Busch Lab

ZMP

hdac4

Ensembl ID:
ENSDARG00000041204
ZFIN ID:
ZDB-GENE-061013-95
Description:
histone deacetylase 4 [Source:RefSeq peptide;Acc:NP_001034447]
Human Orthologue:
HDAC4
Human Description:
histone deacetylase 4 [Source:HGNC Symbol;Acc:14063]
Mouse Orthologue:
Hdac4
Mouse Description:
histone deacetylase 4 Gene [Source:MGI Symbol;Acc:MGI:3036234]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa25438 Nonsense Mutation detected in F1 DNA Not yet available
sa41547 Nonsense Mutation detected in F1 DNA Not yet available
sa14812 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa25438
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036277 Nonsense 52 1023 2 25
ENSDART00000124870 Nonsense 52 1023 2 25
ENSDART00000127567 Nonsense 52 1026 1 25
ENSDART00000135537 None None 850 None 21

The following transcripts of ENSDARG00000041204 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 47107732)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 46239012
GRCz11 9 46039491
KASP Assay ID:
554-7829.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCCAGCGTGAGCATCAGCTGCAGCAGGAGCTTCTGGCCCTCAAGCAGAAA[C/T]AGCAGATCCAGAGGCAGCTCCTGATCGAAGAGTTTCAGCGGCAGCACGAG
Long Flanking Sequence:
AGATAGATAGATAATGCCTTTATTTATATATGACAAAATAAATAAATATTGTTGTGTAATTGAATAAATAACATTATGGTTTGCTGACATAATTCAGACTGTTAATTAATAGCAATCCATAAATGAACATATATCCATAAAGCGCTTATGTTTGTGACCTCAATACCATGATGATTTCTGAAGGATTTGTCTTTGCAGCAGGAAAATTCCTTCTGTCTAAATGCCCTTTGAATGTTGACTTGGATTAGCTTTGCATGAAAGTTTTAAAAGCTTTGTGTACTTATGTAGTCATGCACAGTTTGCGTGTGTGTGCTCATTTGCTAACCGTCTCCTTTCTCTCTCTCTCTACAGTTGATGTGAGTGTGGCGCTGCCACTGCAAGTGCCACCTTCTGCCATCCCTATGGACCTGCGTGTGGATCACCAATTCGCCCTGGCGCCGACAGACCCGGCCCAGCGTGAGCATCAGCTGCAGCAGGAGCTTCTGGCCCTCAAGCAGAAA[C/T]AGCAGATCCAGAGGCAGCTCCTGATCGAAGAGTTTCAGCGGCAGCACGAGCAGCTCTCCCGACAGCATGAAGCCCAGCTGCAGGAGCACGTCAAGGTGAGGCTGCTGGGATTTCTGTACGCCAACCTGGATGTTAGCATCCCCCTGGATCCAACCAAATAAGACAATACGATTTTTCCATTGGCCTTTGGTGCTAGCCAGAATGTGTGGATATGGATTTGTTTGTTTAATGGATACAACTTTTGATTCGTATGTAATTGCTGGATGCTCAAAACTAAAGTTAGGTTATAAACAAACTACACTACAGCAACAGTAGCCGTGTTATCATTCAGAGATGCAAATTAAAGCTGTGATAGGTGAATGTCTTTAGAATTTTTTATATGCTCGTTGAACGGCTCCTGATAGCAATAATCAAATTAAGTTGTCTAAATGTGTTTTTTAATATTCTGTGAAAGGCATAGGAACAAGAAAAGTTAGTCCAATCGAAACATTTGGTCTAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41547
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036277 Nonsense 145 1023 4 25
ENSDART00000124870 Nonsense 145 1023 4 25
ENSDART00000127567 Nonsense 145 1026 3 25
ENSDART00000135537 None None 850 None 21

The following transcripts of ENSDARG00000041204 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 47095447)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 46226727
GRCz11 9 46027206
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCGCTCTTGATCGACAGGCGCCGTGGCGAGCACTGAGGTCAAGATGAGGT[T/A]GCAGGAGTTCGTCCTCAATAAGAAGAAAGCGCTGGCCCAGAGGAGTCTCA
Long Flanking Sequence:
TTCATCCATCTGATGTGTTTCTTTCAAAGAGGGAACAATAGTGAGGGTAAAAAAAAAGACATCTTTGTTTAAACACGGCGGTCTCAGTGGAACTGGAATAAAGAGTTCGCTCTTTTTAAGACCGGATAAAGGGGCCGTTTCTCTCAGATGTAAAGAGATATCTGAACCTGCGCTGGAAGAGCTGTTTATCGACACCAGAAAAACAAGCGTCGGCCTTTGTAGTCGTGATCAATTGGCCACCGTTCGATCTCCTCCGTCTCAGACTATTAAGAGTTTTTTAAGACCATTTAGAAGACGAAATTACAGCGCCGCAAATTACAGGGTTTAGAAATGGCGGAGGAATTGACAGTCACAAATGCACAGGAGGCTTTTAGAGAAAGCGAGCGGTATAACGCTGAGAGAATGCCATTAATGTCCTGCTGCTTGCTGTTTGTGATCTTCCTGAACTGTGCGCTCTTGATCGACAGGCGCCGTGGCGAGCACTGAGGTCAAGATGAGGT[T/A]GCAGGAGTTCGTCCTCAATAAGAAGAAAGCGCTGGCCCAGAGGAGTCTCAACCACTGCCTGCCCAGCGACCCACGCTACTGGTACGGGTGAGTATCAGCCTGCTTAAAAAAAATGTTACAGCTTTTTACTGGTCCTCTAAGGTCTGGGCATGTTCCGGTATAAGTTTCTGACAGTGTGATAGCCTTGGATGCAACACAGTATTGTGATTACTGCTCTTAAATATATTATTTTTAAATGTCTGGTTAAAAAACAGCCCTATTACCCATTGAACACAATAATTTTAAGAAACATTTCAAATATTTTGGAGCAGTAAACATGTCAGACTAAGTAATTAAAATAAATTATTGACTTCTGCTATATTCATTAGTTTTAAAAACACTGATTTCTTGTAGAGGCATCATTGGATATCTGTCTCTTCTTTGGTTATAAAGTAAGCCACAGCACTGTTCAGATCTATAGCATGATTGGATGTTGGTGCAAAAGCGATTTGTTCTTTAAA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3746
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036277 Essential Splice Site 333 1023 8 25
ENSDART00000124870 Essential Splice Site 333 1023 8 25
ENSDART00000127567 Essential Splice Site 335 1026 7 25
ENSDART00000135537 Essential Splice Site 160 850 4 21

The following transcripts of ENSDARG00000041204 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 47062259)
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCCCTTCCMAACATCACCCTGGGTCTGCCAGCCACCGGCCCYTCCAGCG[T/C]GAGTCTATCCTTCCTTCCTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
Long Flanking Sequence:
TTGTAAAAAGCACTACAGAAATCAACATGAATTGAATTAAGCATACCAAAGAAAGCCATTTAGCAGTAGTAAAATACCTGAAAACATCCACTTTAATGGCTCTCCTGTGTTTCTAAATTAACCTCTAAATATCTTCATCTTCAGGACACATTTTGTCAGTTTTCTTGGAGGTTGCACTTGTCATGTTGCTTTTGGAAAAAAAGTTCAATGTTTTTTTTTTTTCCTGGCCAATTCCATGCATGTTTTTCAGACGTGGACAGTCTGCTTCTGTAGACGTGTCCCACAGGGGTCCGGACAGCAACCAGACAGAGCTGTTTGTTTTTATCGCTGGGGTTTATTTATCTGTGCATATGTTTGTGTGTATGTGTGTGTGTCGTTCCAGCCATCGTTGGCACACAGACTCACGGGCAGAGAGGGTCCTGTTAGCCAGCTGTCTCTGTACACATCGCCCTCCCTTCCAAACATCACCCTGGGTCTGCCAGCCACCGGCCCCTCCAGCG[T/C]GAGTCTATCCTTCCTTCCTTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTTTCTCTCTCTCTCTCTGTTTTTCTCTCTGGACCGTCAGGGTGCCACATATGGCTTTTCAGCACCAGTGCCGTTTTAGAAAGAGTCTTTTGAGAAACAATGGCTGACCAGAGCTCATTGACGCAGGCAGAAAGAATGATGAATGAAAGGGGAGGGATTAAAAAAATGAGGAACACTTCAGTTCAAGTTACAATTCACACCATTTACTCTGGTGGTTAATTTTTCTGGTTTTTATTTTTTTATTTTAACTACTTGTTTAAAATGAGCCGAGTTGTTTGGATCAATTTAATTGTTTTATGTTACATCCACTTAAATTTATAAAAATGATTAAGTTAGTTTTGTTGATTTGGTTTGGGACAAGTGTACACTGTAAAAAAATGCAGGGTTCCAAACAATTCCATTATCTTGTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14812
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036277 Essential Splice Site 537 1023 11 25
ENSDART00000124870 Essential Splice Site 537 1023 11 25
ENSDART00000127567 Essential Splice Site 539 1026 10 25
ENSDART00000135537 Essential Splice Site 364 850 7 21

The following transcripts of ENSDARG00000041204 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 47043976)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 46175256
GRCz11 9 45975735
KASP Assay ID:
2260-2490.1 (used for ordering genotyping assays)
KASP Sequence:
ACTTTCAGCAGAGAGAGAGRCAAGCGGAGGAGGAGCTGCTCTTCAGACAG[G/A]TGAAACTCTATTTGCATTACACACACACAAGCACACACCAGTCAAATRAC
Long Flanking Sequence:
TTGGCTAGCTAATGAGTGTAGATGAGTGGCCAGCTACAGTCAATCATATCACATGCTCCTCTCGAAATTAGTTTGTGAAACTTCATTAAGCTTCCTTCCAGAAAGAAAAATACCACCCACACATTTTGCATGGTTGTAATAAAACAGCATAATGATAATGTTAACTTTGTTGAATTTCGTTGTACCATGTAAACCATGGTACAAACACTCCACTGAAATGATACATGTTCTACTACAGAAATAAACTTGTTGAAATAAACTGATGGTGAGTTTGTCATGTGTTTCTCTGTCAGATGATGGTGAAACCGAGCGAGCCGAACCGACAGCACGAGAGCCACCCGGAGGAGACAGAAGAGGAGCTGAGGGAGCACCAGGGGCTGGGAGACCCCGCAGACCCTCTTCCTCACGGGGTCACCATTAAACAAGAGCCTCCAGATGAGCAGGACGAAGACTTTCAGCAGAGAGAGAGACAAGCGGAGGAGGAGCTGCTCTTCAGACAG[G/A]TGAAACTCTATTTGCATTACACACACACAAGCACACACCAGTCAAATAACCAGTGAAGTGTGTTTCTCTCAATGGGACTAATTGAAAACCGACTAAACCAGTGAACACTAGAAGGGGGCAGCAACAGGCTATTGTAATCAACTGCAATGTGTCACTCTAACCAAAACCATTGGTTCTAACACAGAGGTAACAGAGGTAGAGACATGCATAATATATGTTTAGATTTATTATGCAATTTTATGAATGCCTTAATCTTTAAACCAATGGTGTATGTATATGTATTTATACAACAGTTCTGTCTGGTTCTCGAATCTGATTGGCTGATAGCCGTGATATATTTAAGTAATATCAGCACCCATACAGCCTCTTTACCCTTTGTGTATTACTCCACCCACATACAGCCAGCAAAAAGCAGACATATACAGATCTAAAGTTTAAAAGATGCTTGCTCAGCTGTTTAACTGTCAGCTCATGATTTGAATCCAACGCGGAAGAAAGTA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa27480
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000036277 Essential Splice Site 679 1023 14 25
ENSDART00000124870 Essential Splice Site 679 1023 14 25
ENSDART00000127567 Essential Splice Site 681 1026 14 25
ENSDART00000135537 Essential Splice Site 506 850 10 21

The following transcripts of ENSDARG00000041204 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 47030485)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 46161765
GRCz11 9 45962244
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCCATGTGCTGCTTTATGGAACCAACCCTCTCAGACAGAAACTGGACAG[T/A]AAGAGAACACACACACACACACACACACACACACACACACACACCTGAAT
Long Flanking Sequence:
AAATAATCAAGCATCAAATCATCTTGTTTGAAGGATTCTGAAAGTGTGTGGCTGGAAAATGTCACTTTTCATGACAAGCGTTAGTTACATTTTAAACATCTTTTAAAAGAAAACAGTTTTGTTTAATTCATAGTAAGTTTTGGTTCAAACAGATTTACCCATGGTCAGCATAAAATACTTACAAATAAATGTAATAGAAATGTTACAAAAAGAAATATGAAAAGATGAACTATAGTATCTAGCTGGATATATTCAATTTGAAGTTTCAACACATGTTTCAGTTGATACTTGATAGCTGAATCTCCAATTTATCCACTTCAAAATGAATGTATCATCTTCCTTAGCTCTTAAGTCATTCTGTTTTATTATTATTTTTATTTGTTTATTTTTTTGCAGTGTATTCGAGGCAGGAAAGCCACTCTGGAAGAGCTCCAGACAGTCCACTCTGAGGCCCATGTGCTGCTTTATGGAACCAACCCTCTCAGACAGAAACTGGACAG[T/A]AAGAGAACACACACACACACACACACACACACACACACACACACCTGAATCAGAATGAGGGTTGTGAATGAGCGCTTTGTTATATATCTCTCTCTGCGACATTTGGAGGCTGATGATGGCCCTCTCAGTTATTAGCTCTACGCCTGGACTTGTGCAATTATCCACATTATTTACGCTTCTGCAGCCAGATCCGCCTTACAGCATGTTTCCTAAACGCTGCAGTTTGTTTCATTTCCTGTTTTGGCCCGTCATCATTCCCTCTCCGACCTAAACTCCCCAGCGTTCGGCCCACTCTCCGCTTTCATCAGTCATGGCCTTGATCTGAATCTGCCCCTGAGCTGTCCGTCAAAAGCGTCACCTCTCTGCCAATAACAACCACACATGCAGTTTTCCATGACTTCAGCTCCGGCCCCCTCATGCAGCCATCAAACACATGCTTAAAGGACATGCCTGCTCGCACATGCACACGCACGCATGCATACATGCACACAAATATACAT
Associated Phenotype:
Not determined