ZMP
ARHGEF12 (1 of 2)
Ensembl ID:
Description:
Rho guanine nucleotide exchange factor (GEF) 12 [Source:HGNC Symbol;Acc:14193]
Human Orthologue:
ARHGEF12
Human Description:
Rho guanine nucleotide exchange factor (GEF) 12 [Source:HGNC Symbol;Acc:14193]
Mouse Orthologue:
Arhgef12
Mouse Description:
Rho guanine nucleotide exchange factor (GEF) 12 Gene [Source:MGI Symbol;Acc:MGI:1916882]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa6375 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa10278 | Nonsense | Available for shipment | Available now |
| sa17338 | Essential Splice Site | Available for shipment | Available now |
| sa32031 | Essential Splice Site | Available for shipment | Available now |
| sa35876 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa6375
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Founder:
SL4-81
KASP Assay Location:
Project 554.35, Plate 18, Well D12
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040542 | Nonsense | 506 | 1357 | 18 | 39 |
Genomic Location (Zv9):
Chromosome 15 (position 21469728)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 22572354 |
| GRCz11 | 15 | 22508086 |
KASP Assay ID:
554-5466.1 (used for ordering genotyping assays)
KASP Sequence:
CTGAGTTTGGTCTCTTCCAGCTCCACTATACAGTATGTGATCTTCATGTA[C/A]ATGAAGCATCTGGGAGTTCGGGCGAAAGARCARCGAAACCTGGAATCCAA
Long Flanking Sequence:
ATTGTGTCAGATTTGTTTGTAAATTGTTAGCTTGGGGTTCCAGCACATTGACACTTGACACAAATGCAAGATGCTGCCGAACAGAGCGACTTAATGAGATTTGTAATCCTCATGCATTTCCTAGTCCTCATTTACCATAATTTAGGCAAACATATTTGAGATGCCATATGGAAACACCACAAGCTTGTATGATTTATGAATGTACAGGACATATGCGAGAAGATAGATGGGGAAACTCGTGCACGTGTTTTGTGACATATGGCAGAAGGCACAATAAGATAGGAGTCATGTGGAACAGAAGGAGTCGACCACATGGAGCCAACAGCACTCAACATGCACAAGACAACCCTCTGAGACTCAAATCTAAATTAGGAAATGAAAGACTTCGATGCTCATCGCTGTGCTCTAGTTGGACAGAGAGTGAGGGAAGAGTTCAGTTTAGCCCTAAATCTGAGTTTGGTCTCTTCCAGCTCCACTATACAGTATGTGATCTTCATGTA[C/A]ATGAAGCATCTGGGAGTTCGGGCGAAAGAACAACGAAACCTGGAATCCAAACGAGTTCGAATTAATTTCCTTCCTTCCAAACTAAGGGTATGTGCCATTTCTTGAAATGTTTTACGCAACCTAAAAGATATATCTTCCAAAAATGAATTGACTCAATATTTGAGCACAATAGAAGATATTTTGAAGATTGTTGGAAAGCGGTAGTTGTTAAAATCTGTAAAGGGGAAAACATAAAAAAGAAACCAATGACTTCAACATTTCTCAAAATATCTTTTTTGTGTTCAACAGAAGAAAGTAATTCAGGTTTGGACTAAGTAGAGGATGAGTAAATTACAGAATTTTAATTTTTTGGGTGTGCTGTCTCTTTAAGAGCTAGCATAATTACCACACAAATTATGTCTTGAAATGATGCCCTTATAAGCAGTTAACTAGGGTTTGGAACTGAGTAATTATCTTCAGTCTTACCATGGTAATGCTGTTACCCTGAGGATTGTTGTTTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa10278
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Founder:
SL4_02_C11
KASP Assay Location:
Unknown
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040542 | Nonsense | 524 | 1357 | 18 | 39 |
Genomic Location (Zv9):
Chromosome 15 (position 21469780)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 22572406 |
| GRCz11 | 15 | 22508138 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGAAGCATCTGGGAGTTCGGGCGAAAGARCARCGAAACCTGGAATCCAAA[C/T]GAGTTCGAATTAATTTCCTTCCTTCCAAACTAAGGGTATGTGCCATTTCT
Long Flanking Sequence:
ACTTGACACAAATGCAAGATGCTGCCGAACAGAGCGACTTAATGAGATTTGTAATCCTCATGCATTTCCTAGTCCTCATTTACCATAATTTAGGCAAACATATTTGAGATGCCATATGGAAACACCACAAGCTTGTATGATTTATGAATGTACAGGACATATGCGAGAAGATAGATGGGGAAACTCGTGCACGTGTTTTGTGACATATGGCAGAAGGCACAATAAGATAGGAGTCATGTGGAACAGAAGGAGTCGACCACATGGAGCCAACAGCACTCAACATGCACAAGACAACCCTCTGAGACTCAAATCTAAATTAGGAAATGAAAGACTTCGATGCTCATCGCTGTGCTCTAGTTGGACAGAGAGTGAGGGAAGAGTTCAGTTTAGCCCTAAATCTGAGTTTGGTCTCTTCCAGCTCCACTATACAGTATGTGATCTTCATGTACATGAAGCATCTGGGAGTTCGGGCGAAAGAACAACGAAACCTGGAATCCAAA[C/T]GAGTTCGAATTAATTTCCTTCCTTCCAAACTAAGGGTATGTGCCATTTCTTGAAATGTTTTACGCAACCTAAAAGATATATCTTCCAAAAATGAATTGACTCAATATTTGAGCACAATAGAAGATATTTTGAAGATTGTTGGAAAGCGGTAGTTGTTAAAATCTGTAAAGGGGAAAACATAAAAAAGAAACCAATGACTTCAACATTTCTCAAAATATCTTTTTTGTGTTCAACAGAAGAAAGTAATTCAGGTTTGGACTAAGTAGAGGATGAGTAAATTACAGAATTTTAATTTTTTGGGTGTGCTGTCTCTTTAAGAGCTAGCATAATTACCACACAAATTATGTCTTGAAATGATGCCCTTATAAGCAGTTAACTAGGGTTTGGAACTGAGTAATTATCTTCAGTCTTACCATGGTAATGCTGTTACCCTGAGGATTGTTGTTTTATCCTTCCTGAACAGAAAAGCAAAACAGAAAAGGATGGGGAGGAGAAACTAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa17338
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Founder:
SL4_09_F12
KASP Assay Location:
Unknown
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040542 | Essential Splice Site | 698 | 1357 | 22 | 39 |
| ENSDART00000040542 | Essential Splice Site | 698 | 1357 | 22 | 39 |
Genomic Location (Zv9):
Chromosome 15 (position 21475284)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 22577910 |
| GRCz11 | 15 | 22513642 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/A]TAATGGTCACTGCTTCTGTCAATCACTCACAKCACTCTAAATACACCGTG
Long Flanking Sequence:
TAAAGAGCAACGAATGAATCTCTTAGTTATTTCGTTTTTTTTTTTATTACAATCAAATAACAGGTGTCACTTTAAAAATGCACACATCTAACATTATAATGAAAGCATTTGATTGGTTTTATAACATTTTATGCTAATTTAGGACAAAATTAGTTTGAAAAAACCCATCAAGATCACTGTCTTTAAATATTATTATTATTTATGTGTATATGTCCGTTTAAATACGCACCCAAAACTCAGAATAACTTAAAGGTTTAAGCATTATTGAAATATGGAATTATTGGAGTTTATTGTTTTACCAGTTGTTTATCAATTAATATATTACATTGCCTACTGTTTTAAACCAGGTAAATAGATAAAGTAAAATAAACAGTGTGTGATTTGTGCATACAATAAAACCAATACTATTGATTTAGCTGCTAATCTTAGCAAGCATCTGTGTACCGTTTTTTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/A]TAATGGTCACTGCTTCTGTCAATCACTCACATCACTCTAAATACACCGTGTCCTAACCAGAAGAGACTTGATAAAGTCACAGTCGATAAAAGCTATTTATTTCCTTCCTAACCAGCTGTGATGAGAACATTTGCTCTATTGCCTGTGCTTTCTGTTTTGTACCTGATCATATAAACTTGTATGTTTAAAGTGGTGACCTATATAAATGTATAATAAACATTAAATATTGTCTGATTGGGTCAGTTTAGTTTCATTTTTATTGCTTAACACTTGGTTGAAATACACCATTAAGCTCTTTTTTTAAGGAAACATTATGCAGCAAGTCTCATATTTAAATAGAGTTGCACATTTCGATTAATAGGAGCGTTAATCTATGTAGCATCTCCTCCCTCACAGGTTTGAGGATCTGCAGAGTGAGGATGATCAGGGGAGTGATGTTTACTCTGATGTAGATCCTCCAAACTGGCAGCAGCTGGTCGGGCGTGATGTTTTAGCAGGCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa32031
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Founder:
SL6_05_A2
KASP Assay Location:
Unknown
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040542 | Essential Splice Site | 698 | 1357 | 22 | 39 |
| ENSDART00000040542 | Essential Splice Site | 698 | 1357 | 22 | 39 |
Genomic Location (Zv9):
Chromosome 15 (position 21475284)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 22577910 |
| GRCz11 | 15 | 22513642 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/T]TAATGGTCACTGCTTCTGTCAATCACTCACATCACTCTAAATACACCGTG
Long Flanking Sequence:
TAAAGAGCAACGAATGAATCTCTTAGTTATTTCGTTTTTTTTTTTATTACAATCAAATAACAGGTGTCACTTTAAAAATGCACACATCTAACATTATAATGAAAGCATTTGATTGGTTTTATAACATTTTATGCTAATTTAGGACAAAATTAGTTTGAAAAAACCCATCAAGATCACTGTCTTTAAATATTATTATTATTTATGTGTATATGTCCGTTTAAATACGCACCCAAAACTCAGAATAACTTAAAGGTTTAAGCATTATTGAAATATGGAATTATTGGAGTTTATTGTTTTACCAGTTGTTTATCAATTAATATATTACATTGCCTACTGTTTTAAACCAGGTAAATAGATAAAGTAAAATAAACAGTGTGTGATTTGTGCATACAATAAAACCAATACTATTGATTTAGCTGCTAATCTTAGCAAGCATCTGTGTACCGTTTTTTTTTTTTTTTTAGACCTCCTGATGTGGGCACACCTAAACCGAGCAGAAG[G/T]TAATGGTCACTGCTTCTGTCAATCACTCACATCACTCTAAATACACCGTGTCCTAACCAGAAGAGACTTGATAAAGTCACAGTCGATAAAAGCTATTTATTTCCTTCCTAACCAGCTGTGATGAGAACATTTGCTCTATTGCCTGTGCTTTCTGTTTTGTACCTGATCATATAAACTTGTATGTTTAAAGTGGTGACCTATATAAATGTATAATAAACATTAAATATTGTCTGATTGGGTCAGTTTAGTTTCATTTTTATTGCTTAACACTTGGTTGAAATACACCATTAAGCTCTTTTTTTAAGGAAACATTATGCAGCAAGTCTCATATTTAAATAGAGTTGCACATTTCGATTAATAGGAGCGTTAATCTATGTAGCATCTCCTCCCTCACAGGTTTGAGGATCTGCAGAGTGAGGATGATCAGGGGAGTGATGTTTACTCTGATGTAGATCCTCCAAACTGGCAGCAGCTGGTCGGGCGTGATGTTTTAGCAGGCC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa35876
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Founder:
SL6_06_F7
KASP Assay Location:
Unknown
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000040542 | Nonsense | 828 | 1357 | 26 | 39 |
Genomic Location (Zv9):
Chromosome 15 (position 21478427)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 15 | 22581053 |
| GRCz11 | 15 | 22516785 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACTCACCCATGTATCCTCTGGCTTGTTGTTTTCTAGTTCAGCAGTGGA[G/T]AGGAGGAGAAGATCAAGCAAGCAGTGGGCACTTTCTGCAGTAACCAGCCC
Long Flanking Sequence:
TTGGTTAGTTTTTTTTTTTTTATTCATCCAGTGTTTTGTATCCCCCAAATCCCTGTCTGTCTGATACTCTCAGAGCTGTTCTACACGGAGCGAGCTCACGTACGCATGTTGAAGGTCCTAGACAAGGTCTTCTACCAGAAACTCAACCGAGACAACATACTGCCCCCTGCTGACATCAAGTACATATTCACCAACCTGGAGGAAATCATCCAACTCCACGGTATGCTTTTTTTTTTTCTTCAAACTAACATTCATATAAATAATCCAAGCCACATGTCTCATGGCATCTGCTCTTTTAAATTTCAGTGAGAATAGTGGATCAAATGACAGCAATTTGCAAGAAGAACGAGACGTCTGTAATCGACCACATAGGAGACGAGTTGTTGTCTTGGGTAAGGGCTTTTGTTTTGCTGGTAAAATGTGGTGGGCCCTGTCTGGGTGATGAGACTCCCACTCACCCATGTATCCTCTGGCTTGTTGTTTTCTAGTTCAGCAGTGGA[G/T]AGGAGGAGAAGATCAAGCAAGCAGTGGGCACTTTCTGCAGTAACCAGCCCTTCGCCCTGGAGCTCATCAAATCCCGACAGAAGAAGGACCAACGTTTCTCCTCCTTCATGCAGGTGGGTTGATACTCCTTGCTCTGGCCATAGGGTAACCAGAGCTGCAGCGTCAGTTTTGTTCTATAATATGATGTAGGGCTGTTAATATTATTTTACTCTAGTCGAGACATCGCAAAAGTAAGAGATTCTAAAATAGAAACTTGAGCATCGTTGTCAGAGACGTTTAAAACAGAAACTTAATTTAAAATTAAAAATATACCTTTTCCTGTGTTGTGTCAAATTGTGTGTTATTAAAACAAAATATATGTAGCAACTGAGGAGGTTTGGTGTAAAGTAAAATATGAGGGATAGCCACAACAGTACCTTTACCTTATCATGAGTTTTTTTTTTATCGTTTCCTAACTGCAAAAGGCGTGTAAATTCTTCCATTTGTTTTGTGAAAACCGA
Associated Phenotype:
Not determined