Busch Lab

ZMP

si:ch211-102c2.6

Ensembl ID:
ENSDARG00000036481
ZFIN ID:
ZDB-GENE-030131-4648
Description:
transcobalamin-2 [Source:RefSeq peptide;Acc:NP_001116703]
Human Orthologues:
GIF, TCN1, TCN2
Human Descriptions:
gastric intrinsic factor (vitamin B synthesis) [Source:HGNC Symbol;Acc:4268]
transcobalamin I (vitamin B12 binding protein, R binder family) [Source:HGNC Symbol;Acc:11652]
transcobalamin II [Source:HGNC Symbol;Acc:11653]
Mouse Orthologues:
Gif, Tcn2
Mouse Descriptions:
gastric intrinsic factor Gene [Source:MGI Symbol;Acc:MGI:1202394]
transcobalamin 2 Gene [Source:MGI Symbol;Acc:MGI:98534]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa16018 Nonsense Available for shipment Available now
sa33607 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa45202 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa40433 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa16018
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053001 Nonsense 67 423 3 10
ENSDART00000145631 Nonsense 67 245 3 6
ENSDART00000145736 None None 180 None 5
Genomic Location (Zv9):
Chromosome 5 (position 28443360)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26198658
GRCz11 5 26798811
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCGCTCTGCGGCTCTCCACACAACATAACCTGGACAAAGAAAACCAATA[T/A]CTCAACCGCCTCAAGAAAGAGTTTCAYGAGGATATTGARAAGTACAAATC
Long Flanking Sequence:
GTTTAGGAAGTTCCAATGAAATGGTGAAGTTATAAATCTGCCTGAAAGACCACATCTTACTGTATTGGTAAATATTCTTAAAGGATTACAACTAGGAAGTTGCAGAATATAAGAGACGCTCTCTAACAAGACCTTAATGATCAATCCATCCCACCACTCACCCATATGTTCAATTATTTTATTTCAATAAAAGTTATGATTTTTAGTTAGATTTTTTTAAACAAGAGAAATAAAGGATCAACTATACATATTTATTTTCACAACCTGTTCATATTTACAAAGGTGCCAATATTTTTGACCAAGTCTGTCTGACTGCATGAAATTTCTTACTCTCTGTTTCTTTTTCTAATACCATCAGCATCAGATCACGAAACTCTTCTCCAGTCGCTCAATAAGCAGCTTCTGCGCTCTGTGGACACACAAGACAACCTGCCCAATCCCAGTGTGCACATCGCTCTGCGGCTCTCCACACAACATAACCTGGACAAAGAAAACCAATA[T/A]CTCAACCGCCTCAAGAAAGAGTTTCATGAGGATATTGAGAAGTACAAATCTTTTCAGCTTCAACTTTAAAGCAGCAGTTTCTTATTTCGTTATTTGTTCTTTAAATGTTCAATAGCTTTTGATTCTCTAAATAACATACAGTAATGTTCGGGAATTATTGTATCTGTTACAGTCACATGAGTTGTGTCATTATGCATAAATATAGACTTTTCTATAATTCTACTTCATTTTTCTGCTTTAATTTAATTGCCTTTTGTTCCACTACACTTCTTGTAGATCTCTGAGAAATGGTGAGTTGGTGGTTGGCCGTCTCGCCCTGTACATCTTGGCCTTGAGGTCCTCCTGTCACGATCTGAGTTTACACCTCAATCACAATGAGAAGAATGAGTTCCTCCTAACTCACCTTAAGAAAGAAATGGAGGAAGAGAAACAAAACATTGCATGTGAGAGCAATTTCTTTATGACACAATTTTTTAATCACATCATTTGGGGTTGGTAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33607
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053001 Essential Splice Site 81 423 3 10
ENSDART00000145631 Essential Splice Site 81 245 3 6
ENSDART00000145736 None None 180 None 5
Genomic Location (Zv9):
Chromosome 5 (position 28443402)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26198700
GRCz11 5 26798853
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACCAATATCTCAACCGCCTCAAGAAAGAGTTTCATGAGGATATTGAGAA[G/A]TACAAATCTTTTCAGCTTCAACTTTAAAGCAGCAGTTTCTTATTTCGTTA
Long Flanking Sequence:
TGAAAGACCACATCTTACTGTATTGGTAAATATTCTTAAAGGATTACAACTAGGAAGTTGCAGAATATAAGAGACGCTCTCTAACAAGACCTTAATGATCAATCCATCCCACCACTCACCCATATGTTCAATTATTTTATTTCAATAAAAGTTATGATTTTTAGTTAGATTTTTTTAAACAAGAGAAATAAAGGATCAACTATACATATTTATTTTCACAACCTGTTCATATTTACAAAGGTGCCAATATTTTTGACCAAGTCTGTCTGACTGCATGAAATTTCTTACTCTCTGTTTCTTTTTCTAATACCATCAGCATCAGATCACGAAACTCTTCTCCAGTCGCTCAATAAGCAGCTTCTGCGCTCTGTGGACACACAAGACAACCTGCCCAATCCCAGTGTGCACATCGCTCTGCGGCTCTCCACACAACATAACCTGGACAAAGAAAACCAATATCTCAACCGCCTCAAGAAAGAGTTTCATGAGGATATTGAGAA[G/A]TACAAATCTTTTCAGCTTCAACTTTAAAGCAGCAGTTTCTTATTTCGTTATTTGTTCTTTAAATGTTCAATAGCTTTTGATTCTCTAAATAACATACAGTAATGTTCGGGAATTATTGTATCTGTTACAGTCACATGAGTTGTGTCATTATGCATAAATATAGACTTTTCTATAATTCTACTTCATTTTTCTGCTTTAATTTAATTGCCTTTTGTTCCACTACACTTCTTGTAGATCTCTGAGAAATGGTGAGTTGGTGGTTGGCCGTCTCGCCCTGTACATCTTGGCCTTGAGGTCCTCCTGTCACGATCTGAGTTTACACCTCAATCACAATGAGAAGAATGAGTTCCTCCTAACTCACCTTAAGAAAGAAATGGAGGAAGAGAAACAAAACATTGCATGTGAGAGCAATTTCTTTATGACACAATTTTTTAATCACATCATTTGGGGTTGGTAACACTCTGTATTGTTTTTGAAAGACGTGTAATGCTTAGAAAAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45202
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053001 Essential Splice Site 245 423 None 10
ENSDART00000145631 None 245 245 6 6
ENSDART00000145736 Essential Splice Site 162 180 None 5
Genomic Location (Zv9):
Chromosome 5 (position 28446937)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26202235
GRCz11 5 26802388
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCTGATGGTCACATGGGCAATGAATTCAGCACGGGCTTGGCAGTGCAGG[T/C]AATAGGAATAAAATGAAATCCATTTATTCATTTATTTTCCTTCGGCTTAG
Long Flanking Sequence:
GTTGTTTTTGTTTTTTTCATGTATCGTCTGTCCTTGATTTTACTGTTGACCAGATGACGGAAAAAAAATCTGATAGTGATTCAGTTATATTATTCTTGGACTCCGCTAACAGTATTTAAAAAAAATTTTTTATCATAATTGAAATATTGTCATCTTTTGTTTGAGAACATGTAAGGCATCAAATTTAAACAAATGGCAAATAATTGTGAAAATATCCAATATAATTATATTTTAAGTCTGCTGAAACAGAAATGTAAATGTGGAAATTTGTTTAAATGTCTTGAAGTGAACACCTAACAAATGTTACTTCTCTTATTGCCCTTCAGACTCACATGCGATGGCAGGCATGGCCCTGCAGTGTCTAAAAAATGAGGGAATCTCGGTTAAAGATGAAGCTGAGCTGGACAAAGCTTTGGCTACCATTAAGCAGAAGCTTGTAGACTCTAAACGAGCTGATGGTCACATGGGCAATGAATTCAGCACGGGCTTGGCAGTGCAGG[T/C]AATAGGAATAAAATGAAATCCATTTATTCATTTATTTTCCTTCGGCTTAGTCCCTTTATTCTCAGGGGTCGACAAATGGGAATGAACCGGCAACTCATCCAGCATATGATTTTACACTGCGAATGCCCTTCCATCTGCAACCCAGTACTGGAAAACATACACACTCATTCACACACATACAAATGCCTGTACCGCATGTCTTTGGATTGTGGGGGAAACCGGAGCACCCAAAGGAAACCCACACAAACACAGGGAGAACATGCAAACTCAACACAGAAACGCCAACTGACCCAGCCAGGACTCAAGCCAGCGACCTTCTTGCTGTGAGGCGACAGTGCTAACCACTAAGCCACCTTGTCGCTATAAAATTAAATTATAAAGTGAACAATTATGAAGTGAAAAAAATTCTTATCTGAGTGACAGATACTCATAATTCTTGGTCTTTTAGGCCTTGTTGGCTATGGGAGTTGAGATGGAGGAATGCGGCACTGCTATCGAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40433
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000053001 Nonsense 372 423 9 10
ENSDART00000145631 None None 245 None 6
ENSDART00000145736 None None 180 None 5
Genomic Location (Zv9):
Chromosome 5 (position 28449952)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 26205250
GRCz11 5 26805403
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCACAATTTTGCTTTCTGCATGACAGCTTTAAGACTGAAGACAGCTTGTG[G/A]GGAGCTTTTCTCAGTGTGCTCAATGATGAGCAAGCCCGTCAGACTGATCG
Long Flanking Sequence:
AACAGAAATTGTGGAAAATAAATAAACAGAGGGGCTAATAATTCAGGGGGGCTAATAATTCTGACTTCAACTGTATATTTATAAAACAAAAATTGTATTTAGTTTTAAAACATTATATTGAGTATTTTAATGTGATACATTATACTGTATTAAATGTTTTATTTGATTTTTAGAACTTTGATGTCCTTGTTTCAGACACTCTTACTGCTGATGTTGAATCGGCTTCAGAGGTTCTCCCAAGTCTCGGACAAGTGGCTGTACAAGTGGAGGTTATAAAATCCAATGGGGAAGCGTCTGTGTTTCCCATTAATGTCCCCAAAGGCTCCTCTCTGTTTGAAGCCCTGAACCTTCTTCAAGACAAACAAACTGGTTTCACGTGAGTTTGAATTACTCAATTTACATTTTTTTAAAAATATTTCACCATTTAACTGCAGTTTTCCTTTTTTACATGCACAATTTTGCTTTCTGCATGACAGCTTTAAGACTGAAGACAGCTTGTG[G/A]GGAGCTTTTCTCAGTGTGCTCAATGATGAGCAAGCCCGTCAGACTGATCGCAGATACTGGCATGTTTCCTCAGATGGCACCTCTCTGACACAGGGTGAGATGCAATAAATGTGTTTTACGTTAAAATAGGTGCATGTCTTTACAAATGATTTGCATAAGTCTGATTCATTTCTTTTATCTGCAATGTTGTGTTTTTGTTCTCAGGTATTAAAGACTATAAGATTGACTCAGCTCAGCGCATCACCATTAAAAACACTGGCTACTGAGTCTTCTGCTGGATGCAGGGGAGGAGATGAATTGGATGAAACCATAATATGTTTATGAATTCTACTGATATTAATTGTCATTGATTTTATTTCTAATTACAAACAACTGTCTGTTTGACTAAAAAACGTGCTGTTTACCCTAAAATAACATCAGGAAAATAAGTAGTTTTTTATTGTTTAACATAGATTCATGTCTTTGAACTCTAACACATCTTTACCTGTTAATCCCCAGCA
Associated Phenotype:
Not determined