Busch Lab

ZMP

lyn

Ensembl ID:
ENSDARG00000031715
ZFIN ID:
ZDB-GENE-040912-7
Description:
tyrosine-protein kinase Lyn [Source:RefSeq peptide;Acc:NP_001004543]
Human Orthologue:
LYN
Human Description:
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog [Source:HGNC Symbol;Acc:6735]
Mouse Orthologue:
Lyn
Mouse Description:
Yamaguchi sarcoma viral (v-yes-1) oncogene homolog Gene [Source:MGI Symbol;Acc:MGI:96892]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa39845 Nonsense Mutation detected in F1 DNA Not yet available
sa19779 Nonsense Available for shipment Available now
sa14305 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa39845
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040555 Nonsense 108 510 5 13
Genomic Location (Zv9):
Chromosome 2 (position 27750115)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 27946311
GRCz11 2 27601945
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTCCAGGCATGGCGAGTGGTGGAAAGCGAGGTCTTTGACCACACGAAAA[G/T]AAGGTTTCATTCCCTCAAACTATGTTGCAGAAGCAGACACTATGGAGACA
Long Flanking Sequence:
TAAAAAAAAATAAAAATAAATAAATCATCTTAAGATTAATTTAGCAGATTTTACCTTCATCAAACTTGAAGAGAAAGGCTTTCTGATATATTTAAAACAATTTCATGATTGTCTGATGATCGAGAAACATTGTGTTTCACAGACTTCCCAAAATGCCGGTCTCCTGCCTGGTCAGGTTTTCCAAAAAATGGAAGGTAGGTTTCAATCCCTTCATTTTGATCCTTTTGTAGCTTTGAAGTTCTTTGTAAATCTGCTTTTTCATTGTCTTGAAACAGAGAAGGAAAAAATCGTTGTCGCTTTATATCCATATGAAGCCATTCACGCTGATGATCTGGGCTTTAAAAAAGGAGAGAAGTTAAAAATTATTGAGGAGTAAGTAAAAGCCATCATCATCCTTTGAGTGTCCTGCAGTATTTTGTTCGTTGGCTGTTATTGTGATGTGTGATTTATTTTCCAGGCATGGCGAGTGGTGGAAAGCGAGGTCTTTGACCACACGAAAA[G/T]AAGGTTTCATTCCCTCAAACTATGTTGCAGAAGCAGACACTATGGAGACAGAAGAGTGAGTGCGATCAATTACAAGCTTAAGGGATTAGTTCACCCTCAAATGAAAATTCAGTCATTAATGACTCGCCCTCATGTCATTCCAAACCCCTGAGACCTTCATTCATCTTCAGACACAAATTAAGGTATTTAGATGAAATCTGAGAGCTCCCTCATCCTCCATTGACAGCAAATTCCACAGAAGGAACAAAAATTATTTTCAAACCAACTTCAGCAGTTAAACTGTATTTACACAAAGCTCCAAGAACACTTTTTGTGGGACAGAAAAACTGTTTTCGCCTATGTCATCCGCATCAGATACAATGCTTATGGCCCAAGAAAATCTAAAGGCCCCTAAAAAAAACACCTAAGCATAAAATATACCTATAAATTATATAAACATAATTTTCCATCACTTTTTGTGTGATGAGGGTCTAAAAAAAGTTTTTATATAAAAAAATAGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19779
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040555 Nonsense 182 510 7 13
Genomic Location (Zv9):
Chromosome 2 (position 27745698)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 27941894
GRCz11 2 27597528
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATCGATCAGAGACGTAGACGCTCAGGGCCAGGATGTTGTTAAACATTAT[A/T]AGATCAGATCTCTGGATAATGGCGGTTACTACATCTCCCCAAAGATCACG
Long Flanking Sequence:
ATGTTACACACATATTGTTTGCTTTAAAAGCTTTAAGGCTCATTATTTTAAAATCATTCAGTAATGAAATGTTTATTAGTTGATGAAATCTATTAGTTTTTTTTAAAGTAACTTATCCAACATTGGTAATTAATAACATAATTAGTTTTCATATTTGGGTGAGCTAATCTTTTAGTAATAACATATTTCTTCATGCTTGCACATGTTTTCATTGTTGGTATGTTCTGATTTATCCTGCACAATTTAGATGGTTCTATAAAGACATCACGAGAAAGGATGCAGAGAGACAGCTGTTGGCACCGGCTAATAAACCTGGATCTTACCTCATACGGGAGAGCGAAACCTCAAAAGGTGATTACTATTTGCTGTCTGAACTCAAAGAGAGTTTGTGGTTAATCAAAATAGTGGTTTAACGTTTTTCTGCATTGTTGTGAACAGGAAGTTATTCACTATCGATCAGAGACGTAGACGCTCAGGGCCAGGATGTTGTTAAACATTAT[A/T]AGATCAGATCTCTGGATAATGGCGGTTACTACATCTCCCCAAAGATCACGTTCAGTGACATCAGCAGCATGATAAAACATTACCACAGTAAGTACTAAGGATGCAAACATTTTAGAGTTATTTAGAATACTGACCTTGTGTATAGTATAGCTATTGAACGTAGTAAAAAAGTGGTTCACCCAAGAATTTAGACGTTATTTAGAATACTGATGTGATTTACAGTATGTTAATTGATTGTATTAAAGGAGTGGTTTATCCAAAAATGAAAATTGCCTAATCATTTATTCTCCCTTGTATGATTTTGAACCTTTATGATATTTTTTACTCTGTTGAGCACAAAAGAAGATATTTTTAAAAATGATGTTGCACACATTGACTTCAATAGTAGGAAAAACACTACTGGAGGTTAATGAGTGCCAGCTACCAGCATTCTAAATATCTTCTTTTGTGTTAAACAGAAGGAAACAATTGGTGAAGAATGAGTAAATGATAGCAGAATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14305
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040555 Nonsense 329 510 10 13
Genomic Location (Zv9):
Chromosome 2 (position 27735607)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 27931803
GRCz11 2 27587437
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACTTTAACAGWATTTCGTTTATTCTTTTGCAGGAAGCTTATTGGATTTCT[T/A]GAAAAGTCAAGCTGGCTCCAAAATACAGTTACCAAAGTTGATAGATTTTT
Long Flanking Sequence:
TTTGCTTTTTGCTTTTTGTTTTATTTTATTAACCCTGAAAACAAAATGAGACATCTTGAGGATGACGATTTATTTTTAATAATTAAAAAATGATAATTACTTTTTACAGTTTACATATGATATATAATTTATCATACACTCTCAGTAATAAAGGTACGCGAGCTGTCACTGGGGTAATACCTTTTTAAAAGGTATACATTTGTACTTAAAGGGTCCATAATGGTACCTCAAAAGTATAAATTAGTACCTTAAATGTTTAGAGGAAAATTTTTGTACTTTTAAGGTACTAAAATGTACCCTTGATGTATTATTTATGGATCTTTTAAGGTACAAATTTGTACCCTTTGAAAAGGTACCACCCCAGTTACAGCTCGCGTACCTTTATTTCTGAGAGTGTATGTATTATAATTAAAGAAAAGTGTAGTTTAGTGAAAAGTTGTACCCTCAGTGACTTTAACAGTATTTCGTTTATTCTTTTGCAGGAAGCTTATTGGATTTCT[T/A]GAAAAGTCAAGCTGGCTCCAAAATACAGTTACCAAAGTTGATAGATTTTTCTGCACAGGTATAAAGAAAGTTTAAAACATGAATTATTCTTCTTTTCTCAAGCCCATCATTTCCTTATTTCTGAGGTTACTTTAAGGCTTTATTGCATCATCAAAGGCTGATCTCACTTTTTCCATTAAAAAAGAGGAACTGATACTAGTTTCAGTAGGCGGTTCAAAGCACAGAACAATATTCATTTTACTAGGAATGAAACATTTAATTTGATCTGTAAATAAAACTTTAAATGTGTGTTCTAAAAAGAGGTGGAAACCTAAATAAATCTTGAAACTTATATTGATAAATTGAATAAATGAAAAGATATGTCTTGTTAAAATGGTATGGACTTCAGACAGTATTTACCATCCTATACGATTAGATTCAAAACCAGTCGCTGATTTAAAAGCATTTGTTTGCTAAATGAGTCTTTTGGACTTCATTTGAGTTTGGCTTCTTGTAAAACA
Associated Phenotype:
Not determined