Busch Lab

ZMP

ctsl1b

Ensembl ID:
ENSDARG00000039173
ZFIN ID:
ZDB-GENE-980526-285
Description:
cathepsin L, 1 b [Source:RefSeq peptide;Acc:NP_571273]
Human Orthologues:
CTSL1, CTSL2
Human Descriptions:
cathepsin L1 [Source:HGNC Symbol;Acc:2537]
cathepsin L2 [Source:HGNC Symbol;Acc:2538]
Mouse Orthologues:
4930486L24Rik, BC051665, Cts3, Cts6, Cts7, Cts8, Ctsj, Ctsl, Ctsll3, Ctsm, Ctsq, Ctsr
Mouse Descriptions:
RIKEN cDNA 4930486L24 gene Gene [Source:MGI Symbol;Acc:MGI:1922258]
cDNA sequence BC051665 Gene [Source:MGI Symbol;Acc:MGI:2682300]
cathepsin 3 Gene [Source:MGI Symbol;Acc:MGI:2151929]
cathepsin 6 Gene [Source:MGI Symbol;Acc:MGI:1889619]
cathepsin 7 Gene [Source:MGI Symbol;Acc:MGI:1860262]
cathepsin 8 Gene [Source:MGI Symbol;Acc:MGI:1860275]
cathepsin J Gene [Source:MGI Symbol;Acc:MGI:1349426]
cathepsin L Gene [Source:MGI Symbol;Acc:MGI:88564]
cathepsin L-like 3 Gene [Source:MGI Symbol;Acc:MGI:1917452]
cathepsin M Gene [Source:MGI Symbol;Acc:MGI:1927229]
cathepsin Q Gene [Source:MGI Symbol;Acc:MGI:2137385]
cathepsin R Gene [Source:MGI Symbol;Acc:MGI:1861723]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa44754 Nonsense Mutation detected in F1 DNA Not yet available
sa22068 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa44754
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057237 Nonsense 137 336 5 8
ENSDART00000145570 Nonsense 153 352 5 8
Genomic Location (Zv9):
Chromosome 12 (position 17685359)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 16496533
GRCz11 12 16618407
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTTACTGTTTGGTGACTTTTTTTCTGTTTTGTGGTTTTAGAAACAATGT[G/T]GATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTC
Long Flanking Sequence:
AACATCCTAGATTAGAGATTTAAGCCCTGTGTGCTTTAATGGATTTTCTGCAAAATTACTTTAATTCTCAATATGAGGTGCTATCGATACCTTTAAAAGTACTATTTGTAAGACTTTTATTAACATTTCACTACAATCTATTTACTAGACAAATGAGGAGTTCAGACAGGCAATGAATGGTTATACGCATGACCCCAACCAGACGTCACAGGGCCCGTTGTTCATGGAACCGAGCTTTTTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGGTGAGTTTAAAGTAACTGAAAACTGCAAATGTTTTTTGCTAAATTAGGACCTATAGTTGCATCTATTACAATTGATCTATTTACAGTTGATCTGGTGAACCCAGTTTAATGTATAAATGGCTATTAAATGTCAGTATGTGTATCTGTAGCTTTACTGTTTGGTGACTTTTTTTCTGTTTTGTGGTTTTAGAAACAATGT[G/T]GATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAATGGAGGCCTCATGGACCAGGCCTTCCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGTAAGAATCATATTGTGACAGTTTCTGAGCAATGAATTTTTTTTTTTTGAAGACATGGGATTAAACTGCTGTATTTGCAGATTGTGGAAAAATGTCAAGTTTTGTTCAAAAGATTGTTCAAAAATTTTAGTTTTTTAATCTCTTTGAATGAAGATCATTAAGTATTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGCAGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATTCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22068
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000057237 Essential Splice Site 209 336 6 8
ENSDART00000145570 Essential Splice Site 225 352 6 8
Genomic Location (Zv9):
Chromosome 12 (position 17684929)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 16496103
GRCz11 12 16617977
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGC[A/T]GGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCA
Long Flanking Sequence:
GTCAGTATGTGTATCTGTAGCTTTACTGTTTGGTGACTTTTTTTCTGTTTTGTGGTTTTAGAAACAATGTGGATCTTGCTGGTCTTTCAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCTGATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAATGGAGGCCTCATGGACCAGGCCTTCCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATCTTGCAAGGGTAAGAATCATATTGTGACAGTTTCTGAGCAATGAATTTTTTTTTTTTGAAGACATGGGATTAAACTGCTGTATTTGCAGATTGTGGAAAAATGTCAAGTTTTGTTCAAAAGATTGTTCAAAAATTTTAGTTTTTTAATCTCTTTGAATGAAGATCATTAAGTATTTTAAGACTTCAATGTACCACTTTTTTCTTATTTTAACTTTGTGCTTGC[A/T]GGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTCGCTAAAATCACCGGATTCGTGGACATTCCCAGCGGTAATGAGCTTGCCCTAATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATTGACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGTAAGTGCCTGATATCCCTCAACTCTAGTTTTAATTCAATATTTGCAAAAATGGTTAGTTATACAATTATTACAAACTTATTACTGAACTTACTCTGCCTTAGCTCCTTTCTAATATTCTGATCTTTAGGCATCTATTATGAGAGAGCATGTAGCAGTAGTCGACTTGATCATGCAGTCTTGGTGGTTGGCTATGGTTATCAGGGTGCTGATGTTGCTGGGAATAGATACTGGATTGTGAAGAACAGGTATGATGCAAACAATCTTTAGTTTTGCGGGCACAAGCTTGATTGCATGTTTTCATATTTTATTATTTCTTTCAACTTTTTTT
Associated Phenotype:
Not determined