ZMP

hif1ab

Ensembl ID:

ENSDARG00000034293

ZFIN ID:

ZDB-GENE-040426-706

Description:

hypoxia-inducible factor 1-alpha [Source:RefSeq peptide;Acc:NP_956527]

Human Orthologue:

HIF1A

Human Description:

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Source:HGNC

Mouse Orthologue:

Hif1a

Mouse Description:

hypoxia inducible factor 1, alpha subunit Gene [Source:MGI Symbol;Acc:MGI:106918]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa16125	Nonsense	Available for shipment	Available now
sa23673	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa16125

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

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Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000018500	Nonsense	137	777	4	15
ENSDART00000047580	Nonsense	137	532	4	15

Genomic Location (Zv9):

Chromosome 20 (position 20410476)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	20	20438643
GRCz11	20	20338316

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

CTTTTCTCTCTCTTAGTTTGATCTGACCGGKCACAGCATCTTTGAATTTT[C/A]ACACCCATGTGACCATGAAGAGTTGAGAGAGATGCTCGTCCACAGAACAG

Long Flanking Sequence:

GGCCACCAATATTACATGCATTTCTAATATAAGTATTAAAATACACTAAATTGTTTAATAAAATATGTTCTTGCAATATTTTATTTATAGTAATACAAAACAATTAATAGGAATGTACCAAGTTAGCAACATGTGATTGTATTTTTTCTTATACAAACCACTTAGTATCAGGTGTAAACATGACCTTACATTTATTATATTGCTCAGGGATGTTATTCGATTTTGCAGATGAAAAAGAGGAGAAGGAGGAGAATGAGCTGGAAAGTCAGCTGAATGGCTTTTATCTGAAGGCCCTTGAGGGTTTCCTTATGGTCCTGTCTGAGGATGGAGACATGGTTTATCTCTCTGAGAATGTCAGCAAGAGCATGGGCCTCACACAGGTACCTCGACGTCTGCATTTTCTTCTAAGCATTTCGATTAAAAGCTTATGGTGTAGCTAAATATCCTTTCCTTTTCTCTCTCTTAGTTTGATCTGACCGGTCACAGCATCTTTGAATTTT[C/A]ACACCCATGTGACCATGAAGAGTTGAGAGAGATGCTCGTCCACAGAACAGGTGAGCCACACACGACACATTCATACCACTGATAAATCAGTCATTAATAACAAATGCATTAACGTTTGTCTTCATCCTTATCATCCATGTTTAGGATCCAAAAAGACCAAGGAACAAAACACAGAGCGTAGCTTCTTCCTGCGGATGAAGTGCACACTCACTAGCAGAGGACGCACCGTCAATATCAAGTCTGCGACGTGGAAGGTGACATTGTCTTTTCAAACTGTTGCTAATTGTAGTCATAGCTTATATATAGCCTTCCACATATCTATACCTTTTCCTGGTGTATTGTTCAAGAAGAATACAATTCGTAAAGCAGATTTTAGTTAAGGAAGTAGGAAAGAAAATAAGCTTGAGTCATTTTTTGTGAAGGATATTTATTTTGTAGTTTTTATTATGTACAGGGTTCATAAGGGTGCTGGAAATTCTTGAAAATGCGTGAAGTTTAAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa23673

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000018500	Essential Splice Site	504	777	10	15
ENSDART00000047580	None	None	532	None	15

Genomic Location (Zv9):

Chromosome 20 (position 20404069)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	20	20432236
GRCz11	20	20331909

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GCCAGACCCCACAAACACACCCTCCACATCTGGACTCGGCTCTTCGGGGG[T/C]AAACACTTATTAAACGCTTGCTATTCTTGGTCATTTAACAACAATTGCTC

Long Flanking Sequence:

TATAATGGGTGTGACAGACAATGTAGATAACCAAAACATGCAGTGTTGGTGGTCCTCCAGGCACATAGTTGAGAAACACTGCTTTAGAGGATTAAATGCAATCCCCTGGCAGCTTTTTATCTTATGAAGACTAACAACTCTTGTCATTCACTAATCATCTGAGATTACAGGAAATGTGCTTTCATAATTTTACTGAAGTAAATCTAATATTAAATACACACAGTTCCTTGGTGGTCTACCAATAATAATTACCGGTATCCATTTCCCTCCAGATTCTGACATACAGCTGCTGAAGGAGGTGCCCCTCTACAATGATGTCATGCTGCCTTCCAGCAGTGAGAAGCTGCCACTCAGCCTATCTCCTCTCACACCCAGCGACTCCATCCCAGCTCTGACCAAACTAGAGACTGGAGGAGAGGACTTCCCTTTCAGCTCTGCCTCTGATCGTGTGCCAGACCCCACAAACACACCCTCCACATCTGGACTCGGCTCTTCGGGGG[T/C]AAACACTTATTAAACGCTTGCTATTCTTGGTCATTTAACAACAATTGCTCCCTTGTAATGGTTAATGAGATACTGTCACTGACTTTAGGTTGTTTTTTTTTGTCAATCTTAGCCCAACAGCCCCATGGATTACGGTTTCCCAGTGGAACCAGACATCAGTTCTGAATTTAAACTCGACCTGGTTGAGAAACTGTTTGCTATTGATACCGAAGCAAAGACACCTTTTTCCACCCAGGTAACTTTTTATTTAAGATTTTAACTACATATTGTTTGTCTCACTCTCTCCCAAAATCAAATTCTAATTCAAATGAGCTTTATTGGCATGACTTGTCAAGTATTGCTTATATATTGCAAATATGAATATATATACACATGTACATAAAACACAATTACAGATTTGATAAGTACATATGCAAATAAAAAAGACTAAGTTTTTTATTTTATATTATTACAAAGAAAACGAAAGAAAAATAAATTATAAAAAAAACAATATTATAATA

Associated Phenotype:

Not determined