Busch Lab

ZMP

melk

Ensembl ID:
ENSDARG00000030759
ZFIN IDs:
ZDB-GENE-990603-5, ZDB-GENE-990603-5
Description:
maternal embryonic leucine zipper kinase [Source:RefSeq peptide;Acc:NP_996771]
Human Orthologue:
MELK
Human Description:
maternal embryonic leucine zipper kinase [Source:HGNC Symbol;Acc:16870]
Mouse Orthologue:
Melk
Mouse Description:
maternal embryonic leucine zipper kinase Gene [Source:MGI Symbol;Acc:MGI:106924]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa19483 Nonsense Available for shipment Available now
sa11312 Nonsense Available for shipment Available now
sa14613 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa19483
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047728 Nonsense 130 676 5 18
ENSDART00000125259 Nonsense 130 676 4 17
Genomic Location (Zv9):
Chromosome 1 (position 20714933)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 21187029
GRCz11 1 21879966
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTTCGCCAGATCATCTCTGCGTTGGCCTATGTTCATAGCCAAGGTTA[T/A]GCCCATCGAGACCTCAAACCTGTGAGTTTGTCTTTGAAAAAGGGTTGTCG
Long Flanking Sequence:
AAAAAGATCTTGGGGTTTGTTATTCATTTTAAATGCCTTTACCATGAATCACAACATTTGAATGAGTACCTTAATAATTACGAAGGAAGTTATTTCTGAATTTATTCCTGATATTGAGATTTAATTTACTTTTGAAATTCAGAATAGTGTCTTTCAAGTGTTTATGTTACTAGGATGATCTGCCCAGAGTAAAGATAGAGATTGAGGCAATGAAGAACCTCAGTCATCAACATGTATGTCGTCTCTACCATGTCATTGAGACCACAAGCAAAATCTACATGGTGCTTGAGGTATGCTTTGCTGAATGTGGTTCTGATGTTTAAGGAATACCTATTAATCTTCATATGTTTAACTGCATGTATCTTGTCAATCTATCAGTACTGTCCTGGAGGAGAACTCTTTGATTACATCATTGCTAAAGATCGGTTATCAGAGGAAGAGACCCGAGTGTTTTTTCGCCAGATCATCTCTGCGTTGGCCTATGTTCATAGCCAAGGTTA[T/A]GCCCATCGAGACCTCAAACCTGTGAGTTTGTCTTTGAAAAAGGGTTGTCGACTCTGAATTAAAAATTGCCTTCACTATCTAGACAGGTGCCGGTATTGTGAGTACTGCACTAAAATATATTCTTTTTAAATGTCTGGGTAAAAAACCAACAACCTTTTTCCACTTTGACCACAAAATATTTTATTTTGAGAAACATTTAAAATATTTTGGATCTGTAAACATGTCAGCCTAAATAATTCAAGTCAATCATTGATTTCTGCTGTTGTCATTTGTTTTAAATTTGTTGAAATTTGTTTCTGCTGTTGTCATTTGTTTCAAAAACAGATTTCTTTACCATTTAAAATGGAATCTTTGGATATCTTTTCTGCTGCAGATACTGTTCTCATAAAAAAATTGAAACGTAAATAAAAACAATCTTACACATACCTTAGGAATGGTATAGCAGAAAAATTTGGCGGTGTTAAAACCCTGAGTTTTCCAAACTGCAGTATACCTTAAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11312
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047728 Nonsense 269 676 10 18
ENSDART00000125259 Nonsense 269 676 9 17
Genomic Location (Zv9):
Chromosome 1 (position 20710545)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 21182641
GRCz11 1 21875578
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CGTTTGACAKTGAAACATTTGCTTGATCACCCATGGGTTATGAGGGGCTA[C/A]AGCACACCAGTGGAGTGGCACAGTAAATATCCAGTAAGATCAGCTCTATT
Long Flanking Sequence:
CATCGATTGCGTGTGTGTTTCAGGCTGATGTTTGGAGTATGGGTGTATTGCTTTATGCACTACTGTGTGGTTTTCTACCATTTGATGATGACAATTGTATGGTTCTCTATAGAAAAATCACAGTAAGTCTATTCATGCTGCATAACTTGTGAGTAGCATTTAAACACACATAAATACACATTTTGTTGATCTACACATTTCTTAGCTTACTGGAATAAAAAAAAAGTTGTCTTGTGTAAATGTGTGATCGTATGTCATATAAAATTGGCTTATGTTTTGACAGAGAGGCAAATACAGCAACCCACACTGGCTTTCGCCTTCTAGTATTCTGCTTCTAAACCAAATGATGCAGGTAGTGTGTATGGTTTGTGTGTGTTTTTGTGTGTGTTTGATGTGTTTTATAAAGCAATGACAGTTTATTTTGTTCTCCTGCAGGTGGACCCAAAGAGGCGTTTGACAGTGAAACATTTGCTTGATCACCCATGGGTTATGAGGGGCTA[C/A]AGCACACCAGTGGAGTGGCACAGTAAATATCCAGTAAGATCAGCTCTATTTACATGCTTATAGTCACATCATATGCTTCCATGACTCCAGTAGTGGAAGTGGGCTTTTGAGCCTAATGGCACAATATGTAAGATGACTTTCATCAAAATATGCAAACCATATTGAAGTATATACTTGTAAAATCTCAAATGCTTCAAGGAATATTTAATTCCAGATAAATAATTTTTACTTTTAACAATATATATTTTTATTTTAAATGTTACGCACTCGATGTCTGTTTGGTTAGTAGACTACACAGAGCAGCTTTATAACAGAACCCTTAAATGTTTGTATCGTAAAAAAACAGCGCTGCTTCTTTCCTATGGGATCATGACCAGAAGAACTGTCTGAGGTTAACTGTGGAATAATAAAAGCTGTGCTGCTTTTGTGTCTTATCAGCAATTGTTTCAGCGCACTCGTTTCAATTTGACAGCTTTCACCCTTACTCTGCAACATACTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14613
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000047728 Nonsense 298 676 11 18
ENSDART00000125259 Nonsense 298 676 10 17
Genomic Location (Zv9):
Chromosome 1 (position 20709571)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 21181667
GRCz11 1 21874604
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGGGTCATATAGATGAAGACTGCATCACAGAAATGGCGGTGACTTWCAAA[C/T]AGTCCAAACAACGAACTATCCAGCTTGTGTCTGAGGTAGAGGAATTTAAT
Long Flanking Sequence:
TTTCACCCTTACTCTGCAACATACTTCCACGATAATAAGTCTTGAATACTTTAGTTCATGCATGAACATGATTTCTCCAGTAGTACTTTAGAATGTAATATAGAGCACAAGTTCCATTATCTCACACCAAACAATGCCTTTGTTTGTTGTGAATATGTGGTGAAAATTACATGTTGTGCCTTCAAAAACTGTTATGATAATATAGTGGTTACTTAATAAATTCTATCTGCTTTAGTTGTTGTAATGAATCTGCATGTCTTCAGTATTTTAGGTCCAATAGATTTAATATAATATAGTCCTCCTTTTGAACAAAGATGATGCATTTATTTTTCAGCAGAGCTCATTGTTTCTTCATAGATGCACATTCATAATGTATTTTAATCATATCTTAGCTTAGCTTTCTTAGCTTGTGTGTTGTTCAATTAATTATAGCATGTGTTTCTTTTTAGTTGGGTCATATAGATGAAGACTGCATCACAGAAATGGCGGTGACTTTCAAA[C/T]AGTCCAAACAACGAACTATCCAGCTTGTGTCTGAGGTAGAGGAATTTAATATTATTGATGAATTCTAGTTTCCCAGTGATTAGTTGCGGCTGGAAGGGCATCCGCTGCGTGAAAGCATATGCTGGATAAGTTGGCGGTTCATTCCGCTGTGGCGACCCCAGGTTAATAAAGGGACTTAGCCAAAAAGAAAACGAATGAATGATGAATTCTAATCAGTGGTATATTTATTATTAACAAAATGTATGTTTTTTTTAAGGAATTCAATTTCCAAAATGCATTTATTGGGGCAAAAATACAGTGAATACTGTAAAATATGGTTACATTTCAAAATATCTTTTTTCTTTAAATATGCTTTAATAGGGTTTCTGCAGATGCTAATCTTACCTTTGTATTTAGCAGACACACTTGTCAAAAGCATCCTACAGTAAGAGAAGGCAGCAAGTAATTCATAATTAAAAAGCATAAAATGTTAAAATACACAGTTTATAAATCTGCTAGAA
Associated Phenotype:
Not determined