTGTCCAATGATAAAATTACACCGCAAAATGGGTCTTACTTAGAGTTTTGACTTGTTTCTAGTCCAAATATCTAAAAAGAATTAAGAAGCATTTTTTAGATCTATGAAGTAGATACTTGCTTAAAGCAAGAAAATAATCTGCCAATCGGGTAAGAAAAATGAACTTATTTCAAACCAAAAACAACATTATTTTGCTTACCCCACGGGCAGATTATTTTAACATAGGCTCATTCAGAAAACGTAGCCCTATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa666
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093131 Essential Splice Site 295 1035 12 24
ENSDART00000147284 Essential Splice Site 264 1003 11 22
Genomic Location (Zv9):
Chromosome 18 (position 7995047)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8572425
GRCz11 18 8530444
KASP Assay ID:
554-0574.1 (used for ordering genotyping assays)
KASP Sequence:
TGTACTTCAGGGAGAAGAAGTTCTCAGTGGAAGTCCATGACCCGAGAAGG[T/C]AAATCTACATTACAGTCTGCACATRCTTGCTCACACACACAAACTGGCAA
Long Flanking Sequence:
AGCGCTGCATTTTGAGGGGTTACTACAGCACACACACACACAAACACATCACCCTGAACTCACTGTAAACTCCGCCCACGCAGGAAGCGTGTCTCCCAGAGGGAGGAGAGGCTTGGAAAGAGTCTGACTCCTCCCACTTTTGCTTGCTCTCTCTCTTTCTCTCTTCATCTCTCTAGATCCAAACAGTCTCTCACTTTCTACACATATACAGAGGAGGACTCATTGTTCCCCTGTGCCTAAGGAGGATTTTAAACACACACATACTCGCCACATGCACGAAAGTGAACGGAAAAGTCAGATATCTTGGATTCTGGATTCTCTTTTAATGTCCTGTTGTGATCTGGAAGGATTCTGAAGAACATCCGTGGAATGTTAGATCAAGGTTGTGGGAATGTTCTGAAAACGTTCTCTCGTCTCTGCAGGTGTTCCAATGGAGACAGTTGGAGAATCTGTACTTCAGGGAGAAGAAGTTCTCAGTGGAAGTCCATGACCCGAGAAGG[T/C]AAATCTACATTACAGTCTGCACATGCTTGCTCACACACACAAACTGGCAACCTGATTTCACCAAGTAAAACATGTTACTGGGTTAACATCTATGTTGATCCTGGAACAACATTCCAATCAGCCAGTCGGAAATAAGGGGTATGTTTAGATGTTTATGTTTAGGCTAACAGTTAGGTTTATGCACTTCTACATGATTGTTGTCCAACTATTATTCCCCTCTGATTTAGGGAATAATTTACAGTTATGGTTGGGTTTAGAGGTAGGGAATAGGTACTGTATGGATTACTTTTTCTAACAAAAATTATGCTCCAGGATCAACATAGATGTTAATTGAGGATTGCATCGTGCATGGCAAAATCATGACGTGCCACATACATACACACACAGATCATGGACTATAAGCTAATAAACAATATTGAGGTAAAGTTGGTTTTATAATCACACATTCAAACGTTCTTCTTAATATCCTTTTGGAAAAGTATTCCTTGCAAATTCGAAAT
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa43047
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000093131 Nonsense 468 1035 16 24
ENSDART00000147284 Nonsense 436 1003 15 22
Genomic Location (Zv9):
Chromosome 18 (position 7979206)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 8556584
GRCz11 18 8514603
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCCGCCCACCGTCAGACGCAAAATTGGCACAGCCTTCAAACTGGACGAA[C/T]AGAAAATCCTGCCCAAAGGAGAGGTCAGTGACATCCAACCTCATCCATCC
Long Flanking Sequence:
TTTTGTCTTACCTGATTTCTGAAACCCGGTCGTCGCATCGAGTTATGGTTACCACGACAAACTAACCGGACAAACTGGCTGCGGCAGGAAAGCGCTCCACATGGAGATGAGCTGTCAGCTGGCGAGCTGGCGAACAAGAGGAGCGGTGTCACACTGCCCTGTAGCGTTCACTTGAAAAAACGAAATGCAGCCATACATACCTCCGGCCACCTAAATCGCGTTCTCCATAAACGTCTGCAGGGCTACAGCTTGAGCTTGGGTTGGATAAATTCCTTGCTCTGTTGAACATCATTTGGGAAATATTTAAAAAAGAATACACAGGAGGGCTAATAATTTTGACTACAATCATACACAACAAATGCTAAAGAAAAAAGACGATAACAAAGTGTGATGTGTTTCAGGAGCTGACTGGAAAACTTCCGAAGGAGTATCCTCTGGATCCTGGCGAGGAGCCGCCCACCGTCAGACGCAAAATTGGCACAGCCTTCAAACTGGACGAA[C/T]AGAAAATCCTGCCCAAAGGAGAGGTCAGTGACATCCAACCTCATCCATCCCACTGACCACAGTCATGACCCGGCAACATGGGCATTCAGTTTATAGTCTGATGTAAAGTTAGTACCACTGACCACACTAACCACTACACAATTGTTTAATCATAAAACTGCCCTTTAAGTCATTATGCCCAGGCATTATTGTGTATGTGTGTGTGTGCAGGGATCTATAAATAGCCCCAGTCTGGCATGATCAGAGGAAGTGGCGATAGTTCAGTGTGTGTGTTGAGTCTCAGCCAAAGGAGCCACATTACAAACCCCCAAAAAAGAGCTTGTGCTGTGTGAATGTGCGCAAAAACAAGCTGATTAATGTACAAGGTCACAATGTCACCTTTTCCTTAGCGTGTATGTGTGTGTGTGTTTGCGCATGACTGATGGTTGTTGATTTTGGGTGATTAATCGAAGGCATTGATTAGAGGCCACAATATCTTGGCTGTCTCAAAGTGTGTGTGA
Associated Phenotype:
Not determined