Busch Lab

ZMP

lrwd1

Ensembl ID:
ENSDARG00000035147
ZFIN ID:
ZDB-GENE-030131-5335
Description:
Novel protein (Wu:ft31b04) [Source:UniProtKB/TrEMBL;Acc:B0R160]
Human Orthologue:
LRWD1
Human Description:
leucine-rich repeats and WD repeat domain containing 1 [Source:HGNC Symbol;Acc:21769]
Mouse Orthologue:
Lrwd1
Mouse Description:
leucine-rich repeats and WD repeat domain containing 1 Gene [Source:MGI Symbol;Acc:MGI:1918985]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa14204 Nonsense Available for shipment Available now
sa16789 Nonsense Available for shipment Available now
sa26601 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa33743 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14204
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000050906 Nonsense 152 763 4 15

The following transcripts of ENSDARG00000035147 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 64550123)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 60802783
GRCz11 5 61487504
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTSTAAANNGTGTTTTCTTGACYGCCTTTAGGTGATTGGTGTGTGGGAA[C/T]GAGACTTTAGTCTTCCTGATCCCATTTCAGCAWAAAGCCTTGCTGCTGTT
Long Flanking Sequence:
TGCTTACACACAACACATTAAATAAAATACACATATACTCACAATTGAGCGATAACTTTAAATGTTCTCAACTATTGAACTAAATGTGAAGGCCGGTAGCGAAAGTGATCCATGTGGTGGTCACTCTACCAAACACTCCTTCTTACTCTATGGTAAGTGACTTTTTATACAGATGCGAATCAACCTAGTGCCCCTGGAGGTCGGAAGCAGTATTACATGTCCACATACCAAACAAAACACAATGCAAGAAAATAAATAAATCAGAAAATAATACTAGTAACATTTAACATGTTACATAGTTTTAGCACTGAAGTCAATACTTTTGACAACTCTACTGTCTACTAACTGTACTACTACTACTGTAACTTTACTATGTAATAATCCTGCCGGAAATTTTGTTACATTTCTTATTACTTGCATATTTTTTAAAACCCTTTAAAAGTGATCCTATTTGTAAAGTGTGTTTTCTTGACTGCCTTTAGGTGATTGGTGTGTGGGAA[C/T]GAGACTTTAGTCTTCCTGATCCCATTTCAGCAAAAAGCCTTGCTGCTGTTGAGAAGAGCTTTGTTAACGCTGCCTGCACACAAGTCAAGTATGGCCCCAATTCCTTGAGTGATTACACAAAGTGGAGGGTCAGTATTATGTGAATGTTGTGTTCCTGAGACAGATTTTAAGTTTATAGGTCAGTGTTTCTCAACCACGTTCCTGGAGTACCTCCAACACTGCATGTTTTGGATGTCTCTTTTGTCACACCCATTACAGGTCTTTCAGTCTCTGCTTATGAGCTGATGATCTGATTCAGGTGTGTTTAATTAAGGAGGCAAGAAGAATGTGCAGAGCTGGTGGTCCTCCAGGAAAGTGGTTGAGATATATTGTTTTAGAGCATCTAAACTGTTGTGGTTTCAGCAGATTTTAACTTTTCAACTCATCCTGTTTCTGCTTATTCAGGTTGAAAAGATTGCAAAGGAGTATTTGAAGTCACTGACCAGTAGTGAGGAGGAAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16789
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000050906 Nonsense 163 763 4 15

The following transcripts of ENSDARG00000035147 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 64550156)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 60802816
GRCz11 5 61487537
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGATTGGTGTGTGGGAAYGAGACTTTAGTCTTCCTGATCCCWTTTCAGCA[A/T]AAAGCCTTGCTGCTGTTGAGAAGAGCTTTGTTAACGCTGCCTGCACACAA
Long Flanking Sequence:
TATACTCACAATTGAGCGATAACTTTAAATGTTCTCAACTATTGAACTAAATGTGAAGGCCGGTAGCGAAAGTGATCCATGTGGTGGTCACTCTACCAAACACTCCTTCTTACTCTATGGTAAGTGACTTTTTATACAGATGCGAATCAACCTAGTGCCCCTGGAGGTCGGAAGCAGTATTACATGTCCACATACCAAACAAAACACAATGCAAGAAAATAAATAAATCAGAAAATAATACTAGTAACATTTAACATGTTACATAGTTTTAGCACTGAAGTCAATACTTTTGACAACTCTACTGTCTACTAACTGTACTACTACTACTGTAACTTTACTATGTAATAATCCTGCCGGAAATTTTGTTACATTTCTTATTACTTGCATATTTTTTAAAACCCTTTAAAAGTGATCCTATTTGTAAAGTGTGTTTTCTTGACTGCCTTTAGGTGATTGGTGTGTGGGAACGAGACTTTAGTCTTCCTGATCCCATTTCAGCA[A/T]AAAGCCTTGCTGCTGTTGAGAAGAGCTTTGTTAACGCTGCCTGCACACAAGTCAAGTATGGCCCCAATTCCTTGAGTGATTACACAAAGTGGAGGGTCAGTATTATGTGAATGTTGTGTTCCTGAGACAGATTTTAAGTTTATAGGTCAGTGTTTCTCAACCACGTTCCTGGAGTACCTCCAACACTGCATGTTTTGGATGTCTCTTTTGTCACACCCATTACAGGTCTTTCAGTCTCTGCTTATGAGCTGATGATCTGATTCAGGTGTGTTTAATTAAGGAGGCAAGAAGAATGTGCAGAGCTGGTGGTCCTCCAGGAAAGTGGTTGAGATATATTGTTTTAGAGCATCTAAACTGTTGTGGTTTCAGCAGATTTTAACTTTTCAACTCATCCTGTTTCTGCTTATTCAGGTTGAAAAGATTGCAAAGGAGTATTTGAAGTCACTGACCAGTAGTGAGGAGGAAGAACGGGTTGCAGACACAACTCCAACAAAGGAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa26601
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000050906 Essential Splice Site 194 763 4 15

The following transcripts of ENSDARG00000035147 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 64550253)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 60802913
GRCz11 5 61487634
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAAGTCAAGTATGGCCCCAATTCCTTGAGTGATTACACAAAGTGGAGGG[T/C]CAGTATTATGTGAATGTTGTGTTCCTGAGACAGATTTTAAGTTTATAGGT
Long Flanking Sequence:
AAACACTCCTTCTTACTCTATGGTAAGTGACTTTTTATACAGATGCGAATCAACCTAGTGCCCCTGGAGGTCGGAAGCAGTATTACATGTCCACATACCAAACAAAACACAATGCAAGAAAATAAATAAATCAGAAAATAATACTAGTAACATTTAACATGTTACATAGTTTTAGCACTGAAGTCAATACTTTTGACAACTCTACTGTCTACTAACTGTACTACTACTACTGTAACTTTACTATGTAATAATCCTGCCGGAAATTTTGTTACATTTCTTATTACTTGCATATTTTTTAAAACCCTTTAAAAGTGATCCTATTTGTAAAGTGTGTTTTCTTGACTGCCTTTAGGTGATTGGTGTGTGGGAACGAGACTTTAGTCTTCCTGATCCCATTTCAGCAAAAAGCCTTGCTGCTGTTGAGAAGAGCTTTGTTAACGCTGCCTGCACACAAGTCAAGTATGGCCCCAATTCCTTGAGTGATTACACAAAGTGGAGGG[T/C]CAGTATTATGTGAATGTTGTGTTCCTGAGACAGATTTTAAGTTTATAGGTCAGTGTTTCTCAACCACGTTCCTGGAGTACCTCCAACACTGCATGTTTTGGATGTCTCTTTTGTCACACCCATTACAGGTCTTTCAGTCTCTGCTTATGAGCTGATGATCTGATTCAGGTGTGTTTAATTAAGGAGGCAAGAAGAATGTGCAGAGCTGGTGGTCCTCCAGGAAAGTGGTTGAGATATATTGTTTTAGAGCATCTAAACTGTTGTGGTTTCAGCAGATTTTAACTTTTCAACTCATCCTGTTTCTGCTTATTCAGGTTGAAAAGATTGCAAAGGAGTATTTGAAGTCACTGACCAGTAGTGAGGAGGAAGAACGGGTTGCAGACACAACTCCAACAAAGGAGAATAAGGTAAAGCCATACGAATACCATTTTTTTCAATGTTAACATTGTAAATCCTCAAATTATTTAAAAAATAATAAAATCTAATTTACGTTTGAAAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33743
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000050906 Essential Splice Site 543 763 10 15

The following transcripts of ENSDARG00000035147 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 64561417)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 60814077
GRCz11 5 61498798
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTGTGGGACATTGGTGGACTGGATCAGGATTACAACTTTAAAATCAGG[T/C]ATTATTATTGAATTTTCAGTAAACAGTGGGAGAAATAAGTATTCAACACG
Long Flanking Sequence:
AGAACATGCAAACTCCACACAGGAATGTCAACTGGCTCAGTCGGGACTCAAACCAGCGACCTTCTTGTTGTGAGTGCCCGACTGTCATCCAGTACCTGTAAATTTAGGTTTGTGTCTGCTGTTGTCTTGCAGGATTTTTTCTCTTTAGCCTGGTCCACTGTGCTGATGTCCAGAACAGGTGGCTCTGCCCGTCCCTGCAATATCCTGGCTGCTGGAGGAAAGAGAGGTTGTGTGAAGCTCATCCATCCCCGAGTCAACCTGGCATTTGGAGAGTTTCGCGTCAGTCGACGTGCCATTTCCATAATGCGCTTCAATCCACGCAAACCCACCTTTCTCTTCAGTGAGTGAAACAGATTTTACATAGACTGAAAGATGGTACATTTAAGCTATATAGACAACTAAAAGTCACTTTATTTCTATTTGTAGCTGGGACGTATGATAAAAAGATCTTTTTGTGGGACATTGGTGGACTGGATCAGGATTACAACTTTAAAATCAGG[T/C]ATTATTATTGAATTTTCAGTAAACAGTGGGAGAAATAAGTATTCAACACGTCACCATTTTTCTCAGAAAACATATAGGTGCCGTTGACTTGAAATTTTTGCCAGATGTTGATAGCAACCAAAGAAATCCATAAATGCAAAGAAAATAATATTAATTAGCTTACAAATGAAGTTAAGTGTATTAAAATGAAATGACTCAGGGAAAAAGTATTGAACACATGAAGAAAGGAAGGTGTAGAAAGGCAGTGAAAGCCCAGACAGCAGCTGAAATCTCTCAGTAGTTCTTCAGCAACCCTGTAACCCTTCCTCATTGTAAATGAATATCAGCTGCTTCAGTCCAACATCTACATTAGAAGGATGATGAAGATGAAACCGGAGTGGACGTTTCAGCAAGACAATGATCCAAAACACAGCCAATGAAATTCTCTCATGGTTTCAGGGAAAGAAGACAAAGCTGTAAAATGGCCCAGCCAATCACTTGATTAAATCCAATAGGAAATA
Associated Phenotype:
Not determined