Busch Lab

ZMP

diras1a

Ensembl ID:
ENSDARG00000028066
ZFIN ID:
ZDB-GENE-030131-5788
Description:
DIRAS family, GTP-binding RAS-like 1a [Source:RefSeq peptide;Acc:NP_956125]
Human Orthologue:
DIRAS1
Human Description:
DIRAS family, GTP-binding RAS-like 1 [Source:HGNC Symbol;Acc:19127]
Mouse Orthologue:
Diras1
Mouse Description:
DIRAS family, GTP-binding RAS-like 1 Gene [Source:MGI Symbol;Acc:MGI:2183442]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa5591 Essential Splice Site F2 line generated Not yet available
sa35021 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa5591
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000031937 Essential Splice Site None 195 2 2
ENSDART00000031937 Essential Splice Site None 195 2 2
Genomic Location (Zv9):
Chromosome 11 (position 7485655)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 7329758
GRCz11 11 7339597
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATAAGTTGTTTTCTCTACATATAAACCAAGTGAAACTTCTTTCCCTTTTC[A/G]GATCTCAGGGAATAACTGAGTCTTAAGCAGCAGATACTCCAGCAGATAAA
Long Flanking Sequence:
GCCGTATCACTGTCAGTGATCAACATCTTTGCGTCATGTTCAGTCCTGGGATTCTCTACGGGCCAGCGCTCCGCTAGTATCTGAAGGGAAAGCGCGTTCACATTTTCTAGGAAGTGGTACTTTATATTTGGTGATGTACCGTATAGATGTCGATGAGTTCAAGCAAAAGATCCGAACTCAACTCGATGCATTAATTCAACTCTGATTCGACTGTTTTGTTAAAGATTCAATAGTTTTAAACACGATGCACTTTCAGATTTATACCTCAGCTGAATGTTTTTATTTACTTGAAGCGGTGTTACACACTGCATGGAAGCTCATTTTTAGAAACCCATAATAGGGGCTCTTTAATATTTCCATATGTTCATGAAACAAATGAATCTATTGGGTTCCTACTGTTTCTAGAATCTCTCATCAATTGAAAACATTCCAAGTATTGTATATGAACTGATAAGTTGTTTTCTCTACATATAAACCAAGTGAAACTTCTTTCCCTTTTC[A/G]GATCTCAGGGAATAACTGAGTCTTAAGCAGCAGATACTCCAGCAGATAAACCAGAGCAGCATGCCAGAGCAGAGTAACGATTACCGAGTGGTGGTCTTTGGAGCAGGGGGTGTAGGCAAGAGCTCCCTGGTTCTGCGCTTTGTTAAGGGCACCTTCAGGGACACCTACATCCCAACAGTGGAGGACACGTACCGGCAGGTCATCAGCTGCGACAAGAGCGTATGCACACTGGAGATCACCGACACCACCGGCAGCCACCAGTTCCCGGCTATGCAGCGTCTGTCCATCTCCAAGGGCCATGCCTTCATCCTGGTCTACTCCATCACCAGCAGGCAATCCCTGGAGGAGCTCAAGCCCATCTACCAGCAAGTGCTGGCCATCAAAGGCAACGTGGAGAACATCCCCATCATGCTTGTGGGTAACAAGAGCGATGAGACCCAGCGCGAGGTGGAGACCAAGGAGGGCGAGGCTCAGGCAAACACCTGGAAGTGCGCGTTCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35021
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000031937 Nonsense 191 195 2 2
Genomic Location (Zv9):
Chromosome 11 (position 7486286)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 7330389
GRCz11 11 7340228
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCTGAACATGCGCTCCAGCAAGCAGAGACGGGCAGACAAGCTGAAGGCC[A/T]AGTGCAGTGTGATGTAGGAAGCCGCATCTATGGTCGCATCACTCAACTGA
Long Flanking Sequence:
TTCTGCGCTTTGTTAAGGGCACCTTCAGGGACACCTACATCCCAACAGTGGAGGACACGTACCGGCAGGTCATCAGCTGCGACAAGAGCGTATGCACACTGGAGATCACCGACACCACCGGCAGCCACCAGTTCCCGGCTATGCAGCGTCTGTCCATCTCCAAGGGCCATGCCTTCATCCTGGTCTACTCCATCACCAGCAGGCAATCCCTGGAGGAGCTCAAGCCCATCTACCAGCAAGTGCTGGCCATCAAAGGCAACGTGGAGAACATCCCCATCATGCTTGTGGGTAACAAGAGCGATGAGACCCAGCGCGAGGTGGAGACCAAGGAGGGCGAGGCTCAGGCAAACACCTGGAAGTGCGCGTTCATGGAAACATCAGCCAAGACCAACACCAATGTGAAGGAGCTTTTTCAAGAGCTCCTGAATCTGGATAAGAAGCGGGATATGAGTCTGAACATGCGCTCCAGCAAGCAGAGACGGGCAGACAAGCTGAAGGCC[A/T]AGTGCAGTGTGATGTAGGAAGCCGCATCTATGGTCGCATCACTCAACTGACTCTTCGAAAATGTACATAAGTCCCTCACTTTAAAGGAAGAGTACGCCCTAAGATAATGGAACTCCTGTCATGATTTGTATGCTGCCGCTTTAAACCTACATGACTTATTTTTCATTTTTCAAGAATTATATTAGCTGTACTCCCATAAACGTTGTTCACAGGACCTGTCAAGTGTATTCCAAATCTCAAAATGGAAAGATCATAACCATATAACTAATTCAGAACGAGTTTGAGAGCTGATTCTTTAAAAAAAAAACGATGAAGTTCTTGTATTAACATACTACATTTACTTAAAGTGTAGGTACAGATTACAGTAATGTAACCTTCTGGCAGTTTTAGTCATGGACCACATACAGTACTGTGGTTGTTTAGCACCATAACCATTCTTATATTTCATTTTTGTGATTAACCGAAGAAAGCCATGTATGTTTAAGACGAGTAAACCATGA
Associated Phenotype:
Not determined