ZMP
il6st
Ensembl ID:
ZFIN ID:
Description:
interleukin-6 receptor subunit beta [Source:RefSeq peptide;Acc:NP_001106976]
Human Orthologue:
IL6ST
Human Description:
interleukin 6 signal transducer (gp130, oncostatin M receptor) [Source:HGNC Symbol;Acc:6021]
Mouse Orthologue:
Il6st
Mouse Description:
interleukin 6 signal transducer Gene [Source:MGI Symbol;Acc:MGI:96560]
Alleles
There are 6 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa21663 | Nonsense | Available for shipment | Available now |
| sa1462 | Nonsense | Available for shipment | Available now |
| sa21662 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa21663
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000046045 | Nonsense | 387 | 866 | 8 | 15 |
| ENSDART00000122516 | Nonsense | 380 | 859 | 8 | 15 |
| ENSDART00000146913 | None | None | 306 | None | 6 |
Genomic Location (Zv9):
Chromosome 10 (position 7793914)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5802964 |
| GRCz11 | 10 | 5804183 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAATGTGTAACTATTCCCTGATCATCAGTCAAGATAACCAGGCTTTT[G/T]AAAGTCACGTTATAAAAGCTGATCAGCTCAACCAGAGGTATTCACTGGAA
Long Flanking Sequence:
CAGCTGACGTCAGTGAAGGGTTTGCGTCTTTAATAAACTACGACAGTTTGCATTCAGTAAAAGTTAAGAATGATTAATAAATAAATATGAAACAGTCTCCTAAAAGTCACGTTGCGTCTTCAGTTTCGGGCTCAGGCGCGATTTGCACTCAAACTACAAGCGTACAGTGCCAAAGCCCAAGTGAACCGTGCTCTGGCACACCTCTTCCAACCGAGTTAGGGACGGCCAACTAAACCACGACTGAGCCTGATTCACACTTGTCAAACGAATCGTGAAACGCACCTGGGCACGGTTCGGATAGTATGTGTGCGCCCTTAAATATCAGTAATACTATTTGTGCTGGCTAGAAATCTCTCAAGTGTAAAAAAACAAGTGATCAAGTTAAATATGAATTGTTTTTAAATGATTATTATTATTCTTTCCCATTACAGCCTCCTGTGAAAGCTAATGGAAAAATGTGTAACTATTCCCTGATCATCAGTCAAGATAACCAGGCTTTT[G/T]AAAGTCACGTTATAAAAGCTGATCAGCTCAACCAGAGGTATTCACTGGAAGTGCCACCAGAAGAAAATGCCAGTATTGAAATAACTGCATTCAATTCAGCCGGAGGGTCTCCCAAAACTATTTTGTTCATTCCAAGATCAAATGACGGTACGTTTACAGGATGTTTAGAATTTCAACGTTTTAAGTTCAGCATTTGTGACCACGAAAACAAGTCACAAGTGTCACTTTTTGTTTCAAATTGAGATTTATATATTACTTGATAGCTGAATTAATAAGCTATTCATTGATACTATATATAGTGGTGTGATCTACAGTATACAGTTGAAGTCAGAATTATTAGCCCCCCTCTTAATTTTTTTCCCAATTTCTGTTTAACAGAGAGAAGATTTTTTTTCAACACATTTCTAAACATAATAGGTTTAATAACTCATTTGTAATTTTTCAATTCTTGATTTATTTTATTTTTGTCTTGAGATATTTTTCAAGACACTTCTATAAAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1462
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000046045 | Nonsense | 407 | 866 | 8 | 15 |
| ENSDART00000122516 | Nonsense | 400 | 859 | 8 | 15 |
| ENSDART00000146913 | None | None | 306 | None | 6 |
Genomic Location (Zv9):
Chromosome 10 (position 7793854)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5802904 |
| GRCz11 | 10 | 5804123 |
KASP Assay ID:
554-1387.1 (used for ordering genotyping assays)
KASP Sequence:
TTATAAAAGCTGATCAGCTCAACCAGAGGTATTCACTGGAAGTGCCACCA[G/T]AAGAAAATGCCAGTATTGAAATAACTGCATTCAATTCAGCCGGAGGGTCT
Long Flanking Sequence:
AAGTTAAGAATGATTAATAAATAAATATGAAACAGTCTCCTAAAAGTCACGTTGCGTCTTCAGTTTCGGGCTCAGGCGCGATTTGCACTCAAACTACAAGCGTACAGTGCCAAAGCCCAAGTGAACCGTGCTCTGGCACACCTCTTCCAACCGAGTTAGGGACGGCCAACTAAACCACGACTGAGCCTGATTCACACTTGTCAAACGAATCGTGAAACGCACCTGGGCACGGTTCGGATAGTATGTGTGCGCCCTTAAATATCAGTAATACTATTTGTGCTGGCTAGAAATCTCTCAAGTGTAAAAAAACAAGTGATCAAGTTAAATATGAATTGTTTTTAAATGATTATTATTATTCTTTCCCATTACAGCCTCCTGTGAAAGCTAATGGAAAAATGTGTAACTATTCCCTGATCATCAGTCAAGATAACCAGGCTTTTGAAAGTCACGTTATAAAAGCTGATCAGCTCAACCAGAGGTATTCACTGGAAGTGCCACCA[G/T]AAGAAAATGCCAGTATTGAAATAACTGCATTCAATTCAGCCGGAGGGTCTCCCAAAACTATTTTGTTCATTCCAAGATCAAATGACGGTACGTTTACAGGATGTTTAGAATTTCAACGTTTTAAGTTCAGCATTTGTGACCACGAAAACAAGTCACAAGTGTCACTTTTTGTTTCAAATTGAGATTTATATATTACTTGATAGCTGAATTAATAAGCTATTCATTGATACTATATATAGTGGTGTGATCTACAGTATACAGTTGAAGTCAGAATTATTAGCCCCCCTCTTAATTTTTTTCCCAATTTCTGTTTAACAGAGAGAAGATTTTTTTTCAACACATTTCTAAACATAATAGGTTTAATAACTCATTTGTAATTTTTCAATTCTTGATTTATTTTATTTTTGTCTTGAGATATTTTTCAAGACACTTCTATAAAGATTAAAGTGACATTTAAAGGGCTTAACTAGGTTAATTAGGTTAACTAGGCAGGTTAGGGT
Associated Phenotype:
Normal
| Stage | Entity | Quality | Tag |
|---|---|---|---|
| Larval:Day 5 ZFS:0000037 |
whole organism ZFA:0001094 |
quality PATO:0000001 |
normal PATO:0000461 |
Mutation Details
Allele Name:
sa21662
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000046045 | Essential Splice Site | 436 | 866 | 8 | 15 |
| ENSDART00000122516 | Essential Splice Site | 429 | 859 | 8 | 15 |
| ENSDART00000146913 | None | None | 306 | None | 6 |
Genomic Location (Zv9):
Chromosome 10 (position 7793765)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 10 | 5802815 |
| GRCz11 | 10 | 5804034 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCGGAGGGTCTCCCAAAACTATTTTGTTCATTCCAAGATCAAATGACGG[T/A]ACGTTTACAGGATGTTTAGAATTTCAACGTTTTAAGTTCAGCATTTGTGA
Long Flanking Sequence:
CAAACTACAAGCGTACAGTGCCAAAGCCCAAGTGAACCGTGCTCTGGCACACCTCTTCCAACCGAGTTAGGGACGGCCAACTAAACCACGACTGAGCCTGATTCACACTTGTCAAACGAATCGTGAAACGCACCTGGGCACGGTTCGGATAGTATGTGTGCGCCCTTAAATATCAGTAATACTATTTGTGCTGGCTAGAAATCTCTCAAGTGTAAAAAAACAAGTGATCAAGTTAAATATGAATTGTTTTTAAATGATTATTATTATTCTTTCCCATTACAGCCTCCTGTGAAAGCTAATGGAAAAATGTGTAACTATTCCCTGATCATCAGTCAAGATAACCAGGCTTTTGAAAGTCACGTTATAAAAGCTGATCAGCTCAACCAGAGGTATTCACTGGAAGTGCCACCAGAAGAAAATGCCAGTATTGAAATAACTGCATTCAATTCAGCCGGAGGGTCTCCCAAAACTATTTTGTTCATTCCAAGATCAAATGACGG[T/A]ACGTTTACAGGATGTTTAGAATTTCAACGTTTTAAGTTCAGCATTTGTGACCACGAAAACAAGTCACAAGTGTCACTTTTTGTTTCAAATTGAGATTTATATATTACTTGATAGCTGAATTAATAAGCTATTCATTGATACTATATATAGTGGTGTGATCTACAGTATACAGTTGAAGTCAGAATTATTAGCCCCCCTCTTAATTTTTTTCCCAATTTCTGTTTAACAGAGAGAAGATTTTTTTTCAACACATTTCTAAACATAATAGGTTTAATAACTCATTTGTAATTTTTCAATTCTTGATTTATTTTATTTTTGTCTTGAGATATTTTTCAAGACACTTCTATAAAGATTAAAGTGACATTTAAAGGGCTTAACTAGGTTAATTAGGTTAACTAGGCAGGTTAGGGTAAATAGGCAAGCTAGTGTATTACGATGGTTTGTTCTGTAGACTATCGGAAAAAAATATAGCTTAAAGGGGCTAATCATTTTGTCCCTAA
Associated Phenotype:
Not determined