ZMP

arhgef3l

Ensembl ID:

ENSDARG00000037554

ZFIN ID:

ZDB-GENE-050522-85

Description:

Rho guanine nucleotide exchange factor (GEF) 3, like [Source:RefSeq peptide;Acc:NP_001018563]

Human Orthologue:

ARHGEF3

Human Description:

Rho guanine nucleotide exchange factor (GEF) 3 [Source:HGNC Symbol;Acc:683]

Mouse Orthologue:

Arhgef3

Mouse Description:

Rho guanine nucleotide exchange factor (GEF) 3 Gene [Source:MGI Symbol;Acc:MGI:1918954]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa7504	Missense, Splice Site	Mutation detected in F1 DNA	Not yet available
sa45000	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa7504

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Missense, Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000054686	Missense, Splice Site	85	506	5	12
ENSDART00000127445	Missense, Splice Site	111	532	6	13
ENSDART00000138936	Missense, Splice Site	90	511	5	12

Genomic Location (Zv9):

Chromosome 23 (position 20963885)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	20748992
GRCz11	23	20675335

KASP Assay ID:

554-4283.1 (used for ordering genotyping assays)

KASP Sequence:

TATTTGTGTTACATTTGTGTRTGTGTTTGTGCTTGGATTTTACTCCTCAG[C/T]GTTCTATCAGTTTCCGRACAGAGGCCCGGCCATTGCCTCCAATGCCAAGA

Long Flanking Sequence:

TGTGCTGTCAAACGAATAAAGATCTTTTCTTAATTTGCTGGTGTTTTTTGCAATCAGCCACCATAAAAAATATATTCAAAATATTAAAATATTAATTAGTATTTAAAAACATTATATGTATAAACTGAAATATATAATAAGGTATAAAATACCATGCTTACATCAACATAACGTAACCTAACACAACACAACACAACACAGCATAACGTAACGTAACATAACGTAAATATATGTTATGTATAATTAAATATGATGAAGACCTCTAGTGAGTCCCAGTTGGTGTACTTCTATGCTGTTTTTTTTTTTGTATAAAAAATGCAAATATTGAATTGATACAGACAAACCCAAAAAGAAACATATATATATTTAAATACCCAGATATTTCATTTAACAAAAACAAACAAAAAAAGTGTGCATAGTCTGTGAGTGTGTGTTGTGTCATTTGTGATATATTTGTGTTACATTTGTGTATGTGTTTGTGCTTGGATTTTACTCCTCAG[C/T]GTTCTATCAGTTTCCGAACAGAGGCCCGGCCATTGCCTCCAATGCCAAGATCCCGTCAAAAGGCTTCTTCATTCCCTCGACGGCGGAGCAGTCAGCTGTGGAGTGACACGGTGGACAACATGAGCCATGAGCTCAGCACTAAAGAGATCAAACGACAAGAGGTGTGATAACAGCGTTAGATTAATGCCACAACACAGACTAATGTGTCAAAGTCAATTCTTTATTTTGTGCATTTTGTAATTCTAAATTACCTTACAGATTATATTTATCATATTTGGCCTTTAATTACGAGCATCAAACTAGTAACTTTGGCCCATGCACCTTTAAATTCTTTTAAAAAAGCTTTCTGTCTTTACAACCGTAGTTGTGAAACAGGAAGTGAGCTGGTATACGAGGCCATGTTCTCTATTTCAGTGTCAGTATTTCCTCTGAAACACAAGCTCTACCACACAGCACTGCCAAACTGACTGGTAACTTGTGACAGTAGTGCAGTTATAAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa45000

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000054686	Essential Splice Site	159	506	6	12
ENSDART00000127445	Essential Splice Site	185	532	7	13
ENSDART00000138936	Essential Splice Site	164	511	6	12

Genomic Location (Zv9):

Chromosome 23 (position 20964559)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	20749666
GRCz11	23	20676009

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AACCCAGGGTGAGAAACAGCTCATAGAGGATCTAAGCCTCGTAAAAAAGG[T/A]TCGTCCAGGAGTTCAGCTGATTTATTTATTTCTACTGTCCTAAATGAGAA

Long Flanking Sequence:

CGTTAGATTAATGCCACAACACAGACTAATGTGTCAAAGTCAATTCTTTATTTTGTGCATTTTGTAATTCTAAATTACCTTACAGATTATATTTATCATATTTGGCCTTTAATTACGAGCATCAAACTAGTAACTTTGGCCCATGCACCTTTAAATTCTTTTAAAAAAGCTTTCTGTCTTTACAACCGTAGTTGTGAAACAGGAAGTGAGCTGGTATACGAGGCCATGTTCTCTATTTCAGTGTCAGTATTTCCTCTGAAACACAAGCTCTACCACACAGCACTGCCAAACTGACTGGTAACTTGTGACAGTAGTGCAGTTATAAATGTGTGTGTATGCATGTTTGCGGTCTTCCTGCACAAGGTTTCATAAGGTTACAACTACCTGTGCACATTTTCCTGTGCATTAATGTAATATTTATTCTCTTCATCTCCAGGTAATCTACGAATTAACCCAGGGTGAGAAACAGCTCATAGAGGATCTAAGCCTCGTAAAAAAGG[T/A]TCGTCCAGGAGTTCAGCTGATTTATTTATTTCTACTGTCCTAAATGAGAAGGATTTTAATTTGGACTGTTCTCTCAGGTGTACTATGAGCCTATGCTGAAGTTAGACATCATGACAGAAAGTGAGCTGGGACAGATATTCGGGACGCTTGATTCTTTAATTCCCCTTCATGAAGGTAAATGTTTCTTTGAGAATGTTTCTTCATTTATTCACTAAGGCCTTCTTTCAGATGTACATAACAAATTTTTAATTAGATACCCAAGTCTCGCAGTCATTGACTTTCACTGGAATTGTGTCATTTAACAGACCCTTGTTGATAAAACTAGGTTAAATACTGGGCTTTTATAGCTATAAGAACCAGCAGATCAAATTATCCTAATGTGTTTATTTTCATGAAACTTAAATTTCCTTATTATGGTGGGCATATCCTTTATTTTCACATCCCAATGTTGACAGGTATGATTGTTCAACCATGACACATACCTACTAGAGACATTAATC

Associated Phenotype:

Not determined