ZMP
cars
Ensembl ID:
ZFIN ID:
Description:
cysteinyl-tRNA synthetase, cytoplasmic [Source:RefSeq peptide;Acc:NP_001112372]
Human Orthologue:
CARS
Human Description:
cysteinyl-tRNA synthetase [Source:HGNC Symbol;Acc:1493]
Mouse Orthologue:
Cars
Mouse Description:
cysteinyl-tRNA synthetase Gene [Source:MGI Symbol;Acc:MGI:1351477]
Alleles
There are 6 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa45282 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa40931 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa40930 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa964 | Nonsense | Available for shipment | Available now |
| sa8498 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa45282
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052514 | Essential Splice Site | 8 | 824 | None | 23 |
| ENSDART00000126516 | None | None | 832 | None | 25 |
| ENSDART00000129720 | Essential Splice Site | 8 | 745 | None | 22 |
| ENSDART00000130429 | Essential Splice Site | 8 | 652 | None | 19 |
Genomic Location (Zv9):
Chromosome 7 (position 33165402)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 31559742 |
| GRCz11 | 7 | 31830892 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGTTATTGTTGCATCAGATAGTGGAAAATGGCAAGCGCAGGAGACGCAGG[T/A]AATATTTCTGTATTTACTTATTTAATTTGATTTGCAGTTTTCATTAGTGA
Long Flanking Sequence:
GTAGTAACATATGAAAATACTTCGAGAACTACAGTGTCTATATTACATTACAGTGTTTATATTACCCAATATTAGACTTATTACTCAATTTATTGTAGTCTGCAGTTCTAAAACATCGAAATTGTTTGTTTACATTGAATTTTTAAACATTGTATTGGGCATATTTATTATAAGCGTTAATTTTGAAATACTTAAATTTTCAAAGTTAATAAATGCTATAGCGGTACAGCTTACCTTTTTCTAATTTAACAGAGAAACTTTTATGTTGAAACCACAGACGCTTTAATCTTCCCGGAAGTGTTATTCCGCAATCGAGCAGAAGAACATCGGATCTGTATATGACAACCCACACACAAGAGGGACAGAAATTATCTAGAGATCGGCAAAGGCGCATTGCTTTCCTGCATGTCCTGTGTTTCATTGTGGTTTCCTTTCATTTTTTTCCGGACACGTTATTGTTGCATCAGATAGTGGAAAATGGCAAGCGCAGGAGACGCAGG[T/A]AATATTTCTGTATTTACTTATTTAATTTGATTTGCAGTTTTCATTAGTGACATTGTACTCTAATGAACATTCACGCCTTTCCCTCTGGTTAGGCCTCTTTAAAGAGATTCATTAATGCTGTTTCTATTCAAAACTGCAGCTGTTAACTTACAGGATTTACCCACTGCTTGTTCTGCTGAGCCACTGCTTTAATGTAAACATGTATTGTTATAGGAACCAAAGTCTCTTCTTTTTCTGTGTATAACAGCTCTGTTATTAAAATAGCTCCATTTCTCTCTAAATACAGCTTTGACAAATAAGTCGAGCTGAAAGCAGGTAGCTGAATGACACACAAGGAGTAAAATGTCATATTTAACTTAGGGTATGAATTGACAGGGAACATCCCCTCCCTTCTTTAACTTTCAATTAATTTTTACACTAATTATTGGCATGATAATACTTGTAGGTCTTCAAGTAAAATGAGTGCTGAATAAAGTACAAAATGCTGAAACAGATTTATA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40931
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052514 | Nonsense | 340 | 824 | 10 | 23 |
| ENSDART00000126516 | Nonsense | 348 | 832 | 11 | 25 |
| ENSDART00000129720 | Nonsense | 261 | 745 | 9 | 22 |
| ENSDART00000130429 | Nonsense | 261 | 652 | 9 | 19 |
Genomic Location (Zv9):
Chromosome 7 (position 33150220)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 31544560 |
| GRCz11 | 7 | 31815710 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCAGAATATAAAAGAATGAATTTCTGCTCTTTTTTTTTTTTGTAAGGTA[T/A]GAGTCCAATGGATCTGTATATTTTGACACGGCAAAGTTTGATTCTTGCCC
Long Flanking Sequence:
TGGCAGGGGTTGGGAAAGACATAAGCAGGAGTATGAGGAGCTGGAGCAGGAGAAATTTTCATTTCACTTCATTTTTGGGTGAACTAACCCCTTTTAATGCAGGTGTATATTAATTTCTAGAAAAACAATTACATTTGTAAAAAGTTATTTAAATATTCAGATTTTAGATGTAATAATCAATAAGACTTTTTAAGATTTGTTGCTGAACACAAAACTAATCCTATTTTATGTGCTTTTTAAGTGGCCATCCATGATCATGCAAATTTGTGAAAACATGTTCATTCTAAGCAGTGCTGTTTTTGTTTGGCAGGTCCTTCCTCCTGATGTACTCACACGGGTCAGTGAGTACGTACCAGAGATTGTGGAGTTTGTCAAAAAGATTGTGGACAATGGTTATGGGTAAGAATAAAACTTCTTTCTCCATTGATTGATATATTTCCTTGAGTATTTTGCAGAATATAAAAGAATGAATTTCTGCTCTTTTTTTTTTTTGTAAGGTA[T/A]GAGTCCAATGGATCTGTATATTTTGACACGGCAAAGTTTGATTCTTGCCCTGCTCACTCTTATGCCAAGCTGGTTCCAGAGGCTGTGGGCGATCAGAAAGCTCTTCAGGAGGGAGAAGGTATAGGAATAAATTGCAATATACTCTTTAAAATTGTTTATGCTTTAATTATTTATTTGTAAACATGTCTATCATTATCAACTATTCAATTGTCTATAATATCTATGGAAAACAGATGTGGAATGTCAGTGCAATATTATATATATATAATAAATCTCGATGCACAGCAAAAGAGCACATTGATCAGAAAATGCATAATAAAGATGAGCAGTGAAATCAATGAGCCAGAATTATCCTCTGTATAACACTAAATTAGGAAAGGATGCAGTTGCTTATTTGCTGCCTTTTTATATTCACTAGATTTTTAAATGTTTTTTTATTTTATTATTTTTACCATTTCTTTTCTTGCTTATGCAGGAGACTTGAGCATCTCAGCAGATAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40930
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052514 | Nonsense | 426 | 824 | 12 | 23 |
| ENSDART00000126516 | Nonsense | 434 | 832 | 13 | 25 |
| ENSDART00000129720 | Nonsense | 347 | 745 | 11 | 22 |
| ENSDART00000130429 | Nonsense | 347 | 652 | 11 | 19 |
Genomic Location (Zv9):
Chromosome 7 (position 33147153)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 31541493 |
| GRCz11 | 7 | 31812643 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTATTCTGCTGGTGTTGTTACAGGGGAGACCTGGTTGGCATATTGAGTG[T/A]TCTGCCATGGCCGGATCCATACTAGGAGAATCTATGGATATCCACGGAGG
Long Flanking Sequence:
AACGTAGTCAAGGGTGTAACTTTGATTTGAGAAGTGGGTGGACACAAAATTAGGCAAATGTTTTTGATTTAAATGCCATTTCCTGCATTTACATACATTTAGGGACTATGGTGATACAACATACATGAAATAATTAAGGTTTTTAAACCAACTTTTATTTTAAACTAACCTCAAAATGTAAAAAAAAAAGGTTTTCTAGATTCATGGACATCTGGTGGTCTCTGTGAATATCAGAATCTCTCTGTGTCCTGCTTTGGACATACTCTGCTGTGTTGATGACGGCATGCATCACATAATTTAAAATAATTGATAAAAATTTATTTGAAATGGGTTTTGCATGTCCCCATTGTTACTGAAAATTAGGTCCACCTACTAGGTTTGACAAAGTACACCAAATGCACAAATGTTTTTGAGTGCATTGCCCATGTTTCTAAGTTATGCTGAATGTTTGCTATTCTGCTGGTGTTGTTACAGGGGAGACCTGGTTGGCATATTGAGTG[T/A]TCTGCCATGGCCGGATCCATACTAGGAGAATCTATGGATATCCACGGAGGAGGATTTGACTTACGTTTTCCTCATCATGACAATGAGCTGGCGCAATCTGAGGTGAGAAAACTGCAAGGTGGTCATATGTAAAAATGTTCTGCAGCCATTGTTGAAAAGCCATTATTAGATTTCAGATGATTATTCTACACATTACCCTGCAATCACATCATGTGAGAATTACCATAATTGAAAGTTTCTGGCTTGTTGTAAGGGTCCTTATAAAACTTGAGATTAAACACATATTACTGTTTAATATGCATTTAATTAGAGCCTTTTTCATTTTCGCAAGTGCACAAAGATGTGAAATAATGTAGTGATTACATATTTTGCTGTCATTTAAAGCCAAACTTTGATGCATTTTGTTTCTTTGAGCATTTTTTAAAATGTATTTATTTAAACCTTTATTTCACCAGGAATACCACTTGAGTTTTGGAATCTCTTTCTTAAGAGTGTCCTGG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa964
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052514 | Nonsense | 487 | 824 | 13 | 23 |
| ENSDART00000126516 | Nonsense | 495 | 832 | 14 | 25 |
| ENSDART00000129720 | Nonsense | 408 | 745 | 12 | 22 |
| ENSDART00000130429 | Nonsense | 408 | 652 | 12 | 19 |
Genomic Location (Zv9):
Chromosome 7 (position 33145543)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 31539883 |
| GRCz11 | 7 | 31811033 |
KASP Assay ID:
554-0869.1 (used for ordering genotyping assays)
KASP Sequence:
GATATTTCTTGCACACGGGTCACCTCACCATCGCCGGATGCAAAATGTCC[A/T]AATCTCTGAAGAACTTTATCACCATCAAAGATGCCCWGGCCAAACATACA
Long Flanking Sequence:
CTTAAATAGTAAATCAGAAGACTAAATGTCATGCTGTCATGAGTCTGGTTCTCTCAAGGTTTTTTTTTCTTCACTCTCCTATTGGTGAAGTTTTTTTTCCCTCTCCGCTGTTGCCACTGACTTGCATGGTTCAGGATCTACAGAGCTATGCATCGATAAATTTGCTCTTCAGTGTTTGGACTCTCAGTAATGATTTCAAACCACACTGAACTGAGCTAAACTGAACTGAACTTAAACACTAAAACTGATCTACACTGTTCCAGTTACTATGACCATTTATGTGAAGCTGCTTTGACACAATCTACATTGCAAAAGCGCTATACAAATAAAGCTGAATTGAATTGAATTAAAATAGTTAGGGGATGTGTGTATTCAAGCTTTGTCTTTGTGTCATTAAAACATGTTTGTTTTTGTTCTGATAGGCCTACTTTGAGAATGATTACTGGGTACGATATTTCTTGCACACGGGTCACCTCACCATCGCCGGATGCAAAATGTCC[A/T]AATCTCTGAAGAACTTTATCACCATCAAAGATGCCCTGGCCAAACATACAGGTAACCATGTTATTTTTACAGCATTATTTGAAAGTTACAACATTATATATTGACATCTGCCTATGATTTAGACGAGTTAATTGCACATGATCTCTAAATTTACAATGTATATTTGGCTAGTGCATATTATTATTCTTAAAGTGAACAATTAATCCATGGAAGTTAATCCACTTTTTTTGTTTTGAAATTTATCAAATCTAACAATTTGCATCCACTCTGCAGTGGTAATCTTTTACTGGTGGCTTGGGCAAAACATACATAGCCGCGCCCATTCAAGTATTACTTTGCTGTGAATGAAAGATGAGAGGAGAAGGGCAAAAAATACATAATTGTAACTGCAAAGTATTTTGATGACAAAAATTTCATTGTGACAATGTAACTAATTATGTTGTGACAACCGTCAAGCGTTAAAATAATATTACTTCATGACAATGCCAGACAATCACTTA
Associated Phenotype:
This allele has been associated with this phenotype by genetic linkage analysis and may not be causal.
See FAQs for more info.
See FAQs for more info.
| Stage | Entity | Entity | Quality | Tag |
|---|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
eye ZFA:0000107 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
gut ZFA:0000112 |
quality PATO:0000001 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
head ZFA:0001114 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
inner ear ZFA:0000217 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
larval locomotory behavior GO:0008345 |
absent PATO:0000462 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
lateral larval melanophore stripe ZFA:0005223 |
melanocyte ZFA:0009091 |
present in fewer numbers in organism PATO:0001997 |
abnormal PATO:0000460 |
| Larval:Day 5 ZFS:0000037 |
pericardium ZFA:0000054 |
edematous PATO:0001450 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
skeletal muscle ZFA:0005277 |
degenerate PATO:0000639 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
swim bladder ZFA:0000076 |
aplastic PATO:0001483 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
decreased size PATO:0000587 |
abnormal PATO:0000460 |
|
| Larval:Day 5 ZFS:0000037 |
yolk ZFA:0000084 |
increased size PATO:0000586 |
abnormal PATO:0000460 |
Mutation Details
Allele Name:
sa8498
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000052514 | Essential Splice Site | 571 | 824 | 15 | 23 |
| ENSDART00000126516 | Essential Splice Site | 579 | 832 | 16 | 25 |
| ENSDART00000129720 | Essential Splice Site | 492 | 745 | 14 | 22 |
| ENSDART00000130429 | Essential Splice Site | 492 | 652 | 14 | 19 |
Genomic Location (Zv9):
Chromosome 7 (position 33141499)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 7 | 31535839 |
| GRCz11 | 7 | 31806989 |
KASP Assay ID:
2259-9038.1 (used for ordering genotyping assays)
KASP Sequence:
CTGGCCAATATGAGAAATGGGAAGCTGAGGAGATTGAACTGAACAAATGG[T/G]AACTTGTATGATTCTTACATGATTGTCATTTTTCAAAAGTTAAATTTCTA
Long Flanking Sequence:
ACCGCCCCTTTTAGGCTTTAATTCTAATTGTGTCATTCTTCTCACAGTCCTCTTTTCAAAAGAGGGCGGAGCTACAAATCCCTGTGTGTTAACGAAGTGGCAGCTTCAAAATTAATACTAACATCCTATACTAATGAGGATGAGCGGCAGAGATCATCACTAATGGGCGGGCTTTTCCCTTCTGATGACATGTACAAAAAAAAACATGTCAATCAAAGTGGTTCTGCTGATTTGTGTGATTATAAAAATAAAATTAATAATGTTTTACCATCAGAAGCTGGTTGTATTCACACATTGTTGCCACACAACTGTGATTACACCTCTTATCAAAGTGATTTTTAAATAATAGGTCATCTTTAATGCACATAATATTATATAGCTCATATTTCATGTCTCCACAGGAGTTCTTCCTAAATGTTAAAGATATTCTGAGGAGCCCTACAGACATCACTGGCCAATATGAGAAATGGGAAGCTGAGGAGATTGAACTGAACAAATGG[T/G]AACTTGTATGATTCTTACATGATTGTCATTTTTCAAAAGTTAAATTTCTATCACTCATTACATGTGTGTATTTATTTAGCTTCTATGACAAGAAAACATCAGTTCATGGGGCGCTGTGTGATAACATAGACACTCGTTCAGCTCTGGAGGAGATGCGGGCTCTTGTTGGTCAAAGCAACACCTACATGGCTGCCAGGAGGAGTGCAAAACTACCACCAAACCGCATGCTGCTACAGAGCATCGCCCTGTACTTGACTGACATGTTGAAGGTAACAAGTCAGCTTCACTTCTGACCAACATTTTCAGAAAAAAAATTTCAGGATGTGGTATACTTGTTGGTTTTTTACAGTTCTTCAATTGGGGGTAAAGAGAAAAGTTAGCATTTTTTCATTCGTAGTTCTATATAGTTAGCAAACATTTCAAAAAATGAGTATCTAAATGCAGATGAAATCATTAGTCCTTCTGTGAAATTTTCATTCATTAAAAAAAAAATTCTTCTT
Associated Phenotype:
Not determined