ZMP
cpsf1
Ensembl ID:
ZFIN ID:
Description:
cleavage and polyadenylation specificity factor subunit 1 [Source:RefSeq peptide;Acc:NP_001108153]
Human Orthologue:
CPSF1
Human Description:
cleavage and polyadenylation specific factor 1, 160kDa [Source:HGNC Symbol;Acc:2324]
Mouse Orthologue:
Cpsf1
Mouse Description:
cleavage and polyadenylation specific factor 1 Gene [Source:MGI Symbol;Acc:MGI:2679722]
Alleles
There are 6 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa44909 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa36798 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa23476 | Essential Splice Site | Available for shipment | Available now |
| sa29173 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa16124 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa44909
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024861 | None | None | 985 | None | 24 |
| ENSDART00000045987 | Essential Splice Site | None | 416 | None | 12 |
| ENSDART00000110017 | None | None | 1451 | None | 37 |
| ENSDART00000110513 | Essential Splice Site | None | 400 | None | 15 |
Genomic Location (Zv9):
Chromosome 19 (position 12573605)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 12031951 |
| GRCz11 | 19 | 11950293 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATGAGACCCAGTGGCCAAAGAGCATAACAATCGTACACTTATTCTGTGG[T/A]ATGTTCGAGTTTATTTATGCGTATCTTCACTTACTTTTGTTATTGTCAAA
Long Flanking Sequence:
ATTTCTTTGACACTGTACAACAATATATATATATATATATATATATATATTATTTACATTACTGTGAGGGTTTGTTGAGGGTAGATGCAAAAAAAATTACACTTTAATTGTAATTTAATAAATAATGTGAATATTACATATCATAATTGCAGTTTTTACATTACTGTGATGGTTGGGTTTAGGGTTGGAGTAGTGGTAGACGTTAATAAAATACAATTAATTGATAATTTGATAAATAATCATATTCTAAATAATACTCGTTAACTTCCTACCGCAGCTGAATCTTTTCTAGTAACAACAAACAAAGCGCCAGGAACTCAAGTTTCGCACATTGGCCACACCGGACTCGTTTGAGCGCCGCACTTCTAGCGCGAGTCGTTCTGGGATGTGTAATGAATGAGAAAGTGCTGTCCAGTGTGCTGATAATGTGCACTTTTTAATGTCTGCATTCATGAGACCCAGTGGCCAAAGAGCATAACAATCGTACACTTATTCTGTGG[T/A]ATGTTCGAGTTTATTTATGCGTATCTTCACTTACTTTTGTTATTGTCAAATATAGCTAGCTAGCATATTAGCGTGAGGTGCAAATAATATCAACAACATGTTCGAATAGACAAGGGAAACCAATAACTCTCTACAATAAATCAGTAAATATGTGTTTATCAGTTATGGAGCAGTTAGAAGATGTGAAGTGCTGCTGTGGAGTTTGTGAAGAGTCAGACATGACGCATGAAGCACTACGTTAGTGTTGACTGTGTGTTTGGTTCATAAGGTGCTGAGAGGAGCCGCTGATCTTCATCATGTACGCGGTGTACCGTCAGGCTCACCCGCCCACCGCAGTGGAGTTTGCCGTTTACTGCAACTTCATCTCCAGCCAAGAGAAAAACTTGGTGGTGGCAGGAACATCTCAGCTGTACGTCTACAGGATCATTTATGATGTGGAGGTGAGGATGGAGAATGACGGATTCAGTATCTTAGTCAGAGCCCCTAGTTTTTCAGTTTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa36798
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024861 | None | None | 985 | None | 24 |
| ENSDART00000045987 | Nonsense | 54 | 416 | 3 | 12 |
| ENSDART00000110017 | Nonsense | 54 | 1451 | 2 | 37 |
| ENSDART00000110513 | Nonsense | 54 | 400 | 3 | 15 |
Genomic Location (Zv9):
Chromosome 19 (position 12568256)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 12026602 |
| GRCz11 | 19 | 11944944 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTAACATGAATCATTTTCCCTCATTTCATTCTAGAGCACTTCCAAGTCT[G/T]AAAAGTCATCAGGTAGGAATTTTACATGTATTTTTTTCTGCATTCAAGTA
Long Flanking Sequence:
CACTACGGACAATTTAGCCTACCCAATTTACCTGCACCGCGTGTCTTTGGACTGTGGGGGAAACCGGAGCACCCGGAAGAAACCCATGCGAAGGCAGGGAGAACATGCAAACTCCACACAGAAACGCCAACTGAGCCGAGGTTCGAACCAGCGACCTTCTTGCACTACCTACAGCATTAACTACTGCGCCACTGCCTCGCCCATCGCCCATTTCATTATTATTATAACAAGCAGTTTTAATAAGCAGATTGGAAGGATTTGTGTTGTATTGCATGACAGACCTGCCATACTTTTCCACACAAGACATGAAAATAAACAAATATTCTAAGACATAACATCTCTCATGCTTGGACCCCCACACTGTATCTTAGATATAAAAAACACACATTATATCATAATCAGTTTTAAGATGAAGATGTATTTTTTACTCTACAATGACCGGTATTTAATATTAACATGAATCATTTTCCCTCATTTCATTCTAGAGCACTTCCAAGTCT[G/T]AAAAGTCATCAGGTAGGAATTTTACATGTATTTTTTTCTGCATTCAAGTATGTTGTAGATTTTCTATTACTATTAATGTTATAATTACTATGTTCAATAATGAATCTTTGCAGATGGCAAGAGTCGTAAAGAGAAACTGGAGCAGGTGGCATCTTTCTCTCTCTTTGGAAATGTGATGTCAATGGCCAGCGTTCAGCTGGTGGGCACCAACAGAGACGCCTTGCTTCTCAGCTTCAAAGATGCCAAGGTATGTCTGACTGGATTAAAGCTAATTTTTATTGTTTACTTTATTTTCCACTTATTTAAATGTCTTTCTGTTCCCTTGTGTTATTCATGAGCTCCTTTAAACTACAAAAAGTTCCTTGTGTGTTTGTTCACACTTGGCGAATAATGCTCGTTCCAATTCTGTTATAATATCGAATGTCTAATATTTCTGCTATTTTGTGTCTTTCAGCTGTCAGTAGTGGAGTATGACCCTGGCACGCATGATCTCAAGACTC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa23476
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024861 | None | None | 985 | None | 24 |
| ENSDART00000045987 | Essential Splice Site | 180 | 416 | 6 | 12 |
| ENSDART00000110017 | Essential Splice Site | 180 | 1451 | 5 | 37 |
| ENSDART00000110513 | None | None | 400 | None | 15 |
Genomic Location (Zv9):
Chromosome 19 (position 12567461)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 12025807 |
| GRCz11 | 19 | 11944149 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGGAAGGACACGCTTGCTGACGAACAGGAGGGGATTGTGGGAGAGGGG[T/C]GAGAATAAATGTTTTCTAAATACTTGAAGACATTTCTTTTTTATTATTAT
Long Flanking Sequence:
CCACTTATTTAAATGTCTTTCTGTTCCCTTGTGTTATTCATGAGCTCCTTTAAACTACAAAAAGTTCCTTGTGTGTTTGTTCACACTTGGCGAATAATGCTCGTTCCAATTCTGTTATAATATCGAATGTCTAATATTTCTGCTATTTTGTGTCTTTCAGCTGTCAGTAGTGGAGTATGACCCTGGCACGCATGATCTCAAGACTCTGTCGCTGCATTATTTTGAGGAACCGGAGTTGAGAGTGTGTATTGTGGTTATGAGGAAGTGTTGTACTGCTGTTTTGTGGAGATTTGTGTGAGTTTTTGTGTTTGAATTGTGAAGAATTGTGTTTTTTTTGTATGTTATAGGATGGGTTTGTTCAGAATGTGCACATTCCTATGGTTCGAGTGGATCCAGAGAATCGATGTGCTGTCATGCTGGTGTACGGCACTTGCCTGGTGGTTCTGCCTTTCAGGAAGGACACGCTTGCTGACGAACAGGAGGGGATTGTGGGAGAGGGG[T/C]GAGAATAAATGTTTTCTAAATACTTGAAGACATTTCTTTTTTATTATTATTATTTAAAGACTTTTATGTTAAAAATAATAATATTGTGAAATAATGTTGATGTCGAAGCTGAATTTTAAACTCCAGATTTTAATGTCAAATGATCCTTCAGAAATTATTCTGTTATGCTGATTTCATGCTCAAAAGCATCAGTTATCAGTGTTTTTTGTTTTGCATTTTTGATCATTTTAATTTTTATTAAAACAATATAAAACTCCAAACGAAAGCATTTCGCATATGAAAAAGCATATAGCATATAAAAAGCATTTTATAATATGAATATCTTTTTTTCCCCTCAAACAATCCATCTCATGAACACTATGATAGTAATTGTAAAACAAACATCGCTACTTTTTAGTCACATATACACTTATTTATTAAACAACATACTTTACATGCCAATTTGCACATAACAGCTGCAAATATAACGTTGTTTATAGTCATATACCTGTACATACACT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa29173
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024861 | None | None | 985 | None | 24 |
| ENSDART00000045987 | None | None | 416 | None | 12 |
| ENSDART00000110017 | Essential Splice Site | 417 | 1451 | 11 | 37 |
| ENSDART00000110513 | None | None | 400 | None | 15 |
Genomic Location (Zv9):
Chromosome 19 (position 12561519)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 12019865 |
| GRCz11 | 19 | 11938207 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGAAACACCCATGGAGGAGGGCAAAGAGAATGAGGAGAAGGAGAAACAGG[T/A]TTGTAATTAAGTTAATTTATTTCAATTTACAATTGCAATTAAATGTAATA
Long Flanking Sequence:
CTTGGTATCTTACTGAAGACATATTATTAGGTGTTTTATTCCAAATCTGCTCCATTTTTATGAAAAATAAGATGATTATCGTTGTGTTCATAAATAGAAAGAGCAACTAATTGCTATTTTTATATCACATACACAATGGATGGATGTCAAATAGTCATTTGGGTCAGAGTTGTGATAGTGTGTGTTTTATTTCTCCAGTTATGTGTTGACGCTCATCACTGATGGCATGAGAAGTGTTCGTGCGTTTCACTTTGATAAGGCTGCTGCCAGTGTCCTGACTACCTGTGTGAGTGATCGGCTTAAAAACGACAGTCTTTGGTGCTCTTTATTGTTCAGTTTGTGTAAGTGACGGTTTCTGTCCTCTTAGATGATGACTATGGAGCCAGGCTATCTGTTTTTGGGCTCTCGCCTGGGAAACTCACTGCTGCTCAGGTACACTGAGAAACTCCAGGAAACACCCATGGAGGAGGGCAAAGAGAATGAGGAGAAGGAGAAACAGG[T/A]TTGTAATTAAGTTAATTTATTTCAATTTACAATTGCAATTAAATGTAATAAAATAAAATATTGTGGTTTAAATGTATTATAATTTCATCAAGTTGAACTTTTTTGGTCACTTCAGTATTATTTATTTACATCTTTGTGTAATAGAATTATTTTTGTACCTGAAATATGTTTAAAGTGCTTCTGAATTTACTGTCAAGCATTTATGTTATACTAAAACATTTCTATCGAAACTTTGTTGTTTTTCTAAATATAATTGTGTCTGTGTGTGTGTATATGTATGTGTGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGTACACACACACATATACACACACACGGTGTCAGAATTATTAACCCCCTGTTTATTTTTTTTCCCAATTTCTGTTTAACGGAGAGAAGATTTTTTTTTCAACATTTCTAAACATAATAGTTTTAATAACTCATTTCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16124
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000024861 | Essential Splice Site | 436 | 985 | 10 | 24 |
| ENSDART00000045987 | None | None | 416 | None | 12 |
| ENSDART00000110017 | Essential Splice Site | 902 | 1451 | 23 | 37 |
| ENSDART00000110513 | None | None | 400 | None | 15 |
Genomic Location (Zv9):
Chromosome 19 (position 12541088)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 19 | 11999434 |
| GRCz11 | 19 | 11917776 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTACGACCAGCARCAAGCTCARAGCAAYCTGAAAGTGCGCTTCAAGAAGG[T/C]ACARGCTGTATCAATAYTTACTCTCCTCAGGAWGTTTACTGTAATGGTAT
Long Flanking Sequence:
CTTATTTATTATTGTCTATTTAGTCACATAAAATTATAACCTAGTTACTTTTCACCACCTTGTATATCACTTGTTGTTTTTATCATTGTTCATTAAAACATTTATTGTAATTTCGAAATCAGATCTACCAGCTTCCAGACTGGCGTTTGGTTTTCCTGGTGAAAAATTTCCCAGTCGGTCAGCGTGTTTTGGTTGACAGCTCTGCCAGCCAGTCAGCTACTCAAGGGGAGCTTAAAAAAGAGGAAGTGACGAGGCAAGGTGACATTCCATTGGTCAAAGAGGTTGCTCTTGTGTCATTAGGCTACAACCACAGCCGTCCCTACCTTCTGGTGAGCTTAACACCGTTTTTGCTCTTCTAAATGAGATTGCGTTTTATCTTTCACTGAATCTGTCAATCAAATTCTTACAGGCTCATGTTGAACAAGAGCTTCTCATCTATGAGGCCTTTCCGTACGACCAGCAGCAAGCTCAAAGCAACCTGAAAGTGCGCTTCAAGAAGG[T/C]ACAAGCTGTATCAATATTTACTCTCCTCAGGATGTTTACTGTAATGGTATTTGAATGATGAGGAGGTTTTTATTTTTCTTCATATCAGATGCCTCATAACATTAACTACAGAGAGAAGAAGGTCAAAGTGAGGAAGGACAAGAAGCCTGAGGGTCAGGGAGAGGACACTCTCGGCGTCAAAGGTCGTGTGGCCAGATTCAGATACTTCCAGGACATCTCTGGATACTCAGGGGTACGTCTGTCTGTGAATGTAATGCATATTTATGGTTATTTTATCTATTTTGAGCTATTTCAGCAGATTGAATCTAATAATAGTTTTAGTTTTGTCAACAATAACAAATCAAATTCAAGTTTTAAGAGTGTGCATATAACTTAAATTAAATGAGTTGTCTAAATATGCAGAAATTTCCATGTGTTTTACAAAATTCCTCCTTCAGATATAAGATTAATGGTTACACTGTAAGTTGCAAGAATAGTGGGATACATAGATGAACAATAAA
Associated Phenotype:
Not determined