ZMP
mcm4
Ensembl ID:
Description:
DNA replication licensing factor MCM4 [Source:RefSeq peptide;Acc:NP_944595]
Human Orthologue:
MCM4
Human Description:
minichromosome maintenance complex component 4 [Source:HGNC Symbol;Acc:6947]
Mouse Orthologue:
Mcm4
Mouse Description:
minichromosome maintenance deficient 4 homolog (S. cerevisiae) Gene [Source:MGI Symbol;Acc:MGI:10319
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa37936 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa1949 | Nonsense | Available for shipment | Available now |
| sa12196 | Nonsense | Available for shipment | Available now |
| sa18098 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa37936
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000058562 | Nonsense | 108 | 750 | 4 | 18 |
| ENSDART00000058564 | Nonsense | 108 | 845 | 4 | 17 |
| ENSDART00000128767 | Nonsense | 108 | 845 | 4 | 17 |
Genomic Location (Zv9):
Chromosome 24 (position 37053223)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 35670485 |
| GRCz11 | 24 | 35558582 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGACACCGGCGCGCCAGCGGGCTGACCTGGGATCTGTGCGGAAAGCCCCG[C/T]AGGTCGACATGCACTCTGAGCCGGTGAGGGACTCTTGATAATTACAGTTT
Long Flanking Sequence:
AAGAGAGACCCTCCGACCCGTGAGTCTCGTTCTCTGTCCGTCCGTCTCTGCACAGATCTGCTGTTTTCTGCTCAGGCTTGTGTTTGATGGTTTGTGTGTGTGTGTGTGTGTGTGTTCACAGCGGCGAGCGAGGATCCTCTGTCTCCTCCATCCCAGCGCTCCAGAGCTCATGATACCTCCACTGAGCTGCAGCCAATGCCCACCTCTCCGGCTCAGGATGCATCGCTGTTCTCCAGCCCCATGGCCCCGCGCTCCGGTACTGCTCAAAAATACTGCTCGCAGTATTAAGATCGGTGCATCACTAAAATGAAGCAGGTGATTTGGGTGAAGGTTTGTGAACATCAGGATTTGTTGATCTAGTCTTGCAGAGTGAGATTGATGCCAGTTCTCCTCTGATGTACGGGACGCCCAGCTCCAGGGTGGAAGGAACGCCCCGCAGCGGCATCCGCGGGACACCGGCGCGCCAGCGGGCTGACCTGGGATCTGTGCGGAAAGCCCCG[C/T]AGGTCGACATGCACTCTGAGCCGGTGAGGGACTCTTGATAATTACAGTTTCACTGAACCCTTGTGTACTGTTCAAATCGACAACCCTTTCGTTATGTTTGGGGCTGTTTTTGCCCCATTGACTTCCACTATTATTACTTTTTTGATAGCAAAGCTATGACAGTATATAGTCATGCATTCTTGGTTATTGGTGGTTTTCCCTGTTAGGAAGAGGTACAGTTTGTGATTTTTTTTTTACTGTTGATCATCCGTTGGTAGCATTAACCCTTTAAATCACGGGTCAGGAACCTTTTTTCAGCACAGAGCCATTTCAGAATTTTTTTTAATTAAATGCATTTTTTAAAGGAGCCATATGGGGCGTGTGTTTAACAAAACCTTTATTTATAAACAAAACCTTTATTTCCATGCACAACTCAAAAATAAACAAATATGACACATCACAATGAATGAAGTAGGGATGCAACAATCTAGTTAGCCCACAATTCATTACATACCTCAGTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1949
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000058562 | Nonsense | 387 | 750 | 11 | 18 |
| ENSDART00000058564 | Nonsense | 387 | 845 | 11 | 17 |
| ENSDART00000128767 | Nonsense | 387 | 845 | 11 | 17 |
Genomic Location (Zv9):
Chromosome 24 (position 37041363)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 35658625 |
| GRCz11 | 24 | 35546722 |
KASP Assay ID:
554-1937.1 (used for ordering genotyping assays)
KASP Sequence:
TATYGTGCTCAGGCATCTACAGAGCTGCCCCGATGCGTCTGAACCCACGG[C/T]AGAGCCAGGTGAAGTCTGTWTACAAGACCCACATTGACGCCATTCACTTC
Long Flanking Sequence:
TTTCTGTCATTAAACTGCGGAGAAGCACCACATTGTCGCAAGTTTAATGATGTACAGAACGGAATGCCTCAATAAATCCGATCTGCCTGTTTACATGACAGTCGCATTGTCACATATCCGATCTAAATCTGATTTATTTCCCAATGCGAAGGAGGCCTGAAACCGATCTCTGAACATCCGAATGCATGCCTTTTTTTTTTTTTTTGTGTTTACTCAGTCGTAGAACAGATCCGATCTGCGTCACATATGAGCAAAAAATCGGAATTGGGTCACATTTAACTGGCAGTGTAAACGGGGGCTTAGGTTACAAAATGAAAACACTGACTGAATCCTTTATAAGAACCGGCATAGGCTGTTTTTTTTTTTTTTTTTTTGGTACATTTTTTTTGTATTTTTTTACACTCATGTTTTTGTCTTTCGTTTGGCAAAATGACTGAGCAACTCTTCTTTTATTGTGCTCAGGCATCTACAGAGCTGCCCCGATGCGTCTGAACCCACGG[C/T]AGAGCCAGGTGAAGTCTGTTTACAAGACCCACATTGACGCCATTCACTTCCGCAAGACTGACGAGAAGCGTCTGCATGGACTGGACGAGGACGGAGAGCAGAAACTCTTCACTAAAGAACGAGTCGCTCTGCTAAAAGAGCTAGCCGCTAAACCTGACGTCTATGAGCGCCTGTCCTCTGCTCTGGCTCCCAGCATCTACGAACACGAGGACATCAAGAAGGTCAGTATGATGGGAAACTCTAAATTGATGAAGTTGTTTTGAGTGTAATTGAATTGCTCCTCCACTTGCGAACTTGTCCCACTCCGTCTTCATGTGTTGATTGAGATTACGTCAGTCATCGAATAAAAATGCACATTTTAAAGCACTTCACGAGACCTTTACATCAAGGAATATGCTGTCAGGACACAAGTTGATGGTGTTGATGTTTTCCAGGGCATCCTGTTGCAGTTATTTGGCGGGACGCGTAAGGACTTCACTCAGACGGGCCGAGGAAACTTC
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |
Mutation Details
Allele Name:
sa12196
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000058562 | Nonsense | 661 | 750 | 14 | 18 |
| ENSDART00000058564 | Nonsense | 661 | 845 | 14 | 17 |
| ENSDART00000128767 | Nonsense | 661 | 845 | 14 | 17 |
Genomic Location (Zv9):
Chromosome 24 (position 37038377)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 35655639 |
| GRCz11 | 24 | 35543736 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGCGCACCACCTTGTCTCTCTGTATTATCAGAGTGAAGAGCAGATTGAA[G/T]AGGAGCATCTGGACATGGCTGTACTGAAAGACTACATCGCCTTCGCTCGC
Long Flanking Sequence:
TTTGTAATGCAAAGTGTTGTGCTGCTTAATATTATTTGGGAACCAACTTCCTAAGTGCAGTGTTTATGTGAAATGCCAATAATTATGTGATAATTTTAATGTTTAAAAGTAAAGAAAAAAAACATTTGGATGATATAATTAAATATTAGTTTTGTCAGTATAGAAGTGTTTAATTTAAATTAGTTGTCAAATTAAATTATAAACTAACTTTAAAGACATTTATTAACAAATAGGGCAAATTTACATAAAAGAACTTAATTTTTTTTTTACTTTTGTGATCTCAAAGATTATTAATTATTCATAATATTAGTTCAACATAAGCTGCTTTTTATTTTAATGTTTTTTTTTCTTCTTTTGTCTAATAATTGTCTCTCTGCATCTGTTTTTTTTCCAGGTTTGATTTGATCTTCCTAATGCTGGACCCTCAGGACGAGGCGTATGACAGGCGTCTGGCGCACCACCTTGTCTCTCTGTATTATCAGAGTGAAGAGCAGATTGAA[G/T]AGGAGCATCTGGACATGGCTGTACTGAAAGACTACATCGCCTTCGCTCGCACAACTGTACATCCCAGACTGAGTGAAGAAGCCAGTCAGGCCCTTATTGAGGTATAGAAACACTATAACAGCACAGCATTATATGTTGCCAGCTTTGTTACTTTTAATTTAAGGACGATACTGATATTTCACTGTGATTAGCTGATCTTGATTTATTTTTTAATTGGCCATTTCATATGTCAGATTTCTTTTGCAATCAAATTGTTCGTTGTCTCTTTTATAATTAAAGGGGCTGTATGTAAGTTTTGGACTATTAATACTATAATATCCATAATATTTTTGCAGATATTTCAGAAATATGCGAAGTCAGGGCTCGAAATTGCGACTGTTTTGGTCGCAAATGCGCCCGAGAATAATCTATGCAACCTCATAATATATATGGGAGCATTAGTGCGACTGCAGATAATGGTTGTAGTGTGACCTGTTTAGATTTTTTCTAAAAACGTGCTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa18098
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000058562 | Nonsense | 696 | 750 | 15 | 18 |
| ENSDART00000058564 | Nonsense | 696 | 845 | 15 | 17 |
| ENSDART00000128767 | Nonsense | 696 | 845 | 15 | 17 |
Genomic Location (Zv9):
Chromosome 24 (position 37035841)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 24 | 35653103 |
| GRCz11 | 24 | 35541200 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTTTAAYAGATCCAATGTCAAATGTGTAATTTTGCTCCTCACAGGCCTA[T/A]GTGGACATGCGCAAGATCGGCAGCGGTCGAGGGATGGTGTCTGCGTATCC
Long Flanking Sequence:
AGTTGAATTATTTGAAGTTGCATAAATATTTTGTTGTTTGTTTTAATCCGTTTTAATCTTGCCATGAAATAGCCAAACATTGCTGATGTGGCAATAAAATAAATAAAAAAAAGACAGGCAAAAACAAGTAAAATATTTGCGCTGCACTGTAGAAATGCTCCTTTTCGATCGCGTTTGCATTGACTTCATATGTAATGTCAATCTACTTGTGTGAATACTTTGACTTTTGGCTCACTCCTGCTGGTCTCAGCAACCTGAGGAGGGGCTGGGTGGGAAAAAAAATCCAATATTTTGAATTTGGACTGCAATACCTAGTTCATCCACTAGATGTCACATACTGCACTTTTAAATAATGATCCTAACAAAGAAATGCTGCGCACATTTAGCATGGGCAGTTCAAATCAATTAGACCTAATATACATGATTATCATGGGACATTTGGCAACCCTAGTTTTAACAGATCCAATGTCAAATGTGTAATTTTGCTCCTCACAGGCCTA[T/A]GTGGACATGCGCAAGATCGGCAGCGGTCGAGGGATGGTGTCTGCGTATCCCCGTCAGCTGGAGTCACTCATCAGGCTAGCTGAAGCTCATGCTAAAGTACGCTTCTCTGGAAAAGTGGAGACCATCGATGTGGAGGAAGCCAAGAGACTCCATCGAGAAGCCCTGAAACAGTCCGCAACTGATCCCAGGACAGGATTTGTGGATATTTCCATCCTCACCACAGGTAGGATTTACAGAATCACTGCAAAGATGCACTGTCATTGCTGGTTGGGTTGAGTCACTTCAATAGTGCAAGATGAACTAGTATGACTTATAAAAATATACAATAATAAAAAAAAAGATTAAATATTGAATTATTATTGTTTTGTAAAATTAATGTTGTTCAAAATATTAATATTTTTGAATGTCACTAATATGAGTCACTCGCTGAAAAGGTAAATGTTACAATAATAAAGTAATTAATTATTAACTCAAAGTTACTTAAAATATTACTATTAATT
Associated Phenotype:
Not determined