Busch Lab

ZMP

cthl

Ensembl ID:
ENSDARG00000032206
ZFIN ID:
ZDB-GENE-040905-3
Description:
cystathionase (cystathionine gamma-lyase), like [Source:RefSeq peptide;Acc:NP_001005400]
Human Orthologue:
CTH
Human Description:
cystathionase (cystathionine gamma-lyase) [Source:HGNC Symbol;Acc:2501]
Mouse Orthologue:
Cth
Mouse Description:
cystathionase (cystathionine gamma-lyase) Gene [Source:MGI Symbol;Acc:MGI:1339968]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa26780 Nonsense Mutation detected in F1 DNA Not yet available
sa11242 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa26780
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104200 Nonsense 153 400 5 12
ENSDART00000136314 Nonsense 157 404 5 12
Genomic Location (Zv9):
Chromosome 6 (position 37350213)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 37423971
GRCz11 6 37401865
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGTAACTAAAATATGGTATTAAATATTCCCGTTATGACAGATGGTTTG[G/A]TTTGAAACCCCCACAAACCCTACATTAAAGGTTGTGGACATCCAGGCCTG
Long Flanking Sequence:
CTTTTGCCTCTGGAATAGCAGCGACTGCGACCATCACCCATCTTTTAAAGCATGGAGATGGAATTGTGTGCATGTATGATATATATGGAGGTGGGTTGTGGCTCCTGCAGTATTAATGTAAAAAATTGTTACATCTAAAGTGTGAACTGTGAAGAGTCATTTTTTTTCTGAAATTGATAATACATTCATTTATTTTTTTGTTTTTTTTCCCACCAGGAACTAAAGAATATTTCAGAGAAATAATTACAGAATTTGACATTGATGCATCTTTTGTTGACTTCACAAAGCTGGAGGAGCTGAAAGCAGCTTTAAAACAAAATACAAAGGTACAGCGGAGAACATTTTTTCCAAGAATATACTGACGTCTTAAAATGTTTCTTTGACATTTTTGAAAATCCACATTTAAACCTTGATTTTTTTTTGTGTTAAACGTTACCACAGGGGTTTACCTCAGTAACTAAAATATGGTATTAAATATTCCCGTTATGACAGATGGTTTG[G/A]TTTGAAACCCCCACAAACCCTACATTAAAGGTTGTGGACATCCAGGCCTGTGCAGATATTGTGCATAAACACAACAAGGACACACTTGTTGTTGTGGACAACACATTCATGTCTCCCTACTTCCAGGTACACACACTTATTTTATGCACAATCATAAGCCAATGTTGCTTTTATCTAATCTATAAATCTAATTTGAATACATCAGGCAATATAAAGTTAGAAAGTACAATACTTGTTCCAGTTTTAAGAAATTCAAGGGCAAAGATATTTTTTTATACTGAAGCTAGATAAATATAAATAGAAAACTAAAATAATTAAAATAGAAATATTTCTTAAATATTTTTCATCCCTGAAACAGCGCCCCCTTGCACTTGGAGCGGACATCTGCATGTGCTCTGGAACAAAATATATGAATGGTATTAAGCTAATAATAGTATAAGTTAGATGCTTCATATCTAATTGAAATTGAACCGATTTGAAATAAAATGATTTGATGATTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11242
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104200 Essential Splice Site 332 400 9 12
ENSDART00000136314 Essential Splice Site 336 404 9 12
Genomic Location (Zv9):
Chromosome 6 (position 37344953)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 37418711
GRCz11 6 37396605
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATAAAAGGAMAACTTGAGCATGCCTCAACCTTCCTCAGCAATCTGAAGG[T/A]GCTCAAAAGCATCMTAYTGTTGAAAAATCTTTWACATCTTRTGTTTTTTT
Long Flanking Sequence:
TTAATAAATTTAGATCAATAGAAAATAACATATGATTTACTAACCAGTTCTTTTTTGGAATAATAGACGTATGTTCTTCTTATTATTCTTTTTGCTAAATGAAAAACAAATTTTGCCACAGAGCAAAGAAAAGATTTTTAGAGTAAGAAAGACCTCTACATAAAGAAACAATACTAGAAGAGATAGCTCCAATTACAGAGGCAACATGTCTTTATTATGAGTTTTGATCAGTTTAATGTGTACTTACTGAATAAAATTATGACATATTTAAAATCTAATTTCAAACTTTTTAACGATAGTGCCAATGTCAACATACCTGAGCTATTTCGCTAAAAATAACTGATATCAATTAACTTTTGGTATTTTTTTTTCTTCAGGTCTTCCTTCTCACCCTCAACATGAGCTGGCAAAAAGACAGTGCCGAGGCTGTTCTGGGATGGTCTCGTTCTACATAAAAGGACAACTTGAGCATGCCTCAACCTTCCTCAGCAATCTGAAGG[T/A]GCTCAAAAGCATCCTATTGTTGAAAAATCTTTAACATCTTATGTTTTTTTTGACTATGTTCTATTCTGAATTCCAGGTGGTTGCACTTGCTGAAAGTCTTGGTGGTATTGAGAGTCTAGCAAAGCTTCCGTAAGTACTGAGGTGCACTACTGAGAGGAATTTTCACTGAATATTGTGTTTATGAAAAGCATCTTTGTTTTTTTTTAATGAGTGTTTATGTGGGTGTTAGTTTTAAAAAGGTTTAAGAGTGCTCAGTTCGAATGACCACAAGGGGGCGCAAGCACTTTAATGTTTACCAACAGAAACGAGTCGACGCTTTTGATGCCTGAATATTTTGCATCCGATGTACGTTATTTAGCGAGAACTAATTAAACATTTCTTTAGGTCATACTATAATACTCGGCCTACAGTGTAAAAGCAAAGTTAAAATTGGTAATACAAGTCTCATGAAACGTCATTGTGTCAGATTTGAGATGCTTTTGTTCTCAAGTAATTTACAA
Associated Phenotype:
Not determined