Busch Lab

ZMP

suv420h1

Ensembl ID:
ENSDARG00000041081
ZFIN ID:
ZDB-GENE-041114-22
Description:
Histone-lysine N-methyltransferase SUV420H1 [Source:UniProtKB/Swiss-Prot;Acc:Q5U3H2]
Human Orthologue:
SUV420H1
Human Description:
suppressor of variegation 4-20 homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:24283]
Mouse Orthologue:
Suv420h1
Mouse Description:
suppressor of variegation 4-20 homolog 1 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:2444557]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa36641 Essential Splice Site Available for shipment Available now
sa23293 Nonsense Available for shipment Available now
sa36642 Nonsense Mutation detected in F1 DNA Not yet available
sa18386 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa36641
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060191 Essential Splice Site 52 808 None 10
ENSDART00000123099 Essential Splice Site 52 808 None 9
Genomic Location (Zv9):
Chromosome 18 (position 20895418)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 21125641
GRCz11 18 21114707
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATCTTCGCCAGAACAAAGGCTCCCCGAGTGTCAGAAGATGCAGTCGACG[T/G]AAGTTCATAAAACAATTTATTGTATTTTACCAGTAGTTAGTTTTTCTATT
Long Flanking Sequence:
CCAAAAGTAGCCACGTGGTGGCGCTATGCACCTAAGAATAATTTAAAAGTAATCATCTCAAACATTTGAAGTGAATTCATAGTTCATGGCATGCTGGTAATGAAATGAACCTGTACTGTTTGTGTTGAAGTTGTTGAAGTATTATTGGCAATATAATCATATCAAAAGTACATTAAACAACGTTTTTTTTTTTTTGAACAGGTGAAGTCAAATCTAAAGAAACAATTAAAGACGACAGATCTGACCTTATTCCCATTGTACCTGTCGCTGTCTTGTTGAATGGTTTCTCACAAGCACACAGAAGCTCAATGCGCCTTCTCCATACCGCCAGCTGGTATGAAGTAGATGGGAGAATCCAAGAACATGGTGCTGAATGGCAGGAGACATGGCAGAAAGTTCTCCAGTAATCAGCCCGTAAGCAAATCCAGGCTGCAAAACACACAGAGATCCCATCTTCGCCAGAACAAAGGCTCCCCGAGTGTCAGAAGATGCAGTCGACG[T/G]AAGTTCATAAAACAATTTATTGTATTTTACCAGTAGTTAGTTTTTCTATTAGTTATTCATGTCAAATGTTCAAACAGGTTGTGGTGGGGCGCCCCCGGAGGCAGAAAGGCGTCATGTTCCTTCATCGGGAATGACTGCCAAGGAGTTGTGCGAGTATGATGATCTGAGCACCAGTCTGATCCTGGATCCATACCTTGGCTTTCAGACCCACAAGATGAACACCAGGTTTGTGCTTGGTGAATTTGAAAATGGTATTTTACAGTTAACAAGAGTTTTTTTATTTATTTATTTTTAATACATATATTTTTAAGGTTTCGACCAATCAAAGGCCGGCAGAGGGAGCTGAGGGAGATCATTGAGCTTTTCAAGAAGCATGACAACCTGGAGAAAGCTTTTCAGGCTCTGACATCTGGAGACTGGACCAGACATCATTTTCTCAACAAGACCAAGTCCCAGGAGAAGCTCTTCAAAGCACATGTAAATTTTAGCTAATGAATATT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa19200
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060191 Essential Splice Site 255 808 7 10
ENSDART00000123099 Essential Splice Site 255 808 6 9
ENSDART00000060191 Essential Splice Site 255 808 7 10
ENSDART00000123099 Essential Splice Site 255 808 6 9
Genomic Location (Zv9):
Chromosome 18 (position 20897276)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 21127499
GRCz11 18 21116565
KASP Assay ID:
2261-2146.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTAATATTATTATTTTAATTTCTTACAGATTGCAGGCCAAACTGCAAGG[T/C]AAGTACATGTGATTGGACTCTGCTTTCTCAATAATGAAGATTAATGAGGA
Long Flanking Sequence:
ATATATATATATATATGTATATATATATATATATGTATATGTATATATATGTATATATATATATGTGTATATATATATATATATATATATATATATATATATATATATATATATATATGTATATATATATATATATGTCAAATTGTCAACTTCATTTGCTGCTGGTTTTCATCATATGCTTTTTATTTGCACATTTCAGGAAAAGGAATGATAAAATCGAACATCTTGTGGGCTGTATTGCTGAGTTGTCTCCCAGTGAAGAGCGGATGTTGCTTCGACATGGAGAGAATGATTTCAGTGTCATGTACTCAACGCGCAAAAACTGCGCACAGCTCTGGCTGGGACCTGCAGCTTTTATTAACCACGGTTTGTCTCTTCTAGATTCTGATCAATATGATGTGATCAATAAAAAATTTCCAATTATCATATGTTGTCCTTAATAATAAAAATATTAATATTATTATTTTAATTTCTTACAGATTGCAGGCCAAACTGCAAGG[T/C]AAGTACATGTGATTGGACTCTGCTTTCTCAATAATGAAGATTAATGAGGAATGGAAAATACAGTTTTGCTGATGTGTGGCATTTGTTCCAGTTTGTGTCAACAGGCCGAGATACCGCCTGTGTAAAGGTTCTACGGGACATTGAACCAGGGGAAGAGATCTCCTGCTACTATGGAGATGGATTCTTTGGAGAAAACAATGAATTCTGTGAATGCTATACTTGTGAAAGGTATCATGTGCTGCATTCCTTTAGTTTCTCGGGTTTCTTTGTGTGTTGTTGGTGGGAATTAGAAACAGCAATTCATATCATATTTTTAAATAATTATGCAAAGAAATGGTTTGTTTTGACATGCATATGCTTGATGTAGAAATTAATATGCAAATATGAATATGTAAAATTCAGCACTCTTTACACTTTAAAACATTTTCTTGTGTATGATGATAATGATGATGATAATATTAATACTAATAAAATGCCATGTTTTTATACACCCTTATGTT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa7856
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060191 Essential Splice Site 255 808 7 10
ENSDART00000123099 Essential Splice Site 255 808 6 9
ENSDART00000060191 Essential Splice Site 255 808 7 10
ENSDART00000123099 Essential Splice Site 255 808 6 9
Genomic Location (Zv9):
Chromosome 18 (position 20897276)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 21127499
GRCz11 18 21116565
KASP Assay ID:
2261-2146.1 (used for ordering genotyping assays)
KASP Sequence:
ATTWAYATTATTATTTTAATTTCTTACAGATTGCAGGCCAAACTGCAAGG[T/C]AAGTAYATGTGATTGGACTCTGCTTTCTCAATAATGWAGNNNNATGAGGA
Long Flanking Sequence:
ATATATATATATATATGTATATATATATATATATGTATATGTATATATATGTATATATATATATGTGTATATATATATATATATATATATATATATATATATATATATATATATATATGTATATATATATATATATGTCAAATTGTCAACTTCATTTGCTGCTGGTTTTCATCATATGCTTTTTATTTGCACATTTCAGGAAAAGGAATGATAAAATCGAACATCTTGTGGGCTGTATTGCTGAGTTGTCTCCCAGTGAAGAGCGGATGTTGCTTCGACATGGAGAGAATGATTTCAGTGTCATGTACTCAACGCGCAAAAACTGCGCACAGCTCTGGCTGGGACCTGCAGCTTTTATTAACCACGGTTTGTCTCTTCTAGATTCTGATCAATATGATGTGATCAATAAAAAATTTCCAATTATCATATGTTGTCCTTAATAATAAAAATATTAATATTATTATTTTAATTTCTTACAGATTGCAGGCCAAACTGCAAGG[T/C]AAGTACATGTGATTGGACTCTGCTTTCTCAATAATGAAGATTAATGAGGAATGGAAAATACAGTTTTGCTGATGTGTGGCATTTGTTCCAGTTTGTGTCAACAGGCCGAGATACCGCCTGTGTAAAGGTTCTACGGGACATTGAACCAGGGGAAGAGATCTCCTGCTACTATGGAGATGGATTCTTTGGAGAAAACAATGAATTCTGTGAATGCTATACTTGTGAAAGGTATCATGTGCTGCATTCCTTTAGTTTCTCGGGTTTCTTTGTGTGTTGTTGGTGGGAATTAGAAACAGCAATTCATATCATATTTTTAAATAATTATGCAAAGAAATGGTTTGTTTTGACATGCATATGCTTGATGTAGAAATTAATATGCAAATATGAATATGTAAAATTCAGCACTCTTTACACTTTAAAACATTTTCTTGTGTATGATGATAATGATGATGATAATATTAATACTAATAAAATGCCATGTTTTTATACACCCTTATGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23293
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060191 Nonsense 280 808 8 10
ENSDART00000123099 Nonsense 280 808 7 9
Genomic Location (Zv9):
Chromosome 18 (position 20897442)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 21127665
GRCz11 18 21116731
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCTGTGTAAAGGTTCTACGGGACATTGAACCAGGGGAAGAGATCTCCTG[C/A]TACTATGGAGATGGATTCTTTGGAGAAAACAATGAATTCTGTGAATGCTA
Long Flanking Sequence:
TTTCATCATATGCTTTTTATTTGCACATTTCAGGAAAAGGAATGATAAAATCGAACATCTTGTGGGCTGTATTGCTGAGTTGTCTCCCAGTGAAGAGCGGATGTTGCTTCGACATGGAGAGAATGATTTCAGTGTCATGTACTCAACGCGCAAAAACTGCGCACAGCTCTGGCTGGGACCTGCAGCTTTTATTAACCACGGTTTGTCTCTTCTAGATTCTGATCAATATGATGTGATCAATAAAAAATTTCCAATTATCATATGTTGTCCTTAATAATAAAAATATTAATATTATTATTTTAATTTCTTACAGATTGCAGGCCAAACTGCAAGGTAAGTACATGTGATTGGACTCTGCTTTCTCAATAATGAAGATTAATGAGGAATGGAAAATACAGTTTTGCTGATGTGTGGCATTTGTTCCAGTTTGTGTCAACAGGCCGAGATACCGCCTGTGTAAAGGTTCTACGGGACATTGAACCAGGGGAAGAGATCTCCTG[C/A]TACTATGGAGATGGATTCTTTGGAGAAAACAATGAATTCTGTGAATGCTATACTTGTGAAAGGTATCATGTGCTGCATTCCTTTAGTTTCTCGGGTTTCTTTGTGTGTTGTTGGTGGGAATTAGAAACAGCAATTCATATCATATTTTTAAATAATTATGCAAAGAAATGGTTTGTTTTGACATGCATATGCTTGATGTAGAAATTAATATGCAAATATGAATATGTAAAATTCAGCACTCTTTACACTTTAAAACATTTTCTTGTGTATGATGATAATGATGATGATAATATTAATACTAATAAAATGCCATGTTTTTATACACCCTTATGTTTTAATTTTTAGCCAGTGTTTGAACTTAGTGAGTTAAGATAATAAAAATTTGATAAAAAAAAATCATAGGTTGTGACCAAAAAAAGTGCTTTTCCATCAAATTAAAAGTTGTCATTTTTTAATAAATAAATAAAATTAGGAAGAAAATTCTAATAATATAATAAATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36642
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060191 Nonsense 366 808 9 10
ENSDART00000123099 Nonsense 366 808 8 9
Genomic Location (Zv9):
Chromosome 18 (position 20898337)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 21128560
GRCz11 18 21117626
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTCTGTCAGTTCCAATGCAGAGGCAGACTCTCAGGAACCAACCACTGTA[C/T]AAACATGTGAGAGACCTGTAATACCAGACGTTTGATGCTAATAATACTGT
Long Flanking Sequence:
AATCATAGGTTGTGACCAAAAAAAGTGCTTTTCCATCAAATTAAAAGTTGTCATTTTTTAATAAATAAATAAAATTAGGAAGAAAATTCTAATAATATAATAAATCAATAGAAAATAAAAATTCAAGTGGTCTCTTCATTTTTTTCCCACCAAACCTGTATGAAATATATTTGGCAATAGTGTTTATAAGCATAACCTTGTTGCTTTATTTTGATATATAATCTATTTGGTATTATACACTGTCACATAATTGGATCGAATAGTCATCTATTAAATGACATTTTTAAATGAAATATTTATGTTTCAGGCGTGGCACTGGAGCTTTTAAATCGAAACCAGGGTTACCTGTTGAAGCTCCAGTGATCAATAGCAAGTACGGCCTCAGAGAGACAGACAAGCGTCTGAACAGACTGAAGAAGCTGGGGGAAAGTTGCAGGAACTCTGACAGCCAGTCTGTCAGTTCCAATGCAGAGGCAGACTCTCAGGAACCAACCACTGTA[C/T]AAACATGTGAGAGACCTGTAATACCAGACGTTTGATGCTAATAATACTGTTACGGCTCAAGCTCATCATTTCTTTTCTCTTTCTTTCATGTTTCTCCAGCATTACGTAAGAGAACTTCACAGTCCTGTGTCAAAAAGCACGGAGAAGCTAAGGCTGTAACAAGGCAAACTCTGTCAAGCACTCCTTCTTCTACCTCATCCTCTAAACGAAGTCAAGCGAATATTTCAAGTTTACCAAAGAGACTTAAGTCAAAGCCCACACAGACTTTGTCTAAAGGAAGACGACGCTGTCGAGGCCTATGGACGAAAGGTTCTAGCCGAGTGAGCGCTAGCGGAAATCTCAAAGAGTCCTCTAGACGAGACACAGACAGACGTAGATCTGCAAGCAAAGGCAGTGTTGCGCGTTCATCAGAAAACAATCGGAGCTCTTCAAAGGGTGCTTCCCCATGCAAGGACAGCACACTTTGCCCTTACAGAACTCGTAGGTCCACGAGGACTTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18386
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000060191 Nonsense 625 808 10 10
ENSDART00000123099 Nonsense 625 808 9 9
Genomic Location (Zv9):
Chromosome 18 (position 20899207)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 21129430
GRCz11 18 21118496
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCTCTAAGAGCAGCAAGRCCCTCCGTCGAGGGAAAGGCAAGAAGAARCGA[C/T]AGATCACAYGCTATGACGCTCAGCTGATTCTGCAGAATAACTCRGGCATC
Long Flanking Sequence:
GACGTAGATCTGCAAGCAAAGGCAGTGTTGCGCGTTCATCAGAAAACAATCGGAGCTCTTCAAAGGGTGCTTCCCCATGCAAGGACAGCACACTTTGCCCTTACAGAACTCGTAGGTCCACGAGGACTTCTCTTGGTGCTCAGGGGGCTGAAGGCACAGAGGCTTCAAACCACCCGGCGAGCCCGAGCATCGTCCTCAAGTCAGAGCCTGGAGAGTTCATTCCTGTGACACTTGGGCACCAGATGAGCACTCCTAGTTTGGACTCCAGCTGTCCCAAGAAAGGGACTTGTCCTAGACGCAGAAGGACAGTAAAACAGGAAGACTCCTACGGCGAGTCCTTCGTCCAGGAGGGCGTTCCAGATCTGCGGCACGCGGTTCGGGCTGCAGATGTAGCAGACTGTGGGAAGGTGGTGCTCGGCCTTCCAGACCGCCACCAGCACTACAACGGCTCCTCTAAGAGCAGCAAGGCCCTCCGTCGAGGGAAAGGCAAGAAGAAACGA[C/T]AGATCACACGCTATGACGCTCAGCTGATTCTGCAGAATAACTCAGGCATCCCCAAGATAACACTACGCCGGCGTCGAGACAGCAGCAGCAGCAAGAATGAGCCCAGAGAGACCAGCTCCTCAAGCTCCTCCAAAATCAGCATCAAGTTCAGCAAGGAGCACGAGAAGGACCGGAGCAGCTCGTACGTAGCCAAACTCAACAACGGCTTCAGCCACGGACCGCACAGCAGCTCCACCAAGCTCAAGATCCAGCTGAAGCGGGAGGAAGACCCCGCCAGCTTGCACCGCACTTACCCGGAGGACGTCACCTTGGGCATCGTGCAACGAGACGCTGCGGACGTCCTGGATCACAAGGCAGCCGCTCAGGTAGGTCAGGACATGGAAGTGGAATCGATGTCGTCAGAGGACGACGACGATGACTACTTTGATAACGAGGATGATTTCATCCCGCTCCCACCAGCAAAACGCCTGCGCCTCATCGTGGGCAAAGATTCCATAGAC
Associated Phenotype:
Not determined