Busch Lab

ZMP

gps1

Ensembl ID:
ENSDARG00000040650
ZFIN ID:
ZDB-GENE-041111-240
Description:
COP9 signalosome complex subunit 1 [Source:RefSeq peptide;Acc:NP_001071227]
Human Orthologue:
GPS1
Human Description:
G protein pathway suppressor 1 [Source:HGNC Symbol;Acc:4549]
Mouse Orthologue:
Gps1
Mouse Description:
G protein pathway suppressor 1 Gene [Source:MGI Symbol;Acc:MGI:2384801]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa45144 Nonsense Mutation detected in F1 DNA Not yet available
sa33237 Essential Splice Site Available for shipment Available now
sa11784 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa45144
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059506 Nonsense 168 487 5 14
ENSDART00000141106 Nonsense 171 490 5 14

The following transcripts of ENSDARG00000040650 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 36240795)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 36112079
GRCz11 3 36241677
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGTCCTGCGTGTGTTCAGGAGGGGTCACGATGACCTTGGAGATCACTA[T/A]CTTGACTGCGGTGACCTCAGCAATGCCCTGAAATGCTACTCCCGAGCCAG
Long Flanking Sequence:
AGCTACGAGTGGAAGCACTGAAGATGGCCCTGTCCTTTGTCCAAAGAACCTTTAATGTTGATGTCTATGAAGAAATCCATCGCAAACTCACTGAAGCCACAAGGCAATTCCTGTTTTATTTTCCCCTCCATGCTTAACATTGAATCCTAATATGGAAAAACAAGCATGATTTTTACTAAGTCTGAATTTTAAACTCTGTTTCACCACAGGGAAGTGCAAGGAGTCCCAGATGCGGTACCAGAGGGGGCAGTTGAACCCCCTCCTCTCGACACAGCCTGGGCAGAATCTACCAGGAAAAAAGCCCTGCTCAAACTGGAGAAGCTGGATACTGACCTTAAAAACTATAAGGGAAACTCCATCAAAGAAAGCATAAGGTATGCCATACTAGTTGTCTCTTTCTCATTAGTATTATTTCCAATTATTGTTTAGCTGTTGTATTGAATATCTGAACATGTCCTGCGTGTGTTCAGGAGGGGTCACGATGACCTTGGAGATCACTA[T/A]CTTGACTGCGGTGACCTCAGCAATGCCCTGAAATGCTACTCCCGAGCCAGAGACTACTGCACTAGCGCCAAGCATGTCATCAACATGTGTCTTAATGTAATCAAGGTGCGGACTCATCTTCCTACGTGGTCATTATCTGGTTTATTGGTTCATTTTATTCAATATTACTCTTCAGTAGTTATAAATTTACCCACATCAAAAATAAATAAGTATTTTTTCATGTGGGTATCTTGAAAGGTACATTTACTACCTTTTTGATCCAATTGCAATGTTATAACATTTTACATCAAAAACATTATAATTTGAGATTAAAGGCTGTTTTCTGTCCTTTTCTAAATGCCATCATCAGAACACACTCTTTAAATAGGAGGGATTGATGGTAGACTCAATGGTAAACGTCCATTGATGTAAATGTCTAATAGTTTGCATGTTGGAAAGGACCACTGAGGTAAACCTATGCATGTATATATGACAGCATACAACTGCTGTGATTTTTAGAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33237
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059506 Essential Splice Site 310 487 9 14
ENSDART00000141106 Essential Splice Site 313 490 9 14

The following transcripts of ENSDARG00000040650 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 36238482)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 36109766
GRCz11 3 36239364
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGCTACGTTTGACAGACAGGAATTGCAGCGAAATGTCATCTCAAGCAGG[T/C]GAATTTAAATGTTTAGCATTTGCAGTCTCTTTATATATGAGGTATATTTT
Long Flanking Sequence:
CAAGCCAATTGATTTGAAGAATTGATACAAATTATAAAGATTAAAAATGATGATGATTTAGTATTTTGGGGGCTGTGATGTGATCGTAAAATAGCCTTTTAATATGGCATTGAATACATTTACTGGTGTTTACATTGCATTGACTCTTGTGGAAGTATGAATTGATGTCAACATCTTTCTCTGGTCACTGTAGGATTGGCAGAACTTGCATCAAGAAAGTATAAACCGGCTGCCAAGTGCTTCCTGCAAGCCTCCTTTGACCACTGCGACTTTCCTGAGGTTGGTGCCATTTCTGACCCTGCTCTAATGCTGTGTCATATTGAATTGCATTATAAGTTGAAATGAAGATGAGTAGATGCAGTGCTTTCCTACAGTTTGTAATGATATTTTTTTTCTCTCTTTAGTTACTTTCTCCCAGTAATGTAGCTGTGTATGGGGGGCTCTGTGCCCTGGCTACGTTTGACAGACAGGAATTGCAGCGAAATGTCATCTCAAGCAGG[T/C]GAATTTAAATGTTTAGCATTTGCAGTCTCTTTATATATGAGGTATATTTTTGGTTGTGGATCAAACCTCACTGATTTGTAATTTACTCTTATTTTTGTTTCAGCTCCTTTAAATTATTTTTAGAGTTGGAACCTCAAGTCCGTGATATTATCTTCAAGTTTTACGAGTCAAAGTATGCATCTTGTCTGAAAATGCTGGATGAAATGAAGGTAAGATTGACTAAGCAGAGTTTCAGATAGTGATTTCTGTCTCTTGTGGTTGGAATATTGTGATTCTTGAGTGTTTACTCTCTGTATTTCAGGATAATCTCCTCCTAGACATGTATCTGGCCCCTCATGTAAGAACACTGTACACACAAATCAGGAACAGAGCCCTCATACAGGTACGTAAAAGGATAATTTGTGTTGATTTGTGATCTTGATTTACATGTTAACCTTGACTTATGGTTAATAGGATTTAGATTTTTGTTGAATTGAGAGTAAGAGGTTGTTTTTATTATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11784
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000059506 Essential Splice Site 345 487 10 14
ENSDART00000141106 Essential Splice Site 348 490 10 14

The following transcripts of ENSDARG00000040650 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 3 (position 36238272)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 36109556
GRCz11 3 36239154
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTAYGAGTCAAAGTATGCATCTTGTCTGAAAATGCTGGATGAAATGAAG[G/A]TAAGATTGACTAAGCAGAGTTTCAGATAGTRATTTCTGTCTCTTGTRGTT
Long Flanking Sequence:
TCAAGAAAGTATAAACCGGCTGCCAAGTGCTTCCTGCAAGCCTCCTTTGACCACTGCGACTTTCCTGAGGTTGGTGCCATTTCTGACCCTGCTCTAATGCTGTGTCATATTGAATTGCATTATAAGTTGAAATGAAGATGAGTAGATGCAGTGCTTTCCTACAGTTTGTAATGATATTTTTTTTCTCTCTTTAGTTACTTTCTCCCAGTAATGTAGCTGTGTATGGGGGGCTCTGTGCCCTGGCTACGTTTGACAGACAGGAATTGCAGCGAAATGTCATCTCAAGCAGGTGAATTTAAATGTTTAGCATTTGCAGTCTCTTTATATATGAGGTATATTTTTGGTTGTGGATCAAACCTCACTGATTTGTAATTTACTCTTATTTTTGTTTCAGCTCCTTTAAATTATTTTTAGAGTTGGAACCTCAAGTCCGTGATATTATCTTCAAGTTTTACGAGTCAAAGTATGCATCTTGTCTGAAAATGCTGGATGAAATGAAG[G/A]TAAGATTGACTAAGCAGAGTTTCAGATAGTGATTTCTGTCTCTTGTGGTTGGAATATTGTGATTCTTGAGTGTTTACTCTCTGTATTTCAGGATAATCTCCTCCTAGACATGTATCTGGCCCCTCATGTAAGAACACTGTACACACAAATCAGGAACAGAGCCCTCATACAGGTACGTAAAAGGATAATTTGTGTTGATTTGTGATCTTGATTTACATGTTAACCTTGACTTATGGTTAATAGGATTTAGATTTTTGTTGAATTGAGAGTAAGAGGTTGTTTTTATTATTGTTATTATTATTAACAATTACTGTATTTATAAAATTATTCAAACACAAAAAAGTAATGATATACAATGCAGTTTTATTTTTTATTTCTTTAGTGTTGTTCTAACTGTTGGTTATTAATTGTAAGATGATTTTGGTTAGTTTTAGTCTTTATGGTTGTTGTTTTGTGTCTTAATTTATTATATATCTATGGTTGTCTTTTTTTATTGGTCA
Associated Phenotype:
Not determined