Busch Lab

ZMP

riok2

Ensembl ID:
ENSDARG00000035264
ZFIN ID:
ZDB-GENE-040426-2913
Description:
serine/threonine-protein kinase RIO2 [Source:RefSeq peptide;Acc:NP_998719]
Human Orthologue:
RIOK2
Human Description:
RIO kinase 2 (yeast) [Source:HGNC Symbol;Acc:18999]
Mouse Orthologue:
Riok2
Mouse Description:
RIO kinase 2 (yeast) Gene [Source:MGI Symbol;Acc:MGI:1914295]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa31468 Nonsense Available for shipment Available now
sa13574 Nonsense Available for shipment Available now
sa1588 Essential Splice Site F2 line generated Not yet available
sa33677 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa31468
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051092 Nonsense 14 512 1 10

The following transcripts of ENSDARG00000035264 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 43263509)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 41044774
GRCz11 5 41644927
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTGTGCCACTATGGGCAAATTAAACGTGGTAATCCTGAGGTATCTGTCT[A/T]GAGATGATTTTAGAGTGCTGACAGCGGTACGTATCCATTTCATAAAACCG
Long Flanking Sequence:
GGCAAAACCCCATTAGACTTGACCGTTATAAGAACTGTTAAGTTAAAATAACTTTTACTTTGTAGATAATATAAATGAATTAAAAAAAATTAAAAACATTAAAAAAAGTTTTAAAAACTTTACATGCCTTGGCTGTTTTATTCTCTTACATTGTGTTACTTTATTGGCATATTCTGTGTATGTGTGTGCTCTCATTTGCCCTGGTCTCATGTTTGTACTTGATTTTTAAATGTTGGTAATGTGCCTGTTTTTTTGCAAGTGTGTGGGAAAGGTGTCGCGTGCGCTTCCGCTCCGGGCCGCCAGGAGAATCGCTGAGTTTGTCGGCTTCACTGATGCAGACGTCAGAATTCTGCACTCTTCCGGTTGAAACATGTGGAAGGGCTGGAAATAATATCGCCTTGTGAAAAAATTGGCAAAAAGGAGAAAACTTTTGAAATTTAGGAAACACCGACTGTGCCACTATGGGCAAATTAAACGTGGTAATCCTGAGGTATCTGTCT[A/T]GAGATGATTTTAGAGTGCTGACAGCGGTACGTATCCATTTCATAAAACCGTCTATTTGTTTACTAGACTTTTCATCCAGCTTTAATGTAACAACATTTCGACTAGCTCACAGTCTTTATAGAACATAAGCAATATTAACATTAAACTGCCAACCGAGTGACAGTTTTATCAGTGCAGTTTCGTTGTTCTTGTTAAATCATTGTTAATTATACTGTAATAATTGTGTATACATACGTTTCATACTATAAATGTTTACGTTATATATAAAATGTCTTTTTACTTAAGTTAAAACATTAGAATTTTGTCTCAAATTTGGTATAAATGTCTGACAACATTGTACTGTTTTGTGCGTTTGTCTTTGTATGTATATGTATACAGTGTATATACACAATGAGGTTAAGTTGATTTTATATTCGCACATTCAGACTTTTTTCTTAATAATATTATTTCAGAAAAATATTCATTGCTTATTCTAAATAGTGAAATCATATTAGCAGCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13574
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051092 Nonsense 135 512 4 10

The following transcripts of ENSDARG00000035264 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 43261724)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 41042989
GRCz11 5 41643142
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCAGTTTGCTCTGAAACTTCATAGACTGGGCAGGACGTCCTTCAGAAACT[T/A]GAAGAATAAGAGAGATTATCACAAGCACAGAAACAATATGTCATGGYTGT
Long Flanking Sequence:
AAGTCTAATTGCGTCCATTGCCAGCCTCAAACACGGAGGATGCAACAAGGTTTTGCGAGAGCTGGTCAAACACAAACTTCTGGCCTATGAGCGCAGCAAAAGTAAATGCTTCAGCATTGATAATATCATTCAGTAGTGTGTGGGGGTCTTTGCAGATTCTGACTGTTTCCTCTCTAGCTGTACAGGGCTACCGGCTGAATTACGGTGGATATGATTACCTGGCGCTGAAGACACTTTCATCCAGAGATGTGATTTTATCAGTTGGAAACCAGATGGGAGTTGGCAAAGAGTCAGGTCAGGACATTTTTTTTATAAAGATGAAGGATACATATTTACATGTTTTTTTTTTTTTTGTTTTTTTTTTTAAACAAAAAGGATACTTTCTTCATACTTAAAACACACTTTTTTAATTTTTATAGATATTTACATTGTTGCTAATGCGGAGGAGCAGCAGTTTGCTCTGAAACTTCATAGACTGGGCAGGACGTCCTTCAGAAACT[T/A]GAAGAATAAGAGAGATTATCACAAGCACAGAAACAATATGTCATGGTTGTATCTGTCTCGGCTCTCTGCCATGAAAGAGTTTGCATACATGAAGGTAAAACCCCAAAAGCTGAGTTGTTGTTGTTGTTTAGGCCAGGGGTGCTCAACCCTGTTCCTGGAGATCTACCTTCCTATAGAGTTTAGCTCCAACCCCGATCAAACACACCTGAGCCAATTAATTAGGACATGAACAGCACTTGATAATTACAAACAGGTGTGTTTGATCGGGGTTGCAACTGAAATCTGCAGGAAGGTAGATCTCCAGGAACAGGGTTGAGCACCCCTGGTTTAGGCTGTTCGTCAGGATTTATTTTATGATTCCTTTTTTTTTTTTTTTTTAAACAGGCTTTATATGATCGAGGATTTCCTGTTCCAAAGCCAGTGGACTACAACAGACACGCAGTGGTGATGGAGCTCATTAACGGTTACCCGCTGTGAGTTTACATGCACTTTAAGATCAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1588
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051092 Essential Splice Site 260 512 6 10

The following transcripts of ENSDARG00000035264 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 43260887)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 41042152
GRCz11 5 41642305
KASP Assay ID:
554-1530.1 (used for ordering genotyping assays)
KASP Sequence:
TGATCGACTTCCCTCAGATGGTCTCCACCTCACATATAAATGCAGAATGG[T/C]GAATATCTGTTCAGATATCAAACTGATTATTATTATTTAATAAAGAACAA
Long Flanking Sequence:
TCGTCAGGATTTATTTTATGATTCCTTTTTTTTTTTTTTTTTAAACAGGCTTTATATGATCGAGGATTTCCTGTTCCAAAGCCAGTGGACTACAACAGACACGCAGTGGTGATGGAGCTCATTAACGGTTACCCGCTGTGAGTTTACATGCACTTTAAGATCAACATATTTTACGCAATATAGACTTTTGTTACAATAAAAACTTTAATGCATGATGATTAATAATCTGTCATTTAATCAGAAATATTTTGATCCATTATTCATGATTTTGTAATAGTAATGGAATATTGCTGTATTCTCTGCACAGGTGTCAGGTTCGAGAGATTCAAGATCCTGCTGCACTGTACAGCGAAATCATGGAGCTAATAGTCAAACTGGCCAATCATGGCCTGATCCACGGAGACTTCAATGAATTTAACCTAATGCTTGACGACAATGATCACGTCACAATGATCGACTTCCCTCAGATGGTCTCCACCTCACATATAAATGCAGAATGG[T/C]GAATATCTGTTCAGATATCAAACTGATTATTATTATTTAATAAAGAACAATTGCAGCAATGTAATAAATGTTCTGTTTCCTGAAAGGTACTTTGATCGTGATGTCAAGTGTATTCGAGATTTCTTCATAAAAAGATTTAACTATGAAAGCGAACTCTATCCAACCTTCAAAGATATCAGGTAATGTTTTTTTCTTTCAGAATGCTTTACTATGATGTTGTCCTAACTTCAGAGGCTGAACAAAGTCACATTTTCCTCTATACAGAAGGGCATGTTCACTGGATGTGGAGATCTCAGCTAGTGGCTACACAAAAGAGCTGCAGCAGGACGACAGTTTGCTCCACCCTGAAGGTCCTGAGAGTGATGGAGATGAAGACGATGAGAGCCCAGAGTCAACTGACGACACGCATCAGGCGTCTGCAGGGGACACTATCGACATGGAGGAGTTTAAACATGCCATGCTTGAGCTACAAGGGCTAAAAATAAGTGCAGAGACTTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33677
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000051092 Nonsense 284 512 7 10

The following transcripts of ENSDARG00000035264 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 43260728)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 41041993
GRCz11 5 41642146
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTATTCGAGATTTCTTCATAAAAAGATTTAACTATGAAAGCGAACTCTA[T/A]CCAACCTTCAAAGATATCAGGTAATGTTTTTTTCTTTCAGAATGCTTTAC
Long Flanking Sequence:
ATCAACATATTTTACGCAATATAGACTTTTGTTACAATAAAAACTTTAATGCATGATGATTAATAATCTGTCATTTAATCAGAAATATTTTGATCCATTATTCATGATTTTGTAATAGTAATGGAATATTGCTGTATTCTCTGCACAGGTGTCAGGTTCGAGAGATTCAAGATCCTGCTGCACTGTACAGCGAAATCATGGAGCTAATAGTCAAACTGGCCAATCATGGCCTGATCCACGGAGACTTCAATGAATTTAACCTAATGCTTGACGACAATGATCACGTCACAATGATCGACTTCCCTCAGATGGTCTCCACCTCACATATAAATGCAGAATGGTGAATATCTGTTCAGATATCAAACTGATTATTATTATTTAATAAAGAACAATTGCAGCAATGTAATAAATGTTCTGTTTCCTGAAAGGTACTTTGATCGTGATGTCAAGTGTATTCGAGATTTCTTCATAAAAAGATTTAACTATGAAAGCGAACTCTA[T/A]CCAACCTTCAAAGATATCAGGTAATGTTTTTTTCTTTCAGAATGCTTTACTATGATGTTGTCCTAACTTCAGAGGCTGAACAAAGTCACATTTTCCTCTATACAGAAGGGCATGTTCACTGGATGTGGAGATCTCAGCTAGTGGCTACACAAAAGAGCTGCAGCAGGACGACAGTTTGCTCCACCCTGAAGGTCCTGAGAGTGATGGAGATGAAGACGATGAGAGCCCAGAGTCAACTGACGACACGCATCAGGCGTCTGCAGGGGACACTATCGACATGGAGGAGTTTAAACATGCCATGCTTGAGCTACAAGGGCTAAAAATAAGTGCAGAGACTTTATCAGAAGAGAACAACACAGAGCCTGAGGGAGCACGATGTGAGCAGGACGTCCCCTCAGAGGATCTTCAGACAGAAATGGTTTCTGGCATTTCTGAAGACTTGGGCAGAGATGAGGTGGAGGATGAGTGTCCTGATTTGGTTGACCTGTCTGCATGCAATA
Associated Phenotype:
Not determined