Busch Lab

ZMP

adra2a

Ensembl ID:
ENSDARG00000040841
ZFIN ID:
ZDB-GENE-021010-1
Description:
Alpha-2A adrenergic receptor [Source:UniProtKB/Swiss-Prot;Acc:Q90WY4]
Human Orthologue:
ADRA2A
Human Description:
adrenergic, alpha-2A-, receptor [Source:HGNC Symbol;Acc:281]
Mouse Orthologue:
Adra2a
Mouse Description:
adrenergic receptor, alpha 2a Gene [Source:MGI Symbol;Acc:MGI:87934]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa43873 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa45776 Nonsense Mutation detected in F1 DNA Not yet available
sa24199 Nonsense Available for shipment Available now
sa39378 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa43873
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059869 Essential Splice Site None 388 1 2
Genomic Location (Zv9):
Chromosome 22 (position 32276130)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 29637260
GRCz11 22 29586455
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTAGATGCCTTAATAAGTTTGTGGAAAGCTTCAGGCTTATTTCATTAAG[G/A]TAAGGTACATCCCTGTCTTACTTTTTTTTTGGTTGTGTAATTTTGTGGTG
Long Flanking Sequence:
GTTATGTTGTCTTCTCCAAGTAAAAGATAGAGCAAATAAACGTTTTTATTGGTTTAAACCACTCAGAAACATACAAAAAGTTATTTATTTATTAATTTTTTGGCGTTTTTACAGAGCCTCTCAAGGCTGCTGCTTAGCAACGTCAATCGGAGGCTGGAGTTAAGAGAAAGTGGGCGTGGCTCAGAATAGTCATTATTATAATTTCCTGTGCGCGTCTCCCACAACACACACACACACACTCCAGCGCGCTCACGGCAAGCTAAAGTGATCACGCCTCTATTAGCTGTGCGCGCTCACGGCAGATCCTGCGCGCGCACAGCCGAGTCGAGCGCTGATGATGATGATGCGCGGTCTTCACACGCTCCATCGACGAGATGCGAGAGATTAACCATGCAGTTTTTCTCATGCTGAGCGACTTTAAACAGAGAAGTTGCACTCCGAGGGACGTTTCTTAGATGCCTTAATAAGTTTGTGGAAAGCTTCAGGCTTATTTCATTAAG[G/A]TAAGGTACATCCCTGTCTTACTTTTTTTTTGGTTGTGTAATTTTGTGGTGTTTTATATAAGAGTGAGAAACAAATGTATAGTTTTACCATAATTATTTAAATGTTTGAAATTAGTGTAATTGTTTTGTTTAATTACAATCAATTGCTTGTAAAATAAAACTTTGCATCTGTATGTTGTGTGTACTGTGTATGTTATGTATAAACTTGATAAAAACATGTTTATATATAATGCAAAATATATGTTAATACATTTGTTTAATATATATTTAAAATTTTTACTTGTTTATTATTGTTGTAGCCTATATATACACAATAAACATACAGTACACATTTCATCTATTTTCATCTAATAATACATTTTCCAATTTCTTTTTAGATGTCAGAATGATTAGAATCGTCTCTGTTTGTCAGTAATATGGAAAAAGTGAAGTGTCATCAACCAAAAACATAATTTCACTCGTGTGGAGAAGAGACTGTAACTGTCAGCTATGATTTGTGGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45776
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059869 Nonsense 80 388 2 2
Genomic Location (Zv9):
Chromosome 22 (position 32275403)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 29636533
GRCz11 22 29585728
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTGGCCTCAGCTGACATACTGGTGGCCACTCTGGTGATGCCGTTCTCAT[T/A]GGCGAATGAGCTGATGGGTATGTGGACGTTTGGGGGAGTTTGGTGTGAAA
Long Flanking Sequence:
TAATGCAAAATATATGTTAATACATTTGTTTAATATATATTTAAAATTTTTACTTGTTTATTATTGTTGTAGCCTATATATACACAATAAACATACAGTACACATTTCATCTATTTTCATCTAATAATACATTTTCCAATTTCTTTTTAGATGTCAGAATGATTAGAATCGTCTCTGTTTGTCAGTAATATGGAAAAAGTGAAGTGTCATCAACCAAAAACATAATTTCACTCGTGTGGAGAAGAGACTGTAACTGTCAGCTATGATTTGTGGGGCCAATGCAACCAATGGGACCAATGCAACAAAGGAGTACACCCTGCTGGTGGCCCTACCACTGAGCGTTGCAGTGGGGCTCCTCATCCTCCTCATCATCTTCGGCAATGTCCTGGTGATCATCGCCGTGTTCACGAGCCGAGCACTCCGGGCTCCCCAGAACCTCTTTCTGGTCTCGCTGGCCTCAGCTGACATACTGGTGGCCACTCTGGTGATGCCGTTCTCAT[T/A]GGCGAATGAGCTGATGGGTATGTGGACGTTTGGGGGAGTTTGGTGTGAAATCTACCTGGCCTTGGACGTTCTTTTCTGCACAGCTTCAATTACTCACCTGTGCGCCATCAGTCTGGACAGGTACTGGTCAATTACGCAAGCCATCGAGTACAACCTGAAGCGAACACCGCAACGTATTAAGCGTATCATTTTTATCGTTTGGATCATCGCCGCCGTGATCTCCTGCCCCCCTCTTATAACAATGAAGAAATCTGAGGGGGATATCTGTGACATCAATAAGGAAAAATGGTACATAGTCTCATCTTGCATTGGCTCGTTTTTCCTGCCTTGCATCATCATGGTCCTCGTCTACATCCGGATCTATCAAATTGCCAAGAAGAGAACTAGAGCACCTCCTGGGGACCACAGGAAAAACGAAGTGGGAAAGAAGGAAAACGACCCGCATGAGAAGCTCAATGGAATTCAGAATGCAGAACCGGACGACAAGGATGAAATAAATG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24199
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059869 Nonsense 130 388 2 2
Genomic Location (Zv9):
Chromosome 22 (position 32275252)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 29636382
GRCz11 22 29585577
KASP Assay ID:
2261-6996.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCGCCATCAGTCTGGACAGGTACTGGTCAATTACGCAAGCCATCGAGTA[C/A]AACCTGAAGCGAACACCGCAACGTATTAAGCGTATCATTTTTATCGTTTG
Long Flanking Sequence:
TGTCAGAATGATTAGAATCGTCTCTGTTTGTCAGTAATATGGAAAAAGTGAAGTGTCATCAACCAAAAACATAATTTCACTCGTGTGGAGAAGAGACTGTAACTGTCAGCTATGATTTGTGGGGCCAATGCAACCAATGGGACCAATGCAACAAAGGAGTACACCCTGCTGGTGGCCCTACCACTGAGCGTTGCAGTGGGGCTCCTCATCCTCCTCATCATCTTCGGCAATGTCCTGGTGATCATCGCCGTGTTCACGAGCCGAGCACTCCGGGCTCCCCAGAACCTCTTTCTGGTCTCGCTGGCCTCAGCTGACATACTGGTGGCCACTCTGGTGATGCCGTTCTCATTGGCGAATGAGCTGATGGGTATGTGGACGTTTGGGGGAGTTTGGTGTGAAATCTACCTGGCCTTGGACGTTCTTTTCTGCACAGCTTCAATTACTCACCTGTGCGCCATCAGTCTGGACAGGTACTGGTCAATTACGCAAGCCATCGAGTA[C/A]AACCTGAAGCGAACACCGCAACGTATTAAGCGTATCATTTTTATCGTTTGGATCATCGCCGCCGTGATCTCCTGCCCCCCTCTTATAACAATGAAGAAATCTGAGGGGGATATCTGTGACATCAATAAGGAAAAATGGTACATAGTCTCATCTTGCATTGGCTCGTTTTTCCTGCCTTGCATCATCATGGTCCTCGTCTACATCCGGATCTATCAAATTGCCAAGAAGAGAACTAGAGCACCTCCTGGGGACCACAGGAAAAACGAAGTGGGAAAGAAGGAAAACGACCCGCATGAGAAGCTCAATGGAATTCAGAATGCAGAACCGGACGACAAGGATGAAATAAATGGTGTGGACATGGAGGAATCCTCCTCCTCAGACCACAAGGTCTCCAATCCTTGCTCCCTCAAGAAGAAAAGCTCAAAAGGAAAGACCAAGTTGAGCCAAATCAAACCAGGCGATGGAGACAAAACCGAGGCCTGCCAGACTACCAAAGCAAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39378
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059869 Nonsense 277 388 2 2
Genomic Location (Zv9):
Chromosome 22 (position 32274812)
Other Location(s):
Assembly Chromosome Position
GRCz10 22 29635942
GRCz11 22 29585137
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCCAATCCTTGCTCCCTCAAGAAGAAAAGCTCAAAAGGAAAGACCAAGT[T/A]GAGCCAAATCAAACCAGGCGATGGAGACAAAACCGAGGCCTGCCAGACTA
Long Flanking Sequence:
TACTCACCTGTGCGCCATCAGTCTGGACAGGTACTGGTCAATTACGCAAGCCATCGAGTACAACCTGAAGCGAACACCGCAACGTATTAAGCGTATCATTTTTATCGTTTGGATCATCGCCGCCGTGATCTCCTGCCCCCCTCTTATAACAATGAAGAAATCTGAGGGGGATATCTGTGACATCAATAAGGAAAAATGGTACATAGTCTCATCTTGCATTGGCTCGTTTTTCCTGCCTTGCATCATCATGGTCCTCGTCTACATCCGGATCTATCAAATTGCCAAGAAGAGAACTAGAGCACCTCCTGGGGACCACAGGAAAAACGAAGTGGGAAAGAAGGAAAACGACCCGCATGAGAAGCTCAATGGAATTCAGAATGCAGAACCGGACGACAAGGATGAAATAAATGGTGTGGACATGGAGGAATCCTCCTCCTCAGACCACAAGGTCTCCAATCCTTGCTCCCTCAAGAAGAAAAGCTCAAAAGGAAAGACCAAGT[T/A]GAGCCAAATCAAACCAGGCGATGGAGACAAAACCGAGGCCTGCCAGACTACCAAAGCAAGCAGATGGAAGGGCCGTCAAAACCGAGAGAAGCGGTTCACATTTGTTCTGGCGGTGGTCATAGGCGTGTTCGTCATTTGTTGGTTCCCGTTCTTCTTCACCTACACATTCACAGCGTTTTGTGACTGCTGTGTGCCTGAAACACTTTTTAAGTTCTTCTTCTGGTTCGGCTACTGCAACAGCTCCCTCAATCCCATTATATACACTATCTTCAATAACGACTTCCGAAGATCCTTTAAAAAGATCCTCTGCCGGAGAGATAAGAGGAGAGTGGTGTGAACGGGCTGCTGTGTTGTCCGTTTCTCTATCAAATGTAATATATCACCTGCAGTTTACGGGAAGCACTTGTTTACAGTAAGCCAACATGTTGTGTGTCATTATACAACAAGTCCAAGCGGGGCTAAAAATAAAAAAAGACTTTCACATTCTTTGTACAAATGCA
Associated Phenotype:
Not determined