ZMP
si:ch211-145b13.4
Ensembl ID:
ZFIN ID:
Description:
Si:ch211-145b13.4 protein [Source:UniProtKB/TrEMBL;Acc:A0JMC0]
Human Orthologue:
TOPORS
Human Description:
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:2
Mouse Orthologues:
4930547C10Rik, Topors
Mouse Descriptions:
RIKEN cDNA 4930547C10 gene Gene [Source:MGI Symbol;Acc:MGI:1915524]
topoisomerase I binding, arginine/serine-rich Gene [Source:MGI Symbol;Acc:MGI:2146189]
topoisomerase I binding, arginine/serine-rich Gene [Source:MGI Symbol;Acc:MGI:2146189]
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa19504 | Essential Splice Site | Available for shipment | Available now |
| sa19505 | Nonsense | Available for shipment | Available now |
| sa19506 | Missense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa19504
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000102379 | Essential Splice Site | None | 833 | None | 4 |
| ENSDART00000121658 | None | None | 791 | None | 4 |
| ENSDART00000127154 | None | None | 490 | None | 2 |
| ENSDART00000129269 | Essential Splice Site | None | 999 | None | 3 |
| ENSDART00000141661 | Essential Splice Site | None | 154 | None | 3 |
Genomic Location (Zv9):
Chromosome 1 (position 24987923)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 25411621 |
| GRCz11 | 1 | 26105335 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCCGATTGTCGCGTAATGATCTTTAAACCAGCACGATTGTGTTAGACAG[T/G]AAGTTACATTATTTCAGGTCATCGTGATTTTAAGAATTCTGTAATACACT
Long Flanking Sequence:
CTGTTTTAAAAAATGTGCTAAAAAACTAAGTGTTTATTTTGGCTTCATTGTGAAGTTACAATTTACCTGTATATAAGAGTATATTCTTGAATTTACTCTACACGTTGCAGATTGTTTTTCAACTATTCTTAAACGTTTCTGAGAGCGTTCTTGTTTAAATGTATTTTAATCAAAAAGCATTCGTATAGATTTTTGGTCACTTTGAAAACCTTTGTTTTAGCGCACGGGTAATGTGCTTTTATTATGAAGCAAAAAACCGGAAGAATTGAAAATTTGATGCAGTTTACTTCCGCAATGTTCTGTTTTGTTACGTCATTATCAACACTGCTGATATAGACCGACTGAGAGAAGTTCATCGTTTTTGGTCGTCAATAAGTCTTTTTTATATTTTTTAAACAAGTTGTCAAACGAGTAACAATAAAATCCATCATAGACGATGCATTTCAGGATACCCGATTGTCGCGTAATGATCTTTAAACCAGCACGATTGTGTTAGACAG[T/G]AAGTTACATTATTTCAGGTCATCGTGATTTTAAGAATTCTGTAATACACTTTTAAAACAGTACAACTCCTAATGCTTTCTTGTTCGTTCCAAATATAAAGCGAGATGCTTCTGGCGGATTTAAGAGGATCTAAGAACTTCAAAAGTTTCAACGAATACACGAACGAGTAAGTTTAAAAACATTTTCAATGAGATGTGTAAAAAGTCATTTTCATAGCGATTTGTTATAGAAATGTATTGTTTCTATTAAAACACGAGCTAAAATTACACTGCAGAGACTTTTCAGTAAACACAAACACTAAATATACAGGCATTATGTTGTATATAGACTTTGTAATATGAATAAACATATTCTGATAAAAACTAATGTTATTGCTCTTTATGTAATCATATTTATACACGCACTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTGTGGGTCACTATGGTTTAAAATGTTTATAAGCGTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19505
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000102379 | Nonsense | 182 | 833 | 3 | 4 |
| ENSDART00000121658 | Nonsense | 166 | 791 | 1 | 4 |
| ENSDART00000127154 | Nonsense | 182 | 490 | 1 | 2 |
| ENSDART00000129269 | Nonsense | 182 | 999 | 3 | 3 |
| ENSDART00000141661 | None | None | 154 | None | 3 |
Genomic Location (Zv9):
Chromosome 1 (position 24989778)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 25413476 |
| GRCz11 | 1 | 26107190 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGCGAAGTCTTCAAGATCAAGAAGTGGTTAAGTTCAGACGAGCCTTGTA[C/A]AGAAGAGGTGTGCAGGTCCAAAGCGTGCAGGATGGTGGGCGTACGAGAGA
Long Flanking Sequence:
AACACAATCTCAAAAGGAGCATCTCCAGAATCAAAATGCCCAATCTGCCTGGATCACTTTAAAAACATATCATATCTTGATGTGTGCCTTCACAAGTTCTGCTTCTGCTGCATCCATGAATGGTCCAAGAACAAAGCTGAATGCCCTTTATGCAAACAGCCATTTAATTCATTCTATCACACTATTAAGTCTGAAGATGACTACAAGAGGTTTGACCTGCGACCAACTGAAAATGGCTCATTTGGAAACATGGCAGGGCAAAGATTCAGGTATCGCACCACGCTTACAGGTGACCGCAGACCAGTACAGAGGCGAACGTCTCCTCCTCCCGACCATGGGATCATATTTGAGGGTCTGAGAGGATCTCTTCCACAACGGCACAACAGAGATCTACATAGCATGATCAGGAGGCTGACAGTAAGGCAGAGAAGAGAGAGTGAGGGTAGGTCTTTGCGAAGTCTTCAAGATCAAGAAGTGGTTAAGTTCAGACGAGCCTTGTA[C/A]AGAAGAGGTGTGCAGGTCCAAAGCGTGCAGGATGGTGGGCGTACGAGAGAGACCTCAGCAGAGTTCTTCAAAAGAAATCCTGCTTGCCTCCACAGGCTTGTACCTTGGCTGAGACGAGAACTGACTGTTCTGTACGGTGCTCATGGTTCTCTGGTCAACATTGTGCAGCACATCATTATGACTCTGATCACTCGACATAACTTGGACGACCAGGCTGTTCAACATGAGCTTCGGCCCTTCTTACTGTCCCACACAGAGCACTTCTTACATGAGTTTCTCAGCTTTGCTCGATCGCCGTTCAATATGGAGGCATATGACCAACGTGCTGTTTATGACTTGCCAAGACCTTCAGGAGAAAGTAGCAGTTCGGAAAACTCTGTGATCGCCATCTCTGAGGATGAGAGCGAATCTTTAGTGTCAGGAGCCCAGGATTTTGCCACTCCTAGGGTGACCTCAAGCCAAACAGCATGGGATGATGAGACTCCAGGACCATCCTACTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19506
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > G
Consequence:
Missense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000102379 | Missense | 651 | 833 | 4 | 4 |
| ENSDART00000121658 | Missense | 636 | 791 | 3 | 4 |
| ENSDART00000127154 | None | None | 490 | None | 2 |
| ENSDART00000129269 | Missense | 685 | 999 | 3 | 3 |
| ENSDART00000141661 | None | None | 154 | None | 3 |
Genomic Location (Zv9):
Chromosome 1 (position 24991286)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 25414984 |
| GRCz11 | 1 | 26108698 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGGCATAATAGAAGTTGTTCAAGGAGTTATTCAAGAACAAGCCCATTTA[A/G]TGAACGGAATAGAAGACACTCAAGGAGTAATTCTAGAAAAAGCCAATCCA
Long Flanking Sequence:
AGAGAGCAAGAATAAGCAGAGAGGGGAAAAGGAAACAAGTCGTCACTCTTCATCCTATTGGCATTCTTATAGCTATTACAGTCATGACAACAGCAGAAAAGCTTATACAGAAACAAGCTCATCTTATACAAGCTACTACAGAAGTGTAAATGATCAGTTTGGTTCTCGATCACACGGCAAAAGAAGATGTAGGGACCTTCTGGACAGAAGTCGCTCAAGGAGTAATTCAAGAATAAGCCAGTCGAATCGGCGTAATAGGAGTCGCTCAAGGAGTAATTCAAGAATAAGCCGGTCCAATCAACGGAATAGAAGTCACTCAAGGAGTAATTCTGGAAAAAGCCAATCCAATCGGCGTAATAGAAGTTGTTCAAGGAGTTATTCAAGAACAAGCCCATTTAATGAACGGAATAGAAGACACTCAAGGAGTAATTCTAGAAAAAGCCAATCCAATCGGCATAATAGAAGTTGTTCAAGGAGTTATTCAAGAACAAGCCCATTTA[A/G]TGAACGGAATAGAAGACACTCAAGGAGTAATTCTAGAAAAAGCCAATCCAATCGGCATAATAGAAGTTGTTCAAGGAGTTATTCAAGAACAAGCCCATTTAATCAACGGAATAGAAGACACTCAAGGAGTAATTCTAGAATAAGCCAGTCCAGTCGGCAGAACAGAAGTCTCTCAAGGAGTAATTCTAGAAAAGGCTATTCAAATCGGCGGAACAGAAATCATTCTAGGAGTAGTTCTAGAGTAAGCCAGTCCAGTCAGCGGAACAGAAGTCACTCAAGGAGTAATTTTAGAATCAAGTCTAGCTCCTACAAAAGTCAAGATGAAAAATATCAAAGAAGCCTTTCTAGATCCCTTTACTCCAATAATGATGTCAGAAGTCGCTCAAGAAGCAGTTCCAGAATAAACACCTCTAGCCGCCAGGACCGAAGACGCTCAAGGAGCAGTTCTAGAATGAATTCCAGCTCCTCACGCCAGACATCATGCCACGATAAATATGGTA
Associated Phenotype:
Not determined