ZMP

si:dkey-267i17.6

Ensembl ID:

ENSDARG00000033104

ZFIN ID:

ZDB-GENE-060526-280

Description:

Novel protein similar to vertebrate transmembrane channel-like 2 (TMC2) [Source:UniProtKB/TrEMBL;Acc

Human Orthologue:

TMC2

Human Description:

transmembrane channel-like 2 [Source:HGNC Symbol;Acc:16527]

Mouse Orthologue:

Tmc2

Mouse Description:

transmembrane channel-like gene family 2 Gene [Source:MGI Symbol;Acc:MGI:2151017]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa44620	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa11141	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa44620

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000073638	Essential Splice Site	66	430	2	9
ENSDART00000144087	Essential Splice Site	261	761	7	17

Genomic Location (Zv9):

Chromosome 5 (position 55833548)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	5	54618218
GRCz11	5	55241054

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CGCTGAGACAGCTGACAATAAATACGCCTCCATCACCACCAGCTTCAAAG[T/A]ATGTGCTTATGTGCATTTGTGGAAATGATTGGGTAGGTGTTCATGTATGT

Long Flanking Sequence:

CTTGCTCTATGATAATAACAATCTTCCCTTCCACCCATTGAAATTAGGAGAGACTATTTTATTTTGAACAATGATGCTCATATAATGTTTTCGAAGTGTTCAAATCAGTCTACGTTCATCTCTTTAGCTCAAATCGGGACAGCAGACATTGTAAGTCTACTCTTTTATAAACACCTCACCTTTAAAATGAAATCTTCACTCCAGTCAGCATAGCAGTACGATTGTGTGATTTATTAGTATTATTAAACCCTTGTTGTTATTTTGAATGCAATTGGAAATTGCGCTTCTGTTATCCTGCCGGCGAGAATGGATTCTCTACAAGTGTTGAATAAAGTCCACTCTCGCTGTTAGGATGGCTAAAAACGCAGATGTGGGGGGAGGGGACGGAGAAGACAATGAGTTCACCTTTGCCTGGAAGATGTTCACCAGCTGGGATTATCTTATTGGGAACGCTGAGACAGCTGACAATAAATACGCCTCCATCACCACCAGCTTCAAAG[T/A]ATGTGCTTATGTGCATTTGTGGAAATGATTGGGTAGGTGTTCATGTATGTGTGCTGACCACAGCAGTTTTTTTCACAGTGTTGTGGTTATTTCAGACATCTGAGAAGGTCAACTCTCTAAAAGACAAAGATTTATGAATATATATATATATATATATATATATCCTAAATGCTCTGTAGTTCCACTATGTGTTTTTCTCAGTTGAGATGTTCTAATGCATTCTACAGGAATCCATTGTGGATGAGCAGGAGAACCAAAAGGATGAAAACATTCATCTGAGAAGATTCTTACGTGTCCTAGCCAACTTTCTCATCACCTGTACATTGGGTGGAAGTGGCTATCTCATCTATTTTGTAGTCAAACGCTCTCAAGAGTTTCAAAACATGGACAACCTCTCATGGTATGAGAAGAATGAGGTAAAGATATACACGTCCAGATTTAATATCTTTTCTTGATCTGATATTTTTATTTTTTGCATTGACAAAAACTGATATGCATTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa11141

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000073638	Essential Splice Site	388	430	9	9
ENSDART00000144087	Essential Splice Site	583	761	14	17

Genomic Location (Zv9):

Chromosome 5 (position 55840195)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	5	54624865
GRCz11	5	55247701

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

ATAACTTATMTTATGAACATTTATTCATAACTGTTCATYCTGTTACTGTA[G/A]TGGAAAGGAAAGAATGTTYGACGTTGTTATGGAGACCATTGATCTGGATC

Long Flanking Sequence:

CCATATTGGGTGAACTAACCCTTTAATGTGATAAGAACCATTTAGGTGTACTTAAATGAATGTGCATCCATGGCTCATTTTTGTCCTCATATGTACACTTTTAAAATGTAACCAAACAAGAATAAGCTACCTAACACTTCTTTACCTGAATATTTATAAAGCTGTTTTCTGTGTTTGTCAGGATGGGGGCATTCTATGCTCCCGGTCTTGTAGGCATCAATGTTCTGCGGCTCCTTTCATCTATGTACTATCAATGCTGGGCTGTAATGGCCTGTAATGTCCCACATGAGAGGGTCTTTAAAGCTTCTAAATCCAATAACTTCTACATGGGCCTGTTATTGCTCATCCTCTTTCTGAGTCTCCTACCTGTGGTTTACACCATTATGTCTTTGCCACCATCTTTTGATTGTGGACCTTTCAGGTACTAAAAGCATACTATAATAGCCCAAAATAACTTATATTATGAACATTTATTCATAACTGTTCATCCTGTTACTGTA[G/A]TGGAAAGGAAAGAATGTTCGACGTTGTTATGGAGACCATTGATCTGGATCTACCAGCATTTATGGGGACTCTCTTTGGATATGTCGCAAACCCGGGACTCGTTATATCTGCAGTACTTCTCATGGTGTAAGTGAATTATTTAAAATGGCATGATCACATACTGCAGGTAGGGATGAGTGGGTAGCACTGACATTTTTTTTTTTTTTTTGCAGCAACTAAGTTCCCTAGTTCAAATCCTGATTGTGCCAGAACATATTTCTTTATGGGGTTTCATGTATTTGATCACATGTTAATATCACATACAAAATAAGTGAAATTTGCAGTTTTTAAACATTCTATTGTAAAGCTTTTATTTCCCCTTTTTTGCACATGCTTTTTTCATATTTGATCATATGGGTTTCACTTGAAATGTTCAAAACAACATTTCACATGCTCAACAGGTATCACATTGGATTTGTAACATGAAGCTATGTTATAAAGCATGTATCTAAGTTACTAGA

Associated Phenotype:

Not determined