Busch Lab

ZMP

ARHGEF12 (1 of 2)

Ensembl ID:
ENSDARG00000030532
Description:
Rho guanine nucleotide exchange factor (GEF) 12 [Source:HGNC Symbol;Acc:14193]
Human Orthologue:
ARHGEF12
Human Description:
Rho guanine nucleotide exchange factor (GEF) 12 [Source:HGNC Symbol;Acc:14193]
Mouse Orthologue:
Arhgef12
Mouse Description:
Rho guanine nucleotide exchange factor (GEF) 12 Gene [Source:MGI Symbol;Acc:MGI:1916882]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa10278 Nonsense Available for shipment Available now
sa17338 Essential Splice Site Available for shipment Available now
sa32031 Essential Splice Site Available for shipment Available now
sa35876 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa10278
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
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Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040542 Nonsense 524 1357 18 39
Genomic Location (Zv9):
Chromosome 15 (position 21469780)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 22572406
GRCz11 15 22508138
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGAAGCATCTGGGAGTTCGGGCGAAAGARCARCGAAACCTGGAATCCAAA[C/T]GAGTTCGAATTAATTTCCTTCCTTCCAAACTAAGGGTATGTGCCATTTCT
Long Flanking Sequence:
ACTTGACACAAATGCAAGATGCTGCCGAACAGAGCGACTTAATGAGATTTGTAATCCTCATGCATTTCCTAGTCCTCATTTACCATAATTTAGGCAAACATATTTGAGATGCCATATGGAAACACCACAAGCTTGTATGATTTATGAATGTACAGGACATATGCGAGAAGATAGATGGGGAAACTCGTGCACGTGTTTTGTGACATATGGCAGAAGGCACAATAAGATAGGAGTCATGTGGAACAGAAGGAGTCGACCACATGGAGCCAACAGCACTCAACATGCACAAGACAACCCTCTGAGACTCAAATCTAAATTAGGAAATGAAAGACTTCGATGCTCATCGCTGTGCTCTAGTTGGACAGAGAGTGAGGGAAGAGTTCAGTTTAGCCCTAAATCTGAGTTTGGTCTCTTCCAGCTCCACTATACAGTATGTGATCTTCATGTACATGAAGCATCTGGGAGTTCGGGCGAAAGAACAACGAAACCTGGAATCCAAA[C/T]GAGTTCGAATTAATTTCCTTCCTTCCAAACTAAGGGTATGTGCCATTTCTTGAAATGTTTTACGCAACCTAAAAGATATATCTTCCAAAAATGAATTGACTCAATATTTGAGCACAATAGAAGATATTTTGAAGATTGTTGGAAAGCGGTAGTTGTTAAAATCTGTAAAGGGGAAAACATAAAAAAGAAACCAATGACTTCAACATTTCTCAAAATATCTTTTTTGTGTTCAACAGAAGAAAGTAATTCAGGTTTGGACTAAGTAGAGGATGAGTAAATTACAGAATTTTAATTTTTTGGGTGTGCTGTCTCTTTAAGAGCTAGCATAATTACCACACAAATTATGTCTTGAAATGATGCCCTTATAAGCAGTTAACTAGGGTTTGGAACTGAGTAATTATCTTCAGTCTTACCATGGTAATGCTGTTACCCTGAGGATTGTTGTTTTATCCTTCCTGAACAGAAAAGCAAAACAGAAAAGGATGGGGAGGAGAAACTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17338
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
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Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040542 Essential Splice Site 698 1357 22 39
ENSDART00000040542 Essential Splice Site 698 1357 22 39
Genomic Location (Zv9):
Chromosome 15 (position 21475284)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 22577910
GRCz11 15 22513642
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/A]TAATGGTCACTGCTTCTGTCAATCACTCACAKCACTCTAAATACACCGTG
Long Flanking Sequence:
TAAAGAGCAACGAATGAATCTCTTAGTTATTTCGTTTTTTTTTTTATTACAATCAAATAACAGGTGTCACTTTAAAAATGCACACATCTAACATTATAATGAAAGCATTTGATTGGTTTTATAACATTTTATGCTAATTTAGGACAAAATTAGTTTGAAAAAACCCATCAAGATCACTGTCTTTAAATATTATTATTATTTATGTGTATATGTCCGTTTAAATACGCACCCAAAACTCAGAATAACTTAAAGGTTTAAGCATTATTGAAATATGGAATTATTGGAGTTTATTGTTTTACCAGTTGTTTATCAATTAATATATTACATTGCCTACTGTTTTAAACCAGGTAAATAGATAAAGTAAAATAAACAGTGTGTGATTTGTGCATACAATAAAACCAATACTATTGATTTAGCTGCTAATCTTAGCAAGCATCTGTGTACCGTTTTTTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/A]TAATGGTCACTGCTTCTGTCAATCACTCACATCACTCTAAATACACCGTGTCCTAACCAGAAGAGACTTGATAAAGTCACAGTCGATAAAAGCTATTTATTTCCTTCCTAACCAGCTGTGATGAGAACATTTGCTCTATTGCCTGTGCTTTCTGTTTTGTACCTGATCATATAAACTTGTATGTTTAAAGTGGTGACCTATATAAATGTATAATAAACATTAAATATTGTCTGATTGGGTCAGTTTAGTTTCATTTTTATTGCTTAACACTTGGTTGAAATACACCATTAAGCTCTTTTTTTAAGGAAACATTATGCAGCAAGTCTCATATTTAAATAGAGTTGCACATTTCGATTAATAGGAGCGTTAATCTATGTAGCATCTCCTCCCTCACAGGTTTGAGGATCTGCAGAGTGAGGATGATCAGGGGAGTGATGTTTACTCTGATGTAGATCCTCCAAACTGGCAGCAGCTGGTCGGGCGTGATGTTTTAGCAGGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32031
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040542 Essential Splice Site 698 1357 22 39
ENSDART00000040542 Essential Splice Site 698 1357 22 39
Genomic Location (Zv9):
Chromosome 15 (position 21475284)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 22577910
GRCz11 15 22513642
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/T]TAATGGTCACTGCTTCTGTCAATCACTCACATCACTCTAAATACACCGTG
Long Flanking Sequence:
TAAAGAGCAACGAATGAATCTCTTAGTTATTTCGTTTTTTTTTTTATTACAATCAAATAACAGGTGTCACTTTAAAAATGCACACATCTAACATTATAATGAAAGCATTTGATTGGTTTTATAACATTTTATGCTAATTTAGGACAAAATTAGTTTGAAAAAACCCATCAAGATCACTGTCTTTAAATATTATTATTATTTATGTGTATATGTCCGTTTAAATACGCACCCAAAACTCAGAATAACTTAAAGGTTTAAGCATTATTGAAATATGGAATTATTGGAGTTTATTGTTTTACCAGTTGTTTATCAATTAATATATTACATTGCCTACTGTTTTAAACCAGGTAAATAGATAAAGTAAAATAAACAGTGTGTGATTTGTGCATACAATAAAACCAATACTATTGATTTAGCTGCTAATCTTAGCAAGCATCTGTGTACCGTTTTTTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/T]TAATGGTCACTGCTTCTGTCAATCACTCACATCACTCTAAATACACCGTGTCCTAACCAGAAGAGACTTGATAAAGTCACAGTCGATAAAAGCTATTTATTTCCTTCCTAACCAGCTGTGATGAGAACATTTGCTCTATTGCCTGTGCTTTCTGTTTTGTACCTGATCATATAAACTTGTATGTTTAAAGTGGTGACCTATATAAATGTATAATAAACATTAAATATTGTCTGATTGGGTCAGTTTAGTTTCATTTTTATTGCTTAACACTTGGTTGAAATACACCATTAAGCTCTTTTTTTAAGGAAACATTATGCAGCAAGTCTCATATTTAAATAGAGTTGCACATTTCGATTAATAGGAGCGTTAATCTATGTAGCATCTCCTCCCTCACAGGTTTGAGGATCTGCAGAGTGAGGATGATCAGGGGAGTGATGTTTACTCTGATGTAGATCCTCCAAACTGGCAGCAGCTGGTCGGGCGTGATGTTTTAGCAGGCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35876
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000040542 Nonsense 828 1357 26 39
Genomic Location (Zv9):
Chromosome 15 (position 21478427)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 22581053
GRCz11 15 22516785
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACTCACCCATGTATCCTCTGGCTTGTTGTTTTCTAGTTCAGCAGTGGA[G/T]AGGAGGAGAAGATCAAGCAAGCAGTGGGCACTTTCTGCAGTAACCAGCCC
Long Flanking Sequence:
TTGGTTAGTTTTTTTTTTTTTATTCATCCAGTGTTTTGTATCCCCCAAATCCCTGTCTGTCTGATACTCTCAGAGCTGTTCTACACGGAGCGAGCTCACGTACGCATGTTGAAGGTCCTAGACAAGGTCTTCTACCAGAAACTCAACCGAGACAACATACTGCCCCCTGCTGACATCAAGTACATATTCACCAACCTGGAGGAAATCATCCAACTCCACGGTATGCTTTTTTTTTTTCTTCAAACTAACATTCATATAAATAATCCAAGCCACATGTCTCATGGCATCTGCTCTTTTAAATTTCAGTGAGAATAGTGGATCAAATGACAGCAATTTGCAAGAAGAACGAGACGTCTGTAATCGACCACATAGGAGACGAGTTGTTGTCTTGGGTAAGGGCTTTTGTTTTGCTGGTAAAATGTGGTGGGCCCTGTCTGGGTGATGAGACTCCCACTCACCCATGTATCCTCTGGCTTGTTGTTTTCTAGTTCAGCAGTGGA[G/T]AGGAGGAGAAGATCAAGCAAGCAGTGGGCACTTTCTGCAGTAACCAGCCCTTCGCCCTGGAGCTCATCAAATCCCGACAGAAGAAGGACCAACGTTTCTCCTCCTTCATGCAGGTGGGTTGATACTCCTTGCTCTGGCCATAGGGTAACCAGAGCTGCAGCGTCAGTTTTGTTCTATAATATGATGTAGGGCTGTTAATATTATTTTACTCTAGTCGAGACATCGCAAAAGTAAGAGATTCTAAAATAGAAACTTGAGCATCGTTGTCAGAGACGTTTAAAACAGAAACTTAATTTAAAATTAAAAATATACCTTTTCCTGTGTTGTGTCAAATTGTGTGTTATTAAAACAAAATATATGTAGCAACTGAGGAGGTTTGGTGTAAAGTAAAATATGAGGGATAGCCACAACAGTACCTTTACCTTATCATGAGTTTTTTTTTTATCGTTTCCTAACTGCAAAAGGCGTGTAAATTCTTCCATTTGTTTTGTGAAAACCGA
Associated Phenotype:
Not determined