ZMP
DPYSL2 (1 of 2)
Ensembl ID:
Description:
dihydropyrimidinase-like 2 [Source:HGNC Symbol;Acc:3014]
Human Orthologue:
DPYSL2
Human Description:
dihydropyrimidinase-like 2 [Source:HGNC Symbol;Acc:3014]
Mouse Orthologue:
Dpysl2
Mouse Description:
dihydropyrimidinase-like 2 Gene [Source:MGI Symbol;Acc:MGI:1349763]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa7118 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa2444 | Essential Splice Site | F2 line generated | Not yet available |
| sa34289 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa5769 | Essential Splice Site | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa7118
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000056885 | Nonsense | 168 | 573 | 5 | 14 |
Genomic Location (Zv9):
Chromosome 8 (position 5362588)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5296750 |
| GRCz11 | 8 | 5145487 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTCTCTNTTTTTTTTTTTTTTTACAGGYGTCAACTYTTTTCTGGTCTA[T/A]CTGGCGTACAAAGACATCTTCCAGCTCAATGATTCCCAGGTAAACAACAG
Long Flanking Sequence:
GAATCTGTAATTCTGATTGTTTGCTAAGTTTATCCAAATGGATTCCTATGTGAAAAGTAAAATTAAGTATAAAGTTTTTACATTAAAAAGTAAAACAAATTTTAAAAAAAATGTTGTTGCCTAAAACCTTTTTCAAAGTTTTTTCAAACTTTTTCAAAGTTTTTGGGCAAAAAAAAAGACATTAGAGAGTAAATAAGATAAATAAAAATTATATAAAAAATCATAAAACGTGCTTGATAAGTTGGCGGTTCATTCCGCTGGGGCGACCCCGGATTAATAAAGGGACTAAGCCGACAAGAAAATGAATGAATTAATTAATAATTTAGAATTTGAACAGAATCTATCGTTTTAATTATTCATTGTTATTTCTTTATTTCTTTATTTCAAAATGAGTCCAGTTTTATTTATTTCCACACAAAAAAATAAGGATTTAGGCTAAAATTACACTTATTTTCTCTCTTTTTTTTTTTTTTTACAGGCGTCAACTCTTTTCTGGTCTA[T/A]CTGGCGTACAAAGACATCTTCCAGCTCAATGATTCCCAGGTAAACAACAGTAAAACACTCTATATAATGCATACAGTCAAGCCAAAAATGATTCAGACACCAGATATGATTTTTTGATTGTTTACTAGTGGGCCCAGGACACTACTTTATAATAATTAGCCCTCCTGAATTATTTGCCGCCCTGTATATATTTCACATTTCTAAACATAATAGTTTTAATAACTCATCTTTAATAACTGATTTATTTAATCTTTGCCATGATGACAGTAAATAATATTAGACTAGATATTTTTCAAGACACTTCTATACAGCTTAAAGCAGGCATGTCCAAACTCAGTCCTGGAGGGCCGGTGTCCTGCAAAGTTTAGTTCCAACCCCAATCAGACACACCTGGGTTTGCTAATCAAGCTCTTACTAGGCTTTCTTGAAACATCCCTGCAGGTGTGTTGAGGCAAGTTGGAGTTAAAATCTGCAGGACTCCGGCCCTTCAGGACCGAGTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa2444
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
Genomic Location (Zv9):
Chromosome 8 (position 5342554)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5315983 |
| GRCz11 | 8 | 5126254 |
KASP Assay ID:
554-3062.1 (used for ordering genotyping assays)
KASP Sequence:
GCAAACCCTTCCCAGACTACGTCTACAAGAGGATAAAGGCCCGCAGCAGG[G/A]TACATGCATGCACTCACACACACATCCAGACATTGTGGTTTTAAAAAGCA
Long Flanking Sequence:
TGTTGTATAAAAAATAGTTCATTCATTTTCTTTTCGGCCTAGTCCCTTTATTAATCAGGGGTCGCCAAAGTGTAATGAACCGACAACTTATTCAGCATATGTTTTACACAGCGGATGCCCTGCCAGTCCAGTATAATTCCAGTATAGTTCCAATATAATATAATATAATATAATATAATATAATACATAATGTTTTAGGATTATTTAATATTTAGTGACCTACTACTACTGTATGTGCTGTGGGTTGTGCTGAAATACATAATATTTTAATGATTTGTTTAAAGATCTGAGAGGTTTTCCCTGATTAATGCGTCTCTCAGGCGGTGGAGTATAACATCTTCGAGGGTATGGAGGTGCGTGGAGCTCCTCTAGTGGTCATCAGTCAAGGGAAGGTTGTTCTCGAAGAGGGAAACCTGCACACTACTGAGGGCTCTGGACGCTACATCAGCCGCAAACCCTTCCCAGACTACGTCTACAAGAGGATAAAGGCCCGCAGCAGG[G/A]TACATGCATGCACTCACACACACATCCAGACATTGTGGTTTTAAAAAGCAATGCACCATTCTTCACTTTTGTTGATGGCCAATCACGATACCCTAAAATGATTTATTTGATATACTACATTTTTTTAAAGGTAAGTGGTTGCAAACTATTATATGGGCTCAATTTAAACAAACAGATTAAGTTGAACATTACTAAATTCAGTTTGTTGGTAAGGTTCCAGACACAGTGGTTATAAATAGTAATGCACCATTCATCATTTTTATTATGGCCAATCATGAAACTGTAATAAGTCGGGTACAAGAATAGTCAGAAACAGAATTGTCAGACAGGCAAAGGTTAAAACAGGAACAGACAGGAGCATGAAGATAATCCAAAGTTTATCATGGCTGGAAAACACTAGCTGTGCATATAACCCACTGACACTGAATATTGAGTAGAGTGTAGTGGTGTAACGAATCACAAATCTCAAAATTCAGATCTCATTATGTTTTTTTAAATCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34289
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
Genomic Location (Zv9):
Chromosome 8 (position 5342554)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5315983 |
| GRCz11 | 8 | 5126254 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAAACCCTTCCCAGACTACGTCTACAAGAGGATAAAGGCCCGCAGCAGG[G/T]TACATGCATGCACTCACACACACATCCAGACATTGTGGTTTTAAAAAGCA
Long Flanking Sequence:
TGTTGTATAAAAAATAGTTCATTCATTTTCTTTTCGGCCTAGTCCCTTTATTAATCAGGGGTCGCCAAAGTGTAATGAACCGACAACTTATTCAGCATATGTTTTACACAGCGGATGCCCTGCCAGTCCAGTATAATTCCAGTATAGTTCCAATATAATATAATATAATATAATATAATATAATACATAATGTTTTAGGATTATTTAATATTTAGTGACCTACTACTACTGTATGTGCTGTGGGTTGTGCTGAAATACATAATATTTTAATGATTTGTTTAAAGATCTGAGAGGTTTTCCCTGATTAATGCGTCTCTCAGGCGGTGGAGTATAACATCTTCGAGGGTATGGAGGTGCGTGGAGCTCCTCTAGTGGTCATCAGTCAAGGGAAGGTTGTTCTCGAAGAGGGAAACCTGCACACTACTGAGGGCTCTGGACGCTACATCAGCCGCAAACCCTTCCCAGACTACGTCTACAAGAGGATAAAGGCCCGCAGCAGG[G/T]TACATGCATGCACTCACACACACATCCAGACATTGTGGTTTTAAAAAGCAATGCACCATTCTTCACTTTTGTTGATGGCCAATCACGATACCCTAAAATGATTTATTTGATATACTACATTTTTTTAAAGGTAAGTGGTTGCAAACTATTATATGGGCTCAATTTAAACAAACAGATTAAGTTGAACATTACTAAATTCAGTTTGTTGGTAAGGTTCCAGACACAGTGGTTATAAATAGTAATGCACCATTCATCATTTTTATTATGGCCAATCATGAAACTGTAATAAGTCGGGTACAAGAATAGTCAGAAACAGAATTGTCAGACAGGCAAAGGTTAAAACAGGAACAGACAGGAGCATGAAGATAATCCAAAGTTTATCATGGCTGGAAAACACTAGCTGTGCATATAACCCACTGACACTGAATATTGAGTAGAGTGTAGTGGTGTAACGAATCACAAATCTCAAAATTCAGATCTCATTATGTTTTTTTAAATCA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa5769
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
| ENSDART00000056885 | Essential Splice Site | 488 | 573 | 12 | 14 |
Genomic Location (Zv9):
Chromosome 8 (position 5342554)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 5315983 |
| GRCz11 | 8 | 5126254 |
KASP Assay ID:
554-3062.1 (used for ordering genotyping assays)
KASP Sequence:
GCAAACCCTTCCCAGACTACGTCTACAAGAGGATAAAGGCCCGCAGCAGG[G/A]TACATGCATGCACTCACACACACATCCAGACATTGTGGTTTTAAAAAGCA
Long Flanking Sequence:
TGTTGTATAAAAAATAGTTCATTCATTTTCTTTTCGGCCTAGTCCCTTTATTAATCAGGGGTCGCCAAAGTGTAATGAACCGACAACTTATTCAGCATATGTTTTACACAGCGGATGCCCTGCCAGTCCAGTATAATTCCAGTATAGTTCCAATATAATATAATATAATATAATATAATATAATACATAATGTTTTAGGATTATTTAATATTTAGTGACCTACTACTACTGTATGTGCTGTGGGTTGTGCTGAAATACATAATATTTTAATGATTTGTTTAAAGATCTGAGAGGTTTTCCCTGATTAATGCGTCTCTCAGGCGGTGGAGTATAACATCTTCGAGGGTATGGAGGTGCGTGGAGCTCCTCTAGTGGTCATCAGTCAAGGGAAGGTTGTTCTCGAAGAGGGAAACCTGCACACTACTGAGGGCTCTGGACGCTACATCAGCCGCAAACCCTTCCCAGACTACGTCTACAAGAGGATAAAGGCCCGCAGCAGG[G/A]TACATGCATGCACTCACACACACATCCAGACATTGTGGTTTTAAAAAGCAATGCACCATTCTTCACTTTTGTTGATGGCCAATCACGATACCCTAAAATGATTTATTTGATATACTACATTTTTTTAAAGGTAAGTGGTTGCAAACTATTATATGGGCTCAATTTAAACAAACAGATTAAGTTGAACATTACTAAATTCAGTTTGTTGGTAAGGTTCCAGACACAGTGGTTATAAATAGTAATGCACCATTCATCATTTTTATTATGGCCAATCATGAAACTGTAATAAGTCGGGTACAAGAATAGTCAGAAACAGAATTGTCAGACAGGCAAAGGTTAAAACAGGAACAGACAGGAGCATGAAGATAATCCAAAGTTTATCATGGCTGGAAAACACTAGCTGTGCATATAACCCACTGACACTGAATATTGAGTAGAGTGTAGTGGTGTAACGAATCACAAATCTCAAAATTCAGATCTCATTATGTTTTTTTAAATCA
Associated Phenotype:
Not determined