Busch Lab

ZMP

srrm2

Ensembl ID:
ENSDARG00000037965
ZFIN ID:
ZDB-GENE-050522-399
Description:
Srrm2 protein [Source:UniProtKB/TrEMBL;Acc:Q6IQN3]
Human Orthologue:
SRRM2
Human Description:
serine/arginine repetitive matrix 2 [Source:HGNC Symbol;Acc:16639]
Mouse Orthologue:
Srrm2
Mouse Description:
serine/arginine repetitive matrix 2 Gene [Source:MGI Symbol;Acc:MGI:1923206]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa12827 Essential Splice Site Available for shipment Available now
sa2088 Nonsense Available for shipment Available now
sa14000 Nonsense Available for shipment Available now
sa33218 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa9943 Nonsense Available for shipment Available now

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3445
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055337 Essential Splice Site 83 643 3 10
ENSDART00000129339 None None 1168 None 11
ENSDART00000129377 Essential Splice Site 83 1282 2 13
Genomic Location (Zv9):
Chromosome 3 (position 32772874)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 32504184
GRCz11 3 32635898
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTACAAATTGAAGAGAATTTTAGGGTGATCTGACTAGTACTTTTGTGGCA[G/A]TTACTCTGCAGAGGAGATTGAAGAGAAGGTCAACACCTTTCGTTTGATGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12827
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055337 Essential Splice Site 177 643 4 10
ENSDART00000129339 Essential Splice Site 63 1168 1 11
ENSDART00000129377 Essential Splice Site 177 1282 3 13
Genomic Location (Zv9):
Chromosome 3 (position 32774586)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 32505896
GRCz11 3 32637610
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGGAGCAGGAGAGACTGGAACGMGAGAAGCAGCAGCAGCAACAGTAYCAG[T/C]GAGTAGACAGAGAAGAGATTAAAGGGGTGCTATCATGAAAAAKCACTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2088
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055337 Nonsense 548 643 10 10
ENSDART00000129339 Nonsense 434 1168 7 11
ENSDART00000129377 Nonsense 548 1282 9 13
Genomic Location (Zv9):
Chromosome 3 (position 32779328)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 32510638
GRCz11 3 32642352
KASP Assay ID:
554-2515.1 (used for ordering genotyping assays)
KASP Sequence:
CACCTTTCGCCAATGGAAGACAGAAAGAACGAGAACTGGAGAAGGAAAGA[C/T]AAGAACAGCGAGACAGGGAGAAAAGACGAGAGGAGGAGATGAGGGAAGAA
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
sa14000
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055337 None None 643 None 10
ENSDART00000129339 Nonsense 747 1168 7 11
ENSDART00000129377 Nonsense 861 1282 9 13
Genomic Location (Zv9):
Chromosome 3 (position 32780267)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 32511577
GRCz11 3 32643291
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGCTGGAACAAGAGTCGTYACKTCCTTCACCTAGCAGAGGAAGAGATCGA[C/T]AGAGTGACCAAAGGAAAGAGGCACCGCCTTTGTCTCCAAGAGAAAAAGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33218
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055337 None None 643 None 10
ENSDART00000129339 Essential Splice Site 862 1168 7 11
ENSDART00000129377 Essential Splice Site 976 1282 9 13
Genomic Location (Zv9):
Chromosome 3 (position 32780615)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 32511925
GRCz11 3 32643639
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGAGGAACAGCAGATCAAGGAGTCCCCGAAGACCGAGTCCTCCGTACAGG[T/C]TAGTCAGATGACCAGGTTTTGGAAATGCAAGAGGCAATGGAGACTGTAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9943
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000055337 None None 643 None 10
ENSDART00000129339 Nonsense 1023 1168 8 11
ENSDART00000129377 Nonsense 1137 1282 10 13
Genomic Location (Zv9):
Chromosome 3 (position 32784233)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 32515543
GRCz11 3 32647257
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCGGGAGGTCGGTTAAGAAGGCAATCCCCAACATCWGTTCATGARCCAT[C/A]AGCAAGAGGAAAGACTGCAGTAAACGGGAAATCAGAGAAAGAGAGCTCTG
Associated Phenotype:
Not determined