Busch Lab

ZMP

grin2aa

Ensembl ID:
ENSDARG00000034493
ZFIN ID:
ZDB-GENE-070424-129
Description:
Novel protein similar to vertebrate glutamate receptor, ionotropic, N-methyl D-aspartate 2A (GRIN2A)
Human Orthologue:
GRIN2A
Human Description:
glutamate receptor, ionotropic, N-methyl D-aspartate 2A [Source:HGNC Symbol;Acc:4585]
Mouse Orthologue:
Grin2a
Mouse Description:
glutamate receptor, ionotropic, NMDA2A (epsilon 1) Gene [Source:MGI Symbol;Acc:MGI:95820]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa13836 Nonsense Available for shipment Available now
sa14573 Nonsense Available for shipment Available now
sa40072 Nonsense Mutation detected in F1 DNA Not yet available
sa40073 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa13836
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073979 Nonsense 58 1460 1 12
ENSDART00000142141 None None 1325 None 11
Genomic Location (Zv9):
Chromosome 3 (position 27225743)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 26943782
GRCz11 3 27074624
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGGTCARACTCGCTACATCTCTGACAGAGATATACGGGCTCTGTGGAGC[A/T]AAGATGATCCTATTGATGTCAATGTGGTGACCCTGCTGGTGAATGAAACA
Long Flanking Sequence:
ACATGTAATATTCATCATTTGCTCATTGCTAGTTATTCATTGCTTAAATTCCAAAATGAGATTTAAAAAAATCTCGTGCTCCTTACCATTGTTGTGTAACTCCACTGGATGCTGTTGAAAACGTATGAAGTTGTTAAATCAGTATGCAGCAAGGAGCATTCAGCAATGTTGCATAAGCTTTAGATGTCTGAAGTCATTTCATGTCTCCTCTTTGAGAAAAAACTATAAATGTATTATATCTGTGAATTATATATATGTATTATATGATTATAAATGCAGTATATCTCAAACGGCCTCTGTCGTGTGTGTGTGCATTTGTTTCGCAGGGAATGAAGTCGAGCACTATGGGGTTTTCCAGGTTGGTTCTTCTGACTCTTCCAGCTCTCCTTACCCTCATCAGCATCTCACATGCGGCAGAGAAAGTGCCCATACTGAACATTGCTGTGATCCTGGGTCAGACTCGCTACATCTCTGACAGAGATATACGGGCTCTGTGGAGC[A/T]AAGATGATCCTATTGATGTCAATGTGGTGACCCTGCTGGTGAATGAAACAGACCCCAAAAGCATCATTACCCATGTGTGTGACCTCATGTCCGGGACTAAAATCCACGGGGTGGTGTTCGGGGACGGCACAGACCAGGAAGCCATTGCCCAGATTTTGGATTTTATTTCCTCTCAGACTTTGATACCCATCCTTGGGATCCATGGTGGCTCATCCATGATCATGGCGGATAAGGTCAGTAGTATGCCAAGCATCAGCTCAACTGCTCAAAAAGATGAGCGGGAAATATTATTCACAAAATGAGTTCTGCTGGTAAAAGTATGCGCCCTTAATGTGGTTTGGTAATGACAATGATGTAAAATAATGTTATTAGTGCAACATGCAATAGTGCCTTAACTGTTCCCGTGACAAATTACCATATGGAGTTATTTCACAACATATGCTCCGTCAAAAAAGCTGAAGTAATCACTTTACTGAACCCGATAACAAATATCTCTTTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14573
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073979 Nonsense 345 1460 3 12
ENSDART00000142141 Nonsense 210 1325 2 11
Genomic Location (Zv9):
Chromosome 3 (position 27358238)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 27076277
GRCz11 3 27207119
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTCTGCTTCCTGTAGGTACATGATGAACGTGACCTGGGATGGCAAGGATT[T/A]GTYCTTCACCGAGGACGGTTACCAGGTGCWTCCMAAACTAGTGGTGATCG
Long Flanking Sequence:
TGGACTTGCGGTAATGTAATAAAACAAGATTGTATTTTAATAAAAAAAACCTTACACTGTAATGTGTTAATCTCCATAATGCCATCCAGAATGAACTCCTAATGTTTCCTTAGAATGGATTTCTTTCATTTTTATGACTATACGCACTTTCTTTGAAGATGAGCACAAAAGAAAGAACAGTTGTGATTCATGTAGATTTCACTGGATACTAATAATAACTCGGGCAGATTTTTCATGTTTCGCTTAATGTGACGTCTGATTTAGGTCAGTCATTAGTCTTCAGATGGCTCATTAATTCCTCTTTTTGTCTTCTCGCATGTTGAAAATGACCTTCATATGTTATTTTGATCTTTTAGGTATAGAATGAACATCATTAGGACGATAAGTTCTCTTTGTGCAGCAGATAAGATTCGTGTCACCTGACTGCTCTATTTCTGGCCCTGATGAGCTCTCTGCTTCCTGTAGGTACATGATGAACGTGACCTGGGATGGCAAGGATT[T/A]GTCCTTCACCGAGGACGGTTACCAGGTGCATCCCAAACTAGTGGTGATCGTGCTGAACAAGGACAGAGAGTGGGAAAAGGTAAGGCAGCCGAAAACAACTGACCCTCTTAACCACGTCATTATAATTTCATTATAACTCCTCCAAGCAAAGCGTCATTAACAACTGTTCACACAATATTAGTACTCATGAATCCACCATATTAATTACACCCTGGAACGGTGTAAAAGTGTGTCAGTGCGGTAATTACCTCAGACGCACACAGCCAGAGTCTGCAAATTCGGTGGTGTAATTAGGACCTGTTTTTTCCCTTTCTTCCTTTTAGACCGCAGTCAAGGCAGACGGGAATACACACGTGTGTATTAGTGCAGATAGCTTGGATGAGTGAATCTCTCTTTTTTCTGTTGTAGGAGAGAATGCAGTTCAATAAAACTAGAGCGGGAGGAATAATTGGAACAGCAAAACAATGGGGGAAATTGATTTGTGAAGTTCGCTGTGGAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40072
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073979 Nonsense 384 1460 4 12
ENSDART00000142141 Nonsense 249 1325 3 11
Genomic Location (Zv9):
Chromosome 3 (position 27394604)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 27112643
GRCz11 3 27243485
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTCTTTTTCAGATGGGCAAATGGGAGAACCAGAGTTTGACTTTGAAGTA[T/A]CCGGTGTGGCCCCGTTTCAACTCTTTCGGGGATGCGGAGACAGATGACAA
Long Flanking Sequence:
TGAAGATAAATACCCAAAAATAATGAAACTGGAATAACTACAGCAGTTACCATTGTCAATCTCTTTTGAAATAAGAGCTTGCGATGACATATGATGATGTGTGCAGGTATTGTTGTCCTGTTCCATTTCGTAGGGGTTAATTTGAAGCCCTTCAGCTTCACACTCTGGGGCCAAGGGGTAGGGGTACGAAAATAGTGTTGGGATTGGGCCTATATACTGCCACTATGTCGTTATATACACTATTTACAATATACTGCATGCTTGTATCAACCCAGACCTGTACATTTCTACAATATGGAAATTACTTTGACGCAGCAACCTCTGATGACAATATTACTAGAAGCAGGCTTTCTTTCTATAGAGCTGCTTTGAAATACTGTATATCATACAAAGTGATACTCAAATAAACTTGAATCGAATTGAACTGAAAGAAGTTATTCATTTTTTAAAATTCTTTTTCAGATGGGCAAATGGGAGAACCAGAGTTTGACTTTGAAGTA[T/A]CCGGTGTGGCCCCGTTTCAACTCTTTCGGGGATGCGGAGACAGATGACAATCACCTGACCATTGTAACGCTGGAGGAGAAGCCTTTCGTCATTGTGGAGAATGTGGAGCGCCTCACAGGCACCTGCATGAGGAACTCTGTACCCTGCCGCAAACACATCAAAGAGTAAGCCTTGTTTTTCTCATCTTCCCCATCACTCATATGTCACCTCAAAGTACCACTCTCAAACTGTTGGATGCTTGCCGTTTTGGCCCTAGAGAGCTGCATAGAGTGATGTAAGAGCGCTCTTGAAGAGAGTTTGATATATATTGAGGGTTGTTGATGACTACATGACTACATATATCAATCAGTACGGTAGCGTGTTACTGTCTGTTTGTGACTGGAAGACATCAAAGATTTTTACATCCTGGTTATAAATAGCACCTTGACCTTGACTTATTGTTTAAGAGAGACCTGCAGGCATTGTTCTTGAACTTTAAATGTTTCAGAAGAAAGAAGCCT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa8122
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073979 Nonsense 734 1460 10 12
ENSDART00000142141 Nonsense 599 1325 9 11
Genomic Location (Zv9):
Chromosome 3 (position 27419016)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 27137055
GRCz11 3 27267897
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCCCCAGCAAACTTGAWGCCTTCATTTATGATGCTGCTGTGCTRAACTA[T/A]ATGGCTGGTAGAGACGAGGGTTGTAAATTGGTGACCATTGGAAGTGGCTA
Long Flanking Sequence:
ACTGTACAAAGAATTCAAAAGCGCCAGTAAGTTAGAAGCAACAATAGCAAGATGGAAGATGCAGGCTTACACAAACAAACAATTCTGTAAAGTATTCTGCCTTGTTTTTTCTTTCTTTCTTCTTCTTACTGATGAAATGCATTTTGCAAATTTCCTGCTCCCTTTTGCAGACACCAGTTTGACAACCCCAGCATAAAAAAATCAGGCCAAAGTCAATCAAATCGCTTTCTCTGCAGTATATTTTTCTCCACTTCTTGTGGTGTGATTGCACCCAGTGTTGTCTCTCACTTTAAACTTGTGATTTCGTGACTACGTCATTGCTGTGAAGTTAAAATGAGTTATGATTCATTCAGTGCTTTTGGTAGCATGACATTGGTGTTAATGAATGAGAATGACTCAGAACACTGAACATTTAACCTCTCTATTTGCCATTTGTCTGTGCTCTTTTCTATCCCCAGCAAACTTGATGCCTTCATTTATGATGCTGCTGTGCTGAACTA[T/A]ATGGCTGGTAGAGACGAGGGTTGTAAATTGGTGACCATTGGAAGTGGCTACATCTTTGCTACCACTGGTTATGGCATTGCCCTCCAAAAGGGGTCACTCTGGAAGCGTCCGGTGGATCTGGCTATTCTCGCTATTATTGGAGATGGTAAGTGCCTTCAGAATCATATGCATGTTAGAATGCACTATAAGGATTTCAATTCTTTTAAAATATGTATATTTAAATAAAGCCTAGATGATTTGCATTTGAGTGCTAACAATATTATTTATACTATTTAATTGAACATATCAAATAATATTAAAAATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACTACACACACACACACAGGGCTTGACATACACTTCCATGAACACCAGCCACTGTGGCTAGTAGTTTTCCAACGTTACTAGCCACTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40073
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000073979 Essential Splice Site 783 1460 11 12
ENSDART00000142141 Essential Splice Site 648 1325 10 11
Genomic Location (Zv9):
Chromosome 3 (position 27421196)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 27139235
GRCz11 3 27270077
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTGGAGAAAGCTGATTGATGACGTGGATCTGGGCATGTGCATCTCTCTTC[A/C]GGTGAGATGGAGGAGTTGGAGGCTCAGTGGCTGACTGGAATCTGCCACAA
Long Flanking Sequence:
GTATGTTGAAAGTATATAAATTCCTCATTTATAAGTCTCTTTGGATAAAAGTCTCTGGTAAATGAATACATTTCAATATCAATATCTGCTTCAAACAAATATAAAAAAAAATCATGCAGTGTTGTAAACCCAGAAGTAGAATGCCCATCTGTTACATTATTTAGCTTTCTTTTAACATGCATTTCTGCATTGTTTCCCTCTCTATACACTATAAGCTATGTTTCACAGTAATGCTGTACGCAGAGCATGAAAAATGACAGAATTATCCTCCTGGCAGCTGCACCTTGTAGAGAAAGAGAAAAAAGTCTCAGATGGTACTAACATATGGCTGAAGCTTGAGTGTATAATTTTACTGATCCTCAGTTTGACATGCTAGCACATAGGGAGTTCTGGAACAGGAGGATTCGTCTGTGGACGGTAGCGGTGTGGCCCACTGAGGTGTACATGAATTTGGAGAAAGCTGATTGATGACGTGGATCTGGGCATGTGCATCTCTCTTC[A/C]GGTGAGATGGAGGAGTTGGAGGCTCAGTGGCTGACTGGAATCTGCCACAATGAGAAGAACGAGGTAATGAGCAGCCAGCTGGATGTGGACAACATGGCTGGAGTGTTCTACATGCTGGCGACTGCCATGGGTCTCAGCCTCATTACCTTTGTCTGGGAGCACCTGTTCTACTGGAGACTCAGATACTGCTTCACAGGCGTCTGCTCAGGCACGCCCGGCCTGCTCTTCTCCATCAGCAGGGTAAGGCTCTCATTCAGTCTGTTTGCTCAATAAGTTGTGAAAATGTGAAGTCAGCAAAAACAAGTGCTAACATGGCAACACTCATAGTTGACATCTGTCTGTGCTGTGGGACTTGGTCTATACCTGTACAGAACATTATAATTTTGTGTTTACATTTTACTGTGGGAGAGACAATGAAACTACCACATGTTGAGAGGCCACTGTTTGTTGTTTGGATCGCCCTCATGGTTATTGATTTTCATATCATGCCACAGAAATAA
Associated Phenotype:
Not determined