Busch Lab

ZMP

shhb

Ensembl ID:
ENSDARG00000038867
ZFIN ID:
ZDB-GENE-980526-41
Description:
Tiggy-winkle hedgehog proteinTiggy-winkle hedgehog protein N-productTiggy-winkle hedgehog protein C-
Human Orthologue:
SHH
Human Description:
sonic hedgehog [Source:HGNC Symbol;Acc:10848]
Mouse Orthologue:
Shh
Mouse Description:
sonic hedgehog Gene [Source:MGI Symbol;Acc:MGI:98297]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa8431 Nonsense Mutation detected in F1 DNA Not yet available
sa2069 Nonsense F2 line generated Not yet available
sa5719 Nonsense F2 line generated Not yet available
sa25111 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa8431
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056747 Nonsense 77 416 1 3
Genomic Location (Zv9):
Chromosome 2 (position 29769823)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 30071458
GRCz11 2 30054991
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGCCAGCGGCAAWTACGAAGGCAAAATCACAAGGAATTCAGAGAGATTT[A/T]AAGAGCTGATTCCGAATTATAATCCCGATATCATCTTTAAGGACGAGGAA
Long Flanking Sequence:
CTCCCCCTGCCATAGATTTGCTCTGTAATTCATATGGGTAGACTGCCTCTACTCATAAGCGTCTGACCCTACCTCCCGTCAAACTAAGTCGCTCTTTCGTCTCCCACTTAGCTGTGACAGCCAACCTCCAATGTGCTCATTCAGTGGCTATCGAGAGCGGTCGTTATTGCACCTGCTTCGGTAGTGGTCGTTGGGCAGCATCCATCCGGTTCGCGCGAGAAGACCCTGAGAGTGACTAAACTTTAAAGACCAGAAGAGATAATTCAAACGTCATGGACGTAAGGCTGCATCTGAAGCAATTTGCTTTACTGTGTTTTATCAGCTTGCTTCTGACGCCTTGTGGATTAGCCTGTGGTCCTGGTAGAGGTTATGGAAAACGAAGACACCCAAAGAAATTAACCCCGTTGGCTTACAAGCAATTCATCCCCAACGTTGCCGAGAAAACGCTTGGAGCCAGCGGCAAATACGAAGGCAAAATCACAAGGAATTCAGAGAGATTT[A/T]AAGAGCTGATTCCGAATTATAATCCCGATATCATCTTTAAGGACGAGGAAAACACAAACGCTGACAGGCTGATGACCAAGGTATGGACCAGGCGTGCGCAATTGCCCAAACGCACACACTTAGAATAGTGGATCTCCTTTTAGCTTTTAGCTCTGGGCTATATGAATGGCTATTGAGATTATTCAAATACTGATTGAGCATTACAGGAGCTGTAGATTAATATGCTGTGTTCTTTAACTTTGCAGTGCAAAGCATACATGTTTTATTACATAACTAGCAAATAAATAGTTCTTGGTGTAACTACAATAGGTTCTCATATTGCACCAGGATGTAGGAACCATTTTTGGTTGTAACAGAAGCTTTATTACATATTTATAGCTTTCCGTGCACTTTGGAGAAACTGACAGCGCTAACTGTTTAACTGTTGACAGCCCGGCAGTGGTATAATGGTTTTACCAAACTGCTGGACGTATATTTTCAGATTAAACATCTACATGCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2069
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056747 Nonsense 266 416 3 3
ENSDART00000056747 Nonsense 266 416 3 3
Genomic Location (Zv9):
Chromosome 2 (position 29766383)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 30068018
GRCz11 2 30051551
KASP Assay ID:
554-3388.1 (used for ordering genotyping assays)
KASP Sequence:
CGACAACGAGAAGGCAATTCATCGTCATCGAGACGTCAGAACCTTTCACC[A/T]AGCTCACCCTCACTGCCGCGCACCTAGTTTTCGTTGGAAACTCTTCWGCA
Long Flanking Sequence:
GTGTAAACAGTTTTACCAAACCAAAGGGATCAGGGAAAAGCACAGTCTGTAGGCTTGATTTAAATGACAATGTCTGATGACTTTGTGTAAATTCAGCAGCCAAAGTGACCAGACAAGCGTTTCAACACTTGCTTCTTGACAGTCATCACACGAGTTTGGATCAATTCCAAATCACCACCATTATGTCAAAACTTTGCCAAAGCATCGATTTTAGCAAAGTGCTTTATGAATATCTGCCAAAGATATCTATTTATTTGTGTTTGTATATCTTCTCAGAAAATTCAGTGGCTGCTAAATCAGGAGGATGTTTTCCTGGGTCTGGGACGGTGACACTTGGTGATGGGACGAGGAAACCCATCAAAGATCTTAAAGTGGGCGACCGGGTTTTGGCTGCAGACGAGAAGGGAAATGTCTTAATAAGCGACTTTATTATGTTTATAGACCACGATCCGACAACGAGAAGGCAATTCATCGTCATCGAGACGTCAGAACCTTTCACC[A/T]AGCTCACCCTCACTGCCGCGCACCTAGTTTTCGTTGGAAACTCTTCAGCAGCTTCGGGTATAACAGCAACATTTGCCAGCAACGTGAAGCCTGGAGATACAGTTTTAGTGTGGGAAGACACATGCGAGAGCCTCAAGAGCGTTACAGTGAAAAGGATTTACACTGAGGAGCACGAGGGCTCTTTTGCGCCAGTCACCGCGCACGGAACCATAATAGTGGATCAGGTGTTGGCATCGTGCTACGCGGTCATTGAGAACCACAAATGGGCACATTGGGCTTTTGCGCCGGTCAGGTTGTGTCACAAGCTGATGACGTGGCTTTTTCCGGCTCGTGAATCAAACGTCAATTTTCAGGAGGATGGTATCCACTGGTACTCAAATATGCTGTTTCACATCGGCTCTTGGCTGCTGGACAGAGACTCTTTCCATCCACTCGGGATTTTACACTTAAGTTGAGACTGCTGCTGTACATTATCACTATGTGGGACTCAAATGTATCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5719
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056747 Nonsense 266 416 3 3
ENSDART00000056747 Nonsense 266 416 3 3
Genomic Location (Zv9):
Chromosome 2 (position 29766383)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 30068018
GRCz11 2 30051551
KASP Assay ID:
554-3388.1 (used for ordering genotyping assays)
KASP Sequence:
CGACAACGAGAAGGCAATTCATCGTCATCGAGACGTCAGAACCTTTCACC[A/T]AGCTCACCCTCACTGCCGCGCACCTAGTTTTCGTTGGAAACTCTTCWGCA
Long Flanking Sequence:
GTGTAAACAGTTTTACCAAACCAAAGGGATCAGGGAAAAGCACAGTCTGTAGGCTTGATTTAAATGACAATGTCTGATGACTTTGTGTAAATTCAGCAGCCAAAGTGACCAGACAAGCGTTTCAACACTTGCTTCTTGACAGTCATCACACGAGTTTGGATCAATTCCAAATCACCACCATTATGTCAAAACTTTGCCAAAGCATCGATTTTAGCAAAGTGCTTTATGAATATCTGCCAAAGATATCTATTTATTTGTGTTTGTATATCTTCTCAGAAAATTCAGTGGCTGCTAAATCAGGAGGATGTTTTCCTGGGTCTGGGACGGTGACACTTGGTGATGGGACGAGGAAACCCATCAAAGATCTTAAAGTGGGCGACCGGGTTTTGGCTGCAGACGAGAAGGGAAATGTCTTAATAAGCGACTTTATTATGTTTATAGACCACGATCCGACAACGAGAAGGCAATTCATCGTCATCGAGACGTCAGAACCTTTCACC[A/T]AGCTCACCCTCACTGCCGCGCACCTAGTTTTCGTTGGAAACTCTTCAGCAGCTTCGGGTATAACAGCAACATTTGCCAGCAACGTGAAGCCTGGAGATACAGTTTTAGTGTGGGAAGACACATGCGAGAGCCTCAAGAGCGTTACAGTGAAAAGGATTTACACTGAGGAGCACGAGGGCTCTTTTGCGCCAGTCACCGCGCACGGAACCATAATAGTGGATCAGGTGTTGGCATCGTGCTACGCGGTCATTGAGAACCACAAATGGGCACATTGGGCTTTTGCGCCGGTCAGGTTGTGTCACAAGCTGATGACGTGGCTTTTTCCGGCTCGTGAATCAAACGTCAATTTTCAGGAGGATGGTATCCACTGGTACTCAAATATGCTGTTTCACATCGGCTCTTGGCTGCTGGACAGAGACTCTTTCCATCCACTCGGGATTTTACACTTAAGTTGAGACTGCTGCTGTACATTATCACTATGTGGGACTCAAATGTATCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25111
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000056747 Nonsense 364 416 3 3
Genomic Location (Zv9):
Chromosome 2 (position 29766088)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 30067723
GRCz11 2 30051256
KASP Assay ID:
554-7612.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTCATTGAGAACCACAAATGGGCACATTGGGCTTTTGCGCCGGTCAGGT[T/A]GTGTCACAAGCTGATGACGTGGCTTTTTCCGGCTCGTGAATCAAACGTCA
Long Flanking Sequence:
ATCAGGAGGATGTTTTCCTGGGTCTGGGACGGTGACACTTGGTGATGGGACGAGGAAACCCATCAAAGATCTTAAAGTGGGCGACCGGGTTTTGGCTGCAGACGAGAAGGGAAATGTCTTAATAAGCGACTTTATTATGTTTATAGACCACGATCCGACAACGAGAAGGCAATTCATCGTCATCGAGACGTCAGAACCTTTCACCAAGCTCACCCTCACTGCCGCGCACCTAGTTTTCGTTGGAAACTCTTCAGCAGCTTCGGGTATAACAGCAACATTTGCCAGCAACGTGAAGCCTGGAGATACAGTTTTAGTGTGGGAAGACACATGCGAGAGCCTCAAGAGCGTTACAGTGAAAAGGATTTACACTGAGGAGCACGAGGGCTCTTTTGCGCCAGTCACCGCGCACGGAACCATAATAGTGGATCAGGTGTTGGCATCGTGCTACGCGGTCATTGAGAACCACAAATGGGCACATTGGGCTTTTGCGCCGGTCAGGT[T/A]GTGTCACAAGCTGATGACGTGGCTTTTTCCGGCTCGTGAATCAAACGTCAATTTTCAGGAGGATGGTATCCACTGGTACTCAAATATGCTGTTTCACATCGGCTCTTGGCTGCTGGACAGAGACTCTTTCCATCCACTCGGGATTTTACACTTAAGTTGAGACTGCTGCTGTACATTATCACTATGTGGGACTCAAATGTATCTTTATTTTCTGTAAGAAAAGCCTTAAAGTGTTCATTGAATAATTTATTTCTATTGGATCACCTGTCTCTGGAAACGTACCCACCAATTCAAGCATGATGTGACCGTTTTTGTGTGCGCATTTTGTGAAACATACAAGAGATTATATGAGATATGAGAAAGCGCAGGGCTGTGCAGTGTGCAGCGCTCTATTTTATCGGATAACCATAAAGGATGGCGCTCAAAAGTTATATTTTTGTACTCAGATTTGTATATTAGATTTTTGATGGCTCTAAAAGCATTTCCAGTATCACATTTCG
Associated Phenotype:
Not determined