Busch Lab

ZMP

nos2b

Ensembl ID:
ENSDARG00000031976
ZFIN ID:
ZDB-GENE-080916-1
Description:
nitric oxide synthase 2b, inducible [Source:RefSeq peptide;Acc:NP_001106973]
Human Orthologues:
AC015688.1, NOS2
Human Description:
nitric oxide synthase 2, inducible [Source:HGNC Symbol;Acc:7873]
Mouse Orthologue:
Nos2
Mouse Description:
nitric oxide synthase 2, inducible Gene [Source:MGI Symbol;Acc:MGI:97361]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa35915 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa8873 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa35916 Nonsense Mutation detected in F1 DNA Not yet available
sa364 Nonsense Available for shipment Available now
sa42569 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa35915
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048847 Essential Splice Site 19 1077 2 26
Genomic Location (Zv9):
Chromosome 15 (position 29706296)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 30444599
GRCz11 15 30325340
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCAGGTCACTCACAAGAGCGAACTACTGCAGCAGATGAAACCGGATATGG[T/C]GAGTCAAACTTTAACTAACATGAAATTAAATGTGATTAAGTAAATAGTAA
Long Flanking Sequence:
ACAACACTTTCAAATAGCATGGGACACAACAGAAATGTTTCAAAAAGACACTAAAATGTGACCGACCTGGCAATTTCTGTTATGGTTATTTAGGCTAATAAATTACAAAAGACAAGGAAATCAGGATGTGAAAATAAACAAACAAAAAACTCACTTTTTAAAGACCACCTACAACTTCATTGTGCATAGTCTTTTCATAGTTTTTAATATGTATGTGTTGTGAGGATATCTTCAAATGGATTAAGATCTTTTTTTAATTTGCAGGCTTTTTGGTAATTGTATGTATTTTCTTAAATTGCAGCACGTTATACTCTCTTAGCCAGCGTAGTATTGCTCCTTTGCTAAAACTTTAAATCCTCCTGTGTTATTTTTTATTTGACAAACATCAAAAACTATTGACTGCAATTTTTGATGAAACTGATCTGCAGTATTTCAGAAACACATGGGCAACCAGGTCACTCACAAGAGCGAACTACTGCAGCAGATGAAACCGGATATGG[T/C]GAGTCAAACTTTAACTAACATGAAATTAAATGTGATTAAGTAAATAGTAATGTTATGTTGGTTTTCTAGCAATGGGAAAATAAAGTCAAGCAGTGCCCATTTTCTAAGCAATTAAAGAACTATCAGGATAGTTCGTGCCATCAAGATGTGTTACATCACAGAGCGGTTAAGGTGAGGTATTATTGCATTAAACACTCACTAGGAATATATTTCTCTATAGAGGTAAAAGACCAAAAGAGTTTTATCAAGCATCAAAACGTAAAAGTGGAATACTGCTGTTATAAACCTTGAAAACACCTTGCTCCAGTCACAGCTTTTGTGCCTGTATTTCTGAGAGAGTAAGAAAAGTTTCTTGTTTTTATTTTAGAGCCATATTTGTTCGTCTAAGATTTGTGAAGGGTCAATCATGACTCCAAAATCTTTGACGCGCTGTCCCATGACCACTTTGCATTGTTCTGATGACATCCTCGTGCAAGCTGTTGACTTCATCAATCAATACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8873
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048847 Essential Splice Site 20 1077 3 26
Genomic Location (Zv9):
Chromosome 15 (position 29706365)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 30444668
GRCz11 15 30325409
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATGAAATTAAAYKTGATTWAGTAAATAGTAATGTTATGTTGGTTTTCTA[G/A]CAATGGGARARTAAAGTCAAGCAGTGCCCATTTTCTAAGCAATTAAAGAA
Long Flanking Sequence:
GCAATTTCTGTTATGGTTATTTAGGCTAATAAATTACAAAAGACAAGGAAATCAGGATGTGAAAATAAACAAACAAAAAACTCACTTTTTAAAGACCACCTACAACTTCATTGTGCATAGTCTTTTCATAGTTTTTAATATGTATGTGTTGTGAGGATATCTTCAAATGGATTAAGATCTTTTTTTAATTTGCAGGCTTTTTGGTAATTGTATGTATTTTCTTAAATTGCAGCACGTTATACTCTCTTAGCCAGCGTAGTATTGCTCCTTTGCTAAAACTTTAAATCCTCCTGTGTTATTTTTTATTTGACAAACATCAAAAACTATTGACTGCAATTTTTGATGAAACTGATCTGCAGTATTTCAGAAACACATGGGCAACCAGGTCACTCACAAGAGCGAACTACTGCAGCAGATGAAACCGGATATGGTGAGTCAAACTTTAACTAACATGAAATTAAATGTGATTAAGTAAATAGTAATGTTATGTTGGTTTTCTA[G/A]CAATGGGAAAATAAAGTCAAGCAGTGCCCATTTTCTAAGCAATTAAAGAACTATCAGGATAGTTCGTGCCATCAAGATGTGTTACATCACAGAGCGGTTAAGGTGAGGTATTATTGCATTAAACACTCACTAGGAATATATTTCTCTATAGAGGTAAAAGACCAAAAGAGTTTTATCAAGCATCAAAACGTAAAAGTGGAATACTGCTGTTATAAACCTTGAAAACACCTTGCTCCAGTCACAGCTTTTGTGCCTGTATTTCTGAGAGAGTAAGAAAAGTTTCTTGTTTTTATTTTAGAGCCATATTTGTTCGTCTAAGATTTGTGAAGGGTCAATCATGACTCCAAAATCTTTGACGCGCTGTCCCATGACCACTTTGCATTGTTCTGATGACATCCTCGTGCAAGCTGTTGACTTCATCAATCAATACTACAAGTCAGTTAAAAAGTAAGTTTAACCTTTCTATTCTGTTCATTTTTTGCTGACGTCCTGAAAGGACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35916
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048847 Nonsense 65 1077 4 26
Genomic Location (Zv9):
Chromosome 15 (position 29706698)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 30445001
GRCz11 15 30325742
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTTGTTTTTATTTTAGAGCCATATTTGTTCGTCTAAGATTTGTGAAGGGT[C/A]AATCATGACTCCAAAATCTTTGACGCGCTGTCCCATGACCACTTTGCATT
Long Flanking Sequence:
CAATTTTTGATGAAACTGATCTGCAGTATTTCAGAAACACATGGGCAACCAGGTCACTCACAAGAGCGAACTACTGCAGCAGATGAAACCGGATATGGTGAGTCAAACTTTAACTAACATGAAATTAAATGTGATTAAGTAAATAGTAATGTTATGTTGGTTTTCTAGCAATGGGAAAATAAAGTCAAGCAGTGCCCATTTTCTAAGCAATTAAAGAACTATCAGGATAGTTCGTGCCATCAAGATGTGTTACATCACAGAGCGGTTAAGGTGAGGTATTATTGCATTAAACACTCACTAGGAATATATTTCTCTATAGAGGTAAAAGACCAAAAGAGTTTTATCAAGCATCAAAACGTAAAAGTGGAATACTGCTGTTATAAACCTTGAAAACACCTTGCTCCAGTCACAGCTTTTGTGCCTGTATTTCTGAGAGAGTAAGAAAAGTTTCTTGTTTTTATTTTAGAGCCATATTTGTTCGTCTAAGATTTGTGAAGGGT[C/A]AATCATGACTCCAAAATCTTTGACGCGCTGTCCCATGACCACTTTGCATTGTTCTGATGACATCCTCGTGCAAGCTGTTGACTTCATCAATCAATACTACAAGTCAGTTAAAAAGTAAGTTTAACCTTTCTATTCTGTTCATTTTTTGCTGACGTCCTGAAAGGACCAGTTCAAATCAGTTCAAATAGACTCGATGAAAAACAACAAAGAATTTAGATTCTAACAATATATTTTTATGTATAGAAACACTTTATTAAACATTACAAAAAACATTTCTGAACATATGAATTACAAAAAAAAAAAAAAACTTTTTTTGGTGACAAATTTTGGAGACCTTTTGCACATTTGTATTGACTTGTTGCTTTTTGTTATCATTAAATTATTACATTTTTTTCCAAAAATACCTCATCCTCTGTTCTTATTATACTTTTTTTGGTTCAGTGAATTTGACTTTGAAATGCCTACATGAAAGGGCACCCTTGATGTAGAGCATTACAATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa364
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048847 Nonsense 163 1077 6 26
Genomic Location (Zv9):
Chromosome 15 (position 29708420)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 30446723
GRCz11 15 30327464
KASP Assay ID:
554-0234.1 (used for ordering genotyping assays)
KASP Sequence:
ATGTGATTTATATTATGTGGTATTTTTCTGTGCAGTTGTTTGATGCGCGT[A/T]AATGCCAAACTGCTGAGGACATGTTTCAGATGTTATGTGATCATATTCAG
Long Flanking Sequence:
AGATGCTACTGGATCATATCAACTCACCACAAAAGAGCTGGAATTCGGGGCTAAACAAGCATGGAGGAATGCTCCAAGATGCATTGGCAGAATTCAATGGGCTAATTTGCAGGTAGTTTATCTAGTTTGAACCTAAAATTATATATAGTTCACCTCAAAATTAATATTTTATTTACCCTCACCCTCCACTTCTTGTTACGTCTCTTTCCTTTGTTGAACACGAAAGAAGATACTTTGAAGAATGGGGGAAACCAGTAGCCACTGACTCCCAAGCTATTTTCTTTTTTGTTTTTTTCTTCTATGGATGTCATTGGCTACCATTTCCTACATTCTTTAAAATATCTTTTGTGTTCAACAAAAGAACCACTTGAGAGTAAATGATGTTTTTTTTTTTTTTGGGGGGGGGGGGTGAACTATCCCTATAAAGATATATTAAACCTGTATTTACAAATGTGATTTATATTATGTGGTATTTTTCTGTGCAGTTGTTTGATGCGCGT[A/T]AATGCCAAACTGCTGAGGACATGTTTCAGATGTTATGTGATCATATTCAGTTTGCTACCAATGGAGGCAACCTGAGGTAAACTGAGAATGTTATTCCACGTTTTCATGAAATCTTGATTGCCTGTGCAAAATTGATGAGATGTTGATGCAATAAAGATCTTTATTTTGACAGGTCTGCCATCACTGTGTTTCCTCAAAGAGCTGATGGCCAGCATGATTTCCGTGTGTGGAATAGTCAGCTCATACGATACGCTGGCTATAAGATGATAGACGGCACATTATTAGGAGATCCTGCCAGTGTTGACTTCACTGAGGTAAATTTTGTATTGCTTGATACTTTTTTAGTTTCTACAGTAGATATTTTGGTATCACTTTATGGTAAGGTTCCATTGGTTAAAGAGATATTCACCTAAAACTGAAAAATCTGATTGTTTACATATCCTTCAATTTTCACAGATCTGTTTGAGTTTCTTTTATCTGTTGAACAATAATATATTTTG
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037		 whole organism
ZFA:0001094		 quality
PATO:0000001		 normal
PATO:0000461

Mutation Details

Allele Name:
sa42569
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000048847 Essential Splice Site 754 1077 19 26
Genomic Location (Zv9):
Chromosome 15 (position 29722548)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 30460851
GRCz11 15 30341592
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAATCCTATCAACCAGAGCCTTCAGCTGGAATTCCTCAGTGCCCATGCTG[G/A]TACTGAACCATCTAATTACATAATGGATGTCTAACTCATAATAACATAAT
Long Flanking Sequence:
ATCAAACTTGATGGTTAAAATTACCTGCATTGGTCATATTTTGATATGATCTTTCTGATTGGAGAGGTGAAGGGAAAGAAGAAAGGGGAGACTGATCAAATGTAAATGCTTTGCCAGTTTCACTCAGCTGGGTGTGTGGAGGCAAGTTTTGTGTTTATAAACTGTGTATTCTTGCATTGTCCATATGTGGACACATCGAAGTATCTGAGGCATCACAATGTATCTGAGATATCTCAAATCTTACAATATTATTAGTTTTTTTTCTGAAACATATAAAAACCTCAATATTTTTATTATTTTACTTGTACTCAGTTGTGCTACAATATTGGTGGAGCTGGAAATGGAAGGAAACACAGAGCCCTTAAACTTCACCCCAGGAGACCATGTGGGGATTTTCGCAGGGAACTCACCTGGATTAGTGGCTGGCATCTTAAAGCATCTGTCCAATGCCAATCCTATCAACCAGAGCCTTCAGCTGGAATTCCTCAGTGCCCATGCTG[G/A]TACTGAACCATCTAATTACATAATGGATGTCTAACTCATAATAACATAATGATATCTAATAACTCTGTTCTATAGATGGTGAAAGGTGGCAGAGAGATGAACGAATACCGCCATGCTCTCTTGCCCAGGCTCTCACCTACTATCTGGACGTCACCAGCCCACCCTCTCAAAGCCTCCTCCGCAAACTCTCAAAGATAGCCAGACAGGAGGATCACAGACAGCACTTGCTCGCTCTGGCATCAGTAAGTCACTTTTTGATGATTGCAGGGGCTGTAGAACTGGGGATGAGAACTGCAAGATATTTTGTTGTTAGCTTAGTAACTTTAAGGCCCTGGTTTATGTAAAAGGTTCTTTTTCATCATTTATTTGAGGGCCAAAATAAGTTCATTTTGTTTACAATCACGTCATTCCAGTAGTCTGATTTTGCTTCAAGTTTTCTAGGGCCTTAAGAGTTTTAGAAATGTAATTCCCTTAGGAAAATGATGAGGTGATTTTTGAAA
Associated Phenotype:
Not determined