Busch Lab

ZMP

si:ch73-105b23.3

Ensembl ID:
ENSDARG00000040851
ZFIN ID:
ZDB-GENE-081028-42
Description:
Novel protein similar to vertebrate pleckstrin homology domain containing, family H (With MyTH4 doma
Human Orthologue:
PLEKHH2
Human Description:
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 [Source:HGNC Symbol;Acc
Mouse Orthologue:
Plekhh2
Mouse Description:
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 Gene [Source:MGI Symbol

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa11675 Nonsense Available for shipment Available now
sa22227 Nonsense Available for shipment Available now
sa22226 Essential Splice Site Available for shipment Available now
sa6286 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa28066
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Nonsense 53 1455 2 32
ENSDART00000142936 Nonsense 53 178 3 7
ENSDART00000144553 None None 1090 None 23
Genomic Location (Zv9):
Chromosome 13 (position 8244004)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8546524
GRCz11 13 8878547
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTGCTCTCTTAGATGCAGCAGTTGGAGGCCCAGGTACTGGAAGCAGAA[C/T]AACGTGCATATGAAGCCAACCAGCAGGTAAATGCTAAAAATAATGAATGT
Long Flanking Sequence:
GACATGTCCTGTGGTCTGATGGAAATAAGATTAAACTGTTTGGCCATAATGACCATTGTTACATTTGGAGGACTAAGGGTAAAGTTCACAAACGCAATTCACAAACGTGTATTGAACCGTGGATGTTGTACCGAACGGTTGTAAATTTTGTTAATTTTGTACCGAAATTAAGAATTGTGGCATCCCCACTTGGCACATATTGGCACCTACTTGGCACATATTGTATTTATGTTGTTGTATTATTATTTGGCATGCTGCATTTCTGGCATAACAAAATACATATTTTATTTGTATTCCCAGCAGAAAGAGCATGTTTACAAATTCAGCTGATTTTCCCTAGTAACATGCTAAATGTTAGGTATTAAATAGATTTTTTAATAATAATTCTAATGTAGATTCAGTGCATATACAAATATTTGTATAAAGTCATTCCTTCATTTAGTCAAACTTCTTTGCTCTCTTAGATGCAGCAGTTGGAGGCCCAGGTACTGGAAGCAGAA[C/T]AACGTGCATATGAAGCCAACCAGCAGGTAAATGCTAAAAATAATGAATGTATTATTTGCACAGACAGTGATATATTTAATTATAAACAAATATATACAATTGAAGTCAGAATTATTAGCCTTCCTGTATATTTTTGTCCCTCAATTTCTGTTTAACAGAAAGAAGTTTTTTCAACAAATTTGTAAATATAATAGTTTTAATTACTAATTTCTAACAACTGATATCTTTTATCTTTGCCATGATGACAGCACATATTAGTATATTAGATATTTTTCCAGATATTAGTATTCAGCTTAAAGCGTCATTTTAACTAGGTTAATTAGGCTAACTAGGCAAGTTAGAATAATTAGGCAGATGTCACGACACTAGACAGAGAGGATCCAATTGCAAGTTCTTTAATGAAAAATGAAAGAATCTATCAAAGGATACAACTGGATGTTCCGAAGACAAAGAATTGTTCAAAACAAAAGAGATCCACAGGCCACAACGAAGACGTCAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11675
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Nonsense 115 1455 4 32
ENSDART00000142936 Nonsense 115 178 5 7
ENSDART00000144553 None None 1090 None 23
Genomic Location (Zv9):
Chromosome 13 (position 8242148)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8544668
GRCz11 13 8876691
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTAANTCCATTTAAATATGGATATTATTCCATTTTACAGAAACAGAAT[C/T]GAATYCAAGATGCCAGGACTGTGGAAGAAAAAGCAGCCAAAATTAAAGAA
Long Flanking Sequence:
AATATCAAGTAAAATATTATTTACAGTCATCATGTCAAAGAAAAAATAAGTCCGTTGTGAGAAATAAGTTATTAAATCTATTATGCTTAGAAATGTGCTGAAACAATCTTCCCTCCATTAAACAGAAATTGGTGAAAAAAATGAACAGGGGCGGTAATAATTCAGGGGGGCTAATAATTCTGACTTCAACTATATATATATATATAGCAAGTATTGGCATTGTGTGCATGTGTGTTAAAGGTGCAGTGGATGGAAGAGCGTCTAAAGGCATCAGATATCCAGTCAAGTGATTCAGACGTGAGGCTCTTCAGGCGCTGTCAAAATCTTCAGTCAGTTCTGCAGGAGAAAGATGAGCTTATTGCCACTCTAGAAAAACAGCTAGAGGAACAGGTAAATCACACATCCAGTCCAATTTAAAACAATCAGGTTTGCATCGGTGGACATAAGTCTTTTTAAATCCATTTAAATATGGATATTATTCCATTTTACAGAAACAGAAT[C/T]GAATCCAAGATGCCAGGACTGTGGAAGAAAAAGCAGCCAAAATTAAAGAATGGGTTATGCGGAAGCTAAATGCAGTATGTTCATTCTGTTTACACTTGTGCAGTGTCTGTCTGTCTGTTTGTCTGTCTGTCTCTGGTTTTTATAACTAAGGAGGAAATGAAAAGCGAGTGGAGAAAGTGTTTATAAGTTGAATTAATGTCACCAGTCTCTGTTTTAGTTTGAGACAGAGAACACCTCTCTGAGGGATAGGCACCAACAGCTAGAGGCTGAGATTCAAGTCCTGAGAAGACAGCTGCAAGGTATTCATACATGAAATTGCACAGTAGGTGAAAAAACCCCACATTATCAGCTCTGGGGGGAAAACTAACTCTAAACAAAAAACAATCTTCATACTTCATTACATATTTCATTTTAGAGGCATGTTATCAGTAGTTTATAAATAAAACACAAATTATTGTTTTAGTCAAAGCATATACCATACAGATTAATGTCAAATACAA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa42139
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Nonsense 195 1455 6 32
ENSDART00000142936 None None 178 None 7
ENSDART00000144553 None None 1090 None 23
Genomic Location (Zv9):
Chromosome 13 (position 8241372)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8543892
GRCz11 13 8875915
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAATTGTGGGTGAGCCCAAGCGGCTTAGCAGCCTGACTTTTGGCTGTTTC[C/T]AAATCAGAGGGAAGAGTCCTCAGGTACAGACAGGCCCAGAACCATCCCAG
Long Flanking Sequence:
AAGTCCTGAGAAGACAGCTGCAAGGTATTCATACATGAAATTGCACAGTAGGTGAAAAAACCCCACATTATCAGCTCTGGGGGGAAAACTAACTCTAAACAAAAAACAATCTTCATACTTCATTACATATTTCATTTTAGAGGCATGTTATCAGTAGTTTATAAATAAAACACAAATTATTGTTTTAGTCAAAGCATATACCATACAGATTAATGTCAAATACAAAGAATCATTAATAACATTGGTCTCATAAGTTTTTATACATTATTTAAAATAATTCAGTTTTGCTGTAAATACAGTGTTAATCAGTGCTTATACAAAAAATTAGGAAAATATTTGGTCTATGATTTAAAAAAAATCCCTTTTACATTTATATAATATTACTTATAAGTGTCATGTTTTATGTCATGGATGTAGCTATGGATCAGTGCTCTGATGGAACACTCCAGCCAATTGTGGGTGAGCCCAAGCGGCTTAGCAGCCTGACTTTTGGCTGTTTC[C/T]AAATCAGAGGGAAGAGTCCTCAGGTACAGACAGGCCCAGAACCATCCCAGAGAAGCATCAGTACCCTGCAAGAAGGTGATCACATGCATATAGACTGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGTTTGAGTTTTTACCATATAATACATTTTATGCCAACAGTTACTTCAGCTACTTAACTATATATATATATATATATATATATATATATATATATATATATATATATATATATAGCGAGTTGCGAGTATATATACATTGGATGCGAGTTAGCCTACTCGCATCCAATGACTGGCTACCTGGGCTCCACAAACACGACAAATTTCCGACTGCTTTAACTGGCCCTGTTTGAAAGTCAAGTGGTCCTTCCAGACATGTCCCATCTACCAAAGAACTCTTCCACAGCAACCTCTACCAATTACTGAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22227
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Nonsense 611 1455 13 32
ENSDART00000142936 None None 178 None 7
ENSDART00000144553 Nonsense 249 1090 4 23
Genomic Location (Zv9):
Chromosome 13 (position 8235674)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8538194
GRCz11 13 8870217
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGAGGAATTTCAGTCTAATTCTGGAGAGGATGAAAAAGCCCAGACTTCT[G/T]GATCAGAGTCACATAAGAGCCACAGGAGCTCCCACTCCTTTAAGAGAGGT
Long Flanking Sequence:
TTTGTTTTGATAGAAATAGTAAATATAAAAAAAGTATCCAGCATTTTGAAATGTAAAGTCTTTATTTAACTGCATGTGGTTTTGGCTAGAAAATTGAGAGTTTAGAAAAGGCCTTTAAGTATTGGTAAACACTAGTTAGCAATTGAAAAAAATAAACTGTCATTGAATACTAGTGAGACTGTCCTATGCTCTTTCTAGACCACTGCAACGCATCTTCATGCCCCTCCTACATGCTCTACACATCCTTTATCTACAGCAACAACAGTACACCTGTCTTCACCACACACAAAGGGGTAAGAACCATTGAGTGTTTTTAAATTTAGAAGAAAACAAATACTTTTTAAATACGTTTATGAATGCCATGTTTGTTTTTATTTTCATAGAATGTGACTTTGTTAAGCAATAGTACGTGTTCAGAGGAGTCATCTAGTTCTGAAGAGGAGGAGAGCTCAGAGGAATTTCAGTCTAATTCTGGAGAGGATGAAAAAGCCCAGACTTCT[G/T]GATCAGAGTCACATAAGAGCCACAGGAGCTCCCACTCCTTTAAGAGAGGTATAGTACACAAGATTAGGTTGTGATTAAAGAACAGGGTTGCTAACCAGGAAGATGCAAATTGGAATCCTGCAGGTACTATTGGAAGTGCTATTACAATTCTACCTTCGAGCAATAACATTGTTATAATTCTTTTATCTTGATAATGTTGAGGGCATATGGTTTATTTTCAGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGATTGTTGGTTGGTTGGTTGGATTGTTGGTTGGTCGGTCGGTTGGTTGGTTGGTTGGATTGTTGGTTGGTTGGTTGGATTGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGATTGTTGGTCGGTCGGTTGGTTGGTCGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTTGGTCGGTTGGTTGGTCGGTTGGTTGGTTGGTTGGATTGTTGGTTGGTTGGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22226
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Essential Splice Site 819 1455 19 32
ENSDART00000142936 None None 178 None 7
ENSDART00000144553 Essential Splice Site 457 1090 10 23
Genomic Location (Zv9):
Chromosome 13 (position 8228430)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8530950
GRCz11 13 8862973
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCTTGTATGACATTTGTACGTTCATGCATTAATATCAAATTTCCCTACTC[A/T]GTTTCCCCTAGGTCAAATCAAAATGTGGGAGGCCCGTGTGGAGGAAGAAC
Long Flanking Sequence:
AGTCGGCGGTCCATTCCACTGTGGAGACCCCTAATAAATTAGCGACTAAGCCGAAGGAAAATCAAAATACAAAAATATATTAGCAATTACAGGAATAAGGACCCAGTTACAGCAATGAACAGTGAAAAGTGTGTATTTCCAATACAAGGCACAGGTAGATGAATGAGAATTGGTAAGGTCACAAAGTAGAGGCAGGATAAAAATATTGTTTTTGTAGTAAAACAACATTTAAAAATAAACCCACCCTGATCAAAAGTGTTACAGGCTTAATAGTATGCTGGATAATACTGTAATGCATGTCTGTTACTGTAACTGATTGTATCATCTATTGTCTCTTTAAGGTGAAGCATGGCTGCTCTAAGCATGTGTGGTGTGCCCTTTTTGGAAAGACTCTCTACTTTTTCAGAAATCAAGAGGACAAGGTCTTCTGTCTCCTTCAATAAAAAGTAATCTTGTATGACATTTGTACGTTCATGCATTAATATCAAATTTCCCTACTC[A/T]GTTTCCCCTAGGTCAAATCAAAATGTGGGAGGCCCGTGTGGAGGAAGAACATAAGTCATGTGACCTTGCTGAACTCTCTGCTCAACACACCATCTCCGTTCAGTCAGGCAGGCAGGGGTCAACATACCTGCTGATCGACTCGCCTCATGAGAAGGTCATTGTGCCATACTGAGCCAGCGAAGCACATTCAAGTCTCAGAATTTTACAAACAGTCAGGAGCTAACAGCATATTAATGAAAGGAAATAAAATGTACAATAATGTGCTAAAGGGGAATACAAGTTAATGACTGTTATTAGTGTCTTCTTTTAAAAAGTAACATTTTACGTTTGTAAAATTAAAGGTAATATTTAAGGTAATATTTTAAATCACTTTTTACACAAGTACAATTATTGTAATGTTTACTAACATTCTAAAGCAAGAGTGAAATATGTGTGATTTGAACAGTGCTAATTAAATTTTAAATGTACTAATTTCCAGCTTCCTAATAAAATGTGTCATT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa4489
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Essential Splice Site 1147 1455 25 32
ENSDART00000142936 None None 178 None 7
ENSDART00000144553 Essential Splice Site 782 1090 16 23
Genomic Location (Zv9):
Chromosome 13 (position 8219961)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8522481
GRCz11 13 8854504
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGACCCCACTGGCAAAGACCTTGAGCACTGTCTTCAGGGAAACCTGAAGG[T/A]GAGATTCTGACAAAAACRCCATTCAAACAGTACTCTGAGAGCATAGTTTT
Long Flanking Sequence:
ATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATAGATGGACAAACGGATGGATGGATGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGATGGACAAACGGATGGATTGTTGGATGGATTAATATATGGATGGATGGATAGACGGACGGATGAACGGATAGATAGATAGATAGATAGATAGATAGATAGATTGTTTTGTTTTTGGATGAACTGTTCTTTAAAAGTGTTTACTTTGCAAACAGTATGCAATTCAAGCTTATTACTTAAGCTCCATTTGGGTGTGTGTTAGGTTGTCAGTTTTGATGCTTCAACCACAGTGGAGGAGTTTCAGAGTCGGCTGAACCAGGACATGGGCATGAGAAAAACTGGTCAGTCTGGTTTCAGCTTTTATTCTGATGACCCCACTGGCAAAGACCTTGAGCACTGTCTTCAGGGAAACCTGAAGG[T/A]GAGATTCTGACAAAAACACCATTCAAACAGTACTCTGAGAGCATAGTTTTCTTGAAATGAATGTGCTGTGTCCTCAGATTTGTGATGTTATTGCAAAATGGGAACAGGCTTCAAAGGAACAACACAGAGGCAAAGCAGAGATTGCGAGGACTGTTAAACTCACTTATAAAAACAGGTGCAGTATAGATTATTTTACAGAACAAGCAACAGGTTTCAGTTTGGGCCTAATTTCTAGTTTATTCCCTGTAGGTTATACTTCTCCAAACAAGTGAGTGGAGAGACTGAGAGAGAGCGTTTGCTACTGGCATACCAAACAAATGAAGAAATTACAGCTGGTCACTTCCCTGTCAACAAGGAGCTTGCTTTAGAAATGGCCGCCCTGCTTGCTCAGGTACACAGTGCTGATGCTTTGAATATTAGTGGATAAATTTGTAACTTGTGTGAAAATGAAATAAATTATTCCACACTATATTACCAAAGCTTTTTGAGACAACCCTCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6286
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059881 Nonsense 1299 1455 29 32
ENSDART00000142936 None None 178 None 7
ENSDART00000144553 Nonsense 934 1090 20 23
Genomic Location (Zv9):
Chromosome 13 (position 8216417)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 8518937
GRCz11 13 8850960
KASP Assay ID:
554-5455.1 (used for ordering genotyping assays)
KASP Sequence:
TTTCCACACGTTGGGCATCTCTGAGAGGTCAGACTTCATCRGAGTGCATA[C/T]GAATCTACTTGACAGTGGCTCGCAAGTGGTCATTTTTCGGAGCCAAACTA
Long Flanking Sequence:
TATATATTTTATATTAATGTTAAGCACCTTGGGTCTGAGAGTAACGCAATTTCGATTCTCTGTATGTCTTGTACATGTGGCTGAATTGACAATAAAGCTGACTTTGACTTTGACTTGACTTTGATATCCATTACATTTCAATAATTTGTAAATAAAGTATAGGTTTTGAATTAAAGTAAACACTAAATTCTTATTTGTTCAAAACAGGTGGAGTTTGGAGACTTCGAGCACCCATTGTCTAGTCCAGGTGGTTCAGGAAATACTCCGACTAAGTCTAACCAGACCCTGAGACAAGTTCTAGAGCGCTTCTACCCAAAGCATTACCAACACACCTGCACTGAGGAAGAAAATAGGTATTGATGTCTCCGGTGGAAGAAATATGAATACTCAGAGAGAATACTTGTCCATCTTACGCACTGAAATGTTCTCTCAGGCAGCTGATACAGAGGCTTTCCACACGTTGGGCATCTCTGAGAGGTCAGACTTCATCGGAGTGCATA[C/T]GAATCTACTTGACAGTGGCTCGCAAGTGGTCATTTTTCGGAGCCAAACTATTCGAGGCTGAAGTGAGTCTCCTTCCAAGGCTGAATGTGATGTTTGTCTTTTGATGATAATTTAAGAATGATGTGTCATTATTGCTTTATTTATTTCACTCTGTGTCTTCCCATAGACCGTAACTCCATCGGCATTGAAGAATGTGCGAGTTTGGCTGGCAGTACATGAAGATGGAATCAGTGTGCTGGAATTCAACGCAATAGTAAACACATTCACTTGAGAGCTTTGGAGGTCACATTAATCAAGTTAATAAAGAGCTGAGCAAAGTCTTTACCTTTTGTTTTTACTAGAAAGTGCTTGCATCCTACCCTTATAAAAGCATTGTGACGTTTGGAGTTTGTGGTGAAGATTTTAAACTGGTAGTAGCAGAGAGTTCTGGCTCTGGCACATCCAAAGGGAAGCATCTGTTTGCCATGACCTCATCTAAGGTAGGTGCTCTTAAAAAAAAC
Associated Phenotype:
Not determined