Busch Lab

ZMP

rab6bb

Ensembl ID:
ENSDARG00000031343
ZFIN ID:
ZDB-GENE-050320-28
Description:
RAB6B, member RAS oncogene family [Source:RefSeq peptide;Acc:NP_001013485]
Human Orthologue:
RAB6B
Human Description:
RAB6B, member RAS oncogene family [Source:HGNC Symbol;Acc:14902]
Mouse Orthologue:
Rab6b
Mouse Description:
RAB6B, member RAS oncogene family Gene [Source:MGI Symbol;Acc:MGI:107283]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa8400 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa25107 Nonsense Mutation detected in F1 DNA Not yet available
sa10297 Essential Splice Site Available for shipment Available now
sa19736 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa8400
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042255 Essential Splice Site 24 208 2 8

The following transcripts of ENSDARG00000031343 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 22255777)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 23142482
GRCz11 2 22798133
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TAGTCACTTCAGTGCATGTGATTTCCTGTTTTGTGTTGGTTTATTTTACA[G/A]TTGGGAAGACATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAAC
Long Flanking Sequence:
GGTTGACGTCAGCACCCAACGTCAGGCCGACGTCAATGTCCAACGTCCAACCTAAAATCAACCAAAAATCAACCAAATATCAACGTCTAATCATGTTACACCTTGATGTTGGGTGGATGTTACCACTATGACATCTATCAGACGCTGGATTTTGGTCACTTTCCAACACAACCTAAAATTAACCAAATATCAACGTTATTTGACGTCAAAATAACGTTGTCCTTAGACGCTGGTTAGACGTTGAATTTTGGTTACCTGACACAATCTAAATCTAACCTAATAATAACGTCTTATGATGTTTTGTGCCTGCTGGGTTTATTCATCAAGTCCCAACTTATCAAGCATTTGTTTTACCTAGCGGTTGCCCTTCCAGCTGCAACCCAGTACTAGGAAAATTAATTCAATGACTAGATTTTAATGTTTAGGGTTGTGTCAGGACAAACAAGTCATTAGTCACTTCAGTGCATGTGATTTCCTGTTTTGTGTTGGTTTATTTTACA[G/A]TTGGGAAGACATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAACACTTATCAGGTATAATATTGTATTTCAGTGCAGACGCTATATAGTTTTTCAGCTATGATTGTTCATGTTTTAATCTTACTATCAATCGCTTTACCATCACAGGCAACTATTGGCATTGACTTTTTATCAAAAACCATGTATCTGGAGGACCGAACTGTAAGAAGCCCTTTAACTAATTATATTCAGCTGCATTTTGTTTAGTTTACATTACATGTCCGCAGTTATTATAATGTCTTGTGTATTTTTGCAGGTGAGGTTACAGCTATGGGACACTGCAGGGCAGGAGCGTTTTAGGAGTCTTATCCCGAGCTACATTAGAGACTCCACAGTGGCTGTGGTGGTGTATGATATCACAAGTAAGCCACACACACACACACACACACACACAAACATACACACACACACACACACACACACACACACACACACACACACACACACACACACACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25107
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042255 Nonsense 42 208 2 8

The following transcripts of ENSDARG00000031343 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 22255833)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 23142538
GRCz11 2 22798189
KASP Assay ID:
554-7478.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGACATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAACACTTA[T/A]CAGGTATAATATTGTATTTCAGTGCAGACGCTATATAGTTTTTCAGCTAT
Long Flanking Sequence:
ATCAACCAAAAATCAACCAAATATCAACGTCTAATCATGTTACACCTTGATGTTGGGTGGATGTTACCACTATGACATCTATCAGACGCTGGATTTTGGTCACTTTCCAACACAACCTAAAATTAACCAAATATCAACGTTATTTGACGTCAAAATAACGTTGTCCTTAGACGCTGGTTAGACGTTGAATTTTGGTTACCTGACACAATCTAAATCTAACCTAATAATAACGTCTTATGATGTTTTGTGCCTGCTGGGTTTATTCATCAAGTCCCAACTTATCAAGCATTTGTTTTACCTAGCGGTTGCCCTTCCAGCTGCAACCCAGTACTAGGAAAATTAATTCAATGACTAGATTTTAATGTTTAGGGTTGTGTCAGGACAAACAAGTCATTAGTCACTTCAGTGCATGTGATTTCCTGTTTTGTGTTGGTTTATTTTACAGTTGGGAAGACATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAACACTTA[T/A]CAGGTATAATATTGTATTTCAGTGCAGACGCTATATAGTTTTTCAGCTATGATTGTTCATGTTTTAATCTTACTATCAATCGCTTTACCATCACAGGCAACTATTGGCATTGACTTTTTATCAAAAACCATGTATCTGGAGGACCGAACTGTAAGAAGCCCTTTAACTAATTATATTCAGCTGCATTTTGTTTAGTTTACATTACATGTCCGCAGTTATTATAATGTCTTGTGTATTTTTGCAGGTGAGGTTACAGCTATGGGACACTGCAGGGCAGGAGCGTTTTAGGAGTCTTATCCCGAGCTACATTAGAGACTCCACAGTGGCTGTGGTGGTGTATGATATCACAAGTAAGCCACACACACACACACACACACACACAAACATACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACATACAGCTTTCATGTTTCAGTTATGGAAATGTGCATTTAACAAAGCG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa10297
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042255 Essential Splice Site 43 208 2 8

The following transcripts of ENSDARG00000031343 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 22255837)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 23142542
GRCz11 2 22798193
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAACACTTATCAG[G/T]TATAATATTGTATTTCAGTGMAGACGCTATATAGTTTTTCAGMTATGATT
Long Flanking Sequence:
ACCAAAAATCAACCAAATATCAACGTCTAATCATGTTACACCTTGATGTTGGGTGGATGTTACCACTATGACATCTATCAGACGCTGGATTTTGGTCACTTTCCAACACAACCTAAAATTAACCAAATATCAACGTTATTTGACGTCAAAATAACGTTGTCCTTAGACGCTGGTTAGACGTTGAATTTTGGTTACCTGACACAATCTAAATCTAACCTAATAATAACGTCTTATGATGTTTTGTGCCTGCTGGGTTTATTCATCAAGTCCCAACTTATCAAGCATTTGTTTTACCTAGCGGTTGCCCTTCCAGCTGCAACCCAGTACTAGGAAAATTAATTCAATGACTAGATTTTAATGTTTAGGGTTGTGTCAGGACAAACAAGTCATTAGTCACTTCAGTGCATGTGATTTCCTGTTTTGTGTTGGTTTATTTTACAGTTGGGAAGACATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAACACTTATCAG[G/T]TATAATATTGTATTTCAGTGCAGACGCTATATAGTTTTTCAGCTATGATTGTTCATGTTTTAATCTTACTATCAATCGCTTTACCATCACAGGCAACTATTGGCATTGACTTTTTATCAAAAACCATGTATCTGGAGGACCGAACTGTAAGAAGCCCTTTAACTAATTATATTCAGCTGCATTTTGTTTAGTTTACATTACATGTCCGCAGTTATTATAATGTCTTGTGTATTTTTGCAGGTGAGGTTACAGCTATGGGACACTGCAGGGCAGGAGCGTTTTAGGAGTCTTATCCCGAGCTACATTAGAGACTCCACAGTGGCTGTGGTGGTGTATGATATCACAAGTAAGCCACACACACACACACACACACACACAAACATACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACATACAGCTTTCATGTTTCAGTTATGGAAATGTGCATTTAACAAAGCGCCTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19736
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000042255 Essential Splice Site 44 208 None 8

The following transcripts of ENSDARG00000031343 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 22255928)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 23142633
GRCz11 2 22798284
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGCTATGATTGTTCATGTTTTAATCTTACTATCAATCGCTTTACCATCAC[A/G]GGCAACTATTGGCATTGACTTTTTATCAAAAACCATGTATCTGGAGGACC
Long Flanking Sequence:
TTGGTCACTTTCCAACACAACCTAAAATTAACCAAATATCAACGTTATTTGACGTCAAAATAACGTTGTCCTTAGACGCTGGTTAGACGTTGAATTTTGGTTACCTGACACAATCTAAATCTAACCTAATAATAACGTCTTATGATGTTTTGTGCCTGCTGGGTTTATTCATCAAGTCCCAACTTATCAAGCATTTGTTTTACCTAGCGGTTGCCCTTCCAGCTGCAACCCAGTACTAGGAAAATTAATTCAATGACTAGATTTTAATGTTTAGGGTTGTGTCAGGACAAACAAGTCATTAGTCACTTCAGTGCATGTGATTTCCTGTTTTGTGTTGGTTTATTTTACAGTTGGGAAGACATCGCTGATAACAAGGTTCATGTATGACAGTTTTGACAACACTTATCAGGTATAATATTGTATTTCAGTGCAGACGCTATATAGTTTTTCAGCTATGATTGTTCATGTTTTAATCTTACTATCAATCGCTTTACCATCAC[A/G]GGCAACTATTGGCATTGACTTTTTATCAAAAACCATGTATCTGGAGGACCGAACTGTAAGAAGCCCTTTAACTAATTATATTCAGCTGCATTTTGTTTAGTTTACATTACATGTCCGCAGTTATTATAATGTCTTGTGTATTTTTGCAGGTGAGGTTACAGCTATGGGACACTGCAGGGCAGGAGCGTTTTAGGAGTCTTATCCCGAGCTACATTAGAGACTCCACAGTGGCTGTGGTGGTGTATGATATCACAAGTAAGCCACACACACACACACACACACACACAAACATACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACATACAGCTTTCATGTTTCAGTTATGGAAATGTGCATTTAACAAAGCGCCTCAGGCTCCAATTAGAGTAAGATTTTTCCTTCTCTTCCCCAGATATCAATTCATTCCAGCTAACCTCTAAATGGATTGATGATGTCAGAACAG
Associated Phenotype:
Not determined