Busch Lab

ZMP

slit3

Ensembl ID:
ENSDARG00000034268
ZFIN ID:
ZDB-GENE-010306-4
Description:
slit homolog 3 protein [Source:RefSeq peptide;Acc:NP_571811]
Human Orthologue:
SLIT3
Human Description:
slit homolog 3 (Drosophila) [Source:HGNC Symbol;Acc:11087]
Mouse Orthologue:
Slit3
Mouse Description:
slit homolog 3 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1315202]

Alleles

There are 11 alleles of this gene:

Allele Name Consequence Status Availability
sa202 Nonsense Confirmed mutation in F2 line Not yet available
sa1569 Essential Splice Site F2 line generated Not yet available
sa35691 Nonsense Mutation detected in F1 DNA Not yet available
sa30677 Nonsense Mutation detected in F1 DNA Not yet available
sa14755 Nonsense Available for shipment Available now
sa11742 Nonsense Available for shipment Available now
sa9875 Nonsense Available for shipment Available now
sa42392 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa202
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 163 1515 6 36
ENSDART00000126199 Nonsense 164 177 6 6
ENSDART00000146299 Nonsense 164 1516 6 36
Genomic Location (Zv9):
Chromosome 14 (position 25601271)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24304362
GRCz11 14 24601607
KASP Assay ID:
554-0151.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTGTCTCTCATCTGCAGGCAACTGGACAGCAACCACATCAGCTGCATC[G/T]AAGATGGAGCCTTCCGAGCCCTGCGCGATTTGGAGATACTGTGAGTCCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1569
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Essential Splice Site 176 1515 7 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Essential Splice Site 177 1516 7 36
Genomic Location (Zv9):
Chromosome 14 (position 25591202)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24294293
GRCz11 14 24591538
KASP Assay ID:
554-1512.1 (used for ordering genotyping assays)
KASP Sequence:
TACAAAGTGAAACATGCCTTTTTTMTAACGTGTTCTGTCTTCTTTTTTCT[A/G]GCACTCTCAACAACAACAATATCACCCTCATCCCACTGTCAAGCTTCAAC
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa272
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 219 1515 8 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 220 1516 8 36
Genomic Location (Zv9):
Chromosome 14 (position 25589163)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24292254
GRCz11 14 24589499
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACTCCAACAACCTGCACTGCGACTGCCACCTGTCCTGGCTCTCTGATTG[G/A]CTGCGGCAGAGGAGGGGTTTGGCCCCTTTCACACAGTGCATGGCCCCCGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35691
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 413 1515 13 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 414 1516 13 36
Genomic Location (Zv9):
Chromosome 14 (position 25567330)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24270421
GRCz11 14 24567666
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAACCTGCTGTCCCTCTATGACAACAAACTTCAGACCATCAGCAAAGGCT[T/A]GTTCGCTCCTCTGCGTGCCATCAAAACCCTGTGAGTTACACACACACACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30677
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 768 1515 21 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 769 1516 21 36
Genomic Location (Zv9):
Chromosome 14 (position 25537865)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24240956
GRCz11 14 24538201
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGAAGGAAACCTCCTCACATCCGTTCCCAAAGAGCTTCCTAATCTGAAA[C/T]AACTGACACTCCTGTATGTATTTTTGCTCTTTTGATTGAATTTATTTATT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa28308
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Essential Splice Site 820 1515 24 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Essential Splice Site 821 1516 24 36
Genomic Location (Zv9):
Chromosome 14 (position 25533753)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24236844
GRCz11 14 24534089
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAGCTCAATGCTTTTTTTTTTTTTCATTTTCTTTTCATTCTTCTCTTTCA[G/T]AACTCTCCACGGAAATGACCTTTCAACTGTTCCGGAGGGAGCCTTCAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14755
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 1054 1515 30 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 1055 1516 30 36
Genomic Location (Zv9):
Chromosome 14 (position 25515239)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24218330
GRCz11 14 24515575
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GATTTCAAGCCTCTACACTGTGCTTTTGTTGTTTTCTTCAGATRTGAGTG[T/A]TTGCCTGGTTATGTTGGCCAGCAGTGTGAGCAGGATTAMAATGACTGTCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11742
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 1067 1515 30 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 1068 1516 30 36
Genomic Location (Zv9):
Chromosome 14 (position 25515200)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24218291
GRCz11 14 24515536
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGATGTGAGTGWTTGCCTGGTTATGTTGGCCAGCAGTGTGAGCAGGATTA[C/A]AATGACTGTCTGGAGAACAAATGTCAGCATGGGGCAGAGTGTGTTGACGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9875
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 1102 1515 31 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 1103 1516 31 36
Genomic Location (Zv9):
Chromosome 14 (position 25512675)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24215766
GRCz11 14 24513011
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TAAATGTTTAAAAATGTGTCCCTCTCACTTTTYTTAGTGGGCTATTCTGT[G/T]AGAATCATCCACCAATGGTAYTGCTCCAGAACACAAGTCCATGCGATCAG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa2743
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Nonsense 1269 1515 33 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Nonsense 1270 1516 33 36
Genomic Location (Zv9):
Chromosome 14 (position 25499243)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24202334
GRCz11 14 24499579
KASP Assay ID:
554-2728.1 (used for ordering genotyping assays)
KASP Sequence:
CTAAAAGCTTGGGCAAACTCCCCCGTCCCCCTGCTGTGGACCACAACACA[C/T]AGCTATACATAGGCGGTATGRRTCAAAGACACTTCAATGTTCATCTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42392
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000046112 Essential Splice Site 1367 1515 34 36
ENSDART00000126199 None None 177 None 6
ENSDART00000146299 Essential Splice Site 1368 1516 34 36
Genomic Location (Zv9):
Chromosome 14 (position 25497295)
Other Location(s):
Assembly Chromosome Position
GRCz10 14 24200386
GRCz11 14 24497631
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCCACTATGTGAACAGATGAGCTCCCAAGACCCCTGTGAAAGCAGCAG[G/T]TACACAAACACATACGCACTGGATACTAATGCCTGTCCTGATTTTGCAGA
Associated Phenotype:
Not determined