ZMP

top1mt

Ensembl ID:

ENSDARG00000027824

ZFIN ID:

ZDB-GENE-040624-2

Description:

DNA topoisomerase I, mitochondrial [Source:RefSeq peptide;Acc:NP_001001838]

Human Orthologues:

TOP1, TOP1MT

Human Descriptions:

topoisomerase (DNA) I [Source:HGNC Symbol;Acc:11986]
topoisomerase (DNA) I, mitochondrial [Source:HGNC Symbol;Acc:29787]

Mouse Orthologues:

Top1, Top1mt

Mouse Descriptions:

DNA topoisomerase 1, mitochondrial Gene [Source:MGI Symbol;Acc:MGI:1920210]
topoisomerase (DNA) I Gene [Source:MGI Symbol;Acc:MGI:98788]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa14373	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa14373

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000025550	Essential Splice Site	147	262	4	7

Genomic Location (Zv9):

Chromosome 24 (position 43774280)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	42138848
GRCz11	24	42012263

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GGGCAGCACCCAAAACMTTCGAGAAGTCCATGCAGCTGCTGCAAGARAAG[G/A]TGAGCAGACAAATACACACRCAATACTACACAWTAACNNNNNNNNNNAMA

Long Flanking Sequence:

AATGTCAATCACAGTGTTTCTGCATCAAGTCTGATTAGAACAAACACAATTAGTTCATGTTGAGCATCAGAGGCTGCTGGAGATATTTTCATTTAAACCCATTATGAATGTGATTTCTGCATAATAGGTGGCCTTTAATATAACAACAGCTTTATAGAATGTATGTTTTATAATAATAAAAGCTTTCCCGGATTGACAACAGGATGAACGCTTCATCATGGCCTTTTGAAAGGGTGTGTTGTGTATTGAGTTCTGCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTAGATGACGGCACAGTGGAGGAGAAGATCCTGTCCTACAACCGCGCCAACAGAGCTGTGGCCATACTCTGCAACCACCAGAGGGCAGCACCCAAAACATTCGAGAAGTCCATGCAGCTGCTGCAAGAGAAG[G/A]TGAGCAGACAAATACACACGCAATACTACACAATAACACACAATACTACACAATAACACACAATACTACACATTAACACACAAAAACACACAATACTACACATTAACACACAATACTACACAATAACACACATTAACACACAATACTACACAATCTGAGACTTTCAGGAGCACTGAGATGAACACAGGTCTACTTCTGGAATATTATAATGTCTATTATTCCAGATGTTGAAAGTCAGGGATTTAGTAAAGTTTATATTCTTTTGTCCAAGTCATGGAATATCAGGGAATTTGTTTATCATCTTTTAAAGTGCGTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTCAGTATACAGCACTCTGCACAAATGTGTTCGTCCTCTTTTGAAAATAACTTCTGTCTGAATTTCACAGAAAAATGGAGGATCAACTTATTGCAAAAAAGTGCAAACTAGATTTTATGAAATATTTTTCCCCAAAAT

Associated Phenotype:

Not determined