ZMP

aldh8a1

Ensembl ID:

ENSDARG00000036776

ZFIN ID:

ZDB-GENE-040912-3

Description:

Aldehyde dehydrogenase family 8 member A1 [Source:UniProtKB/Swiss-Prot;Acc:Q66I21]

Human Orthologue:

ALDH8A1

Human Description:

aldehyde dehydrogenase 8 family, member A1 [Source:HGNC Symbol;Acc:15471]

Mouse Orthologue:

Aldh8a1

Mouse Description:

aldehyde dehydrogenase 8 family, member A1 Gene [Source:MGI Symbol;Acc:MGI:2653900]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa3225	Nonsense	F2 line generated	Not yet available
sa44022	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa3225

Status:

F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000053399	Nonsense	315	487	6	7

Genomic Location (Zv9):

Chromosome 23 (position 31994747)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	31829637
GRCz11	23	31756168

KASP Assay ID:

554-2957.1 (used for ordering genotyping assays)

KASP Sequence:

GCGTTTACCCAGAATTCCTCACTCGTTTTGTGGAGGCGACTCGTCGGTGG[A/T]AAACCGGGGTTCCTTCAGACCCCTCAAATGACAATGGAGCACTCATWAGC

Long Flanking Sequence:

GTGTACATACTGTACATATCAACACAAGAAGGACATCTAAATAAAAGTAAAATAAAGTAAACAATTACAATTCTGAAGTTTATTGTTGATAAGATCATTACTGTTTATGTCATACGTTTTTCACATTTACTTTATTTGTCTTAAACTAATTGAGATGACTTTATATAATTCCCTTTCTCGCCACTATGTGGTGCTCAAAATACATATTTTGTTAATCCAGCTACGTACACTATGTTCCCAAAACTCTCTCTCTCTTTCTCTCTTAGGCCTTCATTCACATTACTCACACAGACACATCATCATCACTGTGCTAATATTTAAACTGTATCCTCATAATTCACACAGCCCAATGAAAGTTGTGAGATTTACTCAACAACTCATTTGCATGTTCTTCTCCACTCTCTCAGGGTGAGATCTGCCTGTGTACCAGCCGCATCTTTGTGGAGCGGAGCGTTTACCCAGAATTCCTCACTCGTTTTGTGGAGGCGACTCGTCGGTGG[A/T]AAACCGGGGTTCCTTCAGACCCCTCAAATGACAATGGAGCACTCATTAGCAAAGAACATCTGCAGAAGGTACGGTTATAATCACACACGCAATCCTATTGATACTACATGCTATCTGTATATGATATGATATCTACACAACCAGTTAAAAGTTTGGGATAAGTAAAAATAATATATATGAACATTATTATAAAATATGTAATATTATTGTAATTTAAAAAAACTGTTTTCATATAGAAAGTAGTTTAAAATGTGAATTATTGCTCTGGTTTAAATTGAGTTGATTTTTCAGTAGGTCTATCATTACTCCAGTCTTGAGTGTCACATGATAATAAATCATAAATCATCCCAATAAGATGCTTTGCTCTTTAGGAAACTCTTGCTCTTTTGTTATTATTTGATTTTTTAAACATTTCTGTTGTGTTGCTTAATATATTATAGAATCTTTTTTTAATTAGGAAATAGAAGAATATAGGAAATTGTAAGACATATAAGGAAATA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa44022

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > T

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000053399	Essential Splice Site	337	487	6	7

Genomic Location (Zv9):

Chromosome 23 (position 31994678)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	23	31829568
GRCz11	23	31756099

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

ACCCCTCAAATGACAATGGAGCACTCATTAGCAAAGAACATCTGCAGAAG[G/T]TACGGTTATAATCACACACGCAATCCTATTGATACTACATGCTATCTGTA

Long Flanking Sequence:

ATTCTGAAGTTTATTGTTGATAAGATCATTACTGTTTATGTCATACGTTTTTCACATTTACTTTATTTGTCTTAAACTAATTGAGATGACTTTATATAATTCCCTTTCTCGCCACTATGTGGTGCTCAAAATACATATTTTGTTAATCCAGCTACGTACACTATGTTCCCAAAACTCTCTCTCTCTTTCTCTCTTAGGCCTTCATTCACATTACTCACACAGACACATCATCATCACTGTGCTAATATTTAAACTGTATCCTCATAATTCACACAGCCCAATGAAAGTTGTGAGATTTACTCAACAACTCATTTGCATGTTCTTCTCCACTCTCTCAGGGTGAGATCTGCCTGTGTACCAGCCGCATCTTTGTGGAGCGGAGCGTTTACCCAGAATTCCTCACTCGTTTTGTGGAGGCGACTCGTCGGTGGAAAACCGGGGTTCCTTCAGACCCCTCAAATGACAATGGAGCACTCATTAGCAAAGAACATCTGCAGAAG[G/T]TACGGTTATAATCACACACGCAATCCTATTGATACTACATGCTATCTGTATATGATATGATATCTACACAACCAGTTAAAAGTTTGGGATAAGTAAAAATAATATATATGAACATTATTATAAAATATGTAATATTATTGTAATTTAAAAAAACTGTTTTCATATAGAAAGTAGTTTAAAATGTGAATTATTGCTCTGGTTTAAATTGAGTTGATTTTTCAGTAGGTCTATCATTACTCCAGTCTTGAGTGTCACATGATAATAAATCATAAATCATCCCAATAAGATGCTTTGCTCTTTAGGAAACTCTTGCTCTTTTGTTATTATTTGATTTTTTAAACATTTCTGTTGTGTTGCTTAATATATTATAGAATCTTTTTTTAATTAGGAAATAGAAGAATATAGGAAATTGTAAGACATATAAGGAAATAAATAGTGTTGGTCTTTTCATAAAATAATTCTAAAAAGTAATATATATCACAGTTTTCAGGAAATTATGA

Associated Phenotype:

Not determined