Busch Lab

ZMP

top2b

Ensembl ID:
ENSDARG00000034195
ZFIN ID:
ZDB-GENE-041008-136
Description:
DNA topoisomerase 2-beta [Source:RefSeq peptide;Acc:NP_001038656]
Human Orthologue:
TOP2B
Human Description:
topoisomerase (DNA) II beta 180kDa [Source:HGNC Symbol;Acc:11990]
Mouse Orthologue:
Top2b
Mouse Description:
topoisomerase (DNA) II beta Gene [Source:MGI Symbol;Acc:MGI:98791]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa11711 Nonsense Available for shipment Available now
sa23498 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa11711
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000029024 Nonsense 343 1613 9 35
ENSDART00000130695 Nonsense 348 1618 9 35
Genomic Location (Zv9):
Chromosome 19 (position 19721914)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 18275049
GRCz11 19 17733614
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTGGWACTCATGAGCTTTGTGATATTTTAGGGAGGAAGACATAKCGATTA[T/A]ATAGTGGACCAAATAGTGGGGAAATTGATTGAAGTTGTGAAGAAGAAGAA
Long Flanking Sequence:
TGTTTTGTTTGTATGCAACAGTTATAAAAGAAGATGATTATGCTTATGATTATTACTTATGCTGATTCTAAAATAAAACACATTCCTAATGCTAGAGAACAGCAATGCAATATTTTGCAACTGGGTTTAAAGAGGGTGATTTTAAAGATTTATCTTTTAAAGTGTGTTTAATTTTGCTCCTGGAAGGCCAACATACTGCATATTTTAGCTCCAACCAGCTTCTAAACATTTGAAACCAATTTTGCAATTGTACAAACACTGGAATTAGCTAGTTAAAGTCTCTAAGGTTTGTGTAATTGTAGTAAACTCAAGATTGTGTCCCTCCAGGAGCAGATTTGGACACTCCTGTACTAAACTGACAGCAAAAACACATCATTATCTGCAATACTCATTATGCTCAGTACTTATAAAGGTGTTTTTGGTCATGTCTCTCCAGCTTTTTTAAATGATGTGGTACTCATGAGCTTTGTGATATTTTAGGGAGGAAGACATATCGATTA[T/A]ATAGTGGACCAAATAGTGGGGAAATTGATTGAAGTTGTGAAGAAGAAGAACAAAGCCGGAGTATCTGTAAAACCATTCCAGGTAAATTTTTGCTACTCATTACCCCCTTATAATAATACTATCATATTCAGTATTACACATATATTCAGGGTCTTTGGTTTTTCATTCTCTGAAATTTTGGTGGCTCTGAGATGTTTAATTACTATGTTTTAATTATTTGTTTTGTTTATTTCAGGTTAAAAACCATCTATGGGTATTTGTAAATGCCCTTATCGAGAACCCAACCTTTGATTCTCAGACCAAGGAGAACATGACTCTACAGACCAAAAGCTTCGGTTCCAAATGTGCTCTCTCGGAGAAATTCATCAGAGCTGTGCGTGATAATCTCTTAACTTGATTCTCATGTTGTGATTAATCTTTTATTATACATAAGAGGTTGCATTTTCTGTGCACTTTACATTGCACTACAGCATTTAGATTTTTTAATGTGTTATTACAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23498
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000029024 Nonsense 401 1613 10 35
ENSDART00000130695 Nonsense 406 1618 10 35
Genomic Location (Zv9):
Chromosome 19 (position 19721588)
Other Location(s):
Assembly Chromosome Position
GRCz10 19 18274723
GRCz11 19 17733288
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAACCCAACCTTTGATTCTCAGACCAAGGAGAACATGACTCTACAGACC[A/T]AAAGCTTCGGTTCCAAATGTGCTCTCTCGGAGAAATTCATCAGAGCTGTG
Long Flanking Sequence:
GGAGCAGATTTGGACACTCCTGTACTAAACTGACAGCAAAAACACATCATTATCTGCAATACTCATTATGCTCAGTACTTATAAAGGTGTTTTTGGTCATGTCTCTCCAGCTTTTTTAAATGATGTGGTACTCATGAGCTTTGTGATATTTTAGGGAGGAAGACATATCGATTATATAGTGGACCAAATAGTGGGGAAATTGATTGAAGTTGTGAAGAAGAAGAACAAAGCCGGAGTATCTGTAAAACCATTCCAGGTAAATTTTTGCTACTCATTACCCCCTTATAATAATACTATCATATTCAGTATTACACATATATTCAGGGTCTTTGGTTTTTCATTCTCTGAAATTTTGGTGGCTCTGAGATGTTTAATTACTATGTTTTAATTATTTGTTTTGTTTATTTCAGGTTAAAAACCATCTATGGGTATTTGTAAATGCCCTTATCGAGAACCCAACCTTTGATTCTCAGACCAAGGAGAACATGACTCTACAGACC[A/T]AAAGCTTCGGTTCCAAATGTGCTCTCTCGGAGAAATTCATCAGAGCTGTGCGTGATAATCTCTTAACTTGATTCTCATGTTGTGATTAATCTTTTATTATACATAAGAGGTTGCATTTTCTGTGCACTTTACATTGCACTACAGCATTTAGATTTTTTAATGTGTTATTACAACTGAATGATTTCCCTTCACAGGCCACAAACTGTGGTATCGTGGAAAGCATTCTTAACTGGGTGAAGTTTAAAGCTCAGACACAGCTGAACAAGAAATGCTCCTCTGTCAAACACAGTAAAATTAAAGGTATTCCCAAACTAGATGACGCCAATGATGCAGGTGAGCTTATAGCAGATAAACTTATAGCTATATCTGTCAATTAGATTTGCACAACATGGGTCAAAACATATATTTCTGTTTTTTTGTTTTTTTCATAAAGCAAACTGAATAGATGATTAGGGCTTGCAAGGCTCTTTGTTTTATGGCCAATCACTATTCAATCTTTG
Associated Phenotype:
Not determined