Busch Lab

ZMP

ephx2

Ensembl ID:
ENSDARG00000040255
ZFIN ID:
ZDB-GENE-041212-70
Description:
epoxide hydrolase 2 [Source:RefSeq peptide;Acc:NP_001008642]
Human Orthologue:
EPHX2
Human Description:
epoxide hydrolase 2, cytoplasmic [Source:HGNC Symbol;Acc:3402]
Mouse Orthologue:
Ephx2
Mouse Description:
epoxide hydrolase 2, cytoplasmic Gene [Source:MGI Symbol;Acc:MGI:99500]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa36296 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa14928 Nonsense Available for shipment Available now
sa42857 Nonsense Mutation detected in F1 DNA Not yet available
sa6457 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa28783 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa36296
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000058890 Essential Splice Site None 557 1 20
Genomic Location (Zv9):
Chromosome 17 (position 5839879)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5918815
GRCz11 17 6076045
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGCTAAAGTCATAAGTGTAGCAGTGGTCTCTTCAAGCGACGCACAGCAG[G/A]TAAATAAACATACAATTTCGCCAAAATGAACTTTACTTTACTTTTCGACA
Long Flanking Sequence:
TAATTATTCATTTATTATGCATTGTTTTATGAACACGTTATTATACTGTATATGCATAGTATATATAGTAGCTTTATTTAATCAAATTGAGATTGATATTAAAAACTTTGTAGTCGCTAATTCCTATAATCTGACAAAGTTTGCGATTTATGTAACTATTGACTTTAGAGCTCTATCCACTACTAGTGAAAGGCTTTTCTTTTGAATATTAAATAGGTCCTGTTGACTTCCTCTAGCGTAATTCGTCTATTCTAATAAGCAGCGGAGGATTTGTGGATTCGTCCAATCACCATCTTTCCTCCGCCTGCCTTTCAGCCAATCAGGTACGAGTTTTCAGTGAACGTCAAGACGTGACATTAATATGTATGAGCTGTTTCCTTCGCCACACTAGAACTGGTGTTTGTAGTATTTGGGCTGGGTTTAAGAGCAGTATATTAGGAGTTTTCCTATGTGCTAAAGTCATAAGTGTAGCAGTGGTCTCTTCAAGCGACGCACAGCAG[G/A]TAAATAAACATACAATTTCGCCAAAATGAACTTTACTTTACTTTTCGACAGCGTTACGTAATGAACTTTGTCCTGCTTAACTGTGTAGTTTTGACCAACCAGAATGCCTGTCAAGCCTAAAGTATAATGTTTTCTGCTTTTGTATTTCTCTTTTTTTGCACAGTGTCAGTTTTTAAGGGATTTTCAACTAGTTTCCAATGAAGAAGGCAGTGTTGTTTAGTTTGTGGGGTGGTGTTGTTACCCCACAGATTGGTCAAGCATTTCAGAAGTTTGAGGAAACCACTGGCATTTCAAAGTATGTGTCTTACTTTCTTTTAAAACAGTATTTTATACCAATAAAAATAAATGAATGTGCTTTTTTATATTAGTTTTTTTACATCTTTTATTTAAGGAAGTCACTGACATTTGAAAGTATTAGATTTTTTTTCTTTTAGCAGTACATGACATTTTGTGTAAAAAAATAAGTAAATAAATGTGCATTATTAGTTTTTTCATCTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14928
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000058890 Nonsense 272 557 8 20
Genomic Location (Zv9):
Chromosome 17 (position 5828862)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5907798
GRCz11 17 6065028
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCTGTTCTCCTGTGTCATGGATTCCCTGAGAGCTGGTTTTCCWGGAGGTA[T/A]CAGGTGAGAAAYATMAAACTTTAYAGCTGATGTAACTGAAACGCAGACCT
Long Flanking Sequence:
AAGATGTTTTAATCTGTCCTATTTAGACATATGCAGATATTTAGTATATTGTGATAATGAAAATGAGGGTGACACGGTGGCTCAGTGGTTAGCACTGTGTCCTCGCTGCAAGGAGGCGACTGGTTTGAGTCCCGGCTGGGTCAGTAGGCATTTCTGTGTGGAGTTTGCATGTTCTCCCTGTGTAGGCGTTGGATTTCTCCGGGTGCGCCGATTTCCCCCGCAGTCCAAACACAGGCGCTATAGTGTATGAGTGTAAATGAGAGTGTTTCCCAGTACTGGGTTGCAGCTGGTAGGGCATCTGCTGCGTAAAAATAAGGGACTAAGCCGAAGGAAAATGAATGAATATAGAGGAAGGCTAATAATTCAGGAGGGCTAATAATTCTGACTTCAACTGTCTGTGTTTGTAAGCCTGGTGTGAAGATCCACTATGTGGAGATGGGAGACGGTCCACCTGTTCTCCTGTGTCATGGATTCCCTGAGAGCTGGTTTTCCTGGAGGTA[T/A]CAGGTGAGAAACATCAAACTTTATAGCTGATGTAACTGAAACGCAGACCTTTGAAGATGAAGAGATTAGACTAGAAGAGCCTGGCGGATTTAGGCTTAAAGATCAGTCTGGTAAGCCACAGGTTGGTGGGTTTGAAACACCAAAAGGGTGATTCATGAGATTTCAGTAGAATATCTTTGATTGCGACCCCAGAGGATGAGTAAACCTTACATTGCATAATAAAGCAGACCTGAAGCCAGCCTGGTGAACGAGGTGGTTCTTTTTGTCTCAAAAGCTGGACATTTTTAGTTATTTGGTTAATTTTCTATTTAATTAAAAATATATGTATATATAATTCATTTTTATTTTAAACTTTCTATTAATTGCTGTATTTAAGTGACATTTAAGCACCATTATTTTGCTGGATTAGCCTGTCAGATAGTTAAAAAATAGGAATCTGTTAAAGTTTTAATTTAAATCTGTTGCCTGTTGTCATTTATTAGACAAATGACAAACTGGAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42857
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000058890 Nonsense 342 557 12 20
Genomic Location (Zv9):
Chromosome 17 (position 5811159)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5890095
GRCz11 17 6047325
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCACTCTGGTGGGCCATGATTGGGGCGGCGTTCTGGTCTGGAACATGGCA[C/T]AGTTTCACCCTGAGAGAGTCCGGTATATTATACACTATTACAGCTGTTTA
Long Flanking Sequence:
GTCTACAGAACAAACCATCTTTATACAATAATTACCCTAACGTAGTTAACCTAATTAACCTAGTTTGGCCTTTAAATGTCACTTTAAGCTGTATAGAAGTGTATTATTTAATCAATCAAATATTATTTACTGTCATCATGACAAAGATAAAAGAAATCAGTTATTAGAAATGAGTTATTAAAACTACTATGTTTATAAATGTGGTGAGAAAATCTTTTCTCTGTTAAACAGAAATTGGGGGAAAAAAAGTAAACGGGGGCTTATAATTCTGACTTGAACTGTATATATACATGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATCCTCATGTCATGTTCTTTTGTTATTCAGCTGGTTGTGGTCATTTCTGAGCTTGTGTGTTTGTGTTCCGCAGGCCATTGCTCAGGTCACTCTGGTGGGCCATGATTGGGGCGGCGTTCTGGTCTGGAACATGGCA[C/T]AGTTTCACCCTGAGAGAGTCCGGTATATTATACACTATTACAGCTGTTTAACGTATTTATATTGACTGTGTCCGATTGTTATTGTGTTTAGTGTAAAAACTGGACAAAATACATCCACCATGCTTCTATTTATTTTGTCGTAAACAAATAAATACATGCATTCATAAATTGCTTGTTTGTTTAATTGTACTTTTTGTGTCAGAATATGTTTGCATTAAGAGAGGAAAATGATTTAAAATGAAAATCATATTGAAAATCAGATTTGAACACATTAAAAGCAAAAACAAATAAAGCAATCCTAAACGGTTTATATATTATTTGAAAACTTTTTTCTTTTGATTTTGTACTTAAATATAATTTCGTTTAAATTTTTGCTGAAATATGATTTTCGTTCTGACACTTCCTTATGATATTCTGCCAGTTTAAAGGTTTTTTTTTGTCTTCAGATATTTCATTCTTCTGTGGGAGATCATTTTCCATATTAAACTTGTGAAGTGTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6457
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000058890 Essential Splice Site 425 557 15 20
Genomic Location (Zv9):
Chromosome 17 (position 5802363)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5881299
GRCz11 17 6038529
KASP Assay ID:
554-5381.1 (used for ordering genotyping assays)
KASP Sequence:
TCTGCAGGATGGATTTCCTAAGTTATCCCCTGCTGGAGTTTGTCAGAGAG[G/A]TAAATACATCAAACNNNNNNATTTTCAGTTTTTGATTTGTCTGCATCTTT
Long Flanking Sequence:
AGTCGTGGGCCGCATTAAATTTGTTTAATATAAATATATTAAGGCGAGGCAGTGGCGTAGTAGGTAGTGCTGTCGCCTCACAGCAAGAAGGTTGCTGGGTCGCTGGTTCGCTGGTGTGGATGTTGCGGCTGGAATGGCATCCGCTGCGTAAAAACTTGCCGGATAAGTTGGCGGTTCATTCCGCTTTGGCGACCCCAGATTAATAAAGGGACTAAGCTGACAAGAAAATGAATGAATGAATGAATAAATATATTAAACTACAAATATAAAGAATGATAAACCTAAAACTAAACCGACTAAAATAAGCGAAAGAGAAAAGTGATACTGCTAAAGCTTAAACTACAAATAAAATGAAACAATACAAATACAAGGTATAAGATATTAAATCTAATACTATATTACAATATTGAGTATTGTTCAAATATATACTGAGAAACTTTATTTTTATAATCTGCAGGATGGATTTCCTAAGTTATCCCCTGCTGGAGTTTGTCAGAGAG[G/A]TAAATACATCAAACTATAACATTTTCAGTTTTTGATTTGTCTGCATCTTTTACTATTGCAGATGCGCACTTTGCAATATGGATATGTTTCACTGCTGTTCAGGTTGTGATTTGCTCAGCTCTGCTGTTTCTCAGGTGGATTGTTTGTTGGGTCTCCGGATGATCCTCCGCGCAGCTCCATGCTGAGTGTGTCTGCGCTTCAGTTTTACACAGAGCAGTACAGCAAGAGCGGATTCAGGTACACCGAGAACATGAGCTCCTCGATCTGTGTGCTTTTTGTACTTCTGTCTTCACGCTGCAGAATGTTTTTTGTTGTCTTGTCATCAAGTGACTACTATTTTCTTCCAGTAGTTAAGTAATGTGTACAATGTAAAATATTCACAATAGAATTAAAAGCTTCAAAATGTCCTGAAACAATTTAGTTTCTTGTGTGTAAATAGAATAATATGCGTAATATTTAATTTAATGTTAACTTTATTAAATTTTACGTAATTTATCAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa28783
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000058890 Nonsense 454 557 16 20
Genomic Location (Zv9):
Chromosome 17 (position 5802143)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 5881079
GRCz11 17 6038309
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGCAGCTCCATGCTGAGTGTGTCTGCGCTTCAGTTTTACACAGAGCAGTA[C/A]AGCAAGAGCGGATTCAGGTACACCGAGAACATGAGCTCCTCGATCTGTGT
Long Flanking Sequence:
CAAGAAAATGAATGAATGAATGAATAAATATATTAAACTACAAATATAAAGAATGATAAACCTAAAACTAAACCGACTAAAATAAGCGAAAGAGAAAAGTGATACTGCTAAAGCTTAAACTACAAATAAAATGAAACAATACAAATACAAGGTATAAGATATTAAATCTAATACTATATTACAATATTGAGTATTGTTCAAATATATACTGAGAAACTTTATTTTTATAATCTGCAGGATGGATTTCCTAAGTTATCCCCTGCTGGAGTTTGTCAGAGAGGTAAATACATCAAACTATAACATTTTCAGTTTTTGATTTGTCTGCATCTTTTACTATTGCAGATGCGCACTTTGCAATATGGATATGTTTCACTGCTGTTCAGGTTGTGATTTGCTCAGCTCTGCTGTTTCTCAGGTGGATTGTTTGTTGGGTCTCCGGATGATCCTCCGCGCAGCTCCATGCTGAGTGTGTCTGCGCTTCAGTTTTACACAGAGCAGTA[C/A]AGCAAGAGCGGATTCAGGTACACCGAGAACATGAGCTCCTCGATCTGTGTGCTTTTTGTACTTCTGTCTTCACGCTGCAGAATGTTTTTTGTTGTCTTGTCATCAAGTGACTACTATTTTCTTCCAGTAGTTAAGTAATGTGTACAATGTAAAATATTCACAATAGAATTAAAAGCTTCAAAATGTCCTGAAACAATTTAGTTTCTTGTGTGTAAATAGAATAATATGCGTAATATTTAATTTAATGTTAACTTTATTAAATTTTACGTAATTTATCAATGTATTACTTGTTAATTGAATTAACTATATGCGTATGAAAAGTGTGTATGTGTATACAGTAGGGATGTAACGGTATCAGAATTTCACGGTACGATAATACATCGGTATGAATGGGACGGTACAATATTTATTGAATAATTTACAGGAAAAACAAAACTAATGAAAAACTCGGAAAAAAAAGTGCCAAAAGTGTTTATTTACCTTAGCACTGAACATATCAA
Associated Phenotype:
Not determined