ZMP
nek4
Ensembl ID:
ZFIN ID:
Description:
serine/threonine-protein kinase Nek4 [Source:RefSeq peptide;Acc:NP_957306]
Human Orthologue:
NEK4
Human Description:
NIMA (never in mitosis gene a)-related kinase 4 [Source:HGNC Symbol;Acc:11399]
Mouse Orthologue:
Nek4
Mouse Description:
NIMA (never in mitosis gene a)-related expressed kinase 4 Gene [Source:MGI Symbol;Acc:MGI:1344404]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa21837 | Nonsense | Available for shipment | Available now |
| sa31813 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa21837
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000058728 | Nonsense | 277 | 849 | 6 | 16 |
Genomic Location (Zv9):
Chromosome 11 (position 4076631)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 3995135 |
| GRCz11 | 11 | 4014522 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACGCATTGATCTGTCCTGTTACTGATTCTGAACAGGAAAACCGCCAAGT[C/A]ACGGAAAAATGCAGCGAATGGCAAACTGAACAGTGCTGGATCAGATGCGT
Long Flanking Sequence:
CCTCTAACCATTGACTACCATAGCATTTGTTTTTTTTTACTATGGAAGTCAATGGTTACAGGTTTCTGACATTCTTCAAAATATCTTTTTTTGCATTCAACAGAAAAAAACATTGGGAATCACTTGACGGTGATTAAATAGTGAATACATTTTCACTTTTTGATTAATCTACAGTCCATTCATATCAGTACTCTCTCCATACCTCCTCGCATTATACTAACATCATTGATTATTTACTTTCAATATTCAGTTACCACAGATGCCAAGTAAGTACGACCCTCAGCTGGGAGAACTGATAAAGCGCATGCTGTGTAAGAAGCCAGAGGACAGACCAGATGTCAAACACATCCTCCGACAGCCATATATTAAACATCAGATCTCCATGTTCTTGGAGGCCACTAAAGAGTATGTCTGCCTATTTCTAGCCTTAAAATTATATTAAAATCTAAGCACGCATTGATCTGTCCTGTTACTGATTCTGAACAGGAAAACCGCCAAGT[C/A]ACGGAAAAATGCAGCGAATGGCAAACTGAACAGTGCTGGATCAGATGCGTCTACCAAACCAAATCAGGTAGTTCAGCCACAGTGTCTCAACTCTGAGTCAAAGACCTGCGGAAAAAAGGTTAGAGGAATGCCATCTTGGAAATCTTATGCACGTGTGTTTTAAATCGACATGATTTTAGTTAGGGCTGCATGATCTCAATGATTTTGCTTAACATTTGTACACTGCTAAAAATGCTTTTCTTGTTTAGATTTTTTGTCTTGTTTCTAGTCTAAATATCTCAAATTTCTTATATCAAGAAGAATTTTCTTGAAAAGCAAAGAAAATTTTTGAGAAATAATATACCAATATTAAGTGAATTTTTCCTTAAAACAAGCTAAATATTCTGCCAATGGGGGTAAGCAAAATAATCTTGTTTTTTCTTTTGACGTAAGATTATTTTGCTTACCCCATTGGCAGAATATTTTGCTTGTTTTAAGAAAAAACACTTAATATTGGCATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa31813
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000058728 | Essential Splice Site | 316 | 849 | 6 | 16 |
Genomic Location (Zv9):
Chromosome 11 (position 4076511)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 3995015 |
| GRCz11 | 11 | 4014402 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTTCAGCCACAGTGTCTCAACTCTGAGTCAAAGACCTGCGGAAAAAAGG[T/C]TAGAGGAATGCCATCTTGGAAATCTTATGCACGTGTGTTTTAAATCGACA
Long Flanking Sequence:
CACTTGACGGTGATTAAATAGTGAATACATTTTCACTTTTTGATTAATCTACAGTCCATTCATATCAGTACTCTCTCCATACCTCCTCGCATTATACTAACATCATTGATTATTTACTTTCAATATTCAGTTACCACAGATGCCAAGTAAGTACGACCCTCAGCTGGGAGAACTGATAAAGCGCATGCTGTGTAAGAAGCCAGAGGACAGACCAGATGTCAAACACATCCTCCGACAGCCATATATTAAACATCAGATCTCCATGTTCTTGGAGGCCACTAAAGAGTATGTCTGCCTATTTCTAGCCTTAAAATTATATTAAAATCTAAGCACGCATTGATCTGTCCTGTTACTGATTCTGAACAGGAAAACCGCCAAGTCACGGAAAAATGCAGCGAATGGCAAACTGAACAGTGCTGGATCAGATGCGTCTACCAAACCAAATCAGGTAGTTCAGCCACAGTGTCTCAACTCTGAGTCAAAGACCTGCGGAAAAAAGG[T/C]TAGAGGAATGCCATCTTGGAAATCTTATGCACGTGTGTTTTAAATCGACATGATTTTAGTTAGGGCTGCATGATCTCAATGATTTTGCTTAACATTTGTACACTGCTAAAAATGCTTTTCTTGTTTAGATTTTTTGTCTTGTTTCTAGTCTAAATATCTCAAATTTCTTATATCAAGAAGAATTTTCTTGAAAAGCAAAGAAAATTTTTGAGAAATAATATACCAATATTAAGTGAATTTTTCCTTAAAACAAGCTAAATATTCTGCCAATGGGGGTAAGCAAAATAATCTTGTTTTTTCTTTTGACGTAAGATTATTTTGCTTACCCCATTGGCAGAATATTTTGCTTGTTTTAAGAAAAAACACTTAATATTGGCATATTATTTCTTAAAACAAGGCAATATGTTGTGCTTGTGTAGAAAATTCTTCTTGATTTAGGAATTTTTAGATATTTGGACTAGAAACAAGGCAAAAAAATCTAAGTAAGAAAAGCATTTTTT
Associated Phenotype:
Not determined