Busch Lab

ZMP

mef2ca

Ensembl ID:
ENSDARG00000029764
ZFIN ID:
ZDB-GENE-980526-253
Description:
myocyte enhancer factor 2ca [Source:RefSeq peptide;Acc:NP_571387]
Human Orthologue:
MEF2C
Human Description:
myocyte enhancer factor 2C [Source:HGNC Symbol;Acc:6996]
Mouse Orthologue:
Mef2c
Mouse Description:
myocyte enhancer factor 2C Gene [Source:MGI Symbol;Acc:MGI:99458]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa34989 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa2569 Essential Splice Site F2 line generated Not yet available
sa34988 Nonsense Mutation detected in F1 DNA Not yet available
sa31806 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa34989
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027392 Essential Splice Site None 491 2 11
ENSDART00000039551 Essential Splice Site None 449 3 10
ENSDART00000097433 None None 363 None 6
ENSDART00000099134 Essential Splice Site None 465 3 11
ENSDART00000131309 None None 380 None 7
ENSDART00000131731 None None 379 None 7
ENSDART00000134219 None None 86 1 2
ENSDART00000134953 None None 86 None 2
ENSDART00000138962 None None 86 1 2
Genomic Location (Zv9):
Chromosome 10 (position 45131892)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43783340
GRCz11 10 43611720
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGAAACACACTATTTTTCTGATAGAGATCTGTGTGTGTGTTTGTGTGTTC[A/C]GGAACGAAAGCCGGAGTCTTTACAGTGAGCGGAACGAGTGAAGAGGAAAG
Long Flanking Sequence:
TCACAAACGGCATAAACGGCTTTCATCAGCGCAGACACAAGATGTCCTGCATTAACTTGTGATTTAAGGCTCATCCTGACATACACACATACACACATCCAGCCTGATCAGCTAGTTGGAGAAGCGTGAGCTGGACATCACCGTCGACTAGTGGCTAAAGGAGCTTTATATGGATTACACGTCTGAAAAAGCTTAAAGTTACATAAGATCTTGCTGAAAGTTGAGCTCAATGCCTTAAACTAAGATCTCCAGGACTCTTTGTATGCAAACCCATATAAGAATAATGTTTTATTAGATGCTAAATGCATATTTTACACAGGATTTGATCTAAATGACTGGAATCCCATTACAGTAACTACATCATTTGTTGTTATTCCTCTTCCAAGAAACTCTTATTTTTGGCCGCTGTTAACCAGAACGCTCTGTTTCTTCACGCATTGGAGCACTAAGTGAAACACACTATTTTTCTGATAGAGATCTGTGTGTGTGTTTGTGTGTTC[A/C]GGAACGAAAGCCGGAGTCTTTACAGTGAGCGGAACGAGTGAAGAGGAAAGACTGCGCTGAGGAACGACAGAGGAAGGAGAAGGAGACGAGTGTGGACTGTACTTTTGGAAGAGGAAGGAAAAAACAGACAGAAGTCATGGGGAGGAAAAAGATTCAGATTGCGCGGATAATGGACGAACGCAACAGACAGGTAAAAACAAACAGATCTTCGGTTACAATTGTAATCTAAAAGTATAAAAGTAATGTAAAAGTAATCCATAAGTAGTCAGATTACATTATCATAAACGTGTAATCTAAGGAATTATATAAATTTAGTTTTATAATTAATAGCTGAGAACAATTCATAAGTAATCATCTCACACACACACACACACACACGCATGCACACAGAGTGTCATCGTGATTATTTCCAAACATCAAGCACTTGTAATTAGAGTAAACAACTTTATAAACTACTTGTAATCTGACTACAGTTACATTTTTATGGGTTACATATTAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2569
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027392 Essential Splice Site 134 491 5 11
ENSDART00000039551 Essential Splice Site 134 449 6 10
ENSDART00000097433 Essential Splice Site 48 363 2 6
ENSDART00000099134 Essential Splice Site 134 465 6 11
ENSDART00000131309 Essential Splice Site 49 380 2 7
ENSDART00000131731 Essential Splice Site 48 379 2 7
ENSDART00000134219 None None 86 None 2
ENSDART00000134953 None None 86 None 2
ENSDART00000138962 None None 86 None 2
Genomic Location (Zv9):
Chromosome 10 (position 45084058)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43735506
GRCz11 10 43563886
KASP Assay ID:
554-3376.1 (used for ordering genotyping assays)
KASP Sequence:
TGAAATGTCTGCTTTWCGTAATGGACTGATTTCCATGCMTTCTGTTTTCC[A/G]GGCCATCCCTCAGTCTAACTACGACATGCCTGTCTCCATCCCCGTCAGCA
Long Flanking Sequence:
GTGAGACTCATCAATGCAACTTCACAATACTGAGTAGTAAAGGTTAGTTCTTACTGTAGTATCTCACAAACGCTACGTGAGACCTCCTTCCTTTAAGTCTGTCTGTTGTCTGACGCAGCTGAGGGAGGAGGCATGTAGAAACAATAGGCGGGAAAGACTCGTCTTAAAGGCGCAGTACGACAAAACCACCCCCTGCTGGAAATCAGTATAAAACAGCATCTTGTAAAAGGTTTAATGAAAAATCTGATGGGTGACTCGATCTGAAACTTTATATACACATTCTAGAGACGCAAAAGACTTATATTAAATCTGAAAAAAGGGGTAACCTAGGTGCCCTTTAGTATAAATAGTGACTGCATATGAGAACATATAATTGGCCTAATTTACTGTAAACTCTTATATTTGGGTCAACTGTAATATACATGATTCAGGAATGCATGTTTGCGAATGTGAAATGTCTGCTTTACGTAATGGACTGATTTCCATGCATTCTGTTTTCC[A/G]GGCCATCCCTCAGTCTAACTACGACATGCCTGTCTCCATCCCCGTCAGCAACCCCAACAGCCTGATCTACGGCCACCCAGGAGCGTCTCTGGGTAACCCAAACCTGCTGCCGTTGACCCATCCGTCCCTGCAGAGGAACAGCATGTCCCCTGGAGTCACCCACCGGCCCCCGAGTGCAGGAAACACAGGTACCTTGCTCTCCGCTTAACCCGGGACTCCGGATTTTTCCTCATTCTGACGTATTTTACAGAAAAAAAAGTTGGATTCGGCAAGAAAATCCTAGTAGTTTTATTTATCAGGGGTTGCCACAGTGGAATGAACCGCCAACTCATCCAGCATATGTTTAACATAGTGGACGCCCTTCCAGCTGCAACCCAATACTGAGAAACACCCATACACATTCACACACACACATACACTACAGCCATTTAAGTTGATCAATTCCCCTATAGCGCATGTGCTTGGACTGTGGGGGTTCCCACGCCAACACAGGGAGAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34988
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027392 Nonsense 422 491 10 11
ENSDART00000039551 Nonsense 406 449 10 10
ENSDART00000097433 Nonsense 320 363 6 6
ENSDART00000099134 Nonsense 422 465 11 11
ENSDART00000131309 Nonsense 337 380 7 7
ENSDART00000131731 Nonsense 336 379 7 7
ENSDART00000134219 None None 86 None 2
ENSDART00000134953 None None 86 None 2
ENSDART00000138962 None None 86 None 2
Genomic Location (Zv9):
Chromosome 10 (position 45070142)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43721590
GRCz11 10 43549970
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GACTCGGGACGCTCCCCGGTGGACAGTCTCAGCAGCTGCGGCAGCTCGTA[C/A]GACGGCAGCGACCGCGACGAACACCGCGCAAACTTCCACTCGCCCGTGGG
Long Flanking Sequence:
TATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTTAATTTTAGATTTTTACATTTTTTAAATGATTATCATACATTTTTAATTAAGATTTTTCTATTTTAAAATTTACTAAGAAAAAAAAATCGTCAATATTTTAATAACCAAATAAGAAACATATTTTAATATGAGCAAGGTTTCATGATTTGTTGGCTGCAACACTCAGAATTACTCAGAATTTTCTAATTTTCATGTATTTCTTGCTTTCTTCCACAGGAACTGCAGCAGTGCTCAGCTCTGCCAGAGCTCTGCCCTATCTCTGCCGTCCAACCAGAACCTGCACATTAAGTCGGAGCCGGTGTCTCCTCCACGGGATCGAGCGAGCGGGACCCCGGGGCTGTACGGCGTGCCCCAGCAGACCCCGCTGCGGCAGGACTCGGGACGCTCCCCGGTGGACAGTCTCAGCAGCTGCGGCAGCTCGTA[C/A]GACGGCAGCGACCGCGACGAACACCGCGCAAACTTCCACTCGCCCGTGGGACTGATGAGAGCAGCCGAAAATGAGCGGCAGAGCCCGTCCGTCAAGCGCATGCGTCTGTCCGAGGCCGGCTGGGCATCCTGAACACCATTGACAAACAGCCCTGTGAAAAAGTTTGCACCCCCTATATATTGAGTTTCAAGCTTTTCTGTATTCGGACGTAATGCCAAAAAAATTAGATTGACCTTATTCTTCATATTTGAGCAGTCGTCCTGAACACTGCTGAGAAACGGCACTGTGAAAAAGTTTGCACCCCCCATATATTGAATTTCAAGCTTTTCCGTATTCAGACATTATACATAAAAATCTATTGACCTTACTCATATACAAGTGAATGTCCTGAACAATGCTAAGAAACGGCACTGGGAAAAAGTTTGCATCCCCCATATATTGAATTTCAAGCTTTTCCATAATCTGACTTAATGCAAATTTCAAGCTTTTACTTATTCGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31806
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000027392 Nonsense 471 491 11 11
ENSDART00000039551 None None 449 10 10
ENSDART00000097433 None None 363 6 6
ENSDART00000099134 None None 465 11 11
ENSDART00000131309 None None 380 7 7
ENSDART00000131731 None None 379 7 7
ENSDART00000134219 None None 86 None 2
ENSDART00000134953 None None 86 None 2
ENSDART00000138962 None None 86 None 2
Genomic Location (Zv9):
Chromosome 10 (position 45069995)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 43721443
GRCz11 10 43549823
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CGCATGCGTCTGTCCGAGGCCGGCTGGGCATCCTGAACACCATTGACAAA[C/T]AGCCCTGTGAAAAAGTTTGCACCCCCTATATATTGAGTTTCAAGCTTTTC
Long Flanking Sequence:
TACTAAGAAAAAAAAATCGTCAATATTTTAATAACCAAATAAGAAACATATTTTAATATGAGCAAGGTTTCATGATTTGTTGGCTGCAACACTCAGAATTACTCAGAATTTTCTAATTTTCATGTATTTCTTGCTTTCTTCCACAGGAACTGCAGCAGTGCTCAGCTCTGCCAGAGCTCTGCCCTATCTCTGCCGTCCAACCAGAACCTGCACATTAAGTCGGAGCCGGTGTCTCCTCCACGGGATCGAGCGAGCGGGACCCCGGGGCTGTACGGCGTGCCCCAGCAGACCCCGCTGCGGCAGGACTCGGGACGCTCCCCGGTGGACAGTCTCAGCAGCTGCGGCAGCTCGTACGACGGCAGCGACCGCGACGAACACCGCGCAAACTTCCACTCGCCCGTGGGACTGATGAGAGCAGCCGAAAATGAGCGGCAGAGCCCGTCCGTCAAGCGCATGCGTCTGTCCGAGGCCGGCTGGGCATCCTGAACACCATTGACAAA[C/T]AGCCCTGTGAAAAAGTTTGCACCCCCTATATATTGAGTTTCAAGCTTTTCTGTATTCGGACGTAATGCCAAAAAAATTAGATTGACCTTATTCTTCATATTTGAGCAGTCGTCCTGAACACTGCTGAGAAACGGCACTGTGAAAAAGTTTGCACCCCCCATATATTGAATTTCAAGCTTTTCCGTATTCAGACATTATACATAAAAATCTATTGACCTTACTCATATACAAGTGAATGTCCTGAACAATGCTAAGAAACGGCACTGGGAAAAAGTTTGCATCCCCCATATATTGAATTTCAAGCTTTTCCATAATCTGACTTAATGCAAATTTCAAGCTTTTACTTATTCGGACATAATACATGAAAAATCTATTGACTTTACTCATATACAAGTGGATGTCCTGAACAATGCTGAGAAACGGCACTGTGAAAAAGTTTGTACCCCCATATTGAATTTCAAGCTTTTGCTATTCGGGCGTAATACATAAAAATCTACTAA
Associated Phenotype:
Not determined