Busch Lab

ZMP

dnmt1

Ensembl ID:
ENSDARG00000030756
ZFIN IDs:
ZDB-GENE-990714-15, ZDB-GENE-990714-15, ZDB-GENE-990714-15
Description:
DNA (cytosine-5)-methyltransferase 1 [Source:RefSeq peptide;Acc:NP_571264]
Human Orthologue:
DNMT1
Human Description:
DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:2976]
Mouse Orthologue:
Dnmt1
Mouse Description:
DNA methyltransferase (cytosine-5) 1 Gene [Source:MGI Symbol;Acc:MGI:94912]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa40174 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa40173 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa16282 Essential Splice Site Available for shipment Available now
sa40172 Nonsense Mutation detected in F1 DNA Not yet available
sa20150 Nonsense Available for shipment Available now
sa40171 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa40174
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021977 Essential Splice Site 227 1500 8 34
ENSDART00000078973 Essential Splice Site 227 1499 8 36
ENSDART00000128041 None None 200 None 9
Genomic Location (Zv9):
Chromosome 3 (position 55454620)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54348346
GRCz11 3 54602948
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAG[G/A]TGACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTA
Long Flanking Sequence:
ACGATTTTACTTTAGAGTTGGTGTACTTTTTTTAAATTGTGCAGATTTTGTTAATTTGCAGTCTGATATGGTAGTTTTGTGATCAAGATGTATGAATAAATTTTTATTATCATTTTTTTTTTTTTGTTAAATAATTGGGCCTTTATTCTTTCTTTTAATAGCCCAAAACGAAAGTCTGATGAGCTGAATGGAGAACCAGCAAATGGTGACACAGAAATTAAGACTGAGGAAACTATCACTGAGGAGGTCAGGTCGTTTTACAATTCATTGTTATTAAATTCATAAAAATTAATTTAACAGTATATTATTTTGGGGTTTTCAAGGTCCGTGAAGAGAAACGCCTTAAAACAGAAGATGAGAAGTGAGTATAGTGATGTAAAAGTAAAACTTGAAAACAGCCATTTTACAAATGTACTATGAGGTTTATGATCCCTTGTTGTTCCTCTCTCAGGCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAG[G/A]TGACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTAAACAACATCTTTAACTTGTTTTAGACTCCTCCGCCGAAATGTCCTGACTGCAGGCAGTATCTGGATGATTCAGACCTAAAGTTCTTTCAAGGGGATCCTGATGATGCTGTGAGCTTCCTACACCTATTTTTTTTTTTTTTTAAACCTTAATCTCAAATTAAGTTTTGTATAGGTTAAGTTTTTGTAGTGGCTGTACACTTGAATGATATGTTTGATTTTGTCTATGGTAGTTGGATGAACCAGAGATGTTAACCGATGAGCGTCTCTCCCTCTTTGATTCAAATGAGGATGGTTTTGAAAGCTATGAAGATCTTCCTCAGCACAAGATCACGAACTTCAGGTAAAGAAGAGATGGATGACTCCAAACTGATCAATGTTTTACTTGCCCACCCCCCACTAATGACTTTGCATCACCTCTCGTTTGTAGTGTGTATGACAAGCGTGGTCATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40173
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021977 Essential Splice Site 227 1500 8 34
ENSDART00000078973 Essential Splice Site 227 1499 8 36
ENSDART00000128041 None None 200 None 9
Genomic Location (Zv9):
Chromosome 3 (position 55454619)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54348345
GRCz11 3 54602947
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAGG[T/C]GACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTAA
Long Flanking Sequence:
CGATTTTACTTTAGAGTTGGTGTACTTTTTTTAAATTGTGCAGATTTTGTTAATTTGCAGTCTGATATGGTAGTTTTGTGATCAAGATGTATGAATAAATTTTTATTATCATTTTTTTTTTTTTGTTAAATAATTGGGCCTTTATTCTTTCTTTTAATAGCCCAAAACGAAAGTCTGATGAGCTGAATGGAGAACCAGCAAATGGTGACACAGAAATTAAGACTGAGGAAACTATCACTGAGGAGGTCAGGTCGTTTTACAATTCATTGTTATTAAATTCATAAAAATTAATTTAACAGTATATTATTTTGGGGTTTTCAAGGTCCGTGAAGAGAAACGCCTTAAAACAGAAGATGAGAAGTGAGTATAGTGATGTAAAAGTAAAACTTGAAAACAGCCATTTTACAAATGTACTATGAGGTTTATGATCCCTTGTTGTTCCTCTCTCAGGCCTGAAGCTGAGAATGCTGCTAACCTCAAACCTGTGTCTACAGCAAAGG[T/C]GACGCTTCTTTTCACTTCCAATTTGATTTGCCACTTGAATTAATAACTAAACAACATCTTTAACTTGTTTTAGACTCCTCCGCCGAAATGTCCTGACTGCAGGCAGTATCTGGATGATTCAGACCTAAAGTTCTTTCAAGGGGATCCTGATGATGCTGTGAGCTTCCTACACCTATTTTTTTTTTTTTTTAAACCTTAATCTCAAATTAAGTTTTGTATAGGTTAAGTTTTTGTAGTGGCTGTACACTTGAATGATATGTTTGATTTTGTCTATGGTAGTTGGATGAACCAGAGATGTTAACCGATGAGCGTCTCTCCCTCTTTGATTCAAATGAGGATGGTTTTGAAAGCTATGAAGATCTTCCTCAGCACAAGATCACGAACTTCAGGTAAAGAAGAGATGGATGACTCCAAACTGATCAATGTTTTACTTGCCCACCCCCCACTAATGACTTTGCATCACCTCTCGTTTGTAGTGTGTATGACAAGCGTGGTCATCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16282
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021977 Essential Splice Site 413 1500 13 34
ENSDART00000078973 Essential Splice Site 413 1499 13 36
ENSDART00000128041 None None 200 None 9
Genomic Location (Zv9):
Chromosome 3 (position 55453601)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54347327
GRCz11 3 54601929
KASP Assay ID:
2259-4164.1 (used for ordering genotyping assays)
KASP Sequence:
TCAGAAAAACCAGGATGCYACRTATGAGGACCTGCTGAACAAAATAGAGG[T/C]ACAMTTTATGGRAGYRTTGAAGTTCTTTGCCACTTGTCCYATTTTAGAAG
Long Flanking Sequence:
GCCTCATTGAGAAAAATGTGGAACTGTACTTTAGTTGTGCTGTAAAGCCCATCTATGATGACAACCCATGCATGGATGGTACGTGCCACTTTCATTACAATGAATACAGATGTTTTTTTATTTATTTATTTCAAATGCATTGTGTATTTGATTTCAAATTGTTCTCAGGTGGGGTTCCTGCCAAAAAGCTTGGTCCCATCAATGCTTGGTGGATCACTGGTTTTGATGGTGGGGAGAAGGCTTTGATTGGCTTCACTACAGGTATGTTTCAAAGCAAAGTTGACTCTTATCCTTGTCCAGTTTTATTATGCATGGCCATTTAACTAGTTTCATTTTCTTTTCGACAGCGTTTGCTGACTATATCCTAATGGACCCCAGTGAGGAGTACTCTGCTATTTTTGCTCTGATGCAGGAGAAGATCTACATGAGCAAAATTGTGGTTGAATTTCTTCAGAAAAACCAGGATGCCACATATGAGGACCTGCTGAACAAAATAGAGG[T/C]ACACTTTATGGGAGCATTGAAGTTCTTTGCCACTTGTCCCATTTTAGAAGTTGTGGGATAACCTGTTATTTGTCTTTTTAGACTACTGTCCCGCCCGCGGGGCTCAACTTCAACCGTTTCACAGAAGACACACTCTTGCGCCATGCCCAGTTTGTGGTAGAGCAGGTCGAGAGCTACGATGAGGCTGGAGACTCTGATGAACAACCCATTATAATCACTCCATGTATGCGTGACTTGATCAAGCTGGCTGGTGTTACTTTGGGCAAGAGGTGAGTTTACTAGAATTGGTGGTCTCTTAAATGCCTTCAATGAGATAACTGGGTAATGGTGGGTTCGATATACTGGTACCCAGAAAGCAGACCTCAAACTGTTCTCTTAGCAACTGAAACCAATTTGTTATTTTATCCTGCATGAGGCATGGGCTTCAATATTGTGGACCATCAGGGAGGGCTATCGGTGTTTCTCATAGGACATATAATGTATTCATGTAGCTTAAACCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40172
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021977 Nonsense 563 1500 16 34
ENSDART00000078973 Nonsense 563 1499 16 36
ENSDART00000128041 None None 200 None 9
Genomic Location (Zv9):
Chromosome 3 (position 55452192)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54345918
GRCz11 3 54600520
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTTCAGCTTGTAAGGATATGATCAAGTTTGGAGGCAGTGGCAGAAGTAAA[C/T]AAGCCTGTCAGAAGAGGAGGTATGCTTACTGTGCAGTCTTTGCTGTTGCG
Long Flanking Sequence:
TCTGAACATCTTTTTTCAGTTTAAATGGGTTTAGTTACTTCAGAGCTGTTTGTCTTAACTCAATCCATTGTGTCTTGTGCATTAAACGCATGGCTCTTTTTTGCTTTTATTTGTGCCCTCTGTATCTTGTTTGCTCTGCTCATGTTTTTTTTTTTTCCCCTGTTCAGGAGAGCAGCCAGAAGACAAGCCGTCCGCCATCCCACTAAGATTGAAAAGGACAACAAGGGCCCGACTAAAGCCACCACCACTAAACTGGTCTACCTGATCTTTGACACATTCTTCTCTGATCAGATTGACCAGAACAATAAGGATGGAGGTGTGAAGAGACAACGGTGTGGTGTCTGTGAGGTTGGTTGTCTGAAAATAGCAGGCACAGTTTAACTGAAATGCAAGCATGATGATTGGCGACCTTGGTATTTCAGGTGTGTCAAGCTCCAGACTGCGGCAAGTGTTCAGCTTGTAAGGATATGATCAAGTTTGGAGGCAGTGGCAGAAGTAAA[C/T]AAGCCTGTCAGAAGAGGAGGTATGCTTACTGTGCAGTCTTTGCTGTTGCGTAATCATTCTCCTCAGCAGTTTTGTATTTTCCATGTGTTTTAAAGGCCTTTCTTTGCTTTCTCTGTTTTTATATTATAATGATTAACATTTTGAATGAGGCTAAATGTCATTCAACAATTAAGGTTTTTAATAGTTTTTACTATTTATAGTGCCAATTTTGTCTATACTCATGCCATTTTAAATTGGCATTTCATTTACCTAGGCATGTATATTTAATTGATCTCAGATTAAATGTTACAATGATATCTAATTGTCTTAAACAACTTCCTAGTTGTTGACCTTTTAGGCCCCGTTTACACTAGTGCGTTTTAGTATTAAAACATCGTTTTAGAATGAAAACGATCCGCGTCCACACTCGCTTTTTACCCAGCGTTTCTGAACTGCTCTCCGTCCACACCAAAATTCTGAAAACGCACATCACATGACCACACACACACACACACACACAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa20150
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021977 Nonsense 698 1500 19 34
ENSDART00000078973 Nonsense 698 1499 19 36
ENSDART00000128041 None None 200 None 9
Genomic Location (Zv9):
Chromosome 3 (position 55449605)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54343331
GRCz11 3 54597933
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCCTTGGAGAGTCATCAGACCCTCTTGAGCTCTTCCTAGTGGATGAGTG[T/A]GAAGACATGCAGCTAAGTTTTATCCATGGCAAGGTCAACGTCTTCTACAA
Long Flanking Sequence:
TGTAGCTGGTAAACTCCTTTTTGTTTCATGGCTTTTGCTGTTTTTGCCTTAGTTTGTCAAGTTGTGCTACTAACCCTTTTAGCTTTCATGTGGCTGGAGACTTTTCTCCCCTCCCAAATTTAGAAGACTTTAAATTTTTATTTTTTTTTTGCCGTCATCTTTTCAGACTGAGGGAAAGAAGGAATATTACATGAAAGTGCGTGTGGAAAATGAGGTGTTGGAGGTGGGAGATTGTGTATCTGTAAGCCCTGATGACCCATCACATCCTCTCTACCTGGCCAGGTAAAATTATCAAAGCAATTTCTTTTGTAAAACCAAAAGGTTTAACATGTTTACTAGACTCTCTAATTAGTAAATCATTGGTTTCTTTAAATTTGTAGGATTACAGCTTTGTGGGATGATGGTGAGAAGATGTTTCATGCCCATTGGTTCTGCCGTGGCACTGATACGGTCCTTGGAGAGTCATCAGACCCTCTTGAGCTCTTCCTAGTGGATGAGTG[T/A]GAAGACATGCAGCTAAGTTTTATCCATGGCAAGGTCAACGTCTTCTACAAGGCACCATCTGAAAACTGGTATATGGAGGTACATACGCCAAAGTGTGGGCAGTGTTTGTGTTTAACAAACTGGGCAGAGGTTTTAACACTGTTATTGTTTTGAAGGGTGGAATGGATGAAGACATCAAAGTGATTGACGATGATGGTGAAAGCTTCTTTTATCAGCTCCATTATGAAGGTGAATGTGCTCGCTTTGAGACTCCTCCCAAGGTCACACCCTCTGAGGACTGCAAGTATAAGTAAGAGCCCCTTTTGACCTATTTTAATGGGACACCTGTTCTGTATTTGTGCTATAAAATGTTATGTTTCACTAGGTTTTGTGCCAGCTGCACCAGAAACAAAGAACGAGAGGCTGAGTCTGTTCCCCATGCCTATGAGCCCTTAGAGGATGAGGAGAGTGACTCTAAAGTCTTCTATGGGTTGGTGAACTATAAGGGAGAGCAGTACAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40171
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000021977 Nonsense 1016 1500 25 34
ENSDART00000078973 Nonsense 1015 1499 27 36
ENSDART00000128041 None None 200 None 9
Genomic Location (Zv9):
Chromosome 3 (position 55448044)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 54341770
GRCz11 3 54596372
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAGGGAAAGGGAAAGCAGCGCCTCAAGAACCACAGGATCAGGAGCCA[C/T]AAGAGCCAGTGGTTCCCAAACTGCGCACTCTGGATGTATTCTCTGGCTGT
Long Flanking Sequence:
CTGTCGTGTTGAGTATGCAGAGGATCTGGTTGAAAGTGTGCAGGACTATTCAAACAAAGGACCCGATCGCTTCTATTTCCTTGAGGTAAGGATAAAATCTGGCTGTAATGGAGCTGCCAATGGTACTCGTAATGCAGCTGAAAATATTTTCTGCCATGACTTACCTAATGGTTCTTTTTGTAGGCATACAATGCCAAAACCAAGAGCTTTGAGGATCCTCCCAATCATGCTAGATCTGCTGTGAATAAGGGCAAAGGGAAAGGAAAGGGCAAAGGTAAGTCAAGTGTAATGTTGAAATAAGTAATGGAAACTTCTAGGTATGCTCTTGTGTTTTTTTTAAGCTAAAAATGGTCCATCGTGGATTCAAGATGGCTTAAATATCTGAACACAATCATAACTGCATGTGGGGAGAAATTGCAGCTTAAATGTTTGTACCATGGTTGTCTGTAGGAAAAGGGAAAGGGAAAGCAGCGCCTCAAGAACCACAGGATCAGGAGCCA[C/T]AAGAGCCAGTGGTTCCCAAACTGCGCACTCTGGATGTATTCTCTGGCTGTGGTGGTCTGTCTGAGGGCTTCCATCAAGCAGGTTTGGCTTCCATTGAGTCTCTTTATAGAACCATGTTACACAATGTATTATTACTAGGGATGTAACTGTATTGTAAATACCGTCATACCGCAATATTAATTTTTTTTGATATTACCGAAGTCGCACGACTCAGTAAAACTATAGGTCTTCTGAGAAAATTTGCTCAGGCGAATGAAGCGAACGGGAGGTAGCGAAAACTACAATTCCCATCAGCCCATGCTTGACCATCATCCCTTGCGGTCTGTTGTCGCTACAGATCCAGTAATGCGGAAATAGAGTGTGCTGCTAGAAGCGGGGATGAAAAAAGAGCTGGAAAACTCTAAAGCGGGTGTTGTCGCCGCGTGCGTACTTAATAGCGGTGTTGTCGCGCGAGTTCTTATCAGCTGTGTTGTCGCGCGCGTACTGAATAGCGGTGTTGT
Associated Phenotype:
Not determined