ZMP

nlk2

Ensembl ID:

ENSDARG00000028793

ZFIN IDs:

ZDB-GENE-080320-1, ZDB-GENE-080320-1

Description:

Nemo-like kinase2 [Source:UniProtKB/TrEMBL;Acc:A9ZMG5]

Human Orthologue:

NLK

Human Description:

nemo-like kinase [Source:HGNC Symbol;Acc:29858]

Mouse Orthologue:

Nlk

Mouse Description:

nemo like kinase Gene [Source:MGI Symbol;Acc:MGI:1201387]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa16109	Essential Splice Site	Available for shipment	Available now
sa24989	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa16109

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000047248	Essential Splice Site	84	458	2	12
ENSDART00000123937	Essential Splice Site	159	533	1	11

Genomic Location (Zv9):

Chromosome 15 (position 29540108)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	30278411
GRCz11	15	30159152

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GATATAGAGCCGGACAGACCGAWCGGATACGGAGCTTTCGGCGTGGTTTG[G/A]TGAGTGGAACWACTTCTGTGTTAACNNAGAATGCTCTAAATAATGCTTCT

Long Flanking Sequence:

CATTTCGGGCTGTTGAGTGAGTGAATGGCTCTGTGCGGAACCACGGCTTCCAATGCCGCGAAAATGATGGCTGCGTACAACGGCGGCACCGCGGCAGTGGCAGCGCATCACCCGCACCATCACCACCAGCTGCCACATCTCCCGCCACCCGCCCACCTCCACCACCATCACCACGCTGGCCAGCATCACCTCCAGCACCCCGGCTCGGCCGCCGCCGTGCACCCCGTACAGCAGCACGCTTCTACGGCCGCGGCCGCTGCTGCTGCGGCGGCGGCGGCGGTGATGCTGAACCCGAGCCAGCAGCAGCCGTACTTCCCCTCGCCCGCTCCTGGACAAGCTCCGGGGCCGGCGGCCGCTGCAGCCCCAGCACAGGTGCAAGCCGCCGCCGCGGCCGCTGTAAAGGTGCACCATCACCACCACCAACACTCGCATCACTTACAACAACAGCTGGATATAGAGCCGGACAGACCGATCGGATACGGAGCTTTCGGCGTGGTTTG[G/A]TGAGTGGAACAACTTCTGTGTTAACAGAGAATGCTCTAAATAATGCTTCTTCTGACGACTTCAAAAGGGCTCTTGAACATTAGCCTAATGTTTATGTAAATCTAAACAACAAGTTTTTATGATCTATTAATATGTGCATTTTAAAAGTTTATTATAATGTTGTGCAAGATATGATTATTAAAAATACATACGCAGAATAGAAAAAAGTTTTGTTATTATGTCACACAGAGCTGGTACACCCCTCATGGGTGCCGCCATGTTTGTCACATGACTAGCTGTGGCATAAGTTCACACCTTACTGTTATTTTGAGATGACAACACCAGCTGTTCATGTCGGCTGACTTGCAATTAGTCTTTTGTATGGACTTATTGTTAACGTCTTTACTTAGAATCTTAATCAATATGTCACAGTTAGGTGATTTACTGGTCACATGGTACAAGCAGTTGCTCAGAAACTCTTGTATTTTGAGTTGTACTAGAATGTGAACAGCTTCTACAAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24989

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000047248	Nonsense	374	458	10	12
ENSDART00000123937	Nonsense	449	533	9	11

Genomic Location (Zv9):

Chromosome 15 (position 29677697)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	15	30416000
GRCz11	15	30296741

KASP Assay ID:

554-7753.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTGGATGAGGGGCGTCTGCGATACCACACCTGCATGTGCAAATGCTGCTA[C/A]ACCACGTCCTCCGGCCGCGTTTACACCAGTGACTTCGAACCCGTCACAAA

Long Flanking Sequence:

TGTGTCAGGAAAATCGAAAACAAAACCAACTGAACTGCGCTCATTTCTGGCGCCCCACTGGATATACAGCGCCCTAAGCATTTGCCTGTGGTGCCTATGCCACGGGCCAGCCCTGAGTTTGCTGAGTGTTGTAAATAACGGCGCTCACCTTCCTCGCGACAGAGCGCATAGGAGATAAATGACGTCAGTACATAATAACCGGTTATGGTTATTACTAAATCGATACCGAATTGTCCGTGTCTGCATCGCGGTGCACCGAAGAAACAATTAATTTTGACACCCCTAATATATATATATATATATATATATATATATAGTATTTATAATATATATTTGTTTTATTTGTTTTATTGTGTTTATATGTTTTACTGTAATATTTAAACTGAACTAATGTGTTCCCCGAAACAGTCGAAGCGAATCTCTGCGAAGGATGCCCTGGCACACCCGTATCTGGATGAGGGGCGTCTGCGATACCACACCTGCATGTGCAAATGCTGCTA[C/A]ACCACGTCCTCCGGCCGCGTTTACACCAGTGACTTCGAACCCGTCACAAACCCCAAGTTTGACGATGGATTTGAGAAGAACCTGACGTCAGTTCGGCAGGTCAAAGGTGAGCCACCAAAAACTCATTCACTTTTACACATTTATGAGGATTACAGTACACAACAGAGATGCACCAATAGACCGGCCAGAAATCCGCATTGGGTTTTTTTTGTTGCTCTAAACTAAAAATAAAACATTAAATTAAACAAATCTAGCAAACATAAACTATTCATTCACTATAAATCCTTCATTTTAATTTCTTTATTAATTATGTGATGTTTTCAACATTAAATTGATGGTACGAATAAGACGAATTAAACCTCTCTAGTACTATCATACCTTGTAATATACTGTACAGTTGAGGTCAAAATTATTAGCCAAATATTATTTATTTTTTATATTTTCCAAATATTTCACAAATTATTTATAACAAAGCAACAATTTCTTTACAATATTTCTTA

Associated Phenotype:

Not determined