ZMP
zgc:136354
Ensembl ID:
ZFIN ID:
Description:
mitogen-activated protein kinase kinase kinase kinase 2 [Source:RefSeq peptide;Acc:NP_001038725]
Human Orthologue:
MAP4K2
Human Description:
mitogen-activated protein kinase kinase kinase kinase 2 [Source:HGNC Symbol;Acc:6864]
Mouse Orthologue:
Map4k2
Mouse Description:
mitogen-activated protein kinase kinase kinase kinase 2 Gene [Source:MGI Symbol;Acc:MGI:1346883]
Alleles
There are 7 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa16484 | Essential Splice Site | Available for shipment | Available now |
| sa16426 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa16484
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000100351 | Essential Splice Site | 524 | 889 | 20 | 32 |
| ENSDART00000100351 | Essential Splice Site | 524 | 889 | 20 | 32 |
Genomic Location (Zv9):
Chromosome 21 (position 33024883)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 34024576 |
| GRCz11 | 21 | 34059066 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TAATCATTACCAAACTTTAATCAGTCTCTCRCAATTTATTACTTATAAAA[G/T]AAAGCTGTTGTCMATGGACTGCCACCTAMACCACAAGTACATGTAAGTAC
Long Flanking Sequence:
CCCCCATTTAATTTTTTTTCTTTTTTAAATATTTTCAAAATGATATTTTACAGAGCAAAGAAATTTTCAAAGTATGTTTGATAATATTTTTTTCTTCTGGAGAAAGTCGTATTTGTTTCATTGCGGCAAGAATAAAAACAGTTTTTAATTTTTTAAAAGCCATTTTAAGGTCAAATTATTAGCCCCTTTAAGCTATATATTTTTTCGTTAGTCTAGAGAACAAACCATTGTTACACAATAACTTGCCTAATTACCCTAAGCTTGCTAGTTAGCCTAATTAACCTAGTTAAGCCTAAACCTAGTTAAAGAAATTTGTTGAAAAAATCTTCTCTCCGTTAAACATAAATTGGGGTAAAAATAAACAGGGAGGCTGATAATTCTGACTTCAACTGTATTTTAAAATATTATACTAATTAATAAAGTCAAACTGTGTTTGAGAATGTCTCAAGGTAATCATTACCAAACTTTAATCAGTCTCTCGCAATTTATTACTTATAAAA[G/T]AAAGCTGTTGTCAATGGACTGCCACCTACACCACAAGTACATGTAAGTACAGAATAATTAGCCCTAATTCTGTTGCATGCCTTAAATTCATGCTTATTTTTCTGTGATGATCCTACATTGTCTTCCAGATGGGGGCCTGCTTCTCCAAAGTATTCAACGGCTGTCCATTAAAGACTCACTGTGCTGTTACATGGGTTCTACCTAAAACCAGAGGTACTTTAGTTAGCAGCTTTTTACTTAAAGTTGCTATTTATATTATAACTTTTTGGGACTAAAATGATCCAAAATCTATTTTTTAACAAGTACATGCCTGTAATTAGAACTGTCCCGATGAGGTTTTTTTGCCCCCGATTCGAGTCATTTGATTTGGAGGATCTACCAATACCTAAACCTGATCCAATACTTTTCTAATACATAAAAAATAATAAAGAAAAGGGAAAGAAACAGATCCAGGATGTTCCTTATTTTTTATTTAATTCACATTTTTGAACATATAACAT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16426
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000100351 | Essential Splice Site | 524 | 889 | 20 | 32 |
| ENSDART00000100351 | Essential Splice Site | 524 | 889 | 20 | 32 |
Genomic Location (Zv9):
Chromosome 21 (position 33024883)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 21 | 34024576 |
| GRCz11 | 21 | 34059066 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TAATCATTACCAAACTTTAATCAGTCTCTCRCAATTTATTACTTATAAAA[G/T]AAAGCTGTTGTCMATGGACTGCCACCTAMACCACAAGTACATGTAAGTAC
Long Flanking Sequence:
CCCCCATTTAATTTTTTTTCTTTTTTAAATATTTTCAAAATGATATTTTACAGAGCAAAGAAATTTTCAAAGTATGTTTGATAATATTTTTTTCTTCTGGAGAAAGTCGTATTTGTTTCATTGCGGCAAGAATAAAAACAGTTTTTAATTTTTTAAAAGCCATTTTAAGGTCAAATTATTAGCCCCTTTAAGCTATATATTTTTTCGTTAGTCTAGAGAACAAACCATTGTTACACAATAACTTGCCTAATTACCCTAAGCTTGCTAGTTAGCCTAATTAACCTAGTTAAGCCTAAACCTAGTTAAAGAAATTTGTTGAAAAAATCTTCTCTCCGTTAAACATAAATTGGGGTAAAAATAAACAGGGAGGCTGATAATTCTGACTTCAACTGTATTTTAAAATATTATACTAATTAATAAAGTCAAACTGTGTTTGAGAATGTCTCAAGGTAATCATTACCAAACTTTAATCAGTCTCTCGCAATTTATTACTTATAAAA[G/T]AAAGCTGTTGTCAATGGACTGCCACCTACACCACAAGTACATGTAAGTACAGAATAATTAGCCCTAATTCTGTTGCATGCCTTAAATTCATGCTTATTTTTCTGTGATGATCCTACATTGTCTTCCAGATGGGGGCCTGCTTCTCCAAAGTATTCAACGGCTGTCCATTAAAGACTCACTGTGCTGTTACATGGGTTCTACCTAAAACCAGAGGTACTTTAGTTAGCAGCTTTTTACTTAAAGTTGCTATTTATATTATAACTTTTTGGGACTAAAATGATCCAAAATCTATTTTTTAACAAGTACATGCCTGTAATTAGAACTGTCCCGATGAGGTTTTTTTGCCCCCGATTCGAGTCATTTGATTTGGAGGATCTACCAATACCTAAACCTGATCCAATACTTTTCTAATACATAAAAAATAATAAAGAAAAGGGAAAGAAACAGATCCAGGATGTTCCTTATTTTTTATTTAATTCACATTTTTGAACATATAACAT
Associated Phenotype:
Not determined