ZMP
si:dkeyp-35f12.2
Ensembl ID:
ZFIN ID:
Human Orthologue:
PAM
Human Description:
peptidylglycine alpha-amidating monooxygenase [Source:HGNC Symbol;Acc:8596]
Mouse Orthologue:
Pam
Mouse Description:
peptidylglycine alpha-amidating monooxygenase Gene [Source:MGI Symbol;Acc:MGI:97475]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45393 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa16146 | Essential Splice Site | Available for shipment | Available now |
| sa15072 | Essential Splice Site | Available for shipment | Available now |
| sa21661 | Nonsense | Available for shipment | Available now |
| sa34842 | Splice Site, Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa45393
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000061639 | Essential Splice Site | 91 | 909 | 3 | 24 |
| ENSDART00000136976 | Essential Splice Site | 91 | 1017 | 4 | 27 |
The following transcripts of ENSDARG00000042071 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 10 (position 7700290)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5709340 |
| GRCz11 | 10 | 5710559 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACTACTGTATGGCTGTTCCTGTCCCAACCTCACGGGAGGCCTATATTGG[T/A]GAGTAAAGGTTTTATTAACTGTAGTAAGCACAATTTCTATATAATTTCTA
Long Flanking Sequence:
AGAAACGCGCCAGCAATGCGCCTTAACACACCGTCTTTCTAGACTGGAACACCCATGAGTCCACAAAGTGGCGCAAATGCATTTGCTATTTAAACAATGTAAAAATGGAAAATTTAATTGGCAGAAAATGGGAAAGGTAGGGTTGTGCTGGTCTGAAAATATCCGCCTTGCGCCTTAAAGATGAGCATTTAGATTGGGGTGTATGATAGGGCCCTGGATGTGCAAATATAAAGCCAACTTTACTAGTTCATTTCAGCAATTCCTATTGTTTTACAAGTTAAATTCAAAACTTTGGATGCATTCATAACGGTTTCACTTATCTTAATTATATTCAGCATTCCAGGTCTGATTTAGTAAACATGATCAGGAATGTGAATATGTGAATCTGAAATATTCTACGAACTTTCTAATATATGCATCTGTGTGTGTGTTTTTCAACAGTCTGATAGCTACTACTGTATGGCTGTTCCTGTCCCAACCTCACGGGAGGCCTATATTGG[T/A]GAGTAAAGGTTTTATTAACTGTAGTAAGCACAATTTCTATATAATTTCTATTAAATAGCTCAGTAAACTACTAATTAGCTGCTTATTAACAGTTCGTAAAGTAGTCGTCCGCTTTAGGTATTGTGTAGGATTAGGGTTGTAGAAGGTCATACTTTATACGTTCTAATAAGCAGCTAATATCCTTATAGCAGTGTAACGTACAGTCTGTAGATAAAACTACGTATTGATTTAAAAAAAAAAAAAAACGATCTGGGTTCAGTCTAAGAGGACAGTTACGATCACCTGGTGCAAGGAAGTCTGCTCTGAGCATGTCTGGGTGACAATTCAATTACGCCGGTACACTTAGGCCCCGTTTACACTAGTGCGTTTTAGTTTTAAAACGGCGTTTTAGAATGAAAATGATCCGCGTCCACACTCGCGTTTTACCCAGCGTTTCTGAACTGCTCTCCGTCCACACCAAAACGCTGAAAACGCACATCACGTGACCACACACACACTCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16146
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000061639 | Essential Splice Site | 120 | 909 | 4 | 24 |
| ENSDART00000136976 | Essential Splice Site | 120 | 1017 | 5 | 27 |
The following transcripts of ENSDARG00000042071 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 10 (position 7706527)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5715577 |
| GRCz11 | 10 | 5716796 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACATGATTTTATATGGCTGCAAAACCCCTTATGCTACTCAAGGATACTGG[T/A]GAGTTCCCTCTGATAYTTTTATAAGCATTTTCATTTGCAGACAAAACTAA
Long Flanking Sequence:
AGCTGACTGTAGTATTGGTAACCTGGCAACCAACAGGAAGCAAGGCAAGCATAATGGAGACAGCTATTAGTTAGTGGGTGTGCTGTTCACTAAGTCAAAGTTTATACAGCAAATGAGTTTCCATCTTCCATTTTTCACATTAACCTTATTTAGCATTAAAAAAATTAAGAGATTTTTTATTATTACTTTCACATTTTTGGTGTTTCCATCATTCGTTTGTCATGTGATACATTAAAATAGAATATTTATGGTGAAACCTAGATATTGTTCGTTTGCAGAAAAGCTATGACATTGCAATCATTACAATTTATCAAGAAATTTCAGATCGTCATTAAAGATGTTCATCCTACCATCACCGTATTCTCTATAAGATTACCAAGTTTACCTTAAAATCATCTCTTCTCTTCTCAGTGGACTTTGTTCCCCATGCCAGTATGGACACAGCCCACCACATGATTTTATATGGCTGCAAAACCCCTTATGCTACTCAAGGATACTGG[T/A]GAGTTCCCTCTGATACTTTTATAAGCATTTTCATTTGCAGACAAAACTAAAGTGCCGCTTTACAAGCACTGTCAATTCAAGACAACATTTGTTATGTTGATTTACCTTATTCTAATATTTTAAAGTAATCAAGTTTCAGTGCATCCCACTCCTCTTGCCACTTATTTAAAATGTAAACGTTGATAAAAGGTCTCATTTCTGAAGTAGAAATTTGTTCACCACTTGCTTCAATGCGTCCTTAGCAGCTGCATCAGCCCGCTCATTTACTAAAAGCCTAACATGTCAGGGAACCCAGCAAAAAAATGATGTGATAAAACTGGTTTCGTAGATGGTAAACTTAAGTTAAATATTAACAATCCAAGAATGACACTTGGAGGCATGATTTGGAGTCTGTAAAAATGACAGAGACTGTAAGAAAGATGTTGAAATTCAGCTTCGAATCATGGAAATAATTACATTTTTAAAAATATTTTTAAACAGAAAAGCATTATTTCAAAACT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa15072
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000061639 | Essential Splice Site | 370 | 909 | 12 | 24 |
| ENSDART00000136976 | Essential Splice Site | 370 | 1017 | 13 | 27 |
The following transcripts of ENSDARG00000042071 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 10 (position 7734850)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5743900 |
| GRCz11 | 10 | 5745119 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CAGGCCAGACCATATGATGTCCATGAAGCATGAAKCTTNNNCTCAAAAAG[G/C]TACCGTACAAAATCAAACACTTCAAGATTTTTCATACACAACTCTACATG
Long Flanking Sequence:
ATGCTTGAAATGTACCTGAAATTCTGATTTGAGTCATAAGCTTTAGAGGATTGATTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGTTCTGTTGGTTATTTTTATACTTGCTGCTTTGTAGCTGTACTTTTTAAAAAAAATTTATTTTGCTAATAGTTTGTTCACATCTCGTTGTTTTCCTCCTCACAGAGGCACCTCCAACGATGAGATGTGTAACTTCTACATCATGTACTACATGGACAACACCCATGCTGTGCCTTACATGAACTGCAGAGATGATGGCAGCAGTGAGCTCTTCAGAAACATCCCTTCTGAGGCCAATATTCCAATCCCGGTCAGGCCAGACCATATGATGTCCATGAAGCATGAATCTTCTCCTCAAAAAG[G/C]TACCGTACAAAATCAAACACTTCAAGATTTTTCATACACAACTCTACATGTAGGCAGTTGAAACAGATAGCTTGTGGAATCACTGAATGTTGCTATGTTTTTGGGTAACTCAAACACTGTTTTTCTTAATATTCTCATTTGCTTATTTGTCATTTAGATGCTGTGGAGCTTCAGGAGCCCAAGAGAGATGAGGAAGTACAGGATCAAGGTAAGCTTTTAAAATAATTCATAAGAGAATTTTGTTCATGAAACATAGTCATTACTGAAATATCATTACAAATCCCCCTCTATAAACAGATGTAGAGGTTAAATTATGCTTTTCAGTAAAACTATGGTATACACCAGGGGTTTTCAAACTTTTAAGTCACCCCGCCCCACTCCCAAGTTTGCCCCAATTTCACTCGCCCCACCAGGCACCCCTCCCTCCAACCAGAAATATAATGTATGTGCAAACATCATTCACATATTACTTCCTGTGTTTAAAGTCTCAATTACATTGA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21661
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000061639 | Nonsense | 385 | 909 | 13 | 24 |
| ENSDART00000136976 | Nonsense | 385 | 1017 | 14 | 27 |
The following transcripts of ENSDARG00000042071 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 10 (position 7735049)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5744099 |
| GRCz11 | 10 | 5745318 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCATTTAGATGCTGTGGAGCTTCAGGAGCCCAAGAGAGATGAGGAAGTA[C/T]AGGATCAAGGTAAGCTTTTAAAATAATTCATAAGAGAATTTTGTTCATGA
Long Flanking Sequence:
GTTCTGTTGGTTATTTTTATACTTGCTGCTTTGTAGCTGTACTTTTTAAAAAAAATTTATTTTGCTAATAGTTTGTTCACATCTCGTTGTTTTCCTCCTCACAGAGGCACCTCCAACGATGAGATGTGTAACTTCTACATCATGTACTACATGGACAACACCCATGCTGTGCCTTACATGAACTGCAGAGATGATGGCAGCAGTGAGCTCTTCAGAAACATCCCTTCTGAGGCCAATATTCCAATCCCGGTCAGGCCAGACCATATGATGTCCATGAAGCATGAATCTTCTCCTCAAAAAGGTACCGTACAAAATCAAACACTTCAAGATTTTTCATACACAACTCTACATGTAGGCAGTTGAAACAGATAGCTTGTGGAATCACTGAATGTTGCTATGTTTTTGGGTAACTCAAACACTGTTTTTCTTAATATTCTCATTTGCTTATTTGTCATTTAGATGCTGTGGAGCTTCAGGAGCCCAAGAGAGATGAGGAAGTA[C/T]AGGATCAAGGTAAGCTTTTAAAATAATTCATAAGAGAATTTTGTTCATGAAACATAGTCATTACTGAAATATCATTACAAATCCCCCTCTATAAACAGATGTAGAGGTTAAATTATGCTTTTCAGTAAAACTATGGTATACACCAGGGGTTTTCAAACTTTTAAGTCACCCCGCCCCACTCCCAAGTTTGCCCCAATTTCACTCGCCCCACCAGGCACCCCTCCCTCCAACCAGAAATATAATGTATGTGCAAACATCATTCACATATTACTTCCTGTGTTTAAAGTCTCAATTACATTGAAACATAAATGCACATTTTACCTGATTCAGTGTGATGGCTGAGCCTGTTTTTGTGAGGACAACATGCTAATCTGTGGTTGGATTTCTGACAGGACTAACTGTAAATCCTCTTCTACTGTCAATAAGTGTGAGCCATAGCCTTTGATACATATGTACATACAGAAAATGCTGCTTCGCAAAGCCAAGATCGCAGAGCCCTG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34842
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Splice Site, Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000061639 | Splice Site, Nonsense | 672 | 909 | 19 | 24 |
| ENSDART00000136976 | Splice Site, Nonsense | 780 | 1017 | 22 | 27 |
The following transcripts of ENSDARG00000042071 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 10 (position 7765207)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5774257 |
| GRCz11 | 10 | 5775476 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCATCAATTACTCAAGCAAGGAAATCCTGGATTCCTTCAGTCCAGACACA[C/T]AGGTACAGATTGCAGCACATTCGGTACATACAATGTGCACACTCAGCTGA
Long Flanking Sequence:
TTTGGGGAACATCCTCAAACACTCACTCACTCACCCACACTCATACACTACAGACAATTTAGCCTACCCAATTCACCTGTACCGCATGTATGTGGGGGAAACCGGAGCACTGGGAGGTAACCCATGCAAACGCAGGGAGAACATGCAAACTCTGAGCCAGAAACGGCAACTGAGCCGAAGATCGACCCAGCAACCCTCTTGCTGTGAGGCAACAGCACTACCTACTGCGCCACTGCTTCGCCCTGTGTTTAAACAAGAGCTATTAAATATCAATGCAAAGATGAAGTGCTATAAGTGAAAATAGAAGTTATTTGAACAAACAAGTAAAGCATATAAGTATTTCTAACAAAATGTGTATTCATCTTTCTACTGTTATTTCTTCAGGTGGCCTACTCTACGCTGTGAACGGAGAACCTCCATACGGTCAGGCTGCACCTCTTCAGGGGTTTGTCATCAATTACTCAAGCAAGGAAATCCTGGATTCCTTCAGTCCAGACACA[C/T]AGGTACAGATTGCAGCACATTCGGTACATACAATGTGCACACTCAGCTGAGCATAAGATTTGCTCAAAACAATCAAGAGGAGCTGTGATGTAACTGAGAGTTGTTTATTAGTTGGTGTACATGTTGCACATGTACAGTAAAGGCCTCGGTTTCTTCATACTCTACATATAGTGATGTCTTTAATATGTGGCCAACTACTACTGTACATGCTTTAGGATGCATGTTCATTCCCATAGGCAGATATCTTTACTTGTTATGTATTGATTTTGTATTTTAGTGTCTGTTGAAATCCTTGATTCTGATTGGCTGGAAGGTGTGCAATAAAATTGTTTAATGCGCAAGTCAGTTTCGATCGTCGCTCCAAATAAATCAAACTGTACTAGTAAACATAGTAACTTAGGTGACAGATGATGTAGACTTTATTTGTCTCTGTAATCTGGAGAACACAGATGTGTGTGTTTCACCAGGGAGCTGATTAAGACCAGCCAACTCACAAATAT
Associated Phenotype:
Not determined